65 Matching Annotations
  1. Last 7 days
  2. www.sciencedirect.com www.sciencedirect.com
    Profound synthetic lethality between SMARCAL1 and FANCM
    1
    1. scibot 17 Nov 2024
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      DOI: 10.1016/j.molcel.2024.10.016

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    sciencedirect.com/science/article/pii/S1097276524008566
  3. Nov 2024
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Kinesin-1 mediates proper ER folding of the CaV1.2 channel and maintains mouse glucose homeostasis
    1
    1. scibot 14 Nov 2024
      RRID:AB_2617116

      DOI: 10.1038/s44319-024-00246-y

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    pmc.ncbi.nlm.nih.gov/articles/PMC11549326/
  5. Oct 2024
  6. www.sciencedirect.com www.sciencedirect.com
    Inactive Parp2 causes Tp53-dependent lethal anemia by blocking replication-associated nick ligation in erythroblasts
    1
    1. scibot 09 Oct 2024
      AB_2617116

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    sciencedirect.com/science/article/pii/S1097276524007767
  7. Sep 2024
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Systems mapping of bidirectional endosomal transport through the crowded cell
    1
    1. scibot 17 Sep 2024
      AB_2617116

      DOI: 10.1016/j.cub.2024.08.026

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    ncbi.nlm.nih.gov/pmc/articles/PMC11466077/
  9. Jul 2024
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ttm50 facilitates calpain activation by anchoring it to calcium stores and increasing its sensitivity to calcium
    1
    1. scibot 18 Jul 2024
      RRID:AB_2617116

      DOI: 10.1038/s41422-020-0388-4

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    ncbi.nlm.nih.gov/pmc/articles/PMC8115179/
  11. www.biorxiv.org www.biorxiv.org
    Kinesin-1 mediates proper ER folding of the CaV1.2 channel and maintains mouse glucose homeostasis
    1
    1. scibot 04 Jul 2024
      RRID:AB_2617116

      DOI: 10.1101/2024.06.24.600327

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    biorxiv.org/content/10.1101/2024.06.24.600327v1
  12. Jun 2024
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ASAR lncRNAs control DNA replication timing through interactions with multiple hnRNP/RNA binding proteins
    1
    1. scibot 22 Jun 2024
      RRID:AB_2617116

      DOI: 10.7554/eLife.95898

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    ncbi.nlm.nih.gov/pmc/articles/PMC11186638/
  14. Apr 2024
  15. www.sciencedirect.com www.sciencedirect.com
    Oct4 controls basement membrane development during human embryogenesis
    1
    1. scibot 05 Apr 2024
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      DOI: 10.1016/j.devcel.2024.03.007

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    sciencedirect.com/science/article/pii/S1534580724001758
  16. Mar 2024
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The effects of Aurora Kinase inhibition on thyroid cancer growth and sensitivity to MAPK-directed therapies
    1
    1. scibot 27 Mar 2024
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      DOI: 10.1080/15384047.2024.2332000

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    ncbi.nlm.nih.gov/pmc/articles/PMC10962586/
  18. www.cell.com www.cell.com
    Myoglobin modulates the Hippo pathway to promote cardiomyocyte differentiation.
    3
    1. scibot 07 Mar 2024
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    2. scibot 07 Mar 2024
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      DOI: 10.1016/j.isci.2024.109146

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    3. scibot 02 Mar 2024
      RRID:AB_2617116

      DOI: 10.1016/j.isci.2024.109146

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    cell.com/iscience/abstract/S2589-0042(24)00367-5
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Fibronectin contributes to a BRAF inhibitor-driven invasive phenotype in thyroid cancer through EGR1, which can be blocked by inhibition of ERK1/2.
    1
    1. scibot 03 Mar 2024
      RRID:AB_2617116

      DOI: 10.1158/1541-7786.MCR-22-1031

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    ncbi.nlm.nih.gov/pmc/articles/PMC10524745/
  20. Feb 2024
  21. aacrjournals.org aacrjournals.org
    Nuclear GRP78 Promotes Metabolic Reprogramming and Therapeutic Resistance in Pancreatic Ductal Adenocarcinoma
    2
    1. scibot 23 Feb 2024
      RRID:AB_2617116

