Hypothesis

32 Matching Annotations

Dec 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

CDK2 inhibition enhances CDK4/6 inhibitor antitumor activity in comprehensive breast cancer PDX model screen

2
1. scibot 06 Dec 2025
  
  in Public
  
  RRID:AB_2617128
  
  DOI: 10.1038/s41523-025-00851-7
  
  Resource: (Cell Signaling Technology Cat# 8644, RRID:AB_2617128)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2617128
  
  What is this?
  
  RRID:AB_2617128
2. scibot 06 Dec 2025
  
  in Public
  
  RRID:AB_2617128
  
  DOI: 10.1038/s41523-025-00851-7
  
  Resource: (Cell Signaling Technology Cat# 8644, RRID:AB_2617128)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2617128
  
  What is this?
  
  RRID:AB_2617128
Visit annotations in context

Tags

RRID:AB_2617128

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12675586/
Nov 2025
www.sciencedirect.com www.sciencedirect.com

Co-targeting CDK4/6 enhances anti-cancer activity and alleviates immune-related adverse events of anti-PD-1 antibody for breast cancer

1
1. scibot 01 Nov 2025
  
  in Public
  
  RRID:AB_2617128
  
  DOI: 10.1016/j.xcrm.2025.102429
  
  Resource: (Cell Signaling Technology Cat# 8644, RRID:AB_2617128)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2617128
  
  What is this?
  
  RRID:AB_2617128
Visit annotations in context

Tags

RRID:AB_2617128

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2666379125005026
Aug 2025
www.science.org www.science.org

AND-1 is a critical regulator of R-loop dynamics and a target to overcome endocrine resistance

1
1. scibot 13 Aug 2025
  
  in Public
  
  RRID:AB_2617128
  
  DOI: 10.1126/sciadv.adv2453
  
  Resource: (Cell Signaling Technology Cat# 8644, RRID:AB_2617128)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2617128
  
  What is this?
  
  RRID:AB_2617128
Visit annotations in context

Tags

RRID:AB_2617128

Annotators

scibot

URL

science.org/doi/10.1126/sciadv.adv2453
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

AND-1 is a critical regulator of R-loop dynamics and a target to overcome endocrine resistance

1
1. scibot 12 Aug 2025
  
  in Public
  
  RRID:AB_2617128
  
  DOI: 10.1126/sciadv.adv2453
  
  Resource: (Cell Signaling Technology Cat# 8644, RRID:AB_2617128)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2617128
  
  What is this?
  
  RRID:AB_2617128
Visit annotations in context

Tags

RRID:AB_2617128

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12327453/
Jun 2025
www.sciencedirect.com www.sciencedirect.com

Combined inhibition of KAT6A/B and Menin reverses estrogen receptor-driven gene expression programs in breast cancer

1
1. scibot 14 Jun 2025
  
  in Public
  
  RRID:AB_2617128
  
  DOI: 10.1016/j.xcrm.2025.102192
  
  Resource: (Cell Signaling Technology Cat# 8644, RRID:AB_2617128)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2617128
  
  What is this?
  
  RRID:AB_2617128
Visit annotations in context

Tags

RRID:AB_2617128

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2666379125002654
May 2025
www.sciencedirect.com www.sciencedirect.com

Integrating reproductive states and social cues in the control of sociosexual behaviors

1
1. scibot 22 May 2025
  
  in Public
  
  RRID:AB_2617128
  
  DOI: 10.1016/j.cell.2025.04.035
  
  Resource: (Cell Signaling Technology Cat# 8644, RRID:AB_2617128)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2617128
  
  What is this?
  
  RRID:AB_2617128
Visit annotations in context

Tags

RRID:AB_2617128

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0092867425005057
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Interrogating Estrogen Signaling Pathways in Human ER-Positive Breast Cancer Cells Forming Bone Metastases in Mice

1
1. scibot 21 May 2025
  
  in Public
  
  RRID:AB_2617128
  
  DOI: 10.1210/endocr/bqae038
  
  Resource: (Cell Signaling Technology Cat# 8644, RRID:AB_2617128)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2617128
  
  What is this?
  
  RRID:AB_2617128
Visit annotations in context

Tags

RRID:AB_2617128

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC11076418/
Nov 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Glutamate Transport Proteins and Metabolic Enzymes are Poor Prognostic Factors in Invasive Lobular Carcinoma

1
1. scibot 07 Nov 2024
  
  in Public
  
  RRID:AB_2617128
  
  DOI: 10.1101/2024.09.29.615681
  
  Resource: (Cell Signaling Technology Cat# 8644, RRID:AB_2617128)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2617128
  
  What is this?
  
