64 Matching Annotations
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    MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons
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    sciencedirect.com/science/article/pii/S0896627324002459
  3. Apr 2024
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    SAFB restricts contact domain boundaries associated with L1 chimeric transcription
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    sciencedirect.com/science/article/pii/S1097276524002314
  5. Mar 2024
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    Nuclear microRNA-mediated transcriptional control determines adult microglial homeostasis and brain function
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  7. Feb 2024
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    EZH2 Inhibition Promotes Tumor Immunogenicity in Lung Squamous Cell Carcinomas
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    FOXA1 forms biomolecular condensates that unpack condensed chromatin to function as a pioneer factor
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  10. Jan 2024
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    PCGF6 controls murine Tuft cell differentiation via H3K9me2 modification independently of Polycomb repression
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    sciencedirect.com/science/article/pii/S1534580723006962
  12. Nov 2023
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    Scalable single-cell profiling of chromatin modifications with sciCUT&Tag
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    LINE-1 retrotransposons drive human neuronal transcriptome complexity and functional diversification
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    LINE-1 retrotransposons drive human neuronal transcriptome complexity and functional diversification
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    ncbi.nlm.nih.gov/pmc/articles/PMC10619931/
  16. Oct 2023
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    Gcn5- and Bre1-mediated Set2 degradation promotes chronological aging of Saccharomyces cerevisiae
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    sciencedirect.com/science/article/pii/S2211124723011981
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    Hypoxia activates SREBP2 through Golgi disassembly in bone marrow-derived monocytes for enhanced tumor growth
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    embopress.org/doi/10.15252/embj.2023114032
  19. Sep 2023
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Histone bivalency regulates the timing of cerebellar granule cell development
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    ncbi.nlm.nih.gov/pmc/articles/PMC10499015/
  21. Jun 2023
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    Pyruvate metabolism controls chromatin remodeling during CD4+ T cell activation
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    sciencedirect.com/science/article/pii/S2211124723005946
  23. May 2023
  24. www.biorxiv.org www.biorxiv.org
    L1 retrotransposons drive human neuronal transcriptome complexity and functional diversification
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  25. Apr 2023
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    Evolutionarily distinct and sperm-specific supersized chromatin loops are marked by Helitron transposons in Xenopus tropicalis
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    Transient suppression of SUMOylation in embryonic stem cells generates embryo-like structures
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    Targeting the mevalonate pathway suppresses ARID1A-inactivated cancers by promoting pyroptosis
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    sciencedirect.com/science/article/pii/S1535610823000508
  29. Mar 2023
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    KDM6A Loss Triggers an Epigenetic Switch That Disrupts Urothelial Differentiation and Drives Cell Proliferation in Bladder Cancer
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    Histone bivalency regulates the timing of cerebellar granule cell development
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  32. Feb 2023
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    Bat pluripotent stem cells reveal unusual entanglement between host and viruses
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    sciencedirect.com/science/article/pii/S0092867423000417
  34. Jan 2023
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    Multi-omics profiling visualizes dynamics of cardiac development and functions
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    sciencedirect.com/science/article/pii/S2211124722017909
  36. Dec 2022
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    SETD1A regulates transcriptional pause release of heme biosynthesis genes in leukemia
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  38. Nov 2022
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    Tip60-mediated H2A.Z acetylation promotes neuronal fate specification and bivalent gene activation
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    Metabolic regulation by p53 prevents R-loop-associated genomic instability
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  41. Mar 2022
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    The BTB transcription factors ZBTB11 and ZFP131 maintain pluripotency by repressing pro-differentiation genes
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    Transcription factor Hhex negatively regulates osteoclast differentiation by controlling cyclin-dependent kinase inhibitors
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  44. Feb 2022
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    Activation-induced chromatin reorganization in neurons depends on HDAC1 activity
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  46. Dec 2021
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    5-Hydroxymethylcytosine-mediated active demethylation is required for mammalian neuronal differentiation and function
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  48. Nov 2021
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    Cell division- and DNA replication-free reprogramming of somatic nuclei for embryonic transcription
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    sciencedirect.com/science/article/pii/S2589004221012591
  50. Oct 2021
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    Increased ACTL6A occupancy within mSWI/SNF chromatin remodelers drives human squamous cell carcinoma
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    sciencedirect.com/science/article/pii/S1097276521008340
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    A cis-acting structural variation at the ZNF558 locus controls a gene regulatory network in human brain development
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    sciencedirect.com/science/article/pii/S1934590921003842
  53. Sep 2021
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HBO1-MLL interaction promotes AF4/ENL/P-TEFb-mediated leukemogenesis
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    ncbi.nlm.nih.gov/pmc/articles/PMC8387021/
  55. Aug 2021
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    KDM5A suppresses PML-RARα target gene expression and APL differentiation through repressing H3K4me2
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    sciencedirect.com/science/article/pii/S2473952921004171
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    Enhancer decommissioning imposes an epigenetic barrier to sensory hair cell regeneration
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    sciencedirect.com/science/article/pii/S1534580721005591
  58. Jul 2021
  59. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    sciencedirect.com/science/article/pii/S153561081830535X
  60. Jun 2021
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SIRT1 regulates sphingolipid metabolism and neural differentiation of mouse embryonic stem cells through c-Myc-SMPDL3B
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    ncbi.nlm.nih.gov/pmc/articles/PMC8216717/
  62. May 2021
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    Chromatin accessibility governs the differential response of cancer and T cells to arginine starvation
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    m6A Modification Prevents Formation of Endogenous Double-Stranded RNAs and Deleterious Innate Immune Responses during Hematopoietic Development
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    sciencedirect.com/science/article/pii/S1074761320301849
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    Stromal SOX2 Upregulation Promotes Tumorigenesis through the Generation of a SFRP1/2-Expressing Cancer-Associated Fibroblast Population
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    sciencedirect.com/science/article/pii/S1534580720308340
  66. Apr 2021
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    Integrated Metabolic and Epigenomic Reprograming by H3K27M Mutations in Diffuse Intrinsic Pontine Gliomas
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      DOI: 10.1016/j.ccell.2020.07.008

