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Aug 2026
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The ADAP-TRIM21-ZEB2 axis regulates CD8+ T cell effector expansion and central memory-like differentiation

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1. scibot 03 Aug 2026
  
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  DOI: 10.1016/j.isci.2026.117016
  
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sciencedirect.com/science/article/pii/S2589004226023941
Jul 2026
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B cell-derived type I interferon sustains T cell functionality upon strong TCR stimulation during chronic infection

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1. scibot 06 Jul 2026
  
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  DOI: 10.1016/j.immuni.2026.06.003
  
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sciencedirect.com/science/article/pii/S1074761326002542
Jun 2026
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Stem-like precursors of exhausted Th cells upheld by a Tox-Myb-Eomes transcriptional hierarchy propagate Th cell responses in chronic infection

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1. scibot 26 Jun 2026
  
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  DOI: 10.1016/j.immuni.2026.06.001
  
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sciencedirect.com/science/article/pii/S1074761326002311
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TCR Signal Strength and Eomes Coordinate CD8+ T Cell Fate and Antitumor Immunity in Hepatocellular Carcinoma

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1. scibot 25 Jun 2026
  
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  DOI: 10.64898/2026.02.10.705135
  
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biorxiv.org/content/10.64898/2026.02.10.705135v1
Apr 2026
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IFNγ-induced PD-L1+MHC II+ macrophages and Tim-3+ tumor-reactive CD8+ T cells predict a response to anti-PD-1 therapy in tumor-bearing mice

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1. scibot 23 Apr 2026
  
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  DOI: 10.1158/2326-6066.CIR-24-0835
  
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aacrjournals.org/cancerimmunolres/article/13/12/2004/768334/IFN-Induced-PD-L1-MHCII-Macrophages-and-Tim-3
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Upregulation of TNFR2 Precedes TOX Expression by Exhausted T cells and Restricts Antitumor and Antiviral Immunity

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1. scibot 09 Apr 2026
  
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  DOI: 10.1158/1078-0432.CCR-24-3455
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13056295/
54.241.53.176 54.241.53.176

Age-dependent tumor-immune interactions underlie immunotherapy response in pediatric cancer

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1. scibot 09 Apr 2026
  
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  DOI: 10.1101/2025.07.16.663652
  
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54.241.53.176/768db83f320dea5b389687f4152c3097d0ac27c7/2025.07.16.663652.full-html.html
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Acute and chronic infections drive distinct trajectories in human memory CD4+ T cell formation

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1. scibot 02 Apr 2026
  
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  DOI: 10.1016/j.immuni.2026.03.008
  
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sciencedirect.com/science/article/pii/S1074761326001196
Mar 2026
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NF-κB-activated fibroblasts orchestrate inflammaging and emergence of pro-inflammatory granzyme K+ T cells

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1. scibot 31 Mar 2026
  
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  DOI: 10.1016/j.immuni.2026.02.016
  
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sciencedirect.com/science/article/pii/S1074761326000865
Feb 2026
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Effector differentiation by stem-like intraepithelial γδ T cells is required for host defense against infection

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1. scibot 26 Feb 2026
  
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  DOI: 10.1016/j.immuni.2026.01.006
  
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sciencedirect.com/science/article/pii/S1074761326000270
Dec 2025
www.sciencedirect.com:5037 www.sciencedirect.com:5037

An innovative engineered IL-10 monomer strengthens T cell-mediated anti-tumor responses through anti-PD-1 cis-delivery

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1. scibot 17 Dec 2025
  
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  DOI: 10.1016/j.xcrm.2025.102515
  
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sciencedirect.com:5037/science/article/pii/S2666379125005889
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The transcription factor Helios restrains the anti-tumor capacity of CD8+ T cells

1
1. scibot 13 Dec 2025
  
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  DOI: 10.1016/j.celrep.2025.116680
  
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sciencedirect.com:5037/science/article/pii/S2211124725014524
Oct 2025
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The transcriptional repressor BLIMP1 enforces TCF-1-dependent and -independent restriction of the memory fate of CD8+ T cells

