132 Matching Annotations
  1. Nov 2024
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting BCL2 with Venetoclax Enhances the Efficacy of the KRASG12D Inhibitor MRTX1133 in Pancreatic Cancer
    1
    1. scibot 08 Nov 2024
      RRID:AB_258167

      DOI: 10.1158/0008-5472.CAN-23-3574

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    pmc.ncbi.nlm.nih.gov/articles/PMC11532783/
  3. Oct 2024
  4. elifesciences.org elifesciences.org
    Inhibitors of the small membrane (M) protein viroporin prevent Zika virus infection
    1
    1. scibot 06 Oct 2024
      RRID:AB_258167

      DOI: 10.7554/eLife.68404

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    elifesciences.org/articles/68404
  5. Sep 2024
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cancer cell stiffening via CoQ10 and UBIAD1 regulates ECM signaling and ferroptosis in breast cancer
    1
    1. scibot 25 Sep 2024
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      DOI: 10.1038/s41467-024-52523-y

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    ncbi.nlm.nih.gov/pmc/articles/PMC11410950/
  7. www.sciencedirect.com www.sciencedirect.com
    Adipose ADM2 ameliorates NAFLD via promotion of ceramide catabolism
    1
    1. scibot 17 Sep 2024
      RRID:AB_258167

      DOI: 10.1016/j.apsb.2024.09.010

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    sciencedirect.com/science/article/pii/S2211383524003733
  8. Aug 2024
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chronic Lithium Treatment Alters NMDA and AMPA Receptor Synaptic Availability and Dendritic Spine Organization in the Rat Hippocampus
    1
    1. scibot 23 Aug 2024
      RRID:AB_258167

      DOI: 10.2174/1570159X21666230913144420

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    ncbi.nlm.nih.gov/pmc/articles/PMC11333793/
  10. www.sciencedirect.com www.sciencedirect.com
    The structure of the Orm2-containing serine palmitoyltransferase complex reveals distinct inhibitory potentials of yeast Orm proteins
    1
    1. scibot 22 Aug 2024
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      DOI: 10.1016/j.celrep.2024.114627

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    sciencedirect.com/science/article/pii/S221112472400977X
  11. www.sciencedirect.com www.sciencedirect.com
    Sigma-1 receptor recruits LC3 mRNA to ER-associated omegasomes to promote localized LC3 translation enabling functional autophagy
    1
    1. scibot 21 Aug 2024
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      DOI: 10.1016/j.celrep.2024.114619

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    sciencedirect.com/science/article/pii/S2211124724009690
  12. Jul 2024
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A methodology to globally assess ectodomain shedding using soluble fractions from the mouse brain
    1
    1. scibot 07 Jul 2024
      RRID:AB_258167

      DOI: 10.3389/fpsyt.2024.1367526

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    ncbi.nlm.nih.gov/pmc/articles/PMC11219901/
  14. Jun 2024
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Exocyst Complex is Required for the Trafficking and Delivery of KCa3.1 to the Basolateral Membrane of Polarized Epithelia
    1
    1. scibot 07 Jun 2024
      RRID:AB_258167

      DOI: 10.1152/ajpcell.00374.2022

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    ncbi.nlm.nih.gov/pmc/articles/PMC10243536/
  16. May 2024
  17. www.sciencedirect.com www.sciencedirect.com
    Autophagy preferentially degrades non-fibrillar polyQ aggregates
    1
    1. scibot 17 May 2024
      RRID:AB_258167

      DOI: 10.1016/j.molcel.2024.04.018

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    sciencedirect.com/science/article/pii/S1097276524003836
  18. www.biorxiv.org www.biorxiv.org
    p75NTR upregulation following perinatal hypoxia leads to deficits in parvalbumin-expressing GABAergic cell maturation, cortical activity and cognitive abilities in adult mice
    1
    1. scibot 03 May 2024
      RRID:AB_258167

      DOI: 10.1101/2024.01.16.574659

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    biorxiv.org/content/10.1101/2024.01.16.574659v1
  19. www.sciencedirect.com www.sciencedirect.com
    A dynamin superfamily-like pseudoenzyme coordinates with MICOS to promote cristae architecture
    1
    1. scibot 01 May 2024
      RRID:AB_258167

      DOI: 10.1016/j.cub.2024.04.028

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    sciencedirect.com/science/article/pii/S0960982224004688
  20. Apr 2024
  21. www.sciencedirect.com www.sciencedirect.com
    Turnover of PPP1R15A mRNA encoding GADD34 controls responsiveness and adaptation to cellular stress
    1
    1. scibot 12 Apr 2024
      RRID:AB_258167