      DOI: 10.1158/1078-0432.CCR-23-1143

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      RRID:AB_2617116

      DOI: 10.1158/1078-0432.CCR-23-1143

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    aacrjournals.org/clincancerres/article/29/24/5183/731660/Nuclear-GRP78-Promotes-Metabolic-Reprogramming-and
  22. Dec 2023
  23. 52.53.155.43 52.53.155.43
    ccr-23-1143-html.html
    1
    1. scibot 01 Dec 2023
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      DOI: 10.1158/1078-0432.ccr-23-1143

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    52.53.155.43/aa509a782208f9df8c6754b69c5c07021388a9c4/ccr-23-1143-html.html
  24. Nov 2023
  25. www.sciencedirect.com www.sciencedirect.com
    Short salsalate administration affects cell proliferation, metabolism, and inflammation in polycystic kidney disease
    1
    1. scibot 29 Nov 2023
      RRID:AB_2617116

      DOI: 10.1016/j.isci.2023.108278

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    sciencedirect.com/science/article/pii/S2589004223023556
  26. www.sciencedirect.com www.sciencedirect.com
    Targeted perturbation of signaling-driven condensates
    1
    1. scibot 28 Nov 2023
      RRID:AB_2617116

      DOI: 10.1016/j.molcel.2023.10.023

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    sciencedirect.com/science/article/pii/S1097276523008602
  27. Oct 2023
  28. www.cell.com www.cell.com
    ATAC and SAGA co-activator complexes utilize co-translational assembly, but their cellular localization properties and functions are distinct
    1
    1. scibot 06 Oct 2023
      RRID:AB_2617116

      DOI: 10.1016/j.celrep.2023.113099

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    cell.com/cell-reports/abstract/S2211-1247(23)01110-5
  29. Sep 2023
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A twin UGUA motif directs the balance between gene isoforms through CFIm and the mTORC1 signaling pathway
    1
    1. scibot 06 Sep 2023
      RRID:AB_2617116

      DOI: 10.7554/eLife.85036

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    ncbi.nlm.nih.gov/pmc/articles/PMC10476966/
  31. Jul 2023
  32. www.sciencedirect.com www.sciencedirect.com
    The stability of the myelinating oligodendrocyte transcriptome is regulated by the nuclear lamina
    1
    1. scibot 29 Jul 2023
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      DOI: 10.1016/j.celrep.2023.112848

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    sciencedirect.com/science/article/pii/S2211124723008598
  33. www.sciencedirect.com www.sciencedirect.com
    Genome-scale mapping of DNA damage suppressors through phenotypic CRISPR-Cas9 screens
    1
    1. scibot 21 Jul 2023
      RRID:AB_2617116

      DOI: 10.1016/j.molcel.2023.06.025

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    sciencedirect.com/science/article/pii/S1097276523004720
  34. www.sciencedirect.com www.sciencedirect.com
    Length limitation of astral microtubules orients cell divisions in murine intestinal crypts
    1
    1. scibot 07 Jul 2023
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      DOI: 10.1016/j.devcel.2023.06.004

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    sciencedirect.com/science/article/abs/pii/S1534580723003027
  35. www.sciencedirect.com www.sciencedirect.com
    Oncogenic K-Ras suppresses global miRNA function
    1
    1. scibot 06 Jul 2023
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      DOI: 10.1016/j.molcel.2023.06.008

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    sciencedirect.com/science/article/pii/S109727652300429X
  36. Jun 2023
  37. www.sciencedirect.com www.sciencedirect.com
    The Rho1 GTPase controls anillo-septin assembly to facilitate contractile ring closure during cytokinesis
    1
    1. scibot 29 Jun 2023
      RRID:AB_2617116

      DOI: 10.1016/j.isci.2023.106903

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    sciencedirect.com/science/article/pii/S258900422300980X
  38. May 2023
  39. onlinelibrary.wiley.com onlinelibrary.wiley.com
    N-myc downstream regulated family member 1 (NDRG1) is enriched in myelinating oligodendrocytes and impacts myelin degradation in response to demyelination
    1
    1. scibot 05 May 2023
      CP06

      DOI: 10.1002/glia.24108

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    onlinelibrary.wiley.com/doi/full/10.1002/glia.24108
  40. Mar 2023
  41. www.sciencedirect.com www.sciencedirect.com
    HNRNPU facilitates antibody class-switch recombination through C-NHEJ promotion and R-loop suppression
    1
    1. scibot 23 Mar 2023
      RRID:AB_2617116

