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Nov 2026
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UFSP2 constitutes a targetable vulnerability via deUFMylation-dependent activation of AKT oncogenic signaling

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sciencedirect.com/science/article/pii/S2211124726012933
Sep 2026
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A lysis-derived PMSF and orthovanadate oxidant defines a distinct cysteine-engagement profile

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sciencedirect.com/science/article/pii/S2451945626002928
Oct 2025
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Limited activation interdependence and differing patterns of the in vivo effects of IKK1 and IKK2 downstream of NIK

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sciencedirect.com/science/article/pii/S2211124725011751
Sep 2025
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Vps8 overexpression inhibits HOPS-dependent trafficking routes by outcompeting Vps41/Lt

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pmc.ncbi.nlm.nih.gov/articles/PMC6592680/
May 2025
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Cryptosporidium modifies intestinal microvilli through an exported virulence factor

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sciencedirect.com/science/article/pii/S1931312825001349
Apr 2025
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Hypoxia-induced PRMT1 methylates HIF2β to promote breast tumorigenesis via enhancing glycolytic gene transcription

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sciencedirect.com/science/article/pii/S221112472500258X
Mar 2025
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Macrophage-specific PHGDH protects against MAFLD by suppressing TAK1

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sciencedirect.com/science/article/pii/S2211124725001974
Dec 2024
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Formyl-methionine-mediated eukaryotic ribosome quality control pathway for cold adaptation

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cell.com/molecular-cell/abstract/S1097-2765(24)00990-0
Sep 2024
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PICKLE-mediated nucleosome condensing drives H3K27me3 spreading for the inheritance of Polycomb memory during differentiation

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Aug 2024
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Sugar-mediated non-canonical ubiquitination impairs Nrf1/NFE2L1 activation

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sciencedirect.com/science/article/pii/S1097276524005896
Jul 2024
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Discovery of a peptide proteolysis-targeting chimera (PROTAC) drug of p300 for prostate cancer therapy

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ncbi.nlm.nih.gov/pmc/articles/PMC11261775/
May 2024
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Specificity profiling of deubiquitylases against endogenously generated ubiquitin-protein conjugates

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sciencedirect.com/science/article/pii/S2451945624001806
Apr 2024
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Unraveling the landscapes and regulation of scanning, leaky scanning, and 48S initiation complex conformations

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Mar 2024
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Discovery of SQSTM1/p62-dependent P-bodies that regulate the NLRP3 inflammasome

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sciencedirect.com/science/article/pii/S2211124724002638
Nov 2023
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Targeting PRMT1-mediated SRSF1 methylation to suppress oncogenic exon inclusion events and breast tumorigenesis

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sciencedirect.com/science/article/pii/S2211124723013979
Sep 2023
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PARP1 inhibition protects mice against Japanese encephalitis virus infection

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  DOI: 10.1016/j.celrep.2023.113103
  
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sciencedirect.com/science/article/pii/S2211124723011142
Aug 2023
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NFYC-37 promotes tumor growth by activating the mevalonate pathway in bladder cancer

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1. scibot 17 Aug 2023
  
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  DOI: 10.1016/j.celrep.2023.112963
  
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2. scibot 10 Aug 2023
  
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52.53.155.43/eb7aace05cf7a189f4453bfbeb3bcf344412f769/mmc4-html.html
May 2023
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Antagonistic interactions among structured domains in the multivalent Bicc1-ANKS3-ANKS6 protein network govern phase transitioning of target mRNAs

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sciencedirect.com/science/article/pii/S258900422300932X
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ERK and USP5 govern PD-1 homeostasis via deubiquitination to modulate tumor immunotherapy

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  DOI: 10.1038/s41467-023-38605-3
  
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nature.com/articles/s41467-023-38605-3
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MTHFD2 reprograms macrophage polarization by inhibiting PTEN

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Phase separation of HRLP regulates flowering time in Arabidopsis

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  DOI: 10.1126/sciadv.abn5488
  
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science.org/doi/10.1126/sciadv.abn5488
Oct 2022
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An atlas of bacterial two-component systems reveals function and plasticity in signal transduction

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sciencedirect.com/science/article/pii/S2211124722013523
Jul 2022
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Phase separation of HRLP regulates flowering time in Arabidopsis

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ncbi.nlm.nih.gov/pmc/articles/PMC9217094/
Apr 2022
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Recycling of autophagosomal components from autolysosomes by the recycler complex

