120 Matching Annotations
  1. Oct 2024
  2. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Transgenic sensors reveal compartment-specific effects of aggregation-prone proteins on subcellular proteostasis during aging
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    1. scibot 09 Oct 2024
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      DOI: 10.1016/j.crmeth.2024.100875

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    pubmed.ncbi.nlm.nih.gov/39383859/
  3. www.sciencedirect.com www.sciencedirect.com
    Leucine restriction ameliorates Fusobacterium nucleatum-driven malignant progression and radioresistance in nasopharyngeal carcinoma
    1
    1. scibot 02 Oct 2024
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      DOI: 10.1016/j.xcrm.2024.101753

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    sciencedirect.com/science/article/pii/S266637912400483X
  4. Sep 2024
  5. www.sciencedirect.com www.sciencedirect.com
    m6A mRNA methylation in brown fat regulates systemic insulin sensitivity via an inter-organ prostaglandin signaling axis independent of UCP1
    1
    1. scibot 10 Sep 2024
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      DOI: 10.1016/j.cmet.2024.08.006

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    sciencedirect.com/science/article/pii/S1550413124003334
  6. Aug 2024
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Protocol for transducing human primary epithelial prostate cells and patient-derived organoids with high efficiency
    1
    1. scibot 22 Aug 2024
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      DOI: 10.1016/j.xpro.2024.103200

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    ncbi.nlm.nih.gov/pmc/articles/PMC11315182/
  8. www.sciencedirect.com www.sciencedirect.com
    BDNF-dependent nano-organization of Neogenin and the WAVE Regulatory Complex promotes actin remodelling in dendritic spines
    1
    1. scibot 21 Aug 2024
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      DOI: 10.1016/j.isci.2024.110621

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    sciencedirect.com/science/article/pii/S2589004224018467
  9. Jul 2024
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Netrin signaling mediates survival of dormant epithelial ovarian cancer cells
    1
    1. scibot 20 Jul 2024
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      DOI: 10.7554/eLife.91766

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    ncbi.nlm.nih.gov/pmc/articles/PMC11257678/
  11. www.sciencedirect.com www.sciencedirect.com
    miRNA-mediated inhibition of an actomyosin network in hippocampal pyramidal neurons restricts sociability in adult male mice
    1
    1. scibot 18 Jul 2024
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      DOI: 10.1016/j.celrep.2024.114429

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    sciencedirect.com/science/article/pii/S2211124724007587
  12. www.cell.com www.cell.com
    Slc25a3-dependent copper transport controls flickering-induced Opa1 processing for mitochondrial safeguard
    1
    1. scibot 12 Jul 2024
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      DOI: 10.1016/j.devcel.2024.06.008

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    cell.com/developmental-cell/fulltext/S1534-5807(24)00386-1
  13. May 2024
  14. www.sciencedirect.com www.sciencedirect.com
    Star1 gene mutation reveals the essentiality of 11-ketotestosterone and glucocorticoids for male fertility in Nile Tilapia (Oreochromis niloticus)
    1
    1. scibot 25 May 2024
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      DOI: 10.1016/j.cbpb.2024.110985

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    sciencedirect.com/science/article/pii/S1096495924000526
  15. www.sciencedirect.com www.sciencedirect.com
    Targeting WEE1 enhances the antitumor effect of KRAS-mutated non-small cell lung cancer harboring TP53 mutations
    1
    1. scibot 23 May 2024
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      DOI: 10.1016/j.xcrm.2024.101578

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    sciencedirect.com/science/article/pii/S2666379124002702
  16. 52.53.155.43 52.53.155.43
    ol_28_1_14449_PDF-html.html
    1
    1. scibot 17 May 2024
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      DOI: 10.3892/ol.2024.14449

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  17. www.sciencedirect.com www.sciencedirect.com
    Obesity disrupts the pituitary-hepatic UPR communication leading to NAFLD progression
    1
    1. scibot 08 May 2024
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      DOI: 10.1016/j.cmet.2024.04.014

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    sciencedirect.com/science/article/pii/S1550413124001347
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Analysis of tumor-associated AXIN1 missense mutations identifies variants that activate β-catenin signaling
    1
    1. scibot 04 May 2024
      RRID:AB_2619646

