78 Matching Annotations
  1. Apr 2024
  2. www.embopress.org www.embopress.org
    PRODH safeguards human naive pluripotency by limiting mitochondrial oxidative phosphorylation and reactive oxygen species production
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    1. scibot 25 Apr 2024
      Cell signalingCat#12741;RRID:AB_2617131

      DOI: 10.1038/s44319-024-00110-z

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    2. scibot 18 Apr 2024
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    embopress.org/doi/full/10.1038/s44319-024-00110-z
  3. www.embopress.org www.embopress.org
    PRODH safeguards human naive pluripotency by limiting mitochondrial oxidative phosphorylation and reactive oxygen species production
    1
    1. scibot 25 Apr 2024
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    embopress.org/doi/10.1038/s44319-024-00110-z
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HDAC10 inhibition represses melanoma cell growth and BRAF inhibitor resistance via upregulating SPARC expression
    1
    1. scibot 24 Apr 2024
      RRID:AB_2617131

      DOI: 10.1093/narcan/zcae018

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    ncbi.nlm.nih.gov/pmc/articles/PMC11034028/
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Membrane-bound O-acyltransferase 7 (MBOAT7) shapes lysosomal lipid homeostasis and function to control alcohol-associated liver injury
    1
    1. scibot 24 Apr 2024
      RRID:AB_2617131

      DOI: 10.7554/eLife.92243

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    ncbi.nlm.nih.gov/pmc/articles/PMC11034944/
  6. www.sciencedirect.com www.sciencedirect.com
    Bacterial muropeptides promote OXPHOS and suppress mitochondrial stress in mammals
    1
    1. scibot 09 Apr 2024
      RRID:AB_2617131

      DOI: 10.1016/j.celrep.2024.114067

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    sciencedirect.com/science/article/pii/S2211124724003954
  7. Mar 2024
  8. www.sciencedirect.com www.sciencedirect.com
    Hepatic malonyl-CoA synthesis restrains gluconeogenesis by suppressing fat oxidation, pyruvate carboxylation, and amino acid availability
    2
    1. scibot 06 Mar 2024
      RRID:AB_2617131

      DOI: 10.1016/j.cmet.2024.02.004

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    2. scibot 06 Mar 2024
      RRID:AB_2617131

      DOI: 10.1016/j.cmet.2024.02.004

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    sciencedirect.com/science/article/pii/S1550413124000500
  9. Feb 2024
  10. www.sciencedirect.com www.sciencedirect.com
    hnRNPA2B1 represses the disassembly of arsenite-induced stress granules and is essential for male fertility
    1
    1. scibot 24 Feb 2024
      RRID:AB_2617131

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    sciencedirect.com/science/article/pii/S2211124724000974
  11. www.biorxiv.org www.biorxiv.org
    HDAC10 blockade upregulates SPARC expression thereby repressing melanoma cell growth and BRAF inhibitor resistance
    3
    1. scibot 09 Feb 2024
      RRID:AB_2617131

      DOI: 10.1101/2023.12.05.570182

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    2. scibot 09 Feb 2024
      RRID:AB_2617131

      DOI: 10.1101/2023.12.05.570182

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    3. scibot 09 Feb 2024
      RRID:AB_2617131

      DOI: 10.1101/2023.12.05.570182

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    biorxiv.org/content/10.1101/2023.12.05.570182v1
  12. Jan 2024
  13. www.sciencedirect.com www.sciencedirect.com
    A mitophagy sensor PPTC7 controls BNIP3 and NIX degradation to regulate mitochondrial mass
    2
    1. scibot 11 Jan 2024
      RRID:AB_2617131

      DOI: 10.1016/j.molcel.2023.11.038

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    2. scibot 11 Jan 2024
      RRID:AB_2617131

      DOI: 10.1016/j.molcel.2023.11.038

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    sciencedirect.com/science/article/pii/S1097276523010146
  14. www.sciencedirect.com www.sciencedirect.com
    Disruption of lysosomal nutrient sensing scaffold hyperactivates mTORC1 contributing to pathogenesis of a fatal neurodegenerative disease
    1
    1. scibot 11 Jan 2024
      RRID:AB_2617131

      DOI: 10.1016/j.jbc.2024.105641

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    sciencedirect.com/science/article/pii/S0021925824000176
  15. Nov 2023
  16. www.sciencedirect.com www.sciencedirect.com
    Nuclear localization of STING1 competes with canonical signaling to activate AHR for commensal and intestinal homeostasis
    1
    1. scibot 28 Nov 2023
      RRID:AB_2617131

      DOI: 10.1016/j.immuni.2023.11.001

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    sciencedirect.com/science/article/abs/pii/S1074761323004582
  17. www.sciencedirect.com www.sciencedirect.com
    E3 ligase Trim35 inhibits LSD1 demethylase activity through K63-linked ubiquitination and enhances anti-tumor immunity in NSCLC
    1
    1. scibot 22 Nov 2023
      RRID:AB_2617131

