284 Matching Annotations
  1. Apr 2021
  2. link.springer.com link.springer.com
    Multi-omic profiling of pituitary thyrotropic cells and progenitors
    1
    1. scibot 20 Apr 2021
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      DOI: 10.1186/s12915-021-01009-0

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    link.springer.com/article/10.1186/s12915-021-01009-0
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    SETD2 Restricts Prostate Cancer Metastasis by Integrating EZH2 and AMPK Signaling Pathways
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    1. scibot 17 Apr 2021
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      DOI: 10.1016/j.ccell.2020.05.022

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    sciencedirect.com/science/article/pii/S1535610820302725
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    SETD5-Coordinated Chromatin Reprogramming Regulates Adaptive Resistance to Targeted Pancreatic Cancer Therapy
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    1. scibot 17 Apr 2021
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      DOI: 10.1016/j.ccell.2020.04.014

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    sciencedirect.com/science/article/pii/S1535610820302130
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    UTX promotes CD8+ T cell-mediated antiviral defenses but reduces T cell durability
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    1. scibot 15 Apr 2021
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      DOI: 10.1016/j.celrep.2021.108966

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    sciencedirect.com/science/article/pii/S2211124721002801
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    Dual targeting of the epigenome via FACT complex and histone deacetylase is a potent treatment strategy for DIPG
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    1. scibot 14 Apr 2021
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      DOI: 10.1016/j.celrep.2021.108994

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    sciencedirect.com/science/article/pii/S2211124721003089
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    The SMC5/6 complex compacts and silences unintegrated HIV-1 DNA and is antagonized by Vpr
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    1. scibot 03 Apr 2021
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      DOI: 10.1016/j.chom.2021.03.001

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    sciencedirect.com/science/article/pii/S1931312821001013
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    mTORC1 stimulates cell growth through SAM synthesis and m6A mRNA-dependent control of protein synthesis
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    1. scibot 02 Apr 2021
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      DOI: 10.1016/j.molcel.2021.03.009

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    sciencedirect.com/science/article/pii/S1097276521001775
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    Gut microbial metabolites facilitate anticancer therapy efficacy by modulating cytotoxic CD8+ T cell immunity
    1
    1. scibot 02 Apr 2021
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      DOI: 10.1016/j.cmet.2021.03.002

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    sciencedirect.com/science/article/pii/S1550413121001091
  10. Mar 2021
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Embryonic Stem-Cell-Derived Extracellular Vesicles Maintain ESC Stemness by Activating FAK
    1
    1. scibot 31 Mar 2021
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      DOI: 10.1016/j.devcel.2020.11.017

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    ncbi.nlm.nih.gov/pmc/articles/PMC8005871/
  12. Feb 2021
  13. www.sciencedirect.com www.sciencedirect.com
    Histone H3.3G34-Mutant Interneuron Progenitors Co-opt PDGFRA for Gliomagenesis
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    1. scibot 28 Feb 2021
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      DOI: 10.1016/j.cell.2020.11.012

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    sciencedirect.com/science/article/pii/S0092867420315294
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TASOR is a pseudo-PARP that directs HUSH complex assembly and epigenetic transposon control
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    1. scibot 27 Feb 2021
      RRID:AB_2616029

      DOI: 10.1038/s41467-020-18761-6

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    ncbi.nlm.nih.gov/pmc/articles/PMC7532188/
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    Regional identity of human neural stem cells determines oncogenic responses to histone H3.3 mutants
    1
    1. scibot 25 Feb 2021
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      DOI: 10.1016/j.stem.2021.01.016

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    sciencedirect.com/science/article/pii/S1934590921000163
  16. www.cell.com www.cell.com
    Definition of a small core transcriptional circuit regulated by AML1-ETO
    1
    1. scibot 25 Feb 2021
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      DOI: 10.1016/j.molcel.2020.12.005

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    cell.com/molecular-cell/abstract/S1097-2765(20)30897-2
  17. www.sciencedirect.com www.sciencedirect.com
    Chromatin dysregulation associated with NSD1 mutation in head and neck squamous cell carcinoma
    1
    1. scibot 25 Feb 2021
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      DOI: 10.1016/j.celrep.2021.108769

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    sciencedirect.com/science/article/pii/S2211124721000826
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    Competition between PRC2.1 and 2.2 subcomplexes regulates PRC2 chromatin occupancy in human stem cells
    1
    1. scibot 24 Feb 2021
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      DOI: 10.1016/j.molcel.2020.11.044

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    sciencedirect.com/science/article/pii/S1097276520308868
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    An acetyl-histone vulnerability in PI3K/AKT inhibition-resistant cancers is targetable by both BET and HDAC inhibitors
    1
    1. scibot 24 Feb 2021
      RRID:AB_2616029

