297 Matching Annotations
  1. Aug 2025
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    YTHDF proteins and m6A-RNA clients undergo autophagic turnover during contact inhibition
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    sciencedirect.com/science/article/pii/S2211124725009593
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    Conditional deletion of TRPC1 channel modulates synaptic plasticity, long term depression, and memory extinction in Fragile X Syndrome mice.
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    pmc.ncbi.nlm.nih.gov/articles/PMC12329558/
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    Inhibition of the minor spliceosome restricts the growth of a broad spectrum of cancers | EMBO reports
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    pmc.ncbi.nlm.nih.gov/articles/PMC12332006/
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    Assessing Determinants of Response to PARP Inhibition in Germline ATM Mutant Melanoma
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    mdpi.com/1422-0067/26/15/7420
  6. Jul 2025
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    ERRα and HIF-1α Cooperate to Enhance Breast Cancer Aggressiveness and Chemoresistance Under Hypoxic Conditions
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    mdpi.com/2072-6694/17/14/2382
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    BRAFV600E augments WNT signaling in colorectal cancer via aberrant DNA methylation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12272824/
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    Inhibition of the minor spliceosome restricts the growth of a broad spectrum of cancers
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    embopress.org/doi/10.1038/s44319-025-00511-8
  10. Jun 2025
  11. onlinelibrary.wiley.com onlinelibrary.wiley.com
    SOD1 Protein Content in Human Central Nervous System and Peripheral Tissues
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    onlinelibrary.wiley.com/doi/10.1111/jnc.70136
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    Integrin β6 expression in colorectal cancer cells promotes liver metastasis through enhanced adhesion to endothelial fibronectin
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    onlinelibrary.wiley.com/doi/10.1002/ijc.35504
  13. May 2025
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    Functional characterization of the ATOH1 molecular subtype indicates a pro-metastatic role in small cell lung cancer
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    sciencedirect.com/science/article/pii/S2211124725003742
  15. Apr 2025
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    A polytherapy approach demonstrates therapeutic efficacy for the treatment of SOD1 associated amyotrophic lateral sclerosis
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    sciencedirect.com/science/article/pii/S2352396425001367
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    Preventing and correcting polycystic ovary syndrome by targeting anti-Müllerian hormone signaling in minipuberty and adulthood in mice
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    Lysosome positioning affects NLRP3 inflammasome activation
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  20. Mar 2025
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    Realigned transsulfuration drives BRAF-V600E-targeted therapy resistance in melanoma
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    Hepatic stellate cells regulate liver fatty acid utilization via plasmalemma vesicle-associated protein
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  24. Feb 2025
  25. www.nature.com www.nature.com
    Structures of TGF-β with betaglycan and signaling receptors reveal mechanisms of complex assembly and signaling
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    nature.com/articles/s41467-025-56796-9
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    Custom affinity probes reveal DNA-damage-induced, ssDNA-independent chromatin SUMOylation in budding yeast
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  27. dx.doi.org dx.doi.org
    The deletion of nuclear progesterone receptors from kisspeptin cells does not impair negative feedback in female mice
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    dx.doi.org/10.1210/endocr/bqae121
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    The homologous recombination factors BRCA2 and PALB2 interplay with mismatch repair pathways to maintain centromere stability and cell viability
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  29. Jan 2025
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    Microvascular endothelial cells display organ-specific responses to extracellular matrix stiffness
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    Prolactin-mediates a lactation-induced suppression of arcuate kisspeptin neuronal activity necessary for lactational infertility in mice
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    elifesciences.org/articles/94570
  32. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Ovarian steroids modulate mRNA expression of ECM associated genes and collagen deposition induced by TGF β1 in equine endometrium in vitro
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    Functional Characteristics of the Crosstalk Between Vocal Fold Fibroblasts and Macrophages—The Role of Vibration in Vocal Fold Inflammation
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  36. Dec 2024
  37. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Modeling Drug Responses and Evolutionary Dynamics using Patient-Derived Xenografts Reveals Precision Medicine Strategies for Triple Negative Breast Cancer
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  38. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    An improved Erk biosensor detects oscillatory Erk dynamics driven by mitotic erasure during early development
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    CRL3ARMC5 ubiquitin ligase and Integrator phosphatase form parallel mechanisms to control early stages of RNA Pol II transcription
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  40. Nov 2024
  41. 52.53.155.43 52.53.155.43
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    PP2A licenses the FANCD2/FANCI complex for chromosome loading
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    Evidence for an interaction of paracingulin with microtubules
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  44. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Role of Membrane Estrogen Receptor Alpha on the Positive Feedback of Estrogens on Kisspeptin and GnRH Neurons
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  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chemogenetic activation of RFRP neurons reduces LH pulse frequency in female but not male mice
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  46. Oct 2024
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The androgen receptor in mesenchymal progenitors regulates skeletal muscle mass via Igf1 expression in male mice
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  48. Sep 2024
  49. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Amyloid beta 1-40 and 1-42 fibril ratios and maturation level cause conformational differences with minimal impact on autophagy and cytotoxicity
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    onlinelibrary.wiley.com/doi/10.1111/jnc.16201
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    Impaired cellular copper regulation in the presence of ApoE4
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  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ZEB1 Inhibits LHβ Subunit Transcription When Overexpressed, but Is Dispensable for LH Synthesis in Mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC11422717/