      DOI: 10.1016/j.celrep.2023.113477

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    sciencedirect.com/science/article/pii/S2211124723014894
  18. www.sciencedirect.com www.sciencedirect.com
    Skeletal muscle TFEB signaling promotes central nervous system function and reduces neuroinflammation during aging and neurodegenerative disease
    1
    1. scibot 17 Nov 2023
      RRID:AB_2617131

      DOI: 10.1016/j.celrep.2023.113436

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    sciencedirect.com/science/article/pii/S2211124723014481
  19. Oct 2023
  20. www.sciencedirect.com www.sciencedirect.com
    Blocking AMPKαS496 phosphorylation improves mitochondrial dynamics and hyperglycemia in aging and obesity
    1
    1. scibot 28 Oct 2023
      RRID:AB_2617131

      DOI: 10.1016/j.chembiol.2023.09.017

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    sciencedirect.com/science/article/pii/S2451945623003367
  21. www.science.org www.science.org
    Targeted BACE-1 inhibition in microglia enhances amyloid clearance and improved cognitive performance
    1
    1. scibot 17 Oct 2023
      AB_2617131

      DOI: 10.1126/sciadv.abo3610

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    science.org/doi/10.1126/sciadv.abo3610
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    S-acylation of p62 promotes p62 droplet recruitment into autophagosomes in mammalian autophagy
    1
    1. scibot 07 Oct 2023
      RRID:AB_2617131

      DOI: 10.1016/j.molcel.2023.09.004

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    ncbi.nlm.nih.gov/pmc/articles/PMC10552648/
  23. www.cell.com www.cell.com
    The heat shock protein Hsp27 controls mitochondrial function by modulating ceramide generation
    1
    1. scibot 06 Oct 2023
      RRID:AB_2617131

      DOI: 10.1016/j.celrep.2023.113081

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    cell.com/cell-reports/abstract/S2211-1247(23)01092-6
  24. 52.53.155.43 52.53.155.43
    BPS Publications
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    1. scibot 06 Oct 2023
      RRID:AB_2617131

      DOI: 10.1111/bph.16255

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    52.53.155.43/6079453bbbf12bd08872d5439d37d8b14bece994/British J Pharmacology - 2023 - Chen - DADLE promotes motor function recovery by inhibiting cytosolic phospholipase A2-html.html
  25. Aug 2023
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Autophagy ablation in skeletal muscles worsens sepsis-induced muscle wasting, impairs whole-body metabolism, and decreases survival.
    1
    1. scibot 19 Aug 2023
      RRID:AB_2617131

      DOI: 10.1016/j.isci.2023.107475

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    ncbi.nlm.nih.gov/pmc/articles/PMC10425945/
  27. www.sciencedirect.com www.sciencedirect.com
    The Hippo pathway noncanonically drives autophagy and cell survival in response to energy stress
    1
    1. scibot 18 Aug 2023
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      DOI: 10.1016/j.molcel.2023.07.019

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    sciencedirect.com/science/article/abs/pii/S1097276523005622
  28. Jul 2023
  29. 52.53.155.43 52.53.155.43
    SSRN-id4280868-html.html
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    1. scibot 26 Jul 2023
      RRID:AB_2617131

      DOI: 10.2139/ssrn.4280868

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    52.53.155.43/bfc43d0a34e11335a997ed0a27838b48307dddd9/SSRN-id4280868-html.html
  30. www.sciencedirect.com www.sciencedirect.com
    ALKBH5 causes retinal pigment epithelium anomalies and choroidal neovascularization in age-related macular degeneration via the AKT/mTOR pathway
    1
    1. scibot 13 Jul 2023
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      DOI: 10.1016/j.celrep.2023.112779

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    sciencedirect.com/science/article/pii/S2211124723007908
  31. Jun 2023
  32. 52.53.155.43 52.53.155.43
    SSRN-id4280868-html.html
    1
    1. scibot 30 Jun 2023
      RRID:AB_2617131

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  33. www.sciencedirect.com www.sciencedirect.com
    Advanced human iPSC-based preclinical model for Parkinson’s disease with optogenetic alpha-synuclein aggregation
    1
    1. scibot 21 Jun 2023
      RRID:AB_2617131

      DOI: 10.1016/j.stem.2023.05.015

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    sciencedirect.com/science/article/pii/S1934590923002114
  34. aacrjournals.org aacrjournals.org
    Dysregulation of mitochondrial translation caused by CBFB deficiency cooperates with mutant PIK3CA and is a vulnerability in breast cancer
    1
    1. scibot 03 Jun 2023
      RRID:AB_2617131