  RRID:AB_2617128
Visit annotations in context

Tags

RRID:AB_2617128

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC11507668/
Jun 2024
onlinelibrary.wiley.com onlinelibrary.wiley.com

Influence of intramuscular steroid receptor content and fiber capillarization on skeletal muscle hypertrophy

1
1. scibot 06 Jun 2024
  
  in Public
  
  RRID:AB_2617128
  
  DOI: 10.1111/sms.14668
  
  Resource: (Cell Signaling Technology Cat# 8644, RRID:AB_2617128)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2617128
  
  What is this?
  
  RRID:AB_2617128
Visit annotations in context

Tags

RRID:AB_2617128

Annotators

scibot

URL

onlinelibrary.wiley.com/doi/10.1111/sms.14668
physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com

Exercise training alters skeletal muscle microvascular endothelial cell properties in recent postmenopausal females

1
1. scibot 06 Jun 2024
  
  in Public
  
  RRID:AB_2617128
  
  DOI: 10.1113/JP286269
  
  Resource: (Cell Signaling Technology Cat# 8644, RRID:AB_2617128)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2617128
  
  What is this?
  
  RRID:AB_2617128
Visit annotations in context

Tags

RRID:AB_2617128

Annotators

scibot

URL

physoc.onlinelibrary.wiley.com/doi/10.1113/JP286269
www.sciencedirect.com www.sciencedirect.com

Nucleotide depletion promotes cell fate transitions by inducing DNA replication stress

1
1. scibot 04 Jun 2024
  
  in Public
  
  RRID:AB_2617128
  
  DOI: 10.1016/j.devcel.2024.05.010
  
  Resource: (Cell Signaling Technology Cat# 8644, RRID:AB_2617128)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2617128
  
  What is this?
  
  RRID:AB_2617128
Visit annotations in context

Tags

RRID:AB_2617128

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1534580724003277
Mar 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Liver Androgen Receptor Knockout Improved High-fat Diet Induced Glucose Dysregulation in Female Mice But Not Male Mice

1
1. scibot 03 Mar 2024
  
  in Public
  
  AB_2617128
  
  DOI: 10.1210/jendso/bvae021
  
  Resource: (Cell Signaling Technology Cat# 8644, RRID:AB_2617128)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2617128
  
  What is this?
  
  RRID:AB_2617128
Visit annotations in context

Tags

RRID:AB_2617128

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10904101/
Oct 2023
52.53.155.43 52.53.155.43

bqad159-html.html

1
1. scibot 31 Oct 2023
  
  in Public
  
  RRID:AB_2617128
  
  DOI: 10.1210/endocr/bqad159
  
  Resource: (Cell Signaling Technology Cat# 8644, RRID:AB_2617128)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2617128
  
  What is this?
  
  RRID:AB_2617128
Visit annotations in context

Tags

RRID:AB_2617128

Annotators

scibot

URL

52.53.155.43/fadb698104ccd541263e8069783171593188288f/bqad159-html.html
Aug 2023
www.biorxiv.org www.biorxiv.org

Unraveling Vulnerabilities in Endocrine Therapy-Resistant HER2+/ER+ Breast Cancer

1
1. scibot 27 Aug 2023
  
  in Public
  
  RRID:AB_2617128
  
  DOI: 10.1101/2023.08.21.554116
  
  Resource: (Cell Signaling Technology Cat# 8644, RRID:AB_2617128)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2617128
  
  What is this?
  
  RRID:AB_2617128
Visit annotations in context

Tags

RRID:AB_2617128

Annotators

scibot

URL

biorxiv.org/content/10.1101/2023.08.21.554116v1
Jun 2023
aacrjournals.org aacrjournals.org

Dysregulation of mitochondrial translation caused by CBFB deficiency cooperates with mutant PIK3CA and is a vulnerability in breast cancer

1
1. scibot 03 Jun 2023
  
  in Public
  
  RRID:AB_2617128
  
  DOI: 10.1158/0008-5472.CAN-22-2525
  
  Resource: (Cell Signaling Technology Cat# 8644, RRID:AB_2617128)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2617128
  
  What is this?
  