      DOI: 10.1016/j.celrep.2024.114069

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    sciencedirect.com/science/article/pii/S2211124724003978
  22. Feb 2024
  23. www.sciencedirect.com www.sciencedirect.com
    A metabolically controlled contact site between vacuoles and lipid droplets in yeast
    3
    1. scibot 21 Feb 2024
      RRID:AB_258167

      DOI: 10.1016/j.devcel.2024.01.016

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    2. scibot 21 Feb 2024
      RRID:AB_258167

      DOI: 10.1016/j.devcel.2024.01.016

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    3. scibot 21 Feb 2024
      RRID:AB_258167

      DOI: 10.1016/j.devcel.2024.01.016

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    sciencedirect.com/science/article/pii/S1534580724000364
  24. www.sciencedirect.com www.sciencedirect.com
    SIN3A histone deacetylase action counteracts MUS81 to promote stalled fork stability
    1
    1. scibot 13 Feb 2024
      RRID:AB_258167

      DOI: 10.1016/j.celrep.2024.113778

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    sciencedirect.com/science/article/pii/S2211124724001062
  25. Jan 2024
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Riboproteome remodelling during quiescence exit in Saccharomyces cerevisiae
    1
    1. scibot 20 Jan 2024
      RRID:AB_258167

      DOI: 10.1016/j.isci.2023.108727

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    ncbi.nlm.nih.gov/pmc/articles/PMC10792236/
  27. www.sciencedirect.com www.sciencedirect.com
    Conformational transitions and activation of the adhesion receptor CD97
    1
    1. scibot 18 Jan 2024
      RRID:AB_258167

      DOI: 10.1016/j.molcel.2023.12.020

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    sciencedirect.com/science/article/pii/S1097276523010390
  28. Dec 2023
  29. www.sciencedirect.com www.sciencedirect.com
    Multisite phosphorylation dictates selective E2-E3 pairing as revealed by Ubc8/UBE2H-GID/CTLH assemblies
    1
    1. scibot 19 Dec 2023
      RRID:AB_258167

      DOI: 10.1016/j.molcel.2023.11.027

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    sciencedirect.com/science/article/pii/S1097276523009723
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Apolipoprotein E (ApoE) orchestrates adipose tissue inflammation and metabolic disorders through NLRP3 inflammasome
    1
    1. scibot 13 Dec 2023
      RRID:AB_258167

      DOI: 10.1186/s43556-023-00158-8

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    ncbi.nlm.nih.gov/pmc/articles/PMC10703753/
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CerS6-dependent ceramide synthesis in hypothalamic neurons promotes ER/mitochondrial stress and impairs glucose homeostasis in obese mice
    1
    1. scibot 01 Dec 2023
      RRID:AB_258167

      DOI: 10.1038/s41467-023-42595-7

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    ncbi.nlm.nih.gov/pmc/articles/PMC10684560/
  32. Oct 2023
  33. www.sciencedirect.com www.sciencedirect.com
    Cerebral organoids derived from patients with Alzheimer’s disease with PSEN1/2 mutations have defective tissue patterning and altered development
    1
    1. scibot 27 Oct 2023
      RRID:AB_258167

      DOI: 10.1016/j.celrep.2023.113310

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    sciencedirect.com/science/article/pii/S2211124723013220
  34. www.sciencedirect.com www.sciencedirect.com
    Targeting LYPLAL1-mediated cGAS depalmitoylation enhances the response to anti-tumor immunotherapy
    1
    1. scibot 13 Oct 2023
      RRID:AB_258167

      DOI: 10.1016/j.molcel.2023.09.007

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    sciencedirect.com/science/article/pii/S1097276523007025
  35. www.embopress.org www.embopress.org
    Immune–epithelial cell cross-talk enhances antiviral responsiveness to SARS-CoV-2 in children
    1
    1. scibot 13 Oct 2023
      RRID:AB_258167

      DOI: 10.15252/embr.202357912

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    embopress.org/doi/full/10.15252/embr.202357912
  36. www.embopress.org www.embopress.org
    Hypoxia activates SREBP2 through Golgi disassembly in bone marrow-derived monocytes for enhanced tumor growth
    1
    1. scibot 03 Oct 2023
      RRID:AB_258167

      DOI: 10.15252/embj.2023114032

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    embopress.org/doi/10.15252/embj.2023114032
  37. www.sciencedirect.com www.sciencedirect.com
    The senescent secretome drives PLVAP expression in cultured human hepatic endothelial cells to promote monocyte transmigration
    1
    1. scibot 01 Oct 2023
      RRID:AB_258167