      DOI: 10.1158/0008-5472.CAN-22-2525

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    aacrjournals.org/cancerres/article/83/8/1280/725099/Dysregulation-of-Mitochondrial-Translation-Caused
  35. www.sciencedirect.com www.sciencedirect.com
    Cholesterol efflux pathways hinder KRAS-driven lung tumor progenitor cell expansion
    1
    1. scibot 02 Jun 2023
      RRID:AB_2617131

      DOI: 10.1016/j.stem.2023.05.005

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    sciencedirect.com/science/article/pii/S1934590923001753
  36. May 2023
  37. www.sciencedirect.com www.sciencedirect.com
    PROX1 induction by autolysosomal activity stabilizes persister-like state of colon cancer via feedback repression of the NOX1-mTORC1 pathway
    1
    1. scibot 24 May 2023
      RRID:AB_2617131

      DOI: 10.1016/j.celrep.2023.112519

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    sciencedirect.com/science/article/pii/S2211124723005302
  38. www.nature.com www.nature.com
    Restoration of lysosomal acidification rescues autophagy and metabolic dysfunction in non-alcoholic fatty liver disease
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    1. scibot 06 May 2023
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      DOI: 10.1038/s41467-023-38165-6

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    nature.com/articles/s41467-023-38165-6
  39. www.sciencedirect.com www.sciencedirect.com
    Dissecting the effects of GTPase and kinase domain mutations on LRRK2 endosomal localization and activity
    1
    1. scibot 04 May 2023
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      DOI: 10.1016/j.celrep.2023.112447

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    sciencedirect.com/science/article/pii/S2211124723004588
  40. Apr 2023
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Determination of the autophagic flux in murine and human peripheral blood mononuclear cells
    1
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      DOI: 10.3389/fcell.2023.1122998

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    ncbi.nlm.nih.gov/pmc/articles/PMC10040559/
  42. www.sciencedirect.com www.sciencedirect.com
    Myocardial structure and functional alterations in a preclinical model of exertional heat stroke
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      DOI: 10.1016/j.lfs.2023.121640

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    sciencedirect.com/science/article/pii/S0024320523002746
  43. Feb 2023
  44. link.springer.com link.springer.com
    Cold exposure alters lipid metabolism of skeletal muscle through HIF-1α-induced mitophagy
    1
    1. scibot 09 Feb 2023
      RRID:AB_2617131

      DOI: 10.1186/s12915-023-01514-4

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    link.springer.com/article/10.1186/s12915-023-01514-4
  45. Dec 2022
  46. www.sciencedirect.com www.sciencedirect.com
    Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis
    1
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      DOI: 10.1016/j.celrep.2022.111834

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    sciencedirect.com/science/article/pii/S2211124722017260
  47. www.sciencedirect.com www.sciencedirect.com
    USP32-regulated LAMTOR1 ubiquitination impacts mTORC1 activation and autophagy induction
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    1. scibot 08 Dec 2022
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      DOI: 10.1016/j.celrep.2022.111653

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    sciencedirect.com/science/article/pii/S2211124722015248
  48. Nov 2022
  49. www.sciencedirect.com www.sciencedirect.com
    Liver autophagy-induced valine and leucine in plasma reflect the metabolic effect of sodium glucose co-transporter 2 inhibitor dapagliflozin
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    1. scibot 22 Nov 2022
      RRID:AB_2617131

      DOI: 10.1016/j.ebiom.2022.104342

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    sciencedirect.com/science/article/pii/S2352396422005242
  50. Oct 2022
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SIRPα maintains macrophage homeostasis by interacting with PTK2B kinase in Mycobacterium tuberculosis infection and through autophagy and necroptosis
    1
    1. scibot 12 Oct 2022
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      DOI: 10.1016/j.ebiom.2022.104278

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    ncbi.nlm.nih.gov/pmc/articles/PMC9535427/
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sox9 mediates Autophagy-dependent vascular smooth muscle cell phenotypic modulation and transplant arteriosclerosis
    1
    1. scibot 07 Oct 2022
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      DOI: 10.1016/j.isci.2022.105161

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  53. Sep 2022
  54. www.sciencedirect.com www.sciencedirect.com
    PSMG2-controlled proteasome-autophagy balance mediates the tolerance for MEK-targeted therapy in triple-negative breast cancer
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  55. Aug 2022
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Glutamine metabolism modulates chondrocyte inflammatory response
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  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeted BACE-1 inhibition in microglia enhances amyloid clearance and improved cognitive performance
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  58. Jul 2022
  59. academic.oup.com academic.oup.com
    T cells mediate kidney tubular injury via impaired PDHA1 and Autophagy in type 1 diabetes
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      DOI: 10.1210/clinem/dgac378