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1. scibot 08 Oct 2025
  
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  DOI: 10.1016/j.immuni.2025.09.008
  
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sciencedirect.com/science/article/pii/S1074761325004194
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Eomesodermin+ CD4+ T cells are critical for curative immunotherapy outcomes

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1. scibot 04 Oct 2025
  
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  DOI: 10.1016/j.immuni.2025.09.004
  
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sciencedirect.com/science/article/pii/S1074761325004157
Aug 2025
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Lymphoma accelerates T cell and tissue aging

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1. scibot 26 Aug 2025
  
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  DOI: 10.1016/j.ccell.2025.07.023
  
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sciencedirect.com/science/article/pii/S1535610825003290
May 2025
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Bone metastases diminish extraosseous response to checkpoint blockade immunotherapy through osteopontin-producing osteoclasts

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1. scibot 16 May 2025
  
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  DOI: 10.1016/j.ccell.2025.03.036
  
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sciencedirect.com/science/article/pii/S1535610825001370
Mar 2025
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Restoration of LAT activity improves CAR T cell sensitivity and persistence in response to antigen-low acute lymphoblastic leukemia

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1. scibot 11 Mar 2025
  
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  DOI: 10.1016/j.ccell.2025.02.008
  
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sciencedirect.com/science/article/pii/S1535610825000601
Feb 2025
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Tumor cell–intrinsic Piezo2 drives radioresistance by impairing CD8+ T cell stemness maintenance

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1. scibot 26 Feb 2025
  
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  DOI: 10.1084/jem.20231486
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11338319/
Jan 2025
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Redirecting glucose flux during in vitro expansion generates epigenetically and metabolically superior T cells for cancer immunotherapy

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1. scibot 30 Jan 2025
  
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  DOI: 10.1016/j.cmet.2024.12.007
  
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sciencedirect.com/science/article/pii/S1550413124004893
Dec 2024
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Antigen presentation by tumor-associated macrophages drives T cells from a progenitor exhaustion state to terminal exhaustion

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1. scibot 28 Dec 2024
  
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  DOI: 10.1016/j.immuni.2024.11.026
  
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Nov 2024
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A subset of neutrophils activates anti-tumor immunity and inhibits non-small-cell lung cancer progression

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1. scibot 11 Nov 2024
  
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  DOI: 10.1016/j.devcel.2024.10.010
  
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sciencedirect.com/science/article/pii/S1534580724006294
Sep 2024
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The transcription regulator ID3 maintains tumor-specific memory CD8+ T cells in draining lymph nodes during tumorigenesis

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1. scibot 04 Sep 2024
  
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  DOI: 10.1016/j.celrep.2024.114690
  
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sciencedirect.com/science/article/pii/S2211124724010416
Jun 2024
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Therapeutic potential of co-signaling receptor modulation in hepatitis B

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1. scibot 21 Jun 2024
  
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  DOI: 10.1016/j.cell.2024.05.038
  
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sciencedirect.com/science/article/pii/S0092867424005828
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NR4A1 transcriptionally regulates the differentiation of stem-like CD8+ T cells in the tumor microenvironment

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1. scibot 04 Jun 2024
  
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  DOI: 10.1016/j.celrep.2024.114301
  
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May 2024
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Metabolic regulator LKB1 controls adipose tissue ILC2 PD-1 expression and mitochondrial homeostasis to prevent insulin resistance

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1. scibot 21 May 2024
  
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  DOI: 10.1016/j.immuni.2024.04.024
  
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Mar 2024
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Bile acids modified by the intestinal microbiota promote colorectal cancer growth by suppressing CD8+ T cell effector functions

2
1. scibot 13 Mar 2024
  
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  DOI: 10.1016/j.immuni.2024.02.014
  
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  DOI: 10.1016/j.immuni.2024.02.014
  
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sciencedirect.com/science/article/pii/S1074761324000906
Feb 2024
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Cell-intrinsic PD-L1 ablation sustains effector CD8+ T cell responses and promotes antitumor T cell therapy