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  DOI: 10.1038/s41556-022-00861-8
  
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nature.com/articles/s41556-022-00861-8
Jan 2022
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Acetylation-dependent regulation of BRAF oncogenic function

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sciencedirect.com/science/article/pii/S2211124721017629
Nov 2021
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Interplay between protein acetylation and ubiquitination controls MCL1 protein stability

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sciencedirect.com/science/article/pii/S2211124721014674
Oct 2021
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Structural characterization of NrnC identifies unifying features of dinucleotidases

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ncbi.nlm.nih.gov/pmc/articles/PMC8492067/
Aug 2021
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Optimized protocols for ChIP-seq and deletion mutant construction in Pseudomonas syringae

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Multiple regulatory intrinsically disordered motifs control FOXO4 transcription factor binding and function

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Untitled document

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ncbi.nlm.nih.gov/pmc/articles/PMC5780041/
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Untitled document

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  DOI: 10.7554/eLife.39655
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6211827/
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Untitled document

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  DOI: 10.1016/j.devcel.2018.11.035
  
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sciencedirect.com/science/article/pii/S1534580718310189
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  DOI: 10.1016/j.celrep.2018.09.045
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6338448/
Jun 2021
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NADK is activated by oncogenic signaling to sustain pancreatic ductal adenocarcinoma

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  DOI: 10.1016/j.celrep.2021.109238
  
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Translational Repression of G3BP in Cancer and Germ Cells Suppresses Stress Granules and Enhances Stress Tolerance

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Functional interrogation of DNA damage response variants with base editing screens

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Integrated regulatory network in Pseudomonas syringae reveals dynamics of virulence

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Cytomegalovirus restricts ICOSL expression on antigen-presenting cells disabling T cell co-stimulation and contributing to immune evasion

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3D in situ imaging of the female reproductive tract reveals molecular signatures of fertilizing spermatozoa in mice

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Functional Diversification of SRSF Protein Kinase to Control Ubiquitin-Dependent Neurodevelopmental Signaling

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FBXW7 Confers Radiation Survival by Targeting p53 for Degradation

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The Replisome Mediates A-NHEJ Repair of Telomeres Lacking POT1-TPP1 Independently of MRN Function

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PI31 Is an Adaptor Protein for Proteasome Transport in Axons and Required for Synaptic Development

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Vps8 overexpression inhibits HOPS-dependent trafficking routes by outcompeting Vps41/Lt

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STING-Mediated IFI16 Degradation Negatively Controls Type I Interferon Production

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Amyloid-like Assembly Activates a Phosphatase in the Developing Drosophila Embryo

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NPGPx-Mediated Adaptation to Oxidative Stress Protects Motor Neurons from Degeneration in Aging by Directly Modulating O-GlcNAcase

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Adhesive L1CAM-Robo Signaling Aligns Growth Cone F-Actin Dynamics to Promote Axon-Dendrite Fasciculation in C. elegans

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Untitled document

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Untitled document

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Active N6-Methyladenine Demethylation by DMAD Regulates Gene Expression by Coordinating with Polycomb Protein in Neurons

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Assembly of the WHIP-TRIM14-PPP6C Mitochondrial Complex Promotes RIG-I-Mediated Antiviral Signaling

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SHRED Is a Regulatory Cascade that Reprograms Ubr1 Substrate Specificity for Enhanced Protein Quality Control during Stress

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Crystal Structure of Bicc1 SAM Polymer and Mapping of Interactions between the Ciliopathy-Associated Proteins Bicc1, ANKS3, and ANKS6

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The TORC1-Regulated CPA Complex Rewires an RNA Processing Network to Drive Autophagy and Metabolic Reprogramming

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Restoration of Replication Fork Stability in BRCA1- and BRCA2-Deficient Cells by Inactivation of SNF2-Family Fork Remodelers

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NOTCH2 Hajdu-Cheney Mutations Escape SCFFBW7-Dependent Proteolysis to Promote Osteoporosis

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GCL and CUL3 Control the Switch between Cell Lineages by Mediating Localized Degradation of an RTK

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Retrograde Synaptic Inhibition Is Mediated by α-Neurexin Binding to the α2δ Subunits of N-Type Calcium Channels

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Type 2 Diabetes Variants Disrupt Function of SLC16A11 through Two Distinct Mechanisms

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mmc1.pdf

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