      DOI: 10.1016/j.isci.2023.107966

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    sciencedirect.com/science/article/pii/S2589004223020436
  38. Sep 2023
  39. www.sciencedirect.com www.sciencedirect.com
    Signaling protein abundance modulates the strength of the spindle assembly checkpoint
    1
    1. scibot 30 Sep 2023
      RRID:AB_258167

      DOI: 10.1016/j.cub.2023.08.074

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    sciencedirect.com/science/article/pii/S0960982223011545
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lorazepam Stimulates IL6 Production and Is Associated with Poor Survival Outcomes in Pancreatic Cancer
    1
    1. scibot 20 Sep 2023
      RRID:AB_258167

      DOI: 10.1158/1078-0432.CCR-23-0547

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    ncbi.nlm.nih.gov/pmc/articles/PMC10502465/
  41. Jul 2023
  42. www.sciencedirect.com www.sciencedirect.com
    Flat clathrin lattices are linked to metastatic potential in colorectal cancer
    1
    1. scibot 21 Jul 2023
      RRID:AB_258167

      DOI: 10.1016/j.isci.2023.107327

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    sciencedirect.com/science/article/pii/S2589004223014049
  43. www.sciencedirect.com www.sciencedirect.com
    Picolinic acid is a broad-spectrum inhibitor of enveloped virus entry that restricts SARS-CoV-2 and influenza A virus in vivo
    1
    1. scibot 21 Jul 2023
      RRID:AB_258167

      DOI: 10.1016/j.xcrm.2023.101127

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    sciencedirect.com/science/article/pii/S2666379123002550
  44. Jun 2023
  45. www.mdpi.com www.mdpi.com
    Effects of Dietary Oleacein Treatment on Endothelial Dysfunction and Lupus Nephritis in Balb/C Pristane-Induced Mice
    1
    1. scibot 23 Jun 2023
      AB_258167

      DOI: 10.3390/antiox12061303

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    mdpi.com/2076-3921/12/6/1303
  46. www.sciencedirect.com www.sciencedirect.com
    Integrator facilitates RNAPII removal to prevent transcription-replication collisions and genome instability
    1
    1. scibot 09 Jun 2023
      RRID:AB_258167

      DOI: 10.1016/j.molcel.2023.05.015

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    sciencedirect.com/science/article/pii/S1097276523003714
  47. www.embopress.org www.embopress.org
    Human Tim8a, Tim8b and Tim13 are auxiliary assembly factors of mature Complex IV
    1
    1. scibot 06 Jun 2023
      AB_25816

      DOI: 10.15252/embr.202256430

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    embopress.org/doi/10.15252/embr.202256430
  48. Apr 2023
  49. www.sciencedirect.com www.sciencedirect.com
    Interaction between GPR110 (ADGRF1) and tight junction protein occludin implicated in blood-brain barrier permeability
    1
    1. scibot 21 Apr 2023
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      DOI: 10.1016/j.isci.2023.106550

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    sciencedirect.com/science/article/pii/S2589004223006272
  50. www.sciencedirect.com www.sciencedirect.com
    Nutrient-sensing AgRP neurons relay control of liver autophagy during energy deprivation
    1
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      DOI: 10.1016/j.cmet.2023.03.019

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    sciencedirect.com/science/article/pii/S1550413123001249
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    Macrophage CD5L is a target for cancer immunotherapy
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      DOI: 10.1016/j.ebiom.2023.104555

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    sciencedirect.com/science/article/pii/S2352396423001202
  52. www.sciencedirect.com www.sciencedirect.com
    CDK5-PRMT1-WDR24 signaling cascade promotes mTORC1 signaling and tumor growth
    1
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      RRID:AB_258167

      DOI: 10.1016/j.celrep.2023.112316

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    sciencedirect.com/science/article/pii/S2211124723003273
  53. Feb 2023
  54. www.sciencedirect.com www.sciencedirect.com
    DDX47, MeCP2, and other functionally heterogeneous factors protect cells from harmful R loops
    1
    1. scibot 24 Feb 2023
      RRID:AB_258167

      DOI: 10.1016/j.celrep.2023.112148

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    sciencedirect.com/science/article/pii/S2211124723001596
  55. www.nature.com www.nature.com
    The AAA+ chaperone VCP disaggregates Tau fibrils and generates aggregate seeds in a cellular system
    1
    1. scibot 04 Feb 2023
      RRID:AB_258167

