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TIGIT-targeted IL-12 fusion protein engages NK and CD8+ T cells for potent tumor immunotherapy

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1. scibot 17 Jun 2026
  
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  DOI: 10.1016/j.xcrm.2026.102876
  
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sciencedirect.com/science/article/pii/S2666379126002934
May 2026
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Targeting ADAR1 p150 triggers tumor inhibition and antitumor immunity to overcome immunotherapy resistance

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1. scibot 22 May 2026
  
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  DOI: 10.1016/j.isci.2026.115978
  
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sciencedirect.com/science/article/pii/S2589004226013532
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VSIG4 restricts hepatocellular carcinoma control by suppressing tumor-specific CD8+ T cell immunity in the tumor microenvironment

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1. scibot 05 May 2026
  
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  DOI: 10.1158/2326-6066.CIR-25-0836
  
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aacrjournals.org/cancerimmunolres/article/14/5/718/784454/VSIG4-Restricts-Hepatocellular-Carcinoma-Control
Apr 2026
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Skin inflammation and itch response are independently regulated by distinct nociceptor subsets

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1. scibot 17 Apr 2026
  
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  DOI: 10.1016/j.immuni.2026.03.020
  
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sciencedirect.com/science/article/pii/S1074761326001317
Mar 2026
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Engineered MSCs enable bone marrow-targeted immunomodulation

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1. scibot 27 Mar 2026
  
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  DOI: 10.1016/j.stem.2026.03.003
  
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sciencedirect.com/science/article/pii/S193459092600113X
Feb 2026
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CCL3 is produced by aged neutrophils across cancers and promotes tumor growth

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1. scibot 06 Feb 2026
  
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  DOI: 10.1016/j.ccell.2026.01.006
  
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sciencedirect.com/science/article/pii/S1535610826000450
Jan 2026
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Aromatic microbial metabolite hippuric acid enhances inflammatory responses in macrophages via TLR-MyD88 signaling and lipid remodeling

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1. scibot 06 Jan 2026
  
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  DOI: 10.1016/j.celrep.2025.116749
  
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sciencedirect.com/science/article/pii/S2211124725015219
Dec 2025
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ARAP2 regulates responses to interferon-gamma by restricting SOCS1

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1. scibot 16 Dec 2025
  
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  DOI: 10.1016/j.celrep.2025.116667
  
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sciencedirect.com:5037/science/article/pii/S2211124725014391
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Cryptococcus exploits delayed microglial activation, and microglial osteopontin/Spp1 impairs peripheral host control

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1. scibot 04 Dec 2025
  
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  DOI: 10.1016/j.chom.2025.11.008
  
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sciencedirect.com:5037/science/article/pii/S1931312825004688
Oct 2025
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RAF-independent MEK mutations drive refractory histiocytic neoplasms but respond to ERK inhibition

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1. scibot 28 Oct 2025
  
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  DOI: 10.1016/j.ccell.2025.09.014
  
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sciencedirect.com/science/article/pii/S1535610825004064
Sep 2025
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1-s2.0-S2772572325001967-main-html.html

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1. scibot 19 Sep 2025
  
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  DOI: 10.1016/j.gastha.2025.100809
  
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52.53.155.43/0130feb0d6482fc1e66e3faa846240ab37c29c9f/1-s2.0-S2772572325001967-main-html.html
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OGFOD1 enables AML chemo- and nutrient stress resistance by regulating protein synthesis

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1. scibot 17 Sep 2025
  
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  DOI: 10.1016/j.cmet.2025.08.008
  
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sciencedirect.com/science/article/pii/S155041312500381X
Jul 2025
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Mitochondrial complex IV remodeling in tumor-associated macrophages amplifies interferon signaling and promotes anti-tumor immunity

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1. scibot 01 Jul 2025
  
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  DOI: 10.1016/j.immuni.2025.06.006
  
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sciencedirect.com/science/article/pii/S1074761325002754
Jun 2025
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De-coupling immune parameters and toxicity associated with IL-12 agonism