      DOI: 10.1016/j.celrep.2021.108744

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    sciencedirect.com/science/article/pii/S2211124721000577
  20. Jan 2021
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Stage-specific roles of Ezh2 and Retinoic acid signaling ensure calvarial bone lineage commitment.
    1
    1. scibot 05 Jan 2021
      AB_26160629

      DOI: 10.1016/j.ydbio.2018.09.014

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    ncbi.nlm.nih.gov/pmc/articles/PMC6217976/
  22. Dec 2020
  23. elifesciences.org elifesciences.org
    Efficient chromatin accessibility mapping in situ by nucleosome-tethered tagmentation
    1
    1. scibot 12 Dec 2020
      RRID:AB_2616029

      DOI: 10.7554/eLife.63274

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    elifesciences.org/articles/63274
  24. Nov 2020
  25. www.sciencedirect.com www.sciencedirect.com
    H3K27M in Gliomas Causes a One-Step Decrease in H3K27 Methylation and Reduced Spreading within the Constraints of H3K36 Methylation
    1
    1. scibot 25 Nov 2020
      RRID:AB_2616029

      DOI: 10.1016/j.celrep.2020.108390

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    sciencedirect.com/science/article/pii/S2211124720313796
  26. www.cell.com www.cell.com
    Formation of the CenH3-Deficient Holocentromere in Lepidoptera Avoids Active Chromatin
    1
    1. scibot 20 Nov 2020
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      DOI: 10.1016/j.cub.2020.09.078

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    cell.com/current-biology/abstract/S0960-9822(20)31448-2
  27. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    ARID1A Mutations Promote P300-Dependent Endometrial Invasion through Super-Enhancer Hyperacetylation
    1
    1. scibot 14 Nov 2020
      RRID:AB_2616029

      DOI: 10.1016/j.celrep.2020.108366

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    pubmed.ncbi.nlm.nih.gov/33176148/
  28. www.sciencedirect.com www.sciencedirect.com
    Metabolic Reprogramming Induces Germinal Center B Cell Differentiation through Bcl6 Locus Remodeling
    1
    1. scibot 07 Nov 2020
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      DOI: 10.1016/j.celrep.2020.108333

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    sciencedirect.com/science/article/pii/S221112472031322X
  29. Oct 2020
  30. www.cell.com www.cell.com
    Senescence Induced by BMI1 Inhibition Is a Therapeutic Vulnerability in H3K27M-Mutant DIPG
    1
    1. scibot 24 Oct 2020
      RRID:AB_2616029

      DOI: 10.1016/j.celrep.2020.108286

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    cell.com/cell-reports/abstract/S2211-1247(20)31275-4
  31. www.sciencedirect.com www.sciencedirect.com
    Bone Morphogenic Proteins Are Immunoregulatory Cytokines Controlling FOXP3+ Treg Cells
    1
    1. scibot 08 Oct 2020
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      DOI: 10.1016/j.celrep.2020.108219

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    sciencedirect.com/science/article/pii/S2211124720312080
  32. Sep 2020
  33. www.sciencedirect.com www.sciencedirect.com
    Mutant EZH2 Induces a Pre-malignant Lymphoma Niche by Reprogramming the Immune Response
    1
    1. scibot 25 Sep 2020
      RRID:AB_2616029

      DOI: 10.1016/j.ccell.2020.04.004

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    sciencedirect.com/science/article/pii/S1535610820302038
  34. www.sciencedirect.com www.sciencedirect.com
    Global Regulatory DNA Potentiation by SMARCA4 Propagates to Selective Gene Expression Programs via Domain-Level Remodeling
    1
    1. scibot 23 Sep 2020
      RRID:AB_2616029

      DOI: 10.1016/j.celrep.2020.107676

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    sciencedirect.com/science/article/pii/S221112472030629X
  35. www.sciencedirect.com www.sciencedirect.com
    Domain Model Explains Propagation Dynamics and Stability of Histone H3K27 and H3K36 Methylation Landscapes
    1
    1. scibot 17 Sep 2020
      RRID:AB_2616029

      DOI: 10.1016/j.celrep.2019.12.060

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    sciencedirect.com/science/article/pii/S2211124719317176
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    A Dimeric Structural Scaffold for PRC2-PCL Targeting to CpG Island Chromatin
    1
    1. scibot 16 Sep 2020
      RRID:AB_2616029

      DOI: 10.1016/j.molcel.2019.12.019

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    sciencedirect.com/science/article/pii/S1097276519309499
  37. www.sciencedirect.com www.sciencedirect.com
    Dissecting Murine Muscle Stem Cell Aging through Regeneration Using Integrative Genomic Analysis
    1
    1. scibot 10 Sep 2020
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      DOI: 10.1016/j.celrep.2020.107964