      DOI: 10.1038/s41467-023-36058-2

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    nature.com/articles/s41467-023-36058-2
  56. Jan 2023
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SAYSD1 senses UFMylated ribosome to safeguard co-translational protein translocation at the endoplasmic reticulum
    1
    1. scibot 24 Jan 2023
      RRID:AB_258167

      DOI: 10.1016/j.celrep.2023.112028

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  58. Dec 2022
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    Ring domains are essential for GATOR2-dependent mTORC1 activation
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  60. Sep 2022
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    Interaction of RAGE with α-synuclein fibrils mediates inflammatory response of microglia
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    Humanized zebrafish as a tractable tool for in vivo evaluation of pro-myelinating drugs
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  63. Jul 2022
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    A non-transcriptional function of Yap regulates the DNA replication program in Xenopus laevis
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  65. Jun 2022
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    The ER ladder is a unique morphological feature of developing mammalian axons
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  67. May 2022
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    Aspartate metabolism in endothelial cells activates the mTORC1 pathway to initiate translation during angiogenesis
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  69. Apr 2022
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    Structural insights into cooperative DNA recognition by the CCAAT-binding complex and its bZIP transcription factor HapX
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    Regulation of Il6 expression by single CpG methylation in downstream of Il6 transcription initiation site
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    MutSβ regulates G4-associated telomeric R-loops to maintain telomere integrity in ALT cancer cells
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    Functional Assessment of Calcium-Sensing Receptor Variants Confirms Familial Hypocalciuric Hypercalcaemia
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  74. Mar 2022
  75. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Cortical reorganization of the glutamate synapse in the activity-based anorexia rat model: impact on cognition
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    Gα13 loss in Kras/Tp53 mouse model of pancreatic tumorigenesis promotes tumors susceptible to rapamycin
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  79. Feb 2022
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    E3 ligase RNF167 and deubiquitinase STAMBPL1 modulate mTOR and cancer progression
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  81. Jan 2022
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    Stabilization and structure determination of integral membrane proteins by termini restraining
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    Acetylation-dependent regulation of BRAF oncogenic function
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    An antisense transcript transcribed from Irs2 locus contributes to the pathogenesis of hepatic steatosis in insulin resistance
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    High-titer neutralization of Mu and C.1.2 SARS-CoV-2 variants by vaccine-elicited antibodies of previously infected individuals
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  86. Dec 2021
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    Aurora B phosphorylates Bub1 to promote spindle assembly checkpoint signaling
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  88. Nov 2021
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    Interplay between protein acetylation and ubiquitination controls MCL1 protein stability
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    Partial resistance of SARS-CoV-2 Delta variants to vaccine-elicited antibodies and convalescent sera
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    RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy
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    A Note of Caution: Gramicidin Affects Signaling Pathways Independently of Its Effects on Plasma Membrane Conductance
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  93. Oct 2021
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    Liquid culture system for efficient depletion of the endogenous nutrients in Arabidopsis seedlings
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  95. Aug 2021
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    Synthetic biosensor accelerates evolution by rewiring carbon metabolism toward a specific metabolite
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    Investigation of Ldb19/Art1 localization and function at the late Golgi
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    Food Perception Primes Hepatic ER Homeostasis via Melanocortin-Dependent Control of mTOR Activation
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    A Metabolic Checkpoint for the Yeast-to-Hyphae Developmental Switch Regulated by Endogenous Nitric Oxide Signaling
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    Recruitment of Cytosolic J-Proteins by TOM Receptors Promotes Mitochondrial Protein Biogenesis
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  103. Jul 2021
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    Quercetin Enhances the Anti-Tumor Effects of BET Inhibitors by Suppressing hnRNPA1
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    A Metabolic Checkpoint for the Yeast-to-Hyphae Developmental Switch Regulated by Endogenous Nitric Oxide Signaling
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  108. Jun 2021
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    Development and Characterization of Novel Endoxifen-Resistant Breast Cancer Cell Lines Highlight Numerous Differences from Tamoxifen-Resistant Models
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    Multiple pathways of toxicity induced by C9orf72 dipeptide repeat aggregates and G4C2 RNA in a cellular model