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1. scibot 13 Jun 2025
  
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  DOI: 10.1016/j.celrep.2025.115840
  
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sciencedirect.com/science/article/pii/S2211124725006114
May 2025
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Clonal hematopoiesis-associated motoric deficits caused by monocyte-derived microglia accumulating in aging mice

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1. scibot 16 May 2025
  
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  DOI: 10.1016/j.celrep.2025.115609
  
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sciencedirect.com/science/article/pii/S2211124725003808
Mar 2025
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Modulation of lipid nanoparticle-formulated plasmid DNA drives innate immune activation promoting adaptive immunity

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1. scibot 24 Mar 2025
  
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  DOI: 10.1016/j.xcrm.2025.102035
  
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cell.com/cell-reports-medicine/fulltext/S2666-3791(25)00108-9
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Lymph node macrophages drive immune tolerance and resistance to cancer therapy by induction of the immune-regulatory cytokine IL-33

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1. scibot 07 Mar 2025
  
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  RRID:AB_2565431
  
  DOI: 10.1016/j.ccell.2025.02.017
  
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sciencedirect.com/science/article/pii/S1535610825000698
Feb 2025
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Extracellular vesicles from the lung pro-thrombotic niche drive cancer-associated thrombosis and metastasis via integrin beta 2

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1. scibot 13 Feb 2025
  
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  DOI: 10.1016/j.cell.2025.01.025
  
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sciencedirect.com/science/article/pii/S0092867425000947
Dec 2024
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IL-17A/CEBPβ/OPN/LYVE-1 axis inhibits anti-tumor immunity by promoting tumor-associated tissue-resident macrophages

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1. scibot 12 Dec 2024
  
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  DOI: 10.1016/j.celrep.2024.115039
  
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sciencedirect.com/science/article/pii/S2211124724013901
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Synovial tissue myeloid dendritic cell subsets exhibit distinct tissue-niche localization and function in health and rheumatoid arthritis

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1. scibot 02 Dec 2024
  
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  DOI: 10.1016/j.immuni.2024.11.004
  
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sciencedirect.com/science/article/pii/S1074761324005193
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A pan-family screen of nuclear receptors in immunocytes reveals ligand-dependent inflammasome control

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1. scibot 02 Dec 2024
  
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  DOI: 10.1016/j.immuni.2024.10.010
  
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sciencedirect.com/science/article/pii/S1074761324004904
Nov 2024
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Tissue-colonizing disseminated tumor cells secrete prostaglandin E2 to promote NK cell dysfunction and evade anti-metastatic immunity

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1. scibot 20 Nov 2024
  
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  DOI: 10.1016/j.celrep.2024.114855
  
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sciencedirect.com/science/article/pii/S2211124724012063
Sep 2024
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Notch signaling regulates macrophage-mediated inflammation in metabolic dysfunction-associated steatotic liver disease

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1. scibot 26 Sep 2024
  
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  DOI: 10.1016/j.immuni.2024.08.016
  
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sciencedirect.com/science/article/pii/S107476132400414X
Jun 2024
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Suppression of tumor cell lactate-generating signaling pathways eradicates murine PTEN/p53-deficient aggressive-variant prostate cancer via macrophage phagocytosis

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1. scibot 07 Jun 2024
  
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  DOI: 10.1158/1078-0432.CCR-23-1441
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10841690/
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Ebola virus-induced eye sequelae: a murine model for evaluating glycoprotein-targeting therapeutics

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1. scibot 04 Jun 2024
  
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  DOI: 10.1016/j.ebiom.2024.105170
  
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sciencedirect.com/science/article/pii/S2352396424002056
May 2024
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2024.03.02.583119v1.full-html.html

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1. scibot 16 May 2024
  
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  AB_2565431
  
  DOI: 10.1128/iai.00004-13
  
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52.53.155.43/6a71e4d7810341343df9a7e9b0f30ef2509d5125/2024.03.02.583119v1.full-html.html
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Classical monocyte ontogeny dictates their functions and fates as tissue macrophages

