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May 2026
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miR-93-mediated PTEN suppression and CNS-specific T cell exhaustion shape the leukemia niche in infant KMT2A::AFF1+ B-ALL

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sciencedirect.com/science/article/pii/S2211124726004316
Nov 2025
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Transcription factor Zfx regulates tumor’s evasion to T cell killing in immunotherapy

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  DOI: 10.1016/j.isci.2025.113842
  
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sciencedirect.com/science/article/pii/S2589004225021030
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Developing a therapeutic elastase that stimulates anti-tumor immunity by selectively killing cancer cells

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1. scibot 13 Nov 2025
  
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sciencedirect.com/science/article/pii/S2666379125005191
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Microbiota-derived butyrate promotes a FOXO1-induced stemness program and preserves CD8+ T cell immunity against melanoma

1
1. scibot 05 Nov 2025
  
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sciencedirect.com/science/article/pii/S1074761325004340
Oct 2025
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Eomesodermin+ CD4+ T cells are critical for curative immunotherapy outcomes

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1. scibot 04 Oct 2025
  
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sciencedirect.com/science/article/pii/S1074761325004157
Jul 2025
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The costimulatory molecule ICOS limits memory-like properties and function of exhausted PD-1+CD8+ T cells

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1. scibot 08 Jul 2025
  
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  DOI: 10.1016/j.immuni.2025.06.001
  
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sciencedirect.com/science/article/pii/S1074761325002481
May 2025
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Regulatory T cell depletion promotes myeloid cell activation and glioblastoma response to anti-PD1 and tumor-targeting antibodies

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  DOI: 10.1016/j.immuni.2025.03.021
  
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sciencedirect.com/science/article/pii/S1074761325001621
Apr 2025
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Bro1 proteins determine tumor immune evasion and metastasis by controlling secretion or degradation of multivesicular bodies

1
1. scibot 05 Apr 2025
  
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  DOI: 10.1016/j.devcel.2025.03.008
  
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sciencedirect.com/science/article/pii/S1534580725001558
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Immune targeting and host-protective effects of the latent stage of Toxoplasma gondii

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1. scibot 02 Apr 2025
  
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  DOI: 10.1038/s41564-025-01967-z
  
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nature.com/articles/s41564-025-01967-z
Aug 2024
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Aerobic glycolysis but not GLS1-dependent glutamine metabolism is critical for anti-tumor immunity and response to checkpoint inhibition

1
1. scibot 22 Aug 2024
  
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  DOI: 10.1016/j.celrep.2024.114632
  
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sciencedirect.com/science/article/pii/S2211124724009823
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LAG-3 sustains TOX expression and regulates the CD94/NKG2-Qa-1b axis to govern exhausted CD8 T cell NK receptor expression and cytotoxicity

1
1. scibot 20 Aug 2024
  
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  DOI: 10.1016/j.cell.2024.07.018
  
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sciencedirect.com/science/article/pii/S0092867424007785
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LAG-3 and PD-1 synergize on CD8+ T cells to drive T cell exhaustion and hinder autocrine IFN-γ-dependent anti-tumor immunity

1
1. scibot 20 Aug 2024
  
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  DOI: 10.1016/j.cell.2024.07.016
  
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sciencedirect.com/science/article/pii/S0092867424007761
Jul 2024
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Preclinical study and phase II trial of adapting low-dose radiotherapy to immunotherapy in small cell lung cancer

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1. scibot 19 Jul 2024
  
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  DOI: 10.1016/j.medj.2024.06.002
  
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sciencedirect.com/science/article/pii/S2666634024002484
Jun 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Sonogenetics-controlled synthetic designer cells for cancer therapy in tumor mouse models

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1. scibot 08 Jun 2024
  
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  DOI: 10.1016/j.xcrm.2024.101513
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11148564/
May 2024
www.biorxiv.org www.biorxiv.org

The latent stage of Toxoplasma gondii is targeted by the immune response and host protective

1
1. scibot 24 May 2024
  
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  DOI: 10.1101/2024.03.05.583527
  
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biorxiv.org/content/10.1101/2024.03.05.583527v1
Apr 2024
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The diversity of inhibitory receptor co-expression patterns of exhausted CD8+ T cells in oropharyngeal carcinoma

1
1. scibot 28 Apr 2024
  
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  DOI: 10.1016/j.isci.2024.109668
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11035373/
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Cancer SLC6A6-mediated taurine uptake transactivates immune checkpoint genes and induces exhaustion in CD8+ T cells