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  111. May 2021
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    Heterotrimeric G Protein Subunit Gαq Is a Master Switch for Gβγ-Mediated Calcium Mobilization by Gi-Coupled GPCRs
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    NPC1-mTORC1 Signaling Couples Cholesterol Sensing to Organelle Homeostasis and Is a Targetable Pathway in Niemann-Pick Type C
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  114. Apr 2021
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    Distinct Foxp3 enhancer elements coordinate development, maintenance, and function of regulatory T cells
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    GID E3 ligase supramolecular chelate assembly configures multipronged ubiquitin targeting of an oligomeric metabolic enzyme
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    Intein-mediated cytoplasmic reconstitution of a split toxin enables selective cell ablation in mixed populations and tumor xenografts
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    An ACE2 Microbody Containing a Single Immunoglobulin Fc Domain Is a Potent Inhibitor of SARS-CoV-2
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    Microtubule Attachment and Centromeric Tension Shape the Protein Architecture of the Human Kinetochore
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    Homocysteine promotes hepatic steatosis by activating the adipocyte lipolysis in a HIF1α-ERO1α-dependent oxidative stress manner
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    Recruitment dynamics of ESCRT-III and Vps4 to endosomes and implications for reverse membrane budding
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    A Non-Replicative Role of the 3′ Terminal Sequence of the Dengue Virus Genome in Membranous Replication Organelle Formation
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    The YEATS Domain Histone Crotonylation Readers Control Virulence-Related Biology of a Major Human Pathogen
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    Sleep deprivation regulates availability of PrPC and Aβ peptides which can impair interaction between PrPC and laminin and neuronal plasticity
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    Chromatin Hyperacetylation Impacts Chromosome Folding by Forming a Nuclear Subcompartment
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    Ubiquitin-Conjugating Enzyme 2S Enhances Viral Replication by Inhibiting Type I IFN Production through Recruiting USP15 to Deubiquitinate TBK1
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    Inducible Degradation of the Human SMC5/6 Complex Reveals an Essential Role Only during Interphase
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    Depletion of the MFAP1/SPP381 Splicing Factor Causes R-Loop-Independent Genome Instability
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    Upregulation of the Autophagy Adaptor p62/SQSTM1 Prolongs Health and Lifespan in Middle-Aged Drosophila
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    Impaired Mitochondrial ATP Production Downregulates Wnt Signaling via ER Stress Induction
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    CerS6-Derived Sphingolipids Interact with Mff and Promote Mitochondrial Fragmentation in Obesity
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    p75 Neurotrophin Receptor Activation Regulates the Timing of the Maturation of Cortical Parvalbumin Interneuron Connectivity and Promotes Juvenile-like Plasticity in Adult Visual Cortex
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    Fork Cleavage-Religation Cycle and Active Transcription Mediate Replication Restart after Fork Stalling at Co-transcriptional R-Loops
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    ATG5 cancer mutations and alternative mRNA splicing reveal a conjugation switch that regulates ATG12–ATG5-ATG16L1 complex assembly and autophagy
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    Interconversion between Anticipatory and Active GID E3 Ubiquitin Ligase Conformations via Metabolically Driven Substrate Receptor Assembly
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    Signaling pathways in cytoskeletal responses to plasma membrane depolarization in corneal endothelial cells
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    TRAIP drives replisome disassembly and mitotic DNA repair synthesis at sites of incomplete DNA replication
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    Insulin/IGF-1 Drives PERIOD Synthesis to Entrain Circadian Rhythms with Feeding Time
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  161. Nov 2018
  162. elifesciences.org elifesciences.org
    Epigenetic drift of H3K27me3 in aging links glycolysis to healthy longevity in Drosophila
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    Arabidopsis ARGONAUTE 1 Binds Chromatin to Promote Gene Transcription in Response to Hormones and Stresses
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    Actin Cross-Linking Toxin Is a Universal Inhibitor of Tandem-Organized and Oligomeric G-Actin Binding Proteins
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    Repurposing HAMI3379 to Block GPR17 and Promote Rodent and Human Oligodendrocyte Differentiation
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    Intrinsic Ribosome Destabilization Underlies Translation and Provides an Organism with a Strategy of Environmental Sensing
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    NOTCH2 Hajdu-Cheney Mutations Escape SCFFBW7-Dependent Proteolysis to Promote Osteoporosis
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    Engineered Multivalent Sensors to Detect Coexisting Histone Modifications in Living Stem Cells
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  172. Nov 2017
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    RECQ5 Helicase Cooperates with MUS81 Endonuclease in Processing Stalled Replication Forks at Common Fragile Sites during Mitosis
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  174. f1000research.com f1000research.com
    Reactivity of vertebrate-directed phospho-eEF2 antibody against the <i>Caenorhabditis elegans </i>orthologue phospho-EEF-2
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      Curator: @bandrow

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