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1. scibot 16 May 2024
  
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  DOI: 10.1016/j.immuni.2024.04.019
  
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sciencedirect.com/science/article/pii/S1074761324002243
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Targeting the HSP47-collagen axis inhibits brain metastasis by reversing M2 microglial polarization and restoring anti-tumor immunity

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1. scibot 14 May 2024
  
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  DOI: 10.1016/j.xcrm.2024.101533
  
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sciencedirect.com/science/article/pii/S2666379124002027
Mar 2024
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Microbial metabolite enhances immunotherapy efficacy by modulating T cell stemness in pan-cancer

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1. scibot 15 Mar 2024
  
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  DOI: 10.1016/j.cell.2024.02.022
  
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cell.com/cell/fulltext/S0092-8674(24)00224-1
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Species-specific NLRP3 regulation and its role in CNS autoinflammatory diseases

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  DOI: 10.1016/j.celrep.2024.113852
  
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sciencedirect.com/science/article/pii/S2211124724001803
Feb 2024
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Gut complement induced by the microbiota combats pathogens and spares commensals

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  DOI: 10.1016/j.cell.2023.12.036
  
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sciencedirect.com/science/article/pii/S0092867424000011
Jan 2024
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Integrative analysis of neuroblastoma by single-cell RNA sequencing identifies the NECTIN2-TIGIT axis as a target for immunotherapy

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1. scibot 11 Jan 2024
  
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  DOI: 10.1016/j.ccell.2023.12.008
  
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  DOI: 10.1016/j.ccell.2023.12.008
  
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sciencedirect.com/science/article/pii/S1535610823004361
Oct 2023
www.biorxiv.org www.biorxiv.org

NFAT5-dependent transcriptional stress control of endothelial cells prevents maladaptive remodeling of pulmonary arterioles in the hypoxic lung

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1. scibot 27 Oct 2023
  
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  DOI: 10.1101/2023.10.18.563022
  
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biorxiv.org/content/10.1101/2023.10.18.563022v1
Sep 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The dual lipid desaturase/hydroxylase DEGS2 controls phytoceramide levels necessary to counter intestinal inflammation

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1. scibot 17 Sep 2023
  
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  RRID:AB_2565431
  
  DOI: 10.1242/dmm.050043
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10499023/
Aug 2023
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Loss of CD4+ T cell-intrinsic arginase 1 accelerates Th1 response kinetics and reduces lung pathology during influenza infection

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1. scibot 12 Aug 2023
  
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Jul 2023
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QUAS-R: An SLC1A5-mediated glutamine uptake assay with single-cell resolution reveals metabolic heterogeneity with immune populations

1
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A distinct stimulatory cDC1 subpopulation amplifies CD8+ T cell responses in tumors for protective anti-cancer immunity

1
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Jun 2023
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Ketogenic diet promotes tumor ferroptosis but induces relative corticosterone deficiency that accelerates cachexia

1
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Tumor-derived prostaglandin E2 programs cDC1 dysfunction to impair intratumoral orchestration of anti-cancer T cell responses

1
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VEGFR-3 signaling restrains the neuron-macrophage crosstalk during neurotropic viral infection

1
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Apr 2023
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cDC1 coordinate innate and adaptive responses in the omentum required for T cell priming and memory

1
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Mar 2023
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T helper 2 cells control monocyte to tissue-resident macrophage differentiation during nematode infection of the pleural cavity

1
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Feb 2023
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Crosstalk between ILC2s and Th2 cells varies among mouse models

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Jan 2023
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Identification of the mouse Kupffer cell receptors recognizing pneumococcal capsules by affinity screening

1
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Immunity to the microbiota promotes sensory neuron regeneration

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Lymphatic PD-L1 Expression Restricts Tumor-Specific CD8+ T-cell Responses

1
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Dec 2022
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Structural and functional distinctions of co-resident microglia and monocyte-derived macrophages after retinal degeneration

