Hypothesis

23 Matching Annotations

Last 7 days
www.sciencedirect.com www.sciencedirect.com

Targeted protein degradation via chimeric antigen receptor (CAR)-mediated antigen endocytosis in T cells

1
1. scibot 22 May 2026
  
  in Public
  
  RRID:AB_2573483
  
  DOI: 10.1016/j.hlife.2026.05.003
  
  Resource: (Thermo Fisher Scientific Cat# 25-5870-82, RRID:AB_2573483)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2573483
  
  What is this?
  
  RRID:AB_2573483
Visit annotations in context

Tags

RRID:AB_2573483

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2949928326000313
Apr 2026
www.sciencedirect.com www.sciencedirect.com

Krüppel-like factor 2 programs early exhausted T cell states and restrains antiviral immunity

1
1. scibot 29 Apr 2026
  
  in Public
  
  RRID:AB_2573483
  
  DOI: 10.1016/j.immuni.2026.03.029
  
  Resource: (Thermo Fisher Scientific Cat# 25-5870-82, RRID:AB_2573483)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2573483
  
  What is this?
  
  RRID:AB_2573483
Visit annotations in context

Tags

RRID:AB_2573483

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1074761326001408
Aug 2025
www.sciencedirect.com www.sciencedirect.com

An age-related decrease in leptin contributes to CD8+ T cell aging in the tumor microenvironment

1
1. scibot 26 Aug 2025
  
  in Public
  
  RRID:AB_2573483
  
  DOI: 10.1016/j.xcrm.2025.102310
  
  Resource: (Thermo Fisher Scientific Cat# 25-5870-82, RRID:AB_2573483)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2573483
  
  What is this?
  
  RRID:AB_2573483
Visit annotations in context

Tags

RRID:AB_2573483

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2666379125003830
www.sciencedirect.com www.sciencedirect.com

Engineered T cells stimulate dendritic cell recruitment and antigen spreading for potent anti-tumor immunity

1
1. scibot 26 Aug 2025
  
  in Public
  
  RRID:AB_2573483
  
  DOI: 10.1016/j.xcrm.2025.102307
  
  Resource: (Thermo Fisher Scientific Cat# 25-5870-82, RRID:AB_2573483)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2573483
  
  What is this?
  
  RRID:AB_2573483
Visit annotations in context

Tags

RRID:AB_2573483

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2666379125003805
www.sciencedirect.com www.sciencedirect.com

Succinate preserves CD8+ T cell fitness to augment antitumor immunity

1
1. scibot 15 Aug 2025
  
  in Public
  
  RRID:AB_2573483
  
  DOI: 10.1016/j.immuni.2025.07.017
  
  Resource: (Thermo Fisher Scientific Cat# 25-5870-82, RRID:AB_2573483)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2573483
  
  What is this?
  
  RRID:AB_2573483
Visit annotations in context

Tags

RRID:AB_2573483

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1074761325003267
Jul 2025
www.sciencedirect.com www.sciencedirect.com

Mutant p53 exploits enhancers to elevate immunosuppressive chemokine expression and impair immune checkpoint inhibitors in pancreatic cancer

1
1. scibot 01 Jul 2025
  
  in Public
  
  RRID:AB_2573483
  
  DOI: 10.1016/j.immuni.2025.06.005
  
  Resource: (Thermo Fisher Scientific Cat# 25-5870-82, RRID:AB_2573483)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2573483
  
  What is this?
  
  RRID:AB_2573483
Visit annotations in context

Tags

RRID:AB_2573483

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1074761325002742
Feb 2025
www.sciencedirect.com www.sciencedirect.com

Potentiating anti-tumor immunity by re-engaging immune synapse molecules

1
1. scibot 25 Feb 2025
  
  in Public
  
  RRID:AB_2573483
  
  DOI: 10.1016/j.xcrm.2025.101975
  
  Resource: (Thermo Fisher Scientific Cat# 25-5870-82, RRID:AB_2573483)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2573483
  
  What is this?
  
  RRID:AB_2573483
Visit annotations in context

Tags

RRID:AB_2573483

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2666379125000485
Nov 2024
www.sciencedirect.com www.sciencedirect.com

Fibroblastic reticular cells generate protective intratumoral T cell environments in lung cancer

1
1. scibot 24 Nov 2024
  
  in Public
  
  RRID:AB_2573483
  
  DOI: 10.1016/j.cell.2024.10.042
  
  Resource: (Thermo Fisher Scientific Cat# 25-5870-82, RRID:AB_2573483)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2573483
  
  What is this?
  