      DOI: 10.1158/0008-5472.CAN-23-2268

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    ncbi.nlm.nih.gov/pmc/articles/PMC11063763/
  19. Apr 2024
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR-Cas9 screening identifies INTS3 as an anti-apoptotic RNA-binding protein and therapeutic target for colorectal cancer
    1
    1. scibot 28 Apr 2024
      RRID:AB_2619646

      DOI: 10.1016/j.isci.2024.109676

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    ncbi.nlm.nih.gov/pmc/articles/PMC11043890/
  21. www.sciencedirect.com www.sciencedirect.com
    RAD52-dependent mitotic DNA synthesis is required for genome stability in Cyclin E1-overexpressing cells
    2
    1. scibot 19 Apr 2024
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      DOI: 10.1016/j.celrep.2024.114116

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      DOI: 10.1016/j.celrep.2024.114116

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    sciencedirect.com/science/article/pii/S2211124724004443
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The role of RASA2 in predicting radioresistance in lung cancer through regulation of p53
    1
    1. scibot 11 Apr 2024
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      DOI: 10.21037/tlcr-24-160

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    ncbi.nlm.nih.gov/pmc/articles/PMC11002505/
  23. www.sciencedirect.com www.sciencedirect.com
    Central inhibition of HDAC6 re-sensitizes leptin signaling during obesity to induce profound weight loss
    1
    1. scibot 04 Apr 2024
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      DOI: 10.1016/j.cmet.2024.02.007

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    sciencedirect.com/science/article/pii/S1550413124000536
  24. Mar 2024
  25. www.sciencedirect.com www.sciencedirect.com
    Niche inflammatory signals control oscillating mammary regeneration and protect stem cells from cytotoxic stress
    1
    1. scibot 30 Mar 2024
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      DOI: 10.1016/j.stem.2023.11.012

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    sciencedirect.com/science/article/pii/S1934590923004290
  26. www.sciencedirect.com www.sciencedirect.com
    First-in-class MKK4 inhibitors enhance liver regeneration and prevent liver failure
    1
    1. scibot 19 Mar 2024
      RRID:AB_2619646

      DOI: 10.1016/j.cell.2024.02.023

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    sciencedirect.com/science/article/pii/S0092867424002253
  27. Jan 2024
  28. www.sciencedirect.com www.sciencedirect.com
    Hypoxia and intra-complex genetic suppressors rescue complex I mutants by a shared mechanism
    1
    1. scibot 18 Jan 2024
      RRID:AB_2619646

      DOI: 10.1016/j.cell.2023.12.010

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    sciencedirect.com/science/article/pii/S0092867423013429
  29. Nov 2023
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hippocampus Insulin Receptors Regulate Episodic and Spatial Memory Through Excitatory/Inhibitory Balance
    2
    1. scibot 09 Nov 2023
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      DOI: 10.1177/17590914231206657

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      DOI: 10.1177/17590914231206657

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    ncbi.nlm.nih.gov/pmc/articles/PMC10621302/
  31. www.sciencedirect.com www.sciencedirect.com
    Replicative stress in gastroesophageal premalignancy is associated with chromosomal instability and sensitivity to DNA damage response inhibitors
    1
    1. scibot 04 Nov 2023
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      DOI: 10.1016/j.isci.2023.108169

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    sciencedirect.com/science/article/pii/S2589004223022460
  32. Oct 2023
  33. www.sciencedirect.com www.sciencedirect.com
    Myotube growth is associated with cancer-like metabolic reprogramming and is limited by phosphoglycerate dehydrogenase
    1
    1. scibot 27 Oct 2023
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      DOI: 10.1016/j.yexcr.2023.113820

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    sciencedirect.com/science/article/pii/S0014482723003713
  34. www.science.org www.science.org
    Loss of function of the ALS-associated NEK1 kinase disrupts microtubule homeostasis and nuclear import
    1
    1. scibot 17 Oct 2023
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      DOI: 10.1126/sciadv.adi5548

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    science.org/doi/10.1126/sciadv.adi5548
  35. Sep 2023
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cryptotanshinone is a candidate therapeutic agent for interstitial lung disease associated with a BRICHOS-domain mutation of SFTPC
    1
    1. scibot 17 Sep 2023
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      DOI: 10.1016/j.isci.2023.107731

