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Cancer-associated adipocytes mediate CD8+T cell dysfunction via FGF21-driven lipolysis

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sciencedirect.com/science/article/pii/S2211124725012975
Oct 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

TYK2 Promotes Immunosurveillance of Colorectal Cancer Liver Metastasis

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1. scibot 23 Oct 2025
  
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pmc.ncbi.nlm.nih.gov/articles/PMC7618269/
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Urothelial collective-gliding response acts as a toll-like receptor 4-associated defense mechanism

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sciencedirect.com/science/article/pii/S2589004225018140
Aug 2025
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Polyamines regulate adaptive antitumor immunity by functional specialization of regulatory T cells

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1. scibot 01 Aug 2025
  
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sciencedirect.com/science/article/pii/S1074761325003164
Jul 2025
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Adoptively transferred Th17 cells cooperate with host B cells to achieve durable tumor immunity

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1. scibot 25 Jul 2025
  
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sciencedirect.com/science/article/pii/S1535610825002727
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Temporally programmed STING nanoadjuvant delivery unlocks synergistic chemotherapy-induced antitumor immunity

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  DOI: 10.1126/sciadv.adw0797
  
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science.org/doi/10.1126/sciadv.adw0797
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Temporally programmed STING nanoadjuvant delivery unlocks synergistic chemotherapy-induced antitumor immunity

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pmc.ncbi.nlm.nih.gov/articles/PMC12273768/
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HPV16-Expressing Tumors Release Multiple IL1 Ligands to Orchestrate Systemic Immunosuppression Whose Disruption Enables Efficacy of a Therapeutic Vaccine

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1. scibot 08 Jul 2025
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12223509/
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APOE protects against severe infection with Mycobacterium tuberculosis by restraining production of neutrophil extracellular traps

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1. scibot 02 Jul 2025
  
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  DOI: 10.1371/journal.ppat.1013267
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12201663/
Jun 2025
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Targeting the CD40 costimulatory receptor to improve virotherapy efficacy in diffuse midline gliomas

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1. scibot 28 Jun 2025
  
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sciencedirect.com/science/article/pii/S2666379125002770
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ILC3s sense gut microbiota through STING to initiate immune tolerance

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1. scibot 17 Jun 2025
  
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  DOI: 10.1016/j.immuni.2025.05.016
  
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De-coupling immune parameters and toxicity associated with IL-12 agonism

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1. scibot 13 Jun 2025
  
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  DOI: 10.1016/j.celrep.2025.115840
  
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sciencedirect.com/science/article/pii/S2211124725006114
Apr 2025
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Rorγt-positive dendritic cells are required for the induction of peripheral regulatory T cells in response to oral antigens

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1. scibot 05 Apr 2025
  
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  DOI: 10.1016/j.cell.2025.03.020
  
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sciencedirect.com/science/article/pii/S0092867425002934
Feb 2025
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Lung CD4+ resident memory T cells use airway secretory cells to stimulate and regulate onset of allergic airway neutrophilic disease

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1. scibot 20 Feb 2025
  
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  DOI: 10.1016/j.celrep.2025.115294
  
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sciencedirect.com/science/article/pii/S2211124725000658
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MAIT cells protect against sterile lung injury

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  DOI: 10.1016/j.celrep.2025.115275
  
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sciencedirect.com/science/article/pii/S2211124725000464
Dec 2024
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Mechanism of enhancing chemotherapy efficacy in pancreatic ductal adenocarcinoma with paricalcitol and hydroxychloroquine

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1. scibot 29 Dec 2024
  
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  DOI: 10.1016/j.xcrm.2024.101881
  
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cell.com/cell-reports-medicine/fulltext/S2666-3791(24)00652-9
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Intestinal E. coli-produced yersiniabactin promotes profibrotic macrophages in Crohn’s disease

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1. scibot 21 Dec 2024
  
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  DOI: 10.1016/j.chom.2024.11.012
  
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cell.com/cell-host-microbe/fulltext/S1931-3128(24)00443-8
Nov 2024
52.53.155.43 52.53.155.43

strobl-et-al-2024-jak-stat1-as-therapeutic-target-for-egfr-deficiency-associated-inflammation-and-scarring-alopecia-html.html

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1. scibot 14 Nov 2024
  
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  DOI: 10.1038/s44321-024-00166-3
  
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52.53.155.43/586ba8b525e8da6306112d5dd7635949084313ca/strobl-et-al-2024-jak-stat1-as-therapeutic-target-for-egfr-deficiency-associated-inflammation-and-scarring-alopecia-html.html
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JAK-STAT1 as therapeutic target for EGFR deficiency-associated inflammation and scarring alopecia

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1. scibot 14 Nov 2024
  
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  DOI: 10.1038/s44321-024-00166-3
  
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  DOI: 10.1038/s44321-024-00166-3
  