      DOI: 10.1016/j.celrep.2023.112284

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    sciencedirect.com/science/article/pii/S2211124723002954
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Harnessing transcriptionally driven chromosomal instability adaptation to target therapy-refractory lethal prostate cancer
    1
    1. scibot 04 Mar 2023
      RRID:AB_2617116

      DOI: 10.1016/j.xcrm.2023.100937

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    ncbi.nlm.nih.gov/pmc/articles/PMC9975292/
  43. www.sciencedirect.com www.sciencedirect.com
    Cyclin A and Cks1 promote kinase consensus switching to non-proline-directed CDK1 phosphorylation
    1
    1. scibot 03 Mar 2023
      RRID:AB_2617116

      DOI: 10.1016/j.celrep.2023.112139

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    sciencedirect.com/science/article/pii/S221112472300150X
  44. Feb 2023
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    KRAS Mutants Upregulate Integrin β4 to Promote Invasion and Metastasis in Colorectal Cancer
    1
    1. scibot 09 Feb 2023
      RRID:AB_2617116

      DOI: 10.1158/1541-7786.MCR-21-0994

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    ncbi.nlm.nih.gov/pmc/articles/PMC9357101/
  46. Oct 2022
  47. www.sciencedirect.com www.sciencedirect.com
    Circadian lncRNA ADIRF-AS1 binds PBAF and regulates renal clear cell tumorigenesis
    1
    1. scibot 20 Oct 2022
      RRID:AB_212802

      DOI: 10.1016/j.celrep.2022.111514

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    sciencedirect.com/science/article/pii/S221112472201364X
  48. Aug 2022
  49. www.sciencedirect.com www.sciencedirect.com
    METTL14-dependent m6A modification controls iNKT cell development and function
    1
    1. scibot 06 Aug 2022
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      DOI: 10.1016/j.celrep.2022.111156

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    sciencedirect.com/science/article/pii/S2211124722009652
  50. Jun 2022
  51. 52.53.155.43 52.53.155.43
    mcr-21-0994-html.html
    2
    1. scibot 30 Jun 2022
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      DOI: 10.1158/1541-7786.mcr-21-0994

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      RRID:AB_2617116

      DOI: 10.1158/1541-7786.mcr-21-0994

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    52.53.155.43/6cf2383cb2a91ee3aa464ebac45f324b39375a2a/mcr-21-0994 (1)-html.html
  52. www.sciencedirect.com www.sciencedirect.com
    Live imaging of Drosophila melanogaster neural stem cells with photo-ablated centrosomes
    1
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      DOI: 10.1016/j.xpro.2022.101493

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    sciencedirect.com/science/article/pii/S2666166722003732
  53. www.sciencedirect.com www.sciencedirect.com
    Dynamic rearrangement and autophagic degradation of mitochondria during spermiogenesis in the liverwort Marchantia polymorpha
    1
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      DOI: 10.1016/j.celrep.2022.110975

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    sciencedirect.com/science/article/pii/S2211124722007616
  54. Mar 2022
  55. www.sciencedirect.com www.sciencedirect.com
    A hotspot mutation targeting the R-RAS2 GTPase acts as a potent oncogenic driver in a wide spectrum of tumors
    1
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      DOI: 10.1016/j.celrep.2022.110522

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    sciencedirect.com/science/article/pii/S2211124722002583
  56. www.sciencedirect.com www.sciencedirect.com
    RIF1 acts in DNA repair through phosphopeptide recognition of 53BP1
    1
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      DOI: 10.1016/j.molcel.2022.01.025

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    sciencedirect.com/science/article/pii/S1097276522001010
  57. Jan 2022
  58. www.sciencedirect.com www.sciencedirect.com
    FGF1 and insulin control lipolysis by convergent pathways
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      DOI: 10.1016/j.cmet.2021.12.004

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    sciencedirect.com/science/article/pii/S1550413121006239
  59. Oct 2021
  60. www.sciencedirect.com www.sciencedirect.com
    Peripheral astral microtubules ensure asymmetric furrow positioning in neural stem cells
    1
    1. scibot 27 Oct 2021
      RRID:AB_2617116