  RRID:AB_2617128
Visit annotations in context

Tags

RRID:AB_2617128

Annotators

scibot

URL

aacrjournals.org/cancerres/article/83/8/1280/725099/Dysregulation-of-Mitochondrial-Translation-Caused
Dec 2022
www.sciencedirect.com www.sciencedirect.com

AKTIP loss is enriched in ERα-positive breast cancer for tumorigenesis and confers endocrine resistance

1
1. scibot 18 Dec 2022
  
  in Public
  
  RRID:AB_2617128
  
  DOI: 10.1016/j.celrep.2022.111821
  
  Resource: (Cell Signaling Technology Cat# 8644, RRID:AB_2617128)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2617128
  
  What is this?
  
  RRID:AB_2617128
Visit annotations in context

Tags

RRID:AB_2617128

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124722017132
Jun 2022
www.sciencedirect.com www.sciencedirect.com

Evidence that HDAC7 acts as an epigenetic “reader” of AR acetylation through NCoR-HDAC3 dissociation

1
1. scibot 17 Jun 2022
  
  in Public
  
  RRID:AB_2617128
  
  DOI: 10.1016/j.chembiol.2022.05.008
  
  Resource: (Cell Signaling Technology Cat# 8644, RRID:AB_2617128)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2617128
  
  What is this?
  
  RRID:AB_2617128
Visit annotations in context

Tags

RRID:AB_2617128

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2451945622002008
Apr 2022
aacrjournals.org aacrjournals.org

Hotspot ESR1 mutations are multimodal and contextual modulators of breast cancer metastasis

1
1. scibot 05 Apr 2022
  
  in Public
  
  RRID:AB_2617128
  
  DOI: 10.1158/0008-5472.CAN-21-2576
  
  Resource: (Cell Signaling Technology Cat# 8644, RRID:AB_2617128)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2617128
  
  What is this?
  
  RRID:AB_2617128
Visit annotations in context

Tags

RRID:AB_2617128

Annotators

scibot

URL

aacrjournals.org/cancerres/article/82/7/1321/694048/Hotspot-ESR1-Mutations-Are-Multimodal-and
Mar 2022
www.sciencedirect.com www.sciencedirect.com

Inhibiting 3βHSD1 to eliminate the oncogenic effects of progesterone in prostate cancer

1
1. scibot 18 Mar 2022
  
  in Public
  
  RRID:AB_2617128
  
  DOI: 10.1016/j.xcrm.2022.100561
  
  Resource: (Cell Signaling Technology Cat# 8644, RRID:AB_2617128)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2617128
  
  What is this?
  
  RRID:AB_2617128
Visit annotations in context

Tags

RRID:AB_2617128

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2666379122000684
Feb 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Mediator of DNA damage checkpoint 1 (MDC1) is a novel estrogen receptor co-regulator in invasive lobular carcinoma of the breast

1
1. scibot 02 Feb 2022
  
  in Public
  
  RRID:AB_2617128
  
  DOI: 10.1158/1541-7786.MCR-21-0025
  
  Resource: (Cell Signaling Technology Cat# 8644, RRID:AB_2617128)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2617128
  
  What is this?
  
  RRID:AB_2617128
Visit annotations in context

Tags

RRID:AB_2617128

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC8349796/
Jan 2022
www.sciencedirect.com www.sciencedirect.com

Lineage-specific silencing of PSAT1 induces serine auxotrophy and sensitivity to dietary serine starvation in luminal breast tumors

1
1. scibot 19 Jan 2022
  
  in Public
  
  AB_2617128
  
  DOI: 10.1016/j.celrep.2021.110278
  
  Resource: (Cell Signaling Technology Cat# 8644, RRID:AB_2617128)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2617128
  
  What is this?
  
  RRID:AB_2617128
Visit annotations in context

Tags

RRID:AB_2617128

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124721017939
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Heat shock factor 1 (HSF1) cooperates with estrogen receptor α (ERα) in the regulation of estrogen action in breast cancer cells

1
1. scibot 07 Jan 2022
  
  in Public
  
  RRID:AB_2617128
  
  DOI: 10.7554/eLife.69843
  
  Resource: (Cell Signaling Technology Cat# 8644, RRID:AB_2617128)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2617128
  
  What is this?
  
  RRID:AB_2617128
Visit annotations in context

Tags

RRID:AB_2617128

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC8709578/
Sep 2021
www.sciencedirect.com www.sciencedirect.com

ERα is an RNA-binding protein sustaining tumor cell survival and drug resistance

1
1. scibot 24 Sep 2021
  
  in Public
  
  RRID:AB_2617128
  
  DOI: 10.1016/j.cell.2021.08.036
  
  Resource: (Cell Signaling Technology Cat# 8644, RRID:AB_2617128)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2617128
  
  What is this?
  
