21 Matching Annotations
  1. Last 7 days
  2. www.cell.com www.cell.com
    The PP2A regulatory subunit PPP2R2A controls NAD+ biosynthesis to regulate T cell subset differentiation in systemic autoimmunity
    1
    1. scibot 18 Jul 2024
      RRID:AB_2572318

      DOI: 10.1016/j.celrep.2024.114379

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    cell.com/cell-reports/abstract/S2211-1247(24)00707-1
  3. Jul 2024
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    YZL-51N functions as a selective inhibitor of SIRT7 by NAD+ competition to impede DNA damage repair
    1
    1. scibot 01 Jul 2024
      RRID:AB_2572318

      DOI: 10.1016/j.isci.2024.110014

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    ncbi.nlm.nih.gov/pmc/articles/PMC11214487/
  5. Jan 2024
  6. www.sciencedirect.com www.sciencedirect.com
    PARP5A and RNF146 phase separation restrains RIPK1-dependent necroptosis
    1
    1. scibot 25 Jan 2024
      RRID:AB_2572318

      DOI: 10.1016/j.molcel.2023.12.041

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    sciencedirect.com/science/article/pii/S1097276523011218
  7. Sep 2023
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Bifunctional PARP-HDAC Inhibitor with Activity in Ewing Sarcoma
    1
    1. scibot 07 Sep 2023
      RRID:AB_2572318

      DOI: 10.1158/1078-0432.CCR-22-3897

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    ncbi.nlm.nih.gov/pmc/articles/PMC10472104/
  9. Aug 2023
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Increased SIRT3 combined with PARP inhibition rescues motor function of SBMA mice
    1
    1. scibot 10 Aug 2023
      RRID:AB_2572318

      DOI: 10.1016/j.isci.2023.107375

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    ncbi.nlm.nih.gov/pmc/articles/PMC10433013/
  11. Jul 2023
  12. www.biorxiv.org www.biorxiv.org
    Histone H1.2 Dependent Translocation of Poly (ADP-ribose) Initiates Parthanatos
    1
    1. scibot 07 Jul 2023
      RRID:AB_2572318

      DOI: 10.1101/2023.06.18.545460

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    biorxiv.org/content/10.1101/2023.06.18.545460v3
  13. May 2023
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Repurposing ceritinib induces DNA damage and enhances PARP inhibitor responses in high-grade serous ovarian carcinoma
    1
    1. scibot 05 May 2023
      RRID:AB_2572318

      DOI: 10.1158/0008-5472.CAN-21-0732

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    ncbi.nlm.nih.gov/pmc/articles/PMC8770599/
  15. Jan 2023
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dynamics of endogenous PARP1 and PARP2 during DNA damage revealed by live-cell single-molecule imaging
    1
    1. scibot 06 Jan 2023
      RRID:AB_2572318

      DOI: 10.1016/j.isci.2022.105779

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    ncbi.nlm.nih.gov/pmc/articles/PMC9804145/
  17. Dec 2022
  18. www.sciencedirect.com www.sciencedirect.com
    The ADP-ribose hydrolase NUDT5 is important for DNA repair
    1
    1. scibot 24 Dec 2022
      RRID:AB_2572318

      DOI: 10.1016/j.celrep.2022.111866

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    sciencedirect.com/science/article/pii/S2211124722017624
  19. Oct 2022
  20. www.sciencedirect.com www.sciencedirect.com
    PARP-inhibition reprograms macrophages toward an anti-tumor phenotype
    1
    1. scibot 13 Oct 2022
      RRID:AB_2572318

      DOI: 10.1016/j.celrep.2022.111462

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    sciencedirect.com/science/article/pii/S2211124722013079
  21. Aug 2022
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PARP1 inhibition enhances reactive oxygen species on gut microbiota
    1
    1. scibot 24 Aug 2022
      RRID:AB_2572318

      DOI: 10.1002/jcp.30861

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    ncbi.nlm.nih.gov/pmc/articles/PMC9805012/
  23. May 2022
  24. www.sciencedirect.com www.sciencedirect.com
    A PARylation-phosphorylation cascade promotes TOPBP1 loading and RPA-RAD51 exchange in homologous recombination
    1
    1. scibot 25 May 2022
      RRID:AB_2572318