      DOI: 10.1016/j.celrep.2021.109895

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    sciencedirect.com/science/article/pii/S2211124721013656
  61. www.sciencedirect.com www.sciencedirect.com
    Shift in MSL1 alternative polyadenylation in response to DNA damage protects cancer cells from chemotherapeutic agent-induced apoptosis
    1
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      DOI: 10.1016/j.celrep.2021.109815

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    sciencedirect.com/science/article/pii/S2211124721012791
  62. Sep 2021
  63. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Systemic inflammation induced the delayed reduction of excitatory synapses in the CA3 during ageing
    1
    1. scibot 30 Sep 2021
      RRID:AB_2617116

      DOI: 10.1111/jnc.15491

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    onlinelibrary.wiley.com/doi/10.1111/jnc.15491
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A molecular sensor determines the ubiquitin substrate specificity of SARS-CoV-2 papain-like protease
    1
    1. scibot 22 Sep 2021
      RRID:AB_2617116

      DOI: 10.1016/j.celrep.2021.109754

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    ncbi.nlm.nih.gov/pmc/articles/PMC8423903/
  65. Jul 2021
  66. www.sciencedirect.com www.sciencedirect.com
    Aster Proteins Facilitate Nonvesicular Plasma Membrane to ER Cholesterol Transport in Mammalian Cells
    1
    1. scibot 30 Jul 2021
      RRID:AB_2617116

      DOI: 10.1016/j.cell.2018.08.033

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    sciencedirect.com/science/article/pii/S0092867418310948
  67. www.sciencedirect.com www.sciencedirect.com
    IL-10 Signaling Remodels Adipose Chromatin Architecture to Limit Thermogenesis and Energy Expenditure
    1
    1. scibot 29 Jul 2021
      RRID:AB_2617116

      DOI: 10.1016/j.cell.2017.11.019

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    sciencedirect.com/science/article/pii/S0092867417313661
  68. May 2021
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Competitive coordination of the dual roles of the Hedgehog co-receptor in homophilic adhesion and signal reception
    1
    1. scibot 21 May 2021
      RRID:AB_2617116

      DOI: 10.7554/eLife.65770

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    ncbi.nlm.nih.gov/pmc/articles/PMC8131103/
  70. Apr 2021
  71. www.sciencedirect.com www.sciencedirect.com
    Mitochondria Define Intestinal Stem Cell Differentiation Downstream of a FOXO/Notch Axis
    1
    1. scibot 29 Apr 2021
      AB_2617116

      DOI: 10.1016/j.cmet.2020.10.005

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    sciencedirect.com/science/article/pii/S1550413120305386
  72. www.sciencedirect.com www.sciencedirect.com
    A Genetic Map of the Response to DNA Damage in Human Cells
    1
    1. scibot 23 Apr 2021
      Mouse monoclonal anti-α-tubilin

      DOI: 10.1016/j.cell.2020.05.040

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    sciencedirect.com/science/article/pii/S0092867420306735
  73. www.sciencedirect.com www.sciencedirect.com
    Cytoplasmic polyadenylation by TENT5A is required for proper bone formation
    1
    1. scibot 21 Apr 2021
      RRID:AB_2617116

      DOI: 10.1016/j.celrep.2021.109015

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    sciencedirect.com/science/article/pii/S2211124721003296
  74. Feb 2021
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ttm50 facilitates calpain activation by anchoring it to calcium stores and increasing its sensitivity to calcium
    1
    1. scibot 26 Feb 2021
      RRID:AB_2617116

      DOI: 10.1038/s41422-020-0388-4

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    ncbi.nlm.nih.gov/pmc/articles/PMC8115179/
  76. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Inhibition of BRAF and ERK1/2 has synergistic effects on thyroid cancer growth in vitro and in vivo
    1
    1. scibot 25 Feb 2021
      RRID:AB_2617116

      DOI: 10.1002/mc.23284

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    onlinelibrary.wiley.com/doi/full/10.1002/mc.23284
  77. www.cell.com www.cell.com
    Inverse Data-Driven Modeling and Multiomics Analysis Reveals Phgdh as a Metabolic Checkpoint of Macrophage Polarization and Proliferation
    1
    1. scibot 24 Feb 2021
      RRID:AB_2617116

      DOI: 10.1016/j.celrep.2020.01.011

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    cell.com/cell-reports/abstract/S2211-1247(20)30020-6
  78. Dec 2020
  79. www.cell.com www.cell.com
    Drosophila Tubulin-Specific Chaperone E Recruits Tubulin around Chromatin to Promote Mitotic Spindle Assembly
    1
    1. scibot 10 Dec 2020
      RRID:AB_2617116