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embopress.org/doi/10.1038/s44321-024-00166-3
May 2024
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Classical monocyte ontogeny dictates their functions and fates as tissue macrophages

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Apr 2024
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CXCL9/10-engineered dendritic cells promote T cell activation and enhance immune checkpoint blockade for lung cancer

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  DOI: 10.1016/j.xcrm.2024.101479
  
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Mar 2024
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ATF4-SLC7A11-GSH axis mediates the acquisition of immunosuppressive properties by activated CD4+ T cells in low arginine condition

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1. scibot 27 Mar 2024
  
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Feb 2024
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Scarring hair follicle destruction is driven by the collapse of EGFR-protected JAK-STAT1-sensitive stem cell immune privilege

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1. scibot 23 Feb 2024
  
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52.53.155.43/96ec307650875a091f9342a8f5a3978ef308aaef/2023.10.11.561653v1.full-html.html
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Tumor-secreted FGF21 acts as an immune suppressor by rewiring cholesterol metabolism of CD8+T cells

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Jan 2024
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Lymph node and tumor-associated PD-L1+ macrophages antagonize dendritic cell vaccines by suppressing CD8+ T cells

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  DOI: 10.1016/j.xcrm.2023.101377
  
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Characterization of immune populations in the tumor microenvironment of diffuse midline glioma orthotopic mouse models by flow cytometry

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  DOI: 10.1016/j.xpro.2023.102803
  
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Oct 2023
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Uptake of tumor-derived microparticles induces metabolic reprogramming of macrophages in the early metastatic lung

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1. scibot 27 Oct 2023
  
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  DOI: 10.1016/j.celrep.2023.112582
  
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TIM-3 blockade in diffuse intrinsic pontine glioma models promotes tumor regression and antitumor immune memory

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Aug 2023
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Chronic HDM exposure shows time-of-day and sex-based differences in inflammatory response associated with lung circadian clock disruption

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1. scibot 23 Aug 2023
  
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  DOI: 10.1016/j.isci.2023.107580
  
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sciencedirect.com/science/article/pii/S2589004223016577
May 2023
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Homeostatic activation of aryl hydrocarbon receptor by dietary ligands dampens cutaneous allergic responses by controlling Langerhans cells migration

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1. scibot 18 May 2023
  
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  DOI: 10.7554/eLife.86413
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10188110/
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Tumor eradication by hetIL-15 locoregional therapy correlates with an induced intratumoral CD103intCD11b+ dendritic cell population

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  DOI: 10.1016/j.celrep.2023.112501
  
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Bat ASC2 suppresses inflammasomes and ameliorates inflammatory diseases

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1. scibot 12 May 2023
  
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  DOI: 10.1016/j.cell.2023.03.036
  
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sciencedirect.com/science/article/pii/S0092867423003331
Mar 2023
europepmc.org europepmc.org

ILC3s restrict the dissemination of intestinal bacteria to safeguard liver regeneration after surgery

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1. scibot 22 Mar 2023
  
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  DOI: 10.1016/j.celrep.2023.112269
  
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europepmc.org/article/med/36933213
Feb 2023
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A Cre-deleter specific for embryo-derived brain macrophages reveals distinct features of microglia and border macrophages

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1. scibot 16 Feb 2023
  
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  DOI: 10.1016/j.immuni.2023.01.028
  
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sciencedirect.com/science/article/pii/S1074761323000407
Nov 2021
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ILC3s control airway inflammation by limiting T cell responses to allergens and microbes

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1. scibot 24 Nov 2021
  
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A non-classical monocyte-derived macrophage subset provides a splenic replication niche for intracellular Salmonella

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Dysregulation of ILC3s unleashes progression and immunotherapy resistance in colon cancer

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  DOI: 10.1016/j.cell.2021.07.029
  
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Macrophage and neutrophil death programs differentially confer resistance to tuberculosis

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  DOI: 10.1016/j.immuni.2021.06.009
  
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Repression of endogenous retroviruses prevents antiviral immune response and is required for mammary gland development

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1. scibot 19 May 2021
  
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  DOI: 10.1016/j.stem.2021.04.030
  
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JAK1 Inhibition Blocks Lethal Immune Hypersensitivity in a Mouse Model of Down Syndrome

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  DOI: 10.1016/j.celrep.2020.108407
  
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Modulation of Microglia by Voluntary Exercise or CSF1R Inhibition Prevents Age-Related Loss of Functional Motor Units

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  DOI: 10.1016/j.celrep.2019.10.003
  
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Untitled document

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  DOI: 10.1016/j.celrep.2019.01.104
  
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Nov 2018
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High-Dimensional Analysis Delineates Myeloid and Lymphoid Compartment Remodeling during Successful Immune-Checkpoint Cancer Therapy

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Extrathymically Generated Regulatory T Cells Establish a Niche for Intestinal Border-Dwelling Bacteria and Affect Physiologic Metabolite Balance

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