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1. scibot 02 Feb 2024
  
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  DOI: 10.1016/j.celrep.2024.113712
  
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Oct 2023
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Antigen presentation by tumor-associated macrophages mediates progenitor to terminal exhaustion transition in GBM and other solid tumors

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1. scibot 14 Oct 2023
  
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  DOI: 10.1101/2023.08.11.553007
  
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  DOI: 10.1101/2023.08.11.553007
  
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52.53.155.43/7eb24570d443d458f8fd7700f91970ed0d945838/2023.08.11.553007v1.full-html.html
Aug 2023
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The two enantiomers of 2-hydroxyglutarate differentially regulate cytotoxic T cell function

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1. scibot 25 Aug 2023
  
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  DOI: 10.1016/j.celrep.2023.113013
  
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sciencedirect.com/science/article/pii/S2211124723010240
52.53.155.43 52.53.155.43

Homeostatic PD-1 signaling restrains EOMES-dependent oligoclonal expansion of liver-resident CD8 T cells

2
1. scibot 12 Aug 2023
  
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  DOI: 10.1016/j.celrep.2023.112876
  
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2. scibot 10 Aug 2023
  
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  DOI: 10.1016/j.celrep.2023.112876
  
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52.53.155.43/7d9bf3333b9425342ca4204697d643342388db9f/PIIS2211124723008872-html.html
Jul 2023
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A distinct stimulatory cDC1 subpopulation amplifies CD8+ T cell responses in tumors for protective anti-cancer immunity

1
1. scibot 14 Jul 2023
  
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  DOI: 10.1016/j.ccell.2023.06.008
  
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sciencedirect.com/science/article/pii/S1535610823002180
Apr 2023
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PSGL-1 attenuates early TCR signaling to suppress CD8+ T cell progenitor differentiation and elicit terminal CD8+ T cell exhaustion

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1. scibot 29 Apr 2023
  
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  RRID:AB_2574265
  
  DOI: 10.1016/j.celrep.2023.112436
  
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sciencedirect.com/science/article/pii/S2211124723004473
Jan 2023
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P2RX7 enhances tumor control by CD8+ T cells in adoptive cell therapy

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1. scibot 06 Jan 2023
  
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  DOI: 10.1158/2326-6066.CIR-21-0691
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9250641/
Oct 2022
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The primordial differentiation of tumor-specific memory CD8+ T cells as bona fide responders to PD-1/PD-L1 blockade in draining lymph nodes

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1. scibot 09 Oct 2022
  
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  DOI: 10.1016/j.cell.2022.09.020
  
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sciencedirect.com/science/article/pii/S0092867422011928
Jun 2022
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BCL6-dependent TCF-1+ progenitor cells maintain effector and helper CD4+ T cell responses to persistent antigen

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1. scibot 03 Jun 2022
  
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  DOI: 10.1016/j.immuni.2022.05.003
  
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sciencedirect.com/science/article/pii/S1074761322002230
Apr 2022
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Ovarian cancer immunogenicity is governed by a narrow subset of progenitor tissue-resident memory T cells

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1. scibot 15 Apr 2022
  
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  DOI: 10.1016/j.ccell.2022.03.008
  
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  Curator: @sophiastull
  
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2. scibot 15 Apr 2022
  
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  DOI: 10.1016/j.ccell.2022.03.008
  
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sciencedirect.com/science/article/pii/S1535610822001234
Sep 2021
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PD-1+ Tcf1+ CD8+ T cells from established chronic infection can form memory while retaining a stableimprint of persistent antigen exposure

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1. scibot 08 Sep 2021
  
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  DOI: 10.1016/j.celrep.2021.109672
  
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  Curator: @Naa003
  
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sciencedirect.com/science/article/pii/S2211124721011165
Jun 2021
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NLRP3 Regulates IL-4 Expression in TOX+ CD4+ T Cells of Cutaneous T Cell Lymphoma to Potentially Promote Disease Progression

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1. scibot 26 Jun 2021
  
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  DOI: 10.3389/fimmu.2021.668369
  
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frontiersin.org/article/10.3389/fimmu.2021.668369/full