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Hedgehog Pathway Disruption Alters Urothelial Differentiation and Continence Mechanisms in the Female Mouse Lower Urinary Tract | American Journal of Physiology-Renal Physiology | American Physiological Society

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54.241.53.176/033a50b02f48fee06bc27bd5cbea72dc0e5b80b5/tanaka-et-al-2026-hedgehog-pathway-disruption-alters-urothelial-differentiation-and-continence-mechanisms-in-the-female-html.html
Apr 2026
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Stem cell control in the lung by an autocrine injury-activated Igf complex

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1. scibot 21 Apr 2026
  
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science.org/doi/10.1126/science.adt1310
Nov 2025
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Hypoxia promotes airway differentiation in the human lung epithelium

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1. scibot 21 Nov 2025
  
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  DOI: 10.1016/j.stem.2025.09.007
  
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pmc.ncbi.nlm.nih.gov/articles/PMC7618356/
Oct 2025
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Pharmacologic inhibition of IRE1α-dependent decay protects alveolar epithelial identity and prevents pulmonary fibrosis in mice

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  DOI: 10.1172/JCI184522
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12520674/
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Hypoxia promotes airway differentiation in the human lung epithelium

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  DOI: 10.1016/j.stem.2025.09.007
  
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pmc.ncbi.nlm.nih.gov/articles/PMC7618356/
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Single-cell analysis uncovers preserved prostate cancer lineages and universally altered pathways in Matrigel-free patient-derived organoids

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  DOI: 10.1016/j.celrep.2025.116352
  
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sciencedirect.com/science/article/pii/S2211124725011234
Jul 2025
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Conserved signals control self-organization and symmetry breaking of murine bilayered epithelia during development and regeneration

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  DOI: 10.1016/j.devcel.2025.06.007
  
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sciencedirect.com/science/article/pii/S1534580725003624
Jun 2025
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Neuroendocrine cells orchestrate regeneration through Desert hedgehog signaling

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  DOI: 10.1016/j.cell.2025.05.012
  
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sciencedirect.com/science/article/pii/S0092867425005628
May 2025
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Transcriptional landscapes underlying Notch-induced lineage conversion and plasticity of mammary basal cells

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1. scibot 20 May 2025
  
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  DOI: 10.1038/s44318-025-00424-1
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12084385/
Dec 2024
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Morphogenesis and regeneration share a conserved core transition cell state program that controls lung epithelial cell fate

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1. scibot 12 Dec 2024
  
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  DOI: 10.1016/j.devcel.2024.11.017
  
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sciencedirect.com/science/article/pii/S1534580724006993
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Cell competition drives bronchiolization and pulmonary fibrosis

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1. scibot 11 Dec 2024
  
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  DOI: 10.1038/s41467-024-54997-2
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11621346/
Jul 2024
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A specialized population of monocyte-derived tracheal macrophages promote airway epithelial regeneration through a CCR2-dependent mechanism

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1. scibot 10 Jul 2024
  
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  DOI: 10.1016/j.isci.2024.110169
  
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sciencedirect.com/science/article/pii/S2589004224013944
May 2024
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Cell competition drives bronchiolization and pulmonary fibrosis

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1. scibot 23 May 2024
  
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  DOI: 10.21203/rs.3.rs-4177351/v1
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11092845/
Apr 2024
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Defining the contribution of Troy-positive progenitor cells to the mouse esophageal epithelium

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1. scibot 02 Apr 2024
  
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  DOI: 10.1016/j.devcel.2024.03.011
  
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  DOI: 10.1016/j.devcel.2024.03.011
  
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sciencedirect.com/science/article/pii/S1534580724001795
Aug 2023
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Down Syndrome is Associated with Altered Frequency and Functioning of Tracheal Multiciliated Cells, and Response to Influenza Virus Infection

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1. scibot 10 Aug 2023
  
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  DOI: 10.1016/j.isci.2023.107361
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10405068/
May 2023
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Loss of fibroblast growth factor receptor 2 (FGFR2) leads to defective bladder urothelial regeneration after Cyclophosphamide injury

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1. scibot 06 May 2023
  
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  DOI: 10.1016/j.ajpath.2020.12.011
  
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sciencedirect.com/science/article/pii/S0002944020305988
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Immune mechanisms shape the clonal landscape during early progression of prostate cancer

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1. scibot 06 May 2023
  
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  DOI: 10.1016/j.devcel.2023.04.010
  
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sciencedirect.com/science/article/pii/S1534580723001806
Feb 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Dynamic states of cervical epithelia during pregnancy and epithelial barrier disruption