  RRID:AB_2573483
Visit annotations in context

Tags

RRID:AB_2573483

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0092867424012595
Sep 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Mutant p53 Exploits Enhancers to Elevate Immunosuppressive Chemokine Expression and Impair Immune Checkpoint Inhibitors in Pancreatic Cancer

1
1. scibot 27 Sep 2024
  
  in Public
  
  AB_2573483
  
  DOI: 10.1101/2024.08.28.609802
  
  Resource: (Thermo Fisher Scientific Cat# 25-5870-82, RRID:AB_2573483)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2573483
  
  What is this?
  
  RRID:AB_2573483
Visit annotations in context

Tags

RRID:AB_2573483

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC11383995/
Jul 2024
www.cell.com www.cell.com

Proteobacteria impair anti-tumor immunity in the omentum by consuming arginine

1
1. scibot 18 Jul 2024
  
  in Public
  
  AB_2573483
  
  DOI: 10.1016/j.chom.2024.06.003
  
  Resource: (Thermo Fisher Scientific Cat# 25-5870-82, RRID:AB_2573483)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2573483
  
  What is this?
  
  RRID:AB_2573483
Visit annotations in context

Tags

RRID:AB_2573483

Annotators

scibot

URL

cell.com/cell-host-microbe/abstract/S1931-3128(24)00197-5
Jun 2024
www.nature.com www.nature.com

A single infusion of engineered long-lived and multifunctional T cells confers durable remission of asthma in mice

1
1. scibot 06 Jun 2024
  
  in Public
  
  RRID:AB_2573483
  
  DOI: 10.1038/s41590-024-01834-9
  
  Resource: (Thermo Fisher Scientific Cat# 25-5870-82, RRID:AB_2573483)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2573483
  
  What is this?
  
  RRID:AB_2573483
Visit annotations in context

Tags

RRID:AB_2573483

Annotators

scibot

URL

nature.com/articles/s41590-024-01834-9
May 2024
www.sciencedirect.com www.sciencedirect.com

Osr2 functions as a biomechanical checkpoint to aggravate CD8+ T cell exhaustion in tumor

1
1. scibot 14 May 2024
  
  in Public
  
  RRID:AB_2573483
  
  DOI: 10.1016/j.cell.2024.04.023
  
  Resource: (Thermo Fisher Scientific Cat# 25-5870-82, RRID:AB_2573483)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2573483
  
  What is this?
  
  RRID:AB_2573483
Visit annotations in context

Tags

RRID:AB_2573483

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0092867424004483
Jan 2024
www.sciencedirect.com www.sciencedirect.com

Bispecific dendritic-T cell engager potentiates anti-tumor immunity

1
1. scibot 19 Jan 2024
  
  in Public
  
  RRID:AB_2573483
  
  DOI: 10.1016/j.cell.2023.12.011
  
  Resource: (Thermo Fisher Scientific Cat# 25-5870-82, RRID:AB_2573483)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2573483
  
  What is this?
  
  RRID:AB_2573483
Visit annotations in context

Tags

RRID:AB_2573483

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0092867423013430
Nov 2023
www.biorxiv.org www.biorxiv.org

One infusion of engineered long-lasting and multifunctional T cells cures asthma in mice

1
1. scibot 17 Nov 2023
  
  in Public
  
  RRID:AB_2573483
  
  DOI: 10.1101/2023.11.06.565713
  
  Resource: (Thermo Fisher Scientific Cat# 25-5870-82, RRID:AB_2573483)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2573483
  
  What is this?
  
  RRID:AB_2573483
Visit annotations in context

Tags

RRID:AB_2573483

Annotators

scibot

URL

biorxiv.org/content/10.1101/2023.11.06.565713v1
Oct 2023
www.sciencedirect.com www.sciencedirect.com

Dietary fructose-mediated adipocyte metabolism drives antitumor CD8+ T cell responses

1
1. scibot 27 Oct 2023
  
  in Public
  
  RRID:AB_2573483
  
  DOI: 10.1016/j.cmet.2023.09.011
  
  Resource: (Thermo Fisher Scientific Cat# 25-5870-82, RRID:AB_2573483)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2573483
  
  What is this?
  
  RRID:AB_2573483
Visit annotations in context

Tags

RRID:AB_2573483

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1550413123003674
Jul 2023
www.sciencedirect.com www.sciencedirect.com

TCR-independent CD137 (4-1BB) signaling promotes CD8+-exhausted T cell proliferation and terminal differentiation

1
1. scibot 01 Jul 2023
  
  in Public
  
  RRID:AB_2573483
  
  DOI: 10.1016/j.immuni.2023.06.007
  
  Resource: (Thermo Fisher Scientific Cat# 25-5870-82, RRID:AB_2573483)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2573483
  
  What is this?
  