1
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Nov 2022
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Structural basis of activation and antagonism of receptor signaling mediated by interleukin-27

1
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Oct 2022
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Cbl-b Restrains Priming of Pathogenic Th17 Cells via the Inhibition of IL-6 Production by Macrophages

1
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Aug 2022
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Heritable vaginal bacteria influence immune tolerance and relate to early-life markers of allergic sensitization in infancy

1
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Jul 2022
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An improved organotypic cell culture system to study tissue-resident macrophages ex vivo

1
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Androgen receptor-mediated CD8+ T cell stemness programs drive sex differences in antitumor immunity

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Deprenyl reduces inflammation during acute SIV infection

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Mar 2022
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Type 1 innate lymphoid cells regulate the onset of Toxoplasma gondii-induced neuroinflammation

1
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Dec 2021
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Secreted osteopontin from CD4+ T cells limits acute graft-versus-host disease

1
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Nov 2021
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Fragmentation of tissue-resident macrophages during isolation confounds analysis of single-cell preparations from mouse hematopoietic tissues

1
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Single-cell transcriptomics reveals opposing roles of Shp2 in Myc-driven liver tumor cells and microenvironment

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Aug 2021
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Commensal Clostridiales strains mediate effective anti-cancer immune response against solid tumors

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Untitled document

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  DOI: 10.1016/j.celrep.2019.03.082
  
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Jul 2021
onlinelibrary.wiley.com onlinelibrary.wiley.com

Transcriptional profiling of breast cancer‐associated lymphatic vessels reveals VCAM‐1 as regulator of lymphatic invasion and permeability

1
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  CD11b‐BV605
  
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onlinelibrary.wiley.com/doi/full/10.1002/ijc.32594
May 2021
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Intestinal barrier dysfunction plays an integral role in arthritis pathology and can be targeted to ameliorate disease

1
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Dectin-1 limits autoimmune neuroinflammation and promotes myeloid cell-astrocyte crosstalk via Card9-independent expression of Oncostatin M

1
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The Gut Microbiome Regulates Psychological-Stress-Induced Inflammation

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CD276 expression enables squamous cell carcinoma stem cells to evade immune surveillance

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  DOI: 10.1016/j.stem.2021.04.011
  
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Apr 2021
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Sirt2 Inhibition Enhances Metabolic Fitness and Effector Functions of Tumor-Reactive T Cells

1
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  DOI: 10.1016/j.cmet.2020.07.008
  
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Visualizing Synaptic Transfer of Tumor Antigens among Dendritic Cells

1
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  DOI: 10.1016/j.ccell.2020.05.002
  
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Oct 2020
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Hhex Directly Represses BIM-Dependent Apoptosis to Promote NK Cell Development and Maintenance

1
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  DOI: 10.1016/j.celrep.2020.108285
  
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Sep 2020
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Checkpoint Receptor TIGIT Expressed on Tim-1+ B Cells Regulates Tissue Inflammation

1
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C/EBPβ-Dependent Epigenetic Memory Induces Trained Immunity in Hematopoietic Stem Cells

1
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Microbiota-Derived Metabolites Suppress Arthritis by Amplifying Aryl-Hydrocarbon Receptor Activation in Regulatory B Cells

1
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Transcriptomic analysis reveals diverse gene expression changes in airway macrophages during experimental allergic airway disease

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Aryl Hydrocarbon Receptor Contributes to the Transcriptional Program of IL-10-Producing Regulatory B Cells

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Untitled document

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Identification of an Early Unipotent Neutrophil Progenitor with Pro-tumoral Activity in Mouse and Human Bone Marrow

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LSD1 Ablation Stimulates Anti-tumor Immunity and Enables Checkpoint Blockade

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Blocking Neuronal Signaling to Immune Cells Treats Streptococcal Invasive Infection

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Self-Renewal and Toll-like Receptor Signaling Sustain Exhausted Plasmacytoid Dendritic Cells during Chronic Viral Infection

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Non-classical Immunity Controls Microbiota Impact on Skin Immunity and Tissue Repair

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