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  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Upregulation of FOXO1 contributes to lipopolysaccharide-induced pulmonary endothelial injury by induction of autophagy
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  61. Mar 2022
  62. journals.lww.com journals.lww.com
    Urolithin A alleviates blood-brain barrier disruption and... : Neural Regeneration Research
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  63. Feb 2022
  64. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Autophagic and apoptotic cell death induced by the quinoline derivative 2-(6-methoxynaphthalen-2-yl)quinolin-4-amine in pancreatic cancer cells is via ER stress and inhibition of Akt/mTOR signaling pathway
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  65. Jan 2022
  66. link.springer.com link.springer.com
    Approaches and Protocols to Analyze Autophagy and Its Role in Death of Apoptosis-Resistant Senescent Tumor Cells
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  67. Dec 2021
  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Differential Autophagy Response in Men and Women After Muscle Damage
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  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Combined Inhibition of p38MAPK and PIKfyve Synergistically Disrupts Autophagy to Selectively Target Cancer Cells
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  70. Oct 2021
  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activation of mTORC1 and c-Jun by Prohibitin1 loss in Schwann cells may link mitochondrial dysfunction to demyelination
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  72. Sep 2021
  73. www.sciencedirect.com www.sciencedirect.com
    Roles of autophagy in relation to mitochondrial stress responses of HeLa cells to lamellarin cytotoxicity
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  74. Aug 2021
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Apocynin prevents cigarette smoking‐induced loss of skeletal muscle mass and function in mice by preserving proteostatic signalling
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  76. www.sciencedirect.com www.sciencedirect.com
    Regulation of UCP1 and Mitochondrial Metabolism in Brown Adipose Tissue by Reversible Succinylation
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  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genetically incorporated crosslinkers reveal NleE attenuates host autophagy dependent on PSMD10
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  78. Jul 2021
  79. www.sciencedirect.com www.sciencedirect.com
    Vangl2 limits chaperone-mediated autophagy to balance osteogenic differentiation in mesenchymal stem cells
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  80. Feb 2021
  81. www.mdpi.com www.mdpi.com
    Hyperthermia Increases Neurotoxicity Associated with Novel Methcathinones
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  82. link.springer.com link.springer.com
    Pancreatic beta cell autophagy is impaired in type 1 diabetes
    1
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      rabbit anti-LC3A/B

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  83. Jan 2021
  84. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Protective effect of hydrogen sulfide on endothelial cells through Sirt1-FoxO1-mediated autophagy
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  85. Sep 2020
  86. www.sciencedirect.com www.sciencedirect.com
    A FLCN-TFE3 Feedback Loop Prevents Excessive Glycogenesis and Phagocyte Activation by Regulating Lysosome Activity
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      DOI: 10.1016/j.celrep.2020.01.042

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  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Parkin contributes to synaptic vesicle autophagy in Bassoon-deficient mice
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  88. Jan 2020
  89. www.sciencedirect.com www.sciencedirect.com
    Hantavirus Inhibits TRAIL-Mediated Killing of Infected Cells by Downregulating Death Receptor 5
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      DOI: 10.1016/j.celrep.2019.07.066

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    RAD51AP1 Is an Essential Mediator of Alternative Lengthening of Telomeres
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      DOI: 10.1016/j.molcel.2019.06.043

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  91. www.frontiersin.org www.frontiersin.org
    Upregulated Expression of MicroRNA-204-5p Leads to the Death of Dopaminergic Cells by Targeting DYRK1A-Mediated Apoptotic Signaling Cascade
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      DOI: 10.3389/fncel.2019.00399

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    Non-oncogene Addiction to SIRT3 Plays a Critical Role in Lymphomagenesis
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  93. www.sciencedirect.com www.sciencedirect.com
    p53 Is a Master Regulator of Proteostasis in SMARCB1-Deficient Malignant Rhabdoid Tumors
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      RRID:AB_2617131

      DOI: 10.1016/j.ccell.2019.01.006

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  94. www.sciencedirect.com www.sciencedirect.com
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    Genetic Analysis Reveals AMPK Is Required to Support Tumor Growth in Murine Kras-Dependent Lung Cancer Models
    1
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      RRID:AB_2617131

      DOI: 10.1016/j.cmet.2018.10.005

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  96. Nov 2018
  97. academic.oup.com academic.oup.com
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    Mitofusin 2 Regulates Axonal Transport of Calpastatin to Prevent Neuromuscular Synaptic Elimination in Skeletal Muscles
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  99. onlinelibrary.wiley.com onlinelibrary.wiley.com
    The cardioprotective effect of thymoquinone on ischemia‐reperfusion injury in isolated rat heart via regulation of apoptosis and autophagy
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    Complement C3 Drives Autophagy-Dependent Restriction of Cyto-invasive Bacteria
    1
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  101. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of PIP4Kγ ameliorates the pathological effects of mutant huntingtin protein
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  103. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Chemoproteomic Approach to Query the Degradable Kinome Using a Multi-kinase Degrader
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