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1. scibot 02 Apr 2024
  
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  RRID:AB_2616907
  
  DOI: 10.1016/j.cell.2024.03.011
  
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sciencedirect.com/science/article/pii/S0092867424003039
Feb 2024
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LAG-3- and CXCR5-expressing CD4 T cells display progenitor-like properties during chronic visceral leishmaniasis

2
1. scibot 29 Feb 2024
  
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  DOI: 10.1016/j.celrep.2024.113879
  
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2. scibot 29 Feb 2024
  
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  DOI: 10.1016/j.celrep.2024.113879
  
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sciencedirect.com/science/article/pii/S2211124724002079
Dec 2023
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Stat5 opposes the transcription factor Tox and rewires exhausted CD8+ T cells toward durable effector-like states during chronic antigen exposure

1
1. scibot 17 Dec 2023
  
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  DOI: 10.1016/j.immuni.2023.11.005
  
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sciencedirect.com/science/article/pii/S1074761323004879
Nov 2023
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The antitumor activities of anti-CD47 antibodies require Fc-FcγR interactions

1
1. scibot 28 Nov 2023
  
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  DOI: 10.1016/j.ccell.2023.10.007
  
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sciencedirect.com/science/article/pii/S153561082300363X
Sep 2023
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Interferon-g-dependent interactions between tissue-intrinsic γδ T cells and tissue-infiltrating CD8 T cells limit acute contact dermatitis

1
1. scibot 29 Sep 2023
  
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  DOI: 10.1016/j.jaci.2023.07.015
  
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sciencedirect.com/science/article/pii/S0091674923009818
Jun 2023
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The SWI/SNF chromatin remodeling complexes BAF and PBAF differentially regulate epigenetic transitions in exhausted CD8+ T cells

1
1. scibot 23 Jun 2023
  
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  DOI: 10.1016/j.immuni.2023.05.008
  
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sciencedirect.com/science/article/pii/S107476132300225X
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Intravenous heterologous prime-boost vaccination activates innate and adaptive immunity to promote tumor regression

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  DOI: 10.1016/j.celrep.2023.112599
  
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sciencedirect.com/science/article/pii/S2211124723006101
May 2023
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Tailoring vascular phenotype through AAV therapy promotes anti-tumor immunity in glioma

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1. scibot 12 May 2023
  
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  DOI: 10.1016/j.ccell.2023.04.010
  
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sciencedirect.com/science/article/pii/S1535610823001368
Apr 2023
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Lymphocyte networks are dynamic cellular communities in the immunoregulatory landscape of lung adenocarcinoma

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1. scibot 14 Apr 2023
  
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  DOI: 10.1016/j.ccell.2023.03.015
  
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sciencedirect.com/science/article/pii/S1535610823000880
Feb 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The altering cellular components and function in tumor microenvironment during remissive and relapsed stages of anti-CD19 CAR T-cell treated lymphoma mice

1
1. scibot 10 Feb 2023
  
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  DOI: 10.3389/fimmu.2023.1101769
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9905118/
Jan 2023
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MHC class II-restricted antigen presentation is required to prevent dysfunction of cytotoxic T cells by blood-borne myeloids in brain tumors

1
1. scibot 19 Jan 2023
  
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  DOI: 10.1016/j.ccell.2022.12.007
  
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sciencedirect.com/science/article/pii/S1535610822005931
Nov 2022
www.cell.com www.cell.com

Cancer immunotherapies transition endothelial cells into HEVs that generate TCF1+ T lymphocyte niches through a feed-forward loop

1
1. scibot 24 Nov 2022
  
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  DOI: 10.1016/j.ccell.2022.11.002
  
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cell.com/cancer-cell/fulltext/S1535-6108(22)00549-9
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CD8+ T cell metabolic rewiring defined by scRNA-seq identifies a critical role of ASNS expression dynamics in T cell differentiation

1
1. scibot 16 Nov 2022
  
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  DOI: 10.1016/j.celrep.2022.111639
  
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sciencedirect.com/science/article/pii/S2211124722015108
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Chronic type I interferon signaling promotes lipid-peroxidation-driven terminal CD8+ T cell exhaustion and curtails anti-PD-1 efficacy

1
1. scibot 16 Nov 2022
  
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  DOI: 10.1016/j.celrep.2022.111647
  