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  DOI: 10.1016/j.isci.2023.105953
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9883190/
Dec 2022
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ΔNp63 drives dysplastic alveolar remodeling and restricts epithelial plasticity upon severe lung injury

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  DOI: 10.1016/j.celrep.2022.111805
  
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sciencedirect.com/science/article/pii/S221112472201693X
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A human fetal lung cell atlas uncovers proximal-distal gradients of differentiation and key regulators of epithelial fates

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  DOI: 10.1016/j.cell.2022.11.005
  
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sciencedirect.com/science/article/pii/S0092867422014155
Oct 2022
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Histone methylation antagonism drives tumor immune evasion in squamous cell carcinomas

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sciencedirect.com/science/article/pii/S1097276522008966
Jun 2022
physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com

Durability of and role of AKT in FGF7p urothelial protection against cyclophosphamide

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1. scibot 30 Jun 2022
  
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  DOI: 10.14814/phy2.15358
  
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physoc.onlinelibrary.wiley.com/doi/10.14814/phy2.15358
Jan 2022
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Fine-tuning of β-catenin in mouse thymic epithelial cells is required for postnatal T-cell development

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1. scibot 26 Jan 2022
  
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  DOI: 10.7554/eLife.69088
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8769649/
Sep 2021
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UV-induced reduction in Polycomb repression promotes epidermal pigmentation

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  DOI: 10.1016/j.devcel.2021.08.006
  
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sciencedirect.com/science/article/pii/S1534580721006365
Jul 2021
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Yap/Taz inhibit goblet cell fate to maintain lung epithelial homeostasis

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  DOI: 10.1016/j.celrep.2021.109347
  
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sciencedirect.com/science/article/pii/S2211124721007233
May 2021
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RANK links senescence to stemness in the mammary epithelia, delaying tumor onset but increasing tumor aggressiveness

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  DOI: 10.1016/j.devcel.2021.04.022
  
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sciencedirect.com/science/article/pii/S1534580721003609
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Bacteria induce skin regeneration via IL-1β signaling

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  DOI: 10.1016/j.chom.2021.03.003
  
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sciencedirect.com/science/article/pii/S1931312821001311
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Derivation of Airway Basal Stem Cells from Human Pluripotent Stem Cells

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  DOI: 10.1016/j.stem.2020.09.017
  
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sciencedirect.com/science/article/pii/S1934590920304926
Apr 2021
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Airway basal stem cells generate distinct subpopulations of PNECs

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sciencedirect.com/science/article/pii/S2211124721003259
Mar 2021
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Impact of sex, androgens, and prostate size on C57BL/6J mouse urinary physiology: urethral histology

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1. scibot 04 Mar 2021
  
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  DOI: 10.1152/ajprenal.00540.2019
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7099510/
Sep 2020
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An immunohistochemical prostate cell identification key indicates that aging shifts procollagen 1A1 production from myofibroblasts to fibroblasts in dogs prone to prostate-related urinary dysfunction

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1. scibot 23 Sep 2020
  
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  DOI: 10.1371/journal.pone.0232564
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7390344/
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A Cellular Anatomy of the Normal Adult Human Prostate and Prostatic Urethra

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1. scibot 04 Sep 2020
  
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  DOI: 10.1016/j.celrep.2018.11.086
  
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cell.com/cell-reports/fulltext/S2211-1247(18)31877-1
Jan 2020
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Polycomb Repressive Complex 1 Controls Maintenance of Fungiform Papillae by Repressing Sonic Hedgehog Expression

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.celrep.2019.06.011
  
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sciencedirect.com/science/article/pii/S2211124719307697
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Keratinocyte growth factor reduces injury and leads to early recovery from cyclophosphamide bladder injury

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.ajpath.2019.09.015
  
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sciencedirect.com/science/article/pii/S0002944019307679
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Epithelial DNA methyltransferase-1 regulates cell survival, growth and maturation in developing prostatic buds

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1. scibot 13 Jan 2020
  
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  RRID:AB_2565054
  
  DOI: 10.1016/j.ydbio.2019.01.011
  
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1. scibot 12 Jan 2020
  
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  RRID:AB_2565054
  
  DOI: 10.1016/j.celrep.2018.11.086
  
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  Curator: @evieth
  
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Nov 2018
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3D Modeling of Esophageal Development using Human PSC-Derived Basal Progenitors Reveals a Critical Role for Notch Signaling

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1. scibot 05 Nov 2018
  
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1. scibot 05 Nov 2018
  
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TCF7L1 promotes skin tumorigenesis independently of β-catenin through induction of LCN2.

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1. scibot 05 Nov 2018
  
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