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mosaic ablation of pancreatic β cells induces de-differentiation and repetitive proliferation of residual β cells in adult mice
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    C2H2-zinc-finger transcription factors bind RNA and function in diverse post-transcriptional regulatory processes
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    Polyamines sustain epithelial regeneration in aged intestines by modulating protein homeostasis
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  56. Aug 2024
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    Human induced pluripotent stem cells for live cell cycle monitoring and endogenous gene activation
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    Septins promote macrophage pyroptosis by regulating gasdermin D cleavage and ninjurin-1-mediated plasma membrane rupture
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  59. dx.doi.org dx.doi.org
    The cullin Rtt101 promotes ubiquitin-dependent DNA−protein crosslink repair across the cell cycle
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    dx.doi.org/10.1093/nar/gkae658
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    PARG-deficient tumor cells have an increased dependence on EXO1/FEN1-mediated DNA repair
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  61. www.embopress.org www.embopress.org
    Cysteamine–bicalutamide combination therapy corrects proximal tubule phenotype in cystinosis
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    embopress.org/doi/full/10.15252/emmm.202013067
  62. Jul 2024
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    STAG2 mutations reshape the cohesin-structured spatial chromatin architecture to drive gene regulation in acute myeloid leukemia
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    Stress-dependent condensate formation regulated by the ubiquitin-related modifier Urm1
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    Human MC4R variants affect endocytosis, trafficking and dimerization revealing multiple cellular mechanisms involved in weight regulation
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  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Delivery of CDNF by AAV-mediated gene transfer protects dopamine neurons and regulates ER stress and inflammation in an acute MPTP mouse model of Parkinson’s disease
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    PP2A-B55 phosphatase counteracts Ki-67-dependent chromosome individualization during mitosis
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  68. Jun 2024
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    Bacterial esterases reverse lipopolysaccharide ubiquitylation to block host immunity
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  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Investigating GABA Neuron–Specific Androgen Receptor Knockout in two Hyperandrogenic Models of PCOS
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  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Oncogenic cell tagging and single-cell transcriptomics reveal cell type-specific and time-resolved responses to Vhl inactivation in the kidney
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    ncbi.nlm.nih.gov/pmc/articles/PMC11148546/
  72. May 2024
  73. www.sciencedirect.com www.sciencedirect.com
    A pseudoautosomal glycosylation disorder prompts the revision of dolichol biosynthesis
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    Quantitative proteomics reveals CLR interactome in primary human cells
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  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Patients and mice with deficiency in the SNARE protein SYNTAXIN-11 have a secondary B cell defect
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    Describing the Cellular Impact of IQOS™ Smoke Extract and Vibration on Human Vocal Fold Fibroblasts
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    Analysis of tumor-associated AXIN1 missense mutations identifies variants that activate β-catenin signaling
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    ncbi.nlm.nih.gov/pmc/articles/PMC11063763/
  79. Apr 2024
  80. www.sciencedirect.com www.sciencedirect.com
    Dopamine‑iron homeostasis interaction rescues mitochondrial fitness in Parkinson's disease
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    RAD52-dependent mitotic DNA synthesis is required for genome stability in Cyclin E1-overexpressing cells
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    PARG-deficient tumor cells have an increased dependence on EXO1/FEN1-mediated DNA repair
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    Compartmentalisation proteomics revealed endolysosomal protein network changes in a goat model of atrial fibrillation
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  84. Mar 2024
  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Drug-resistant EGFR mutations promote lung cancer by stabilizing interfaces in ligand-free kinase-active EGFR oligomers
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    Primary cilia as a tumor marker in pituitary neuroendocrine tumors
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    An early cell shape transition drives evolutionary expansion of the human forebrain
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  88. Feb 2024
  89. www.biorxiv.org www.biorxiv.org
    Dopamine-iron homeostasis interaction rescues mitochondrial fitness in Parkinson’s disease
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    Vocal fold fibroblasts and exposure to vibration in vitro: Does sex matter?
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    Brazilin is a natural product inhibitor of the NLRP3 inflammasome
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  94. genomebiology.biomedcentral.com genomebiology.biomedcentral.com
    The androgen receptor interacts with GATA3 to transcriptionally regulate a luminal epithelial cell phenotype in breast cancer
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    genomebiology.biomedcentral.com/articles/10.1186/s13059-023-03161-y
  95. Jan 2024
  96. www.sciencedirect.com www.sciencedirect.com
    EXO1 protects BRCA1-deficient cells against toxic DNA lesions
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    Structural basis for competitive binding of productive and degradative co-transcriptional effectors to the nuclear cap-binding complex
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    The phosphodiesterase 2A controls lymphatic junctional maturation via cGMP-dependent notch signaling
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  99. Dec 2023
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    One-pot trimodal mapping of unmethylated, hydroxymethylated, and open chromatin sites unveils distinctive 5hmC roles at dynamic chromatin loci
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  101. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ubiquiton—An inducible, linkage-specific polyubiquitylation tool
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    ncbi.nlm.nih.gov/pmc/articles/PMC10804999/
  102. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Brain proteome profiling implicates the complement and coagulation cascade in multiple system atrophy brain pathology
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    ncbi.nlm.nih.gov/pmc/articles/PMC9164190/
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    Generation of iPSC lines with SLC16A2:G401R or SLC16A2 knock out
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  104. Nov 2023
  105. www.nature.com www.nature.com
    Selective inhibition of CDK9 in triple negative breast cancer
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  189. Mar 2022
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  209. Oct 2021
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  214. Sep 2021
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