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Therapeutic Gfral silencing via antisense oligonucleotides ameliorates cancer-associated cachexia and extends survival in tumor-bearing mice

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1. scibot 28 Jul 2026
  
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  RRID:AB_2607220
  
  DOI: 10.1016/j.xcrm.2026.102939
  
  Resource: (Thermo Fisher Scientific Cat# PA5-47769, RRID:AB_2607220)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S2666379126003563
Feb 2026
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Deletion of Mfn2 in endothelial cells triggers a mitohormetic response that improves systemic metabolism and healthspan in mice

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1. scibot 19 Feb 2026
  
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  RRID:AB_2607220
  
  DOI: 10.1016/j.cmet.2026.01.012
  
  Resource: (Thermo Fisher Scientific Cat# PA5-47769, RRID:AB_2607220)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S1550413126000124
Oct 2025
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The upregulation of GDF15 is controlled epigenetically by oncogenic TCF19 signaling in human hepatocellular carcinoma

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1. scibot 09 Oct 2025
  
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  RRID:AB_2607220
  
  DOI: 10.1016/j.isci.2025.113503
  
  Resource: (Thermo Fisher Scientific Cat# PA5-47769, RRID:AB_2607220)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S258900422501764X
May 2025
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Semaglutide effects on energy balance are mediated by Adcyap1+ neurons in the dorsal vagal complex

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1. scibot 29 May 2025
  
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  RRID:AB_2607220
  
  DOI: 10.1016/j.cmet.2025.04.018
  
  Resource: (Thermo Fisher Scientific Cat# PA5-47769, RRID:AB_2607220)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S1550413125002566
Mar 2024
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Activation of GFRAL+ neurons induces hypothermia and glucoregulatory responses associated with nausea and torpor

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1. scibot 21 Mar 2024
  
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  RRID:AB_2607220
  
  DOI: 10.1016/j.celrep.2024.113960
  
  Resource: (Thermo Fisher Scientific Cat# PA5-47769, RRID:AB_2607220)
  
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sciencedirect.com/science/article/pii/S2211124724002882
Sep 2020
elifesciences.org elifesciences.org

The cytokine GDF15 signals through a population of brainstem cholecystokinin neurons to mediate anorectic signalling

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1. scibot 26 Sep 2020
  
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  RRID:AB_2607220
  
  DOI: 10.7554/eLife.55164
  
  Resource: (Thermo Fisher Scientific Cat# PA5-47769, RRID:AB_2607220)
  
  Curator: @evieth
  
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  RRIDCUR:Validated RRID:AB_2607220
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elifesciences.org/articles/55164
Jan 2020
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GDF15 Induces Anorexia through Nausea and Emesis

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1. scibot 13 Jan 2020
  
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  RRID:AB_2607220
  
  DOI: 10.1016/j.cmet.2019.12.004
  
  Resource: (Thermo Fisher Scientific Cat# PA5-47769, RRID:AB_2607220)
  
  Curator: @ethanbadger
  
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sciencedirect.com/science/article/pii/S1550413119306692