  RRID:AB_2573483
Visit annotations in context

Tags

RRID:AB_2573483

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1074761323002649
May 2023
www.sciencedirect.com www.sciencedirect.com

Proteomics of immune cells from liver tumors reveals immunotherapy targets

1
1. scibot 31 May 2023
  
  in Public
  
  RRID:AB_2573483
  
  DOI: 10.1016/j.xgen.2023.100331
  
  Resource: (Thermo Fisher Scientific Cat# 25-5870-82, RRID:AB_2573483)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2573483
  
  What is this?
  
  RRID:AB_2573483
Visit annotations in context

Tags

RRID:AB_2573483

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2666979X2300099X
Feb 2023
www.sciencedirect.com www.sciencedirect.com

XCR1+ DCs are critical for T cell-mediated immunotherapy of chronic viral infections

1
1. scibot 16 Feb 2023
  
  in Public
  
  RRID:AB_2573483
  
  DOI: 10.1016/j.celrep.2023.112123
  
  Resource: (Thermo Fisher Scientific Cat# 25-5870-82, RRID:AB_2573483)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2573483
  
  What is this?
  
  RRID:AB_2573483
Visit annotations in context

Tags

RRID:AB_2573483

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124723001341
Nov 2022
www.sciencedirect.com www.sciencedirect.com

Mobilizing phospholipids on tumor plasma membrane implicates phosphatidylserine externalization blockade for cancer immunotherapy

1
1. scibot 03 Nov 2022
  
  in Public
  
  RRID:AB_2573483
  
  DOI: 10.1016/j.celrep.2022.111582
  
  Resource: (Thermo Fisher Scientific Cat# 25-5870-82, RRID:AB_2573483)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2573483
  
  What is this?
  
  RRID:AB_2573483
Visit annotations in context

Tags

RRID:AB_2573483

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124722014474
May 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Functional assessment of the cell-autonomous role of NADase CD38 in regulating CD8+ T cell exhaustion

1
1. scibot 21 May 2022
  
  in Public
  
  RRID:AB_2573483
  
  DOI: 10.1016/j.isci.2022.104347
  
  Resource: (Thermo Fisher Scientific Cat# 25-5870-82, RRID:AB_2573483)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2573483
  
  What is this?
  
  RRID:AB_2573483
Visit annotations in context

Tags

RRID:AB_2573483

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC9117873/
Dec 2021
www.sciencedirect.com www.sciencedirect.com

Genome-wide fitness gene identification reveals Roquin as a potent suppressor of CD8 T cell expansion and anti-tumor immunity

1
1. scibot 08 Dec 2021
  
  in Public
  
  RRID:AB_2573483
  
  DOI: 10.1016/j.celrep.2021.110083
  
  Resource: (Thermo Fisher Scientific Cat# 25-5870-82, RRID:AB_2573483)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2573483
  
  What is this?
  
  RRID:AB_2573483
Visit annotations in context

Tags

RRID:AB_2573483

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124721015746
May 2021
www.sciencedirect.com www.sciencedirect.com

Eomes-Dependent Loss of the Co-activating Receptor CD226 Restrains CD8+ T Cell Anti-tumor Functions and Limits the Efficacy of Cancer Immunotherapy

1
1. scibot 07 May 2021
  
  in Public
  
  RRID:AB_2573483
  
  DOI: 10.1016/j.immuni.2020.09.006
  
  Resource: (Thermo Fisher Scientific Cat# 25-5870-82, RRID:AB_2573483)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2573483
  
  What is this?
  
  RRID:AB_2573483
Visit annotations in context

Tags

RRID:AB_2573483

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1074761320304003
Apr 2021
link.springer.com link.springer.com

Selected Clostridia Strains from The Human Microbiota and their Metabolite, Butyrate, Improve Experimental Autoimmune Encephalomyelitis

1
1. scibot 13 Apr 2021
  
  in Public
  
  RRID:AB_2573483
  
  DOI: 10.1007/s13311-021-01016-7
  
  Resource: (Thermo Fisher Scientific Cat# 25-5870-82, RRID:AB_2573483)
  
  Curator: @evieth
  
  SciCrunch record: RRID:AB_2573483
  
  What is this?
  
  RRIDCUR:Validated RRID:AB_2573483
Visit annotations in context

Tags

RRID:AB_2573483

RRIDCUR:Validated

Annotators

scibot

URL

link.springer.com/article/10.1007/s13311-021-01016-7