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    sciencedirect.com/science/article/pii/S2211124720309451
  38. www.sciencedirect.com www.sciencedirect.com
    Heterochromatin-Driven Nuclear Softening Protects the Genome against Mechanical Stress-Induced Damage
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    1. scibot 10 Sep 2020
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      DOI: 10.1016/j.cell.2020.03.052

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    sciencedirect.com/science/article/pii/S0092867420303457
  39. www.sciencedirect.com www.sciencedirect.com
    Epigenetic Silencing of CDR1as Drives IGF2BP3-Mediated Melanoma Invasion and Metastasis
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    1. scibot 10 Sep 2020
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      DOI: 10.1016/j.ccell.2019.12.007

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    sciencedirect.com/science/article/pii/S153561081930577X
  40. www.sciencedirect.com www.sciencedirect.com
    EZH2 Inhibition Sensitizes CARM1-High, Homologous Recombination Proficient Ovarian Cancers to PARP Inhibition
    1
    1. scibot 09 Sep 2020
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      DOI: 10.1016/j.ccell.2019.12.015

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    sciencedirect.com/science/article/pii/S1535610819305859
  41. www.sciencedirect.com www.sciencedirect.com
    Cdk1 Controls Global Epigenetic Landscape in Embryonic Stem Cells
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    1. scibot 09 Sep 2020
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      DOI: 10.1016/j.molcel.2020.03.010

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    sciencedirect.com/science/article/pii/S1097276520301581
  42. www.sciencedirect.com www.sciencedirect.com
    NeuroD1 Dictates Tumor Cell Differentiation in Medulloblastoma
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      DOI: 10.1016/j.celrep.2020.107782

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    sciencedirect.com/science/article/pii/S2211124720307622
  43. www.sciencedirect.com www.sciencedirect.com
    A Deregulated HOX Gene Axis Confers an Epigenetic Vulnerability in KRAS-Mutant Lung Cancers
    1
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      DOI: 10.1016/j.ccell.2020.03.004

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    sciencedirect.com/science/article/pii/S1535610820301057
  44. www.cell.com www.cell.com
    Aging Suppresses Skin-Derived Circulating SDF1 to Promote Full-Thickness Tissue Regeneration
    1
    1. scibot 04 Sep 2020
      RRID: AB_2616029

      DOI: 10.1016/j.celrep.2018.08.054

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    cell.com/cell-reports/fulltext/S2211-1247(18)31340-8
  45. www.sciencedirect.com www.sciencedirect.com
    Super Elongation Complex as a Targetable Dependency in Diffuse Midline Glioma
    1
    1. scibot 04 Sep 2020
      Tri-Methyl-Histone H3 (Lys27) rabbit mAb

      DOI: 10.1016/j.celrep.2020.03.049

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    sciencedirect.com/science/article/pii/S2211124720303636
  46. www.sciencedirect.com www.sciencedirect.com
    Methionine Metabolism Shapes T Helper Cell Responses through Regulation of Epigenetic Reprogramming
    1
    1. scibot 04 Sep 2020
      Rabbit monoclonal anti-mouse Tri-methyl-Histone H3 (Lys27) (1:2000 dilution)

      DOI: 10.1016/j.cmet.2020.01.006

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    sciencedirect.com/science/article/pii/S1550413120300061
  47. rupress.org rupress.org
    Glioma stem-like cells evade interferon suppression through MBD3/NuRD complex–mediated STAT1 downregulation
    1
    1. scibot 04 Sep 2020
      RRID:AB_2616029