      DOI: 10.1016/j.cub.2020.11.009

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    cell.com/current-biology/abstract/S0960-9822(20)31684-5
  80. Sep 2020
  81. www.sciencedirect.com www.sciencedirect.com
    LIN28B Underlies the Pathogenesis of a Subclass of Ewing Sarcoma LIN28B Control of EWS-FLI1 Stability
    1
    1. scibot 23 Sep 2020
      RRID:AB_2617116

      DOI: 10.1016/j.celrep.2019.12.053

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    sciencedirect.com/science/article/pii/S2211124719317103
  82. link.springer.com link.springer.com
    Novel HDAC inhibitor MAKV-8 and imatinib synergistically kill chronic myeloid leukemia cells via inhibition of BCR-ABL/MYC-signaling: effect on imatinib resistance and stem cells
    1
    1. scibot 16 Sep 2020
      RRID:AB_2617116

      DOI: 10.1186/s13148-020-00839-z

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    link.springer.com/article/10.1186/s13148-020-00839-z
  83. www.sciencedirect.com www.sciencedirect.com
    Neto-α Controls Synapse Organization and Homeostasis at the Drosophila Neuromuscular Junction
    1
    1. scibot 16 Sep 2020
      RRID:AB_2617116

      DOI: 10.1016/j.celrep.2020.107866

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    sciencedirect.com/science/article/pii/S2211124720308470
  84. Jan 2020
  85. www.sciencedirect.com www.sciencedirect.com
    MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis
    1
    1. scibot 13 Jan 2020
      RRID:AB_2617116

      DOI: 10.1016/j.molcel.2018.09.031

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    sciencedirect.com/science/article/pii/S1097276518308025
  86. Nov 2018
  87. www.sciencedirect.com www.sciencedirect.com
    The BRCT Domains of the BRCA1 and BARD1 Tumor Suppressors Differentially Regulate Homology-Directed Repair and Stalled Fork Protection
    1
    1. scibot 05 Nov 2018
      RRID:AB_2617116

      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S1097276518306762
  88. www.sciencedirect.com www.sciencedirect.com
    Nuclear Pores Promote Lethal Prostate Cancer by Increasing POM121-Driven E2F1, MYC, and AR Nuclear Import
    1
    1. scibot 05 Nov 2018
      RRID:AB_2617116

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    sciencedirect.com/science/article/pii/S0092867418309097
  89. www.sciencedirect.com www.sciencedirect.com
    Retrograde Degenerative Signaling Mediated by the p75 Neurotrophin Receptor Requires p150Glued Deacetylation by Axonal HDAC1
    1
    1. scibot 05 Nov 2018
      RRID:AB_2617116

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    sciencedirect.com/science/article/pii/S1534580718305549
  90. academic.oup.com academic.oup.com
    The Balance of PI3K and ERK Signaling Is Dysregulated in Prolactinoma and Modulated by Dopamine
    1
    1. scibot 05 Nov 2018
      RRID:AB_2617116

      Curator: @evieth

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    academic.oup.com/endo/article/159/6/2421/4990770
  91. www.sciencedirect.com www.sciencedirect.com
    An Acquired Vulnerability of Drug-Resistant Melanoma with Therapeutic Potential
    1
    1. scibot 05 Nov 2018
      RRID:AB_2617116

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    sciencedirect.com/science/article/pii/S0092867418305051
  92. europepmc.org europepmc.org
    A Paradoxical Tumor-Suppressor Role for the Rac1 Exchange Factor Vav1 in T Cell Acute Lymphoblastic Leukemia
    2
    1. scibot 05 Nov 2018
      RRID:AB_2617116

      Curator: @evieth

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      RRID:AB_2617116 RRIDCUR:Validated
    2. scibot 05 Nov 2018
      RRID:AB_2617116

      Curator: @evieth

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      (Millipore Cat# CP06, RRID:AB_2617116)

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    europepmc.org/articles/PMC5691892/
  93. Nov 2017
  94. www.sciencedirect.com www.sciencedirect.com
    Clock Regulation of Metabolites Reveals Coupling between Transcription and Metabolism
    1
    1. scibot 08 Nov 2017
      RRID:AB_2617116

      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S1550413117301717