      DOI: 10.1016/j.molcel.2022.04.031

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    sciencedirect.com/science/article/pii/S109727652200394X
  25. www.sciencedirect.com www.sciencedirect.com
    The lactate-NAD+ axis activates cancer-associated fibroblasts by downregulating p62
    1
    1. scibot 11 May 2022
      RRID:AB_2572318

      DOI: 10.1016/j.celrep.2022.110792

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    sciencedirect.com/science/article/pii/S2211124722005599
  26. Oct 2021
  27. www.sciencedirect.com www.sciencedirect.com
    PARP1-mediated PARylation activity is essential for oligodendroglial differentiation and CNS myelination
    1
    1. scibot 06 Oct 2021
      RRID:AB_2572318

      DOI: 10.1016/j.celrep.2021.109695

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    sciencedirect.com/science/article/pii/S2211124721011426
  28. Jul 2021
  29. www.cell.com www.cell.com
    Replication gaps are a key determinant of PARP inhibitor synthetic lethality with BRCA deficiency
    1
    1. scibot 03 Jul 2021
      RRID:AB_2572318

      DOI: 10.1016/j.molcel.2021.06.011

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    cell.com/molecular-cell/fulltext/S1097-2765(21)00458-5
  30. May 2021
  31. www.sciencedirect.com www.sciencedirect.com
    Epigenetic Regulation of DNA Repair Pathway Choice by MacroH2A1 Splice Variants Ensures Genome Stability
    1
    1. scibot 07 May 2021
      RRID:AB_2572318

      DOI: 10.1016/j.molcel.2020.06.028

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    sciencedirect.com/science/article/pii/S1097276520304305
  32. Sep 2020
  33. elifesciences.org elifesciences.org
    PARP1 inhibitors trigger innate immunity via PARP1 trapping-induced DNA damage response
    1
    1. scibot 16 Sep 2020
      RRID:AB_2572318

      DOI: 10.7554/eLife.60637

      Resource: (Trevigen Cat# 4335-MC-100, RRID:AB_2572318)

      Curator: @evieth

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      RRIDCUR:Validated RRID:AB_2572318
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    elifesciences.org/articles/60637
  34. Jan 2020
  35. www.sciencedirect.com www.sciencedirect.com
    Poly(ADP-Ribose) Polymerase 2 Recruits Replication Protein A to Sites of LINE-1 Integration to Facilitate Retrotransposition
    1
    1. scibot 13 Jan 2020
      RRID:AB_2572318

      DOI: 10.1016/j.molcel.2019.07.018

      Resource: (Trevigen Cat# 4335-MC-100, RRID:AB_2572318)

      Curator: @ethanbadger

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      RRID:AB_2572318 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1097276519305489
  36. www.sciencedirect.com www.sciencedirect.com
    Acquired Resistance of EGFR-Mutated Lung Cancer to Tyrosine Kinase Inhibitor Treatment Promotes PARP Inhibitor Sensitivity
    1
    1. scibot 13 Jan 2020
      RRID:AB_2572318

      DOI: 10.1016/j.celrep.2019.05.058

      Resource: (Trevigen Cat# 4335-MC-100, RRID:AB_2572318)

      Curator: @ethanbadger

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      RRID:AB_2572318 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S2211124719306874
  37. Nov 2017
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sam68/KHDRBS1-dependent NF-κB activation confers radioprotection to the colon epithelium in γ-irradiated mice
    1
    1. scibot 08 Nov 2017
      AB_2572318

      Curator: @gabimpine

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    ncbi.nlm.nih.gov/pmc/articles/PMC5214542/
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of Poly-ADP-Ribosylation Fails to Increase Axonal Regeneration or Improve Functional Recovery after Adult Mammalian CNS Injury
    1
    1. scibot 08 Nov 2017
      AB_2572318

      Curator: @gabimpine

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      (Trevigen Cat# 4335-MC-100, RRID:AB_2572318)

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    ncbi.nlm.nih.gov/pmc/articles/PMC5187389/