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sciencedirect.com/science/article/pii/S2211124722015182
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Cardiac myosin-specific autoimmune T cells contribute to immune-checkpoint-inhibitor-associated myocarditis

1
1. scibot 10 Nov 2022
  
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  DOI: 10.1016/j.celrep.2022.111611
  
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sciencedirect.com/science/article/pii/S2211124722014802
Oct 2022
www.cell.com www.cell.com

Systemic vaccination induces CD8+ T cells and remodels the tumor microenvironment

1
1. scibot 27 Oct 2022
  
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  DOI: 10.1016/j.cell.2022.10.006
  
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cell.com/cell/fulltext/S0092-8674(22)01321-6
52.53.155.43 52.53.155.43

IgA deficiency destabilizes immunological homeostasis towards intestinal microbiota and increases the risk of systemic immune dysregulation

1
1. scibot 27 Oct 2022
  
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  AB_2616907
  
  DOI: 10.1101/2021.08.20.21261620
  
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52.53.155.43/62b31cea1ac090bac2ebe32e4dfd3474fee27f84/2021.08.20.21261620v1.full-html.html
Jan 2022
www.nature.com www.nature.com

Adenosine 2A receptor and TIM3 suppress cytolytic killing of tumor cells via cytoskeletal polarization

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1. scibot 15 Jan 2022
  
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  RRID:AB_2616907
  
  DOI: 10.1038/s42003-021-02972-8
  
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nature.com/articles/s42003-021-02972-8
Sep 2021
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Antigen dominance hierarchies shape TCF1+ progenitor CD8 T cell phenotypes in tumors

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1. scibot 18 Sep 2021
  
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  DOI: 10.1016/j.cell.2021.08.020
  
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Conventional type I dendric cells maintain a reservoir of proliferative tumor-antigen specific TCF-1+ CD8+ T cells in tumor-draining lymph nodes

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1. scibot 17 Sep 2021
  
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  DOI: 10.1016/j.immuni.2021.08.026
  
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Aug 2021
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The CD155/TIGIT axis promotes and maintains immune evasion in neoantigen-expressing pancreatic cancer

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1. scibot 15 Aug 2021
  
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  DOI: 10.1016/j.ccell.2021.07.007
  
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CXCR6 positions cytotoxic T cells to receive critical survival signals in the tumor microenvironment

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1. scibot 15 Aug 2021
  
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  DOI: 10.1016/j.cell.2021.07.015
  
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sciencedirect.com/science/article/pii/S0092867421008564
Jul 2021
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Transforming growth factor-β-regulated mTOR activity preserves cellular metabolism to maintain long-term T cell responses in chronic infection

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1. scibot 07 Jul 2021
  
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  DOI: 10.1016/j.immuni.2021.06.007
  
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Apr 2021
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The PD-1/PD-L1-Checkpoint Restrains T cell Immunity in Tumor-Draining Lymph Nodes

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1. scibot 22 Apr 2021
  
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  DOI: 10.1016/j.ccell.2020.09.001
  
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UTX promotes CD8+ T cell-mediated antiviral defenses but reduces T cell durability

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1. scibot 15 Apr 2021
  
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  DOI: 10.1016/j.celrep.2021.108966
  
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In vivo CD8+ T cell CRISPR screening reveals control by Fli1 in infection and cancer

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1. scibot 11 Apr 2021
  
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  DOI: 10.1016/j.cell.2021.02.019
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8054351/
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Metabolic modulation by CDK4/6 inhibitor promotes chemokine-mediated recruitment of T cells into mammary tumors

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1. scibot 07 Apr 2021
  
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  DOI: 10.1016/j.celrep.2021.108944
  
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Sep 2020
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Developmental Relationships of Four Exhausted CD8+ T Cell Subsets Reveals Underlying Transcriptional and Epigenetic Landscape Control Mechanisms

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1. scibot 09 Sep 2020
  
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  DOI: 10.1016/j.immuni.2020.04.014
  
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The PD-1 Pathway Regulates Development and Function of Memory CD8+ T Cells following Respiratory Viral Infection

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1. scibot 04 Sep 2020
  
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  DOI: 10.1016/j.celrep.2020.107827
  
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Jan 2020
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TCF-1-Centered Transcriptional Network Drives an Effector versus Exhausted CD8 T Cell-Fate Decision

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.immuni.2019.09.013
  
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