      DOI: 10.1084/jem.20191340

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  48. mcr.aacrjournals.org mcr.aacrjournals.org
    Dual Regulation of Histone Methylation by mTOR Complexes Controls Glioblastoma Tumor Cell Growth via EZH2 and SAM
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    Genome-wide R-loop Landscapes during Cell Differentiation and Reprogramming
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  51. Jan 2020
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    One-Carbon Metabolism Supports S-Adenosylmethionine and Histone Methylation to Drive Inflammatory Macrophages
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    A Functional Link between Nuclear RNA Decay and Transcriptional Control Mediated by the Polycomb Repressive Complex 2
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    Antagonistic interaction between Ezh2 and Arid1a coordinates root patterning and development via Cdkn2a in mouse molars
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    Rapid Generation of Somatic Mouse Mosaics with Locus-Specific, Stably Integrated Transgenic Elements
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    EED-Targeted PROTACs Degrade EED, EZH2, and SUZ12 in the PRC2 Complex
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    Quantitative Multiplexed ChIP Reveals Global Alterations that Shape Promoter Bivalency in Ground State Embryonic Stem Cells
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    DEAD-Box Helicase 18 Counteracts PRC2 to Safeguard Ribosomal DNA in Pluripotency Regulation
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    An Evolutionarily Conserved Function of Polycomb Silences the MHC Class I Antigen Presentation Pathway and Enables Immune Evasion in Cancer
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    Regulation of EZH2 by SMYD2-Mediated Lysine Methylation Is Implicated in Tumorigenesis
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    lncRNA-Induced Spread of Polycomb Controlled by Genome Architecture, RNA Abundance, and CpG Island DNA
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    Quantification of Proteins and Histone Marks in Drosophila Embryos Reveals Stoichiometric Relationships Impacting Chromatin Regulation
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    Active and Repressed Chromatin Domains Exhibit Distinct Nucleosome Segregation during DNA Replication
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    PPEF2 Opposes PINK1-Mediated Mitochondrial Quality Control by Dephosphorylating Ubiquitin
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    Polycomb Group Proteins Regulate Chromatin Architecture in Mouse Oocytes and Early Embryos
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    HUMAN TROPHOBLAST DIFFERENTIATION IS ASSOCIATED WITH PROFOUND GENE REGULATORY AND EPIGENETIC CHANGES
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    The COMPASS Family Protein ASH2L Mediates Corticogenesis via Transcriptional Regulation of Wnt Signaling
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    Small Molecule Inhibitors of KDM5 Histone Demethylases Increase the Radiosensitivity of Breast Cancer Cells Overexpressing JARID1B
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    Histone H2AK119 Mono-Ubiquitination Is Essential for Polycomb-Mediated Transcriptional Repression
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    The Short Chain Fatty Acid Butyrate Imprints an Antimicrobial Program in Macrophages
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    Targeting Epigenetic Crosstalk as a Therapeutic Strategy for EZH2-Aberrant Solid Tumors
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    Mutant NPM1 Maintains the Leukemic State through HOX Expression
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    Increased Lactate Secretion by Cancer Cells Sustains Non-cell-autonomous Adaptive Resistance to MET and EGFR Targeted Therapies
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    Dppa2/4 Facilitate Epigenetic Remodeling during Reprogramming to Pluripotency
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    EZH2-Mediated Primary Cilium Deconstruction Drives Metastatic Melanoma Formation
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    MicroRNAs Overcome Cell Fate Barrier by Reducing EZH2-Controlled REST Stability during Neuronal Conversion of Human Adult Fibroblasts
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    Capturing the Onset of PRC2-Mediated Repressive Domain Formation
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    Targeting the Senescence-Overriding Cooperative Activity of Structurally Unrelated H3K9 Demethylases in Melanoma
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    The SS18-SSX Oncoprotein Hijacks KDM2B-PRC1.1 to Drive Synovial Sarcoma
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    A Family of Vertebrate-Specific Polycombs Encoded by the LCOR/LCORL Genes Balance PRC2 Subtype Activities
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    sciencedirect.com/science/article/pii/S1097276518301862
  90. www.sciencedirect.com www.sciencedirect.com
    The H3K36me2 Methyltransferase Nsd1 Demarcates PRC2-Mediated H3K27me2 and H3K27me3 Domains in Embryonic Stem Cells
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    1. scibot 05 Nov 2018
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    sciencedirect.com/science/article/pii/S1097276518301722
  91. www.sciencedirect.com www.sciencedirect.com
    A Non-canonical BCOR-PRC1.1 Complex Represses Differentiation Programs in Human ESCs
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    1. scibot 05 Nov 2018
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    sciencedirect.com/science/article/pii/S1934590917305027
  92. www.sciencedirect.com www.sciencedirect.com
    The Elongation Factor Spt6 Maintains ESC Pluripotency by Controlling Super-Enhancers and Counteracting Polycomb Proteins
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    1. scibot 05 Nov 2018
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    sciencedirect.com/science/article/pii/S1097276517306676
  93. www.sciencedirect.com www.sciencedirect.com
    H3.3K27M Cooperates with Trp53 Loss and PDGFRA Gain in Mouse Embryonic Neural Progenitor Cells to Induce Invasive High-Grade Gliomas
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    sciencedirect.com/science/article/pii/S153561081730418X
  94. Nov 2017
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    Ubiquitination-Deficient Mutations in Human Piwi Cause Male Infertility by Impairing Histone-to-Protamine Exchange during Spermiogenesis
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    1. scibot 08 Nov 2017
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      Curator: @Zeljana_Babic

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    sciencedirect.com/science/article/pii/S0092867417304889
  96. www.sciencedirect.com www.sciencedirect.com
    Gene Resistance to Transcriptional Reprogramming following Nuclear Transfer Is Directly Mediated by Multiple Chromatin-Repressive Pathways
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    1. scibot 08 Nov 2017
      AB_2616029

      Curator: @Zeljana_Babic

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