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    ncbi.nlm.nih.gov/pmc/articles/PMC10494175/
  37. Aug 2023
  38. www.science.org www.science.org
    Loss of function of the ALS-associated NEK1 kinase disrupts microtubule homeostasis and nuclear import
    1
    1. scibot 26 Aug 2023
      RRID:AB_2619646

      DOI: 10.1126/sciadv.adi5548

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    science.org/doi/10.1126/sciadv.adi5548
  39. www.sciencedirect.com www.sciencedirect.com
    Ets1 facilitates EMT/invasion through Drp1-mediated mitochondrial fragmentation in ovarian cancer
    1
    1. scibot 23 Aug 2023
      RRID:AB_2619646

      DOI: 10.1016/j.isci.2023.107537

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    sciencedirect.com/science/article/pii/S2589004223016140
  40. Jun 2023
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Glycolytic enzyme HK2 promotes PD-L1 expression and breast cancer cell immune evasion
    1
    1. scibot 30 Jun 2023
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      DOI: 10.3389/fimmu.2023.1189953

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    ncbi.nlm.nih.gov/pmc/articles/PMC10291184/
  42. www.sciencedirect.com www.sciencedirect.com
    An Epstein-Barr virus protein interaction map reveals NLRP3 inflammasome evasion via MAVS UFMylation
    1
    1. scibot 16 Jun 2023
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      DOI: 10.1016/j.molcel.2023.05.018

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    sciencedirect.com/science/article/pii/S109727652300374X
  43. May 2023
  44. www.sciencedirect.com www.sciencedirect.com
    Dissecting the effects of GTPase and kinase domain mutations on LRRK2 endosomal localization and activity
    1
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      DOI: 10.1016/j.celrep.2023.112447

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    sciencedirect.com/science/article/pii/S2211124723004588
  45. Apr 2023
  46. www.sciencedirect.com www.sciencedirect.com
    Targeting the mevalonate pathway suppresses ARID1A-inactivated cancers by promoting pyroptosis
    1
    1. scibot 19 Apr 2023
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      DOI: 10.1016/j.ccell.2023.03.002

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    sciencedirect.com/science/article/pii/S1535610823000508
  47. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Oncogene-mediated nuclear accumulation of lactate promotes epigenetic alterations to induce cancer cell proliferation
    1
    1. scibot 05 Apr 2023
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      DOI: 10.1002/jcb.30381

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    onlinelibrary.wiley.com/doi/10.1002/jcb.30381
  48. Feb 2023
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IGF-binding proteins secreted by cancer-associated fibroblasts induce context-dependent drug sensitization of lung cancer cells
    1
    1. scibot 17 Feb 2023
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      DOI: 10.1126/scisignal.abj5879

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    ncbi.nlm.nih.gov/pmc/articles/PMC9528501/
  50. Jan 2023
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Human Papillomavirus 42 Drives Digital Papillary Adenocarcinoma and Elicits a Germ Cell–like Program Conserved in HPV-Positive Cancers
    1
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      DOI: 10.1158/2159-8290.CD-22-0489

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    ncbi.nlm.nih.gov/pmc/articles/PMC9827110/
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Modulation of protease expression by the transcription factor Ptx1/PITX regulates protein quality control during aging
    1
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      DOI: 10.1016/j.celrep.2022.111970

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    ncbi.nlm.nih.gov/pmc/articles/PMC9933915/
  53. www.sciencedirect.com www.sciencedirect.com
    Progressive development of melanoma-induced cachexia differentially impacts organ systems in mice
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      DOI: 10.1016/j.celrep.2022.111934

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    sciencedirect.com/science/article/pii/S2211124722018356
  54. Dec 2022
  55. www.sciencedirect.com www.sciencedirect.com
    USP32-regulated LAMTOR1 ubiquitination impacts mTORC1 activation and autophagy induction
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      RRID:AB_2619646

      DOI: 10.1016/j.celrep.2022.111653

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    sciencedirect.com/science/article/pii/S2211124722015248
  56. Nov 2022
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    R-spondin 3 deletion induces Erk phosphorylation to enhance Wnt signaling and promote bone formation in the appendicular skeleton
    1
    1. scibot 30 Nov 2022
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      DOI: 10.7554/eLife.84171