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  68. Mar 2021
  69. www.sciencedirect.com www.sciencedirect.com
    H3.3-K27M drives neural stem cell-specific gliomagenesis in a human iPSC-derived model
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      DOI: 10.1016/j.ccell.2021.01.005

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  70. Feb 2021
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    The histone demethylase KDM5 is required for synaptic structure and function at the Drosophila neuromuscular junction
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      DOI: 10.1016/j.celrep.2021.108753

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  72. Sep 2020
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    Activation of CpG-Rich Promoters Mediated by MLL Drives MOZ-Rearranged Leukemia
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      DOI: 10.1016/j.celrep.2020.108200

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  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Large domains of heterochromatin direct the formation of short mitotic chromosome loops
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      DOI: 10.7554/eLife.57212

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  75. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Loss of Extreme Long-Range Enhancers in Human Neural Crest Drives a Craniofacial Disorder
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      DOI: 10.1016/j.stem.2020.09.001

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  76. elifesciences.org elifesciences.org
    Systematic perturbation of retroviral LTRs reveals widespread long-range effects on human gene regulation
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      DOI: 10.7554/eLife.35989

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    ZBTB1 Regulates Asparagine Synthesis and Leukemia Cell Response to L-Asparaginase
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      DOI: 10.1016/j.cmet.2020.03.008

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  78. Jan 2020
  79. academic.oup.com academic.oup.com
    HUMAN TROPHOBLAST DIFFERENTIATION IS ASSOCIATED WITH PROFOUND GENE REGULATORY AND EPIGENETIC CHANGES
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      DOI: 10.1210/en.2019-00144

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    DNA Hypermethylation Encroachment at CpG Island Borders in Cancer Is Predisposed by H3K4 Monomethylation Patterns
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      DOI: 10.1016/j.ccell.2019.01.004

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    Inhibiting Inflammation with Myeloid Cell-Specific Nanobiologics Promotes Organ Transplant Acceptance
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      DOI: 10.1016/j.immuni.2018.09.008

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      DOI: 10.1016/j.stem.2018.12.012

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  84. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Cooperation of PU.1 With IRF8 and NFATc1 Defines Chromatin Landscapes During RANKL‐Induced Osteoclastogenesis
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      DOI: 10.1002/jbmr.3689

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  85. Nov 2018
  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  87. www.sciencedirect.com www.sciencedirect.com
    Examining the Roles of H3K4 Methylation States with Systematically Characterized Antibodies
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    Increased Lactate Secretion by Cancer Cells Sustains Non-cell-autonomous Adaptive Resistance to MET and EGFR Targeted Therapies
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    Identification of Therapeutic Targets in Rhabdomyosarcoma through Integrated Genomic, Epigenomic, and Proteomic Analyses
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    Promoter of lncRNA Gene PVT1 Is a Tumor-Suppressor DNA Boundary Element
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  91. Nov 2017
  92. www.sciencedirect.com www.sciencedirect.com
    Aging Triggers Cytoplasmic Depletion and Nuclear Translocation of the E3 Ligase Mahogunin: A Function for Ubiquitin in Neuronal Survival
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      Curator: @chewbeccax

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    sciencedirect.com/science/article/pii/S1097276517302356
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    Mll3 and Mll4 Facilitate Enhancer RNA Synthesis and Transcription from Promoters Independently of H3K4 Monomethylation
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    sciencedirect.com/science/article/pii/S1097276517302745
  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ciliary transcription factors and miRNAs precisely regulate Cp110 levels required for ciliary adhesions and ciliogenesis
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      H3K4me3

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    ncbi.nlm.nih.gov/pmc/articles/PMC5045295/
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    A Multi-step Transcriptional and Chromatin State Cascade Underlies Motor Neuron Programming from Embryonic Stem Cells
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    sciencedirect.com/science/article/pii/S1934590916304027
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    Inheritable Silencing of Endogenous Genes by Hit-and-Run Targeted Epigenetic Editing
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    sciencedirect.com/science/article/pii/S0092867416312363