106 Matching Annotations
  1. Apr 2024
  2. www.sciencedirect.com www.sciencedirect.com
    RAD52-dependent mitotic DNA synthesis is required for genome stability in Cyclin E1-overexpressing cells
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    1. scibot 19 Apr 2024
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      DOI: 10.1016/j.celrep.2024.114116

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      DOI: 10.1016/j.celrep.2024.114116

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    sciencedirect.com/science/article/pii/S2211124724004443
  3. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The role of RASA2 in predicting radioresistance in lung cancer through regulation of p53
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    1. scibot 11 Apr 2024
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      DOI: 10.21037/tlcr-24-160

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    ncbi.nlm.nih.gov/pmc/articles/PMC11002505/
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    Central inhibition of HDAC6 re-sensitizes leptin signaling during obesity to induce profound weight loss
    1
    1. scibot 04 Apr 2024
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      DOI: 10.1016/j.cmet.2024.02.007

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    sciencedirect.com/science/article/pii/S1550413124000536
  5. Mar 2024
  6. www.sciencedirect.com www.sciencedirect.com
    Niche inflammatory signals control oscillating mammary regeneration and protect stem cells from cytotoxic stress
    1
    1. scibot 30 Mar 2024
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      DOI: 10.1016/j.stem.2023.11.012

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    sciencedirect.com/science/article/pii/S1934590923004290
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    First-in-class MKK4 inhibitors enhance liver regeneration and prevent liver failure
    1
    1. scibot 19 Mar 2024
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      DOI: 10.1016/j.cell.2024.02.023

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    sciencedirect.com/science/article/pii/S0092867424002253
  8. Jan 2024
  9. www.sciencedirect.com www.sciencedirect.com
    Hypoxia and intra-complex genetic suppressors rescue complex I mutants by a shared mechanism
    1
    1. scibot 18 Jan 2024
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      DOI: 10.1016/j.cell.2023.12.010

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    sciencedirect.com/science/article/pii/S0092867423013429
  10. Nov 2023
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hippocampus Insulin Receptors Regulate Episodic and Spatial Memory Through Excitatory/Inhibitory Balance
    2
    1. scibot 09 Nov 2023
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      DOI: 10.1177/17590914231206657

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    2. scibot 09 Nov 2023
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      DOI: 10.1177/17590914231206657

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    ncbi.nlm.nih.gov/pmc/articles/PMC10621302/
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    Replicative stress in gastroesophageal premalignancy is associated with chromosomal instability and sensitivity to DNA damage response inhibitors
    1
    1. scibot 04 Nov 2023
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      DOI: 10.1016/j.isci.2023.108169

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    sciencedirect.com/science/article/pii/S2589004223022460
  13. Oct 2023
  14. www.sciencedirect.com www.sciencedirect.com
    Myotube growth is associated with cancer-like metabolic reprogramming and is limited by phosphoglycerate dehydrogenase
    1
    1. scibot 27 Oct 2023
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      DOI: 10.1016/j.yexcr.2023.113820

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    sciencedirect.com/science/article/pii/S0014482723003713
  15. www.science.org www.science.org
    Loss of function of the ALS-associated NEK1 kinase disrupts microtubule homeostasis and nuclear import
    1
    1. scibot 17 Oct 2023
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      DOI: 10.1126/sciadv.adi5548

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    science.org/doi/10.1126/sciadv.adi5548
  16. Sep 2023
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cryptotanshinone is a candidate therapeutic agent for interstitial lung disease associated with a BRICHOS-domain mutation of SFTPC
    1
    1. scibot 17 Sep 2023
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      DOI: 10.1016/j.isci.2023.107731

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    ncbi.nlm.nih.gov/pmc/articles/PMC10494175/
  18. Aug 2023
  19. www.science.org www.science.org
    Loss of function of the ALS-associated NEK1 kinase disrupts microtubule homeostasis and nuclear import
    1
    1. scibot 26 Aug 2023
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      DOI: 10.1126/sciadv.adi5548

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    science.org/doi/10.1126/sciadv.adi5548
  20. www.sciencedirect.com www.sciencedirect.com
    Ets1 facilitates EMT/invasion through Drp1-mediated mitochondrial fragmentation in ovarian cancer
    1
    1. scibot 23 Aug 2023
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      DOI: 10.1016/j.isci.2023.107537

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    sciencedirect.com/science/article/pii/S2589004223016140
  21. Jun 2023
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Glycolytic enzyme HK2 promotes PD-L1 expression and breast cancer cell immune evasion
    1
    1. scibot 30 Jun 2023
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      DOI: 10.3389/fimmu.2023.1189953

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    ncbi.nlm.nih.gov/pmc/articles/PMC10291184/
  23. www.sciencedirect.com www.sciencedirect.com
    An Epstein-Barr virus protein interaction map reveals NLRP3 inflammasome evasion via MAVS UFMylation
    1
    1. scibot 16 Jun 2023
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      DOI: 10.1016/j.molcel.2023.05.018