  RRID:AB_2617128
Visit annotations in context

Tags

RRID:AB_2617128

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0092867421010473
onlinelibrary.wiley.com onlinelibrary.wiley.com

Doxazosin and erlotinib have anticancer effects in the endometrial cancer cell and important roles in ERα and Wnt/β-catenin signaling pathways

1
1. scibot 04 Sep 2021
  
  in Public
  
  RRID: AB_2617128
  
  DOI: 10.1002/jbt.22905
  
  Resource: (Cell Signaling Technology Cat# 8644, RRID:AB_2617128)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2617128
  
  What is this?
  
  RRID:AB_2617128
Visit annotations in context

Tags

RRID:AB_2617128

Annotators

scibot

URL

onlinelibrary.wiley.com/doi/10.1002/jbt.22905
Aug 2021
academic.oup.com academic.oup.com

Differential Actions of Estrogen Receptor α and β via Non-Genomic Signaling in Human Prostate Stem and Progenitor Cells

1
1. scibot 05 Aug 2021
  
  in Public
  
  RRID:AB_2617128
  
  DOI: 10.1210/en.2019-00177
  
  Resource: (Cell Signaling Technology Cat# 8644, RRID:AB_2617128)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2617128
  
  What is this?
  
  RRID:AB_2617128
Visit annotations in context

Tags

RRID:AB_2617128

Annotators

scibot

URL

academic.oup.com/endo/article/160/11/2692/5551999
www.sciencedirect.com www.sciencedirect.com

KDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance

1
1. scibot 05 Aug 2021
  
  in Public
  
  RRID:AB_2617128
  
  DOI: 10.1016/j.ccell.2018.10.014
  
  Resource: (Cell Signaling Technology Cat# 8644, RRID:AB_2617128)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2617128
  
  What is this?
  
  RRID:AB_2617128
Visit annotations in context

Tags

RRID:AB_2617128

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S153561081830480X
Jul 2021
www.nature.com www.nature.com

Mitochondrial estrogen receptors alter mitochondrial priming and response to endocrine therapy in breast cancer cells

1
1. scibot 31 Jul 2021
  
  in Public
  
  8644
  
  DOI: 10.1038/s41420-021-00573-2
  
  Resource: (Cell Signaling Technology Cat# 8644, RRID:AB_2617128)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2617128
  
  What is this?
  
  RRID:AB_2617128 RRIDCUR:Missing
Visit annotations in context

Tags

RRIDCUR:Missing

RRID:AB_2617128

Annotators

scibot

URL

nature.com/articles/s41420-021-00573-2
Apr 2021
www.sciencedirect.com www.sciencedirect.com

FOXA1 Mutations Reveal Distinct Chromatin Profiles and Influence Therapeutic Response in Breast Cancer

1
1. scibot 22 Apr 2021
  
  in Public
  
  RRID:AB_2617128
  
  DOI: 10.1016/j.ccell.2020.08.003
  
  Resource: (Cell Signaling Technology Cat# 8644, RRID:AB_2617128)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2617128
  
  What is this?
  
  RRIDCUR:Validated RRID:AB_2617128
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_2617128

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1535610820304141
www.sciencedirect.com www.sciencedirect.com

The bone microenvironment increases phenotypic plasticity of ER+ breast cancer cells

1
1. scibot 20 Apr 2021
  
  in Public
  
  RRID:AB_2617128
  
  DOI: 10.1016/j.devcel.2021.03.008
  
  Resource: (Cell Signaling Technology Cat# 8644, RRID:AB_2617128)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2617128
  
  What is this?
  
  RRIDCUR:Validated RRID:AB_2617128
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_2617128

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1534580721002057
Sep 2020
www.sciencedirect.com www.sciencedirect.com

Neurofibromin Is an Estrogen Receptor-α Transcriptional Co-repressor in Breast Cancer

1
1. scibot 03 Sep 2020
  
  in Public
  
  RRID:AB_2617128
  
  DOI: 10.1016/j.ccell.2020.02.003
  
  Resource: (Cell Signaling Technology Cat# 8644, RRID:AB_2617128)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2617128
  
  What is this?
  
  RRID:AB_2617128 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_2617128

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1535610820300921
Jan 2020
www.sciencedirect.com www.sciencedirect.com

A Selective Ligand for Estrogen Receptor Proteins Discriminates Rapid and Genomic Signaling

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:AB_2617128
  
  DOI: 10.1016/j.chembiol.2019.10.009
  
  Resource: (Cell Signaling Technology Cat# 8644, RRID:AB_2617128)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2617128
  
  What is this?
  
  RRID:AB_2617128 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_2617128

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S245194561930354X