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    ncbi.nlm.nih.gov/pmc/articles/PMC9681208/
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Parkinson’s disease-associated Leucine-rich repeat kinase regulates UNC-104-dependent axonal transport of Arl8-positive vesicles in Drosophila
    1
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    Improved recovery from skeletal muscle damage is largely unexplained by myofibrillar protein synthesis or inflammatory and regenerative gene expression pathways
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    Mutation of foxl2 or cyp19a1a Results in Female to Male Sex Reversal in XX Nile Tilapia
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  106. Jun 2021
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    Improved recovery from skeletal muscle damage is largely unexplained by myofibrillar protein synthesis or inflammatory and regenerative gene expression pathways
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    Stimulation of astrocytic sigma-1 receptor is sufficient to ameliorate inflammation- induced depression
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    G4C2 Repeat RNA Initiates a POM121-Mediated Reduction in Specific Nucleoporins in C9orf72 ALS/FTD
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    Hepatic Ago2 regulates PPARα for oxidative metabolism linked to glycemic control in obesity and post-bariatric surgery
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    Arctigenin protects against depression by inhibiting microglial activation and neuroinflammation via HMGB1/TLR4/NF‐κB and TNF‐α/TNFR1/NF‐κB pathways
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  124. Nov 2020
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  126. Oct 2020
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    The Lipid Handling Capacity of Subcutaneous Fat Is Programmed by mTORC2 during Development
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    Inhibition of astrocyte FAK–JNK signaling promotes subventricular zone neurogenesis through CNTF
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    11q Deletion or ALK Activity Curbs DLG2 Expression to Maintain an Undifferentiated State in Neuroblastoma
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    The Natural Compound Notopterol Binds and Targets JAK2/3 to Ameliorate Inflammation and Arthritis
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    Stromal cell-derived factor 1 (SDF1) attenuates platelet-derived growth factor-B (PDGF-B)-induced vascular remodeling for adipose tissue expansion in obesity
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    Methyl-Metabolite Depletion Elicits Adaptive Responses to Support Heterochromatin Stability and Epigenetic Persistence
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    Sleep deprivation regulates availability of PrPC and Aβ peptides which can impair interaction between PrPC and laminin and neuronal plasticity
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    Activation of astrocytic sigma‐1 receptor exerts antidepressant‐like effect via facilitating CD38‐driven mitochondria transfer
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    FSH-HIF-1α-VEGF pathway is critical for ovulation and oocyte health but not necessary for follicular growth in mice
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    Autophagic Degradation of NBR1 Restricts Metastatic Outgrowth during Mammary Tumor Progression
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  140. Jan 2020
  141. jcs.biologists.org jcs.biologists.org
    Blood vitronectin is a major activator of LIF and IL-6 in the brain through integrin–FAK and uPAR signaling
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    Non-canonical mTORC2 Signaling Regulates Brown Adipocyte Lipid Catabolism through SIRT6-FoxO1
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    Outcompeting p53-Mutant Cells in the Normal Esophagus by Redox Manipulation
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    Nicotinamide Pathway-Dependent Sirt1 Activation Restores Calcium Homeostasis to Achieve Neuroprotection in Spinocerebellar Ataxia Type 7
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    Suppressing Mitochondrial Respiration Is Critical for Hypoxia Tolerance in the Fetal Growth Plate
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    FGF15 Activates Hippo Signaling to Suppress Bile Acid Metabolism and Liver Tumorigenesis
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  148. Nov 2018
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    Tetracyclines Modify Translation by Targeting Key Human rRNA Substructures
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    FUS-induced neurotoxicity in Drosophila is prevented by downregulating nucleocytoplasmic transport proteinsHuman Molecular Genetics, 2018, Vol. 00, No. 0Human Molecular Genetics, 2018, Vol. 00, No. 0
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    LncRNA CamK-A Regulates Ca2+-Signaling-Mediated Tumor Microenvironment Remodeling
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  155. Nov 2017
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    β-TrCP1 Is a Vacillatory Regulator of Wnt Signaling
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    Hippo Signaling Suppresses Cell Ploidy and Tumorigenesis through Skp2
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    Lithocholic Acid Hydroxyamide Destabilizes Cyclin D1 and Induces G0/G1 Arrest by Inhibiting Deubiquitinase USP2a
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