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    sciencedirect.com/science/article/pii/S109727652300374X
  24. May 2023
  25. www.sciencedirect.com www.sciencedirect.com
    Dissecting the effects of GTPase and kinase domain mutations on LRRK2 endosomal localization and activity
    1
    1. scibot 04 May 2023
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      DOI: 10.1016/j.celrep.2023.112447

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    sciencedirect.com/science/article/pii/S2211124723004588
  26. Apr 2023
  27. www.sciencedirect.com www.sciencedirect.com
    Targeting the mevalonate pathway suppresses ARID1A-inactivated cancers by promoting pyroptosis
    1
    1. scibot 19 Apr 2023
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      DOI: 10.1016/j.ccell.2023.03.002

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    sciencedirect.com/science/article/pii/S1535610823000508
  28. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Oncogene-mediated nuclear accumulation of lactate promotes epigenetic alterations to induce cancer cell proliferation
    1
    1. scibot 05 Apr 2023
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      DOI: 10.1002/jcb.30381

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    onlinelibrary.wiley.com/doi/10.1002/jcb.30381
  29. Feb 2023
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IGF-binding proteins secreted by cancer-associated fibroblasts induce context-dependent drug sensitization of lung cancer cells
    1
    1. scibot 17 Feb 2023
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      DOI: 10.1126/scisignal.abj5879

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    ncbi.nlm.nih.gov/pmc/articles/PMC9528501/
  31. Jan 2023
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Human Papillomavirus 42 Drives Digital Papillary Adenocarcinoma and Elicits a Germ Cell–like Program Conserved in HPV-Positive Cancers
    1
    1. scibot 15 Jan 2023
      RRID:AB_2619646

      DOI: 10.1158/2159-8290.CD-22-0489

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    ncbi.nlm.nih.gov/pmc/articles/PMC9827110/
  33. www.sciencedirect.com www.sciencedirect.com
    Modulation of protease expression by the transcription factor Ptx1/PITX regulates protein quality control during aging
    1
    1. scibot 12 Jan 2023
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      DOI: 10.1016/j.celrep.2022.111970

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    sciencedirect.com/science/article/pii/S2211124722018745
  34. www.sciencedirect.com www.sciencedirect.com
    Progressive development of melanoma-induced cachexia differentially impacts organ systems in mice
    1
    1. scibot 02 Jan 2023
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      DOI: 10.1016/j.celrep.2022.111934

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    sciencedirect.com/science/article/pii/S2211124722018356
  35. Dec 2022
  36. www.sciencedirect.com www.sciencedirect.com
    USP32-regulated LAMTOR1 ubiquitination impacts mTORC1 activation and autophagy induction
    1
    1. scibot 08 Dec 2022
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      DOI: 10.1016/j.celrep.2022.111653

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    sciencedirect.com/science/article/pii/S2211124722015248
  37. Nov 2022
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    R-spondin 3 deletion induces Erk phosphorylation to enhance Wnt signaling and promote bone formation in the appendicular skeleton
    1
    1. scibot 30 Nov 2022
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      DOI: 10.7554/eLife.84171

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    ncbi.nlm.nih.gov/pmc/articles/PMC9681208/
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Parkinson’s disease-associated Leucine-rich repeat kinase regulates UNC-104-dependent axonal transport of Arl8-positive vesicles in Drosophila
    1
    1. scibot 22 Nov 2022
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      DOI: 10.1016/j.isci.2022.105476

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    ncbi.nlm.nih.gov/pmc/articles/PMC9672966/
  40. rep.bioscientifica.com rep.bioscientifica.com
    Cholesterol supports bovine granulosa cell inflammatory responses to lipopolysaccharide
    1
    1. scibot 16 Nov 2022
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      DOI: 10.1530/REP-22-0032

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    rep.bioscientifica.com/view/journals/rep/164/3/REP-22-0032.xml
  41. www.sciencedirect.com www.sciencedirect.com
    Endothelial SIRT-1 has a critical role for the maintenance of capillarization in brown adipose tissue
    1
    1. scibot 10 Nov 2022
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      DOI: 10.1016/j.isci.2022.105424

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    sciencedirect.com/science/article/pii/S2589004222016960
  42. Oct 2022
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chemotherapeutic drug screening in 3D-Bioengineered human myobundles provides insight into taxane-induced myotoxicities
    1
    1. scibot 26 Oct 2022
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      DOI: 10.1016/j.isci.2022.105189

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    ncbi.nlm.nih.gov/pmc/articles/PMC9579017/
  44. Aug 2022
  45. www.sciencedirect.com www.sciencedirect.com
    An anillin-CIN85-SEPT9 complex promotes intercellular bridge maturation required for successful cytokinesis
    1
    1. scibot 31 Aug 2022
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      DOI: 10.1016/j.celrep.2022.111274

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    sciencedirect.com/science/article/pii/S2211124722010944
  46. www.sciencedirect.com www.sciencedirect.com
    Aerobic glycolysis promotes tumor immune evasion by hexokinase2-mediated phosphorylation of IκBα
    1
    1. scibot 25 Aug 2022
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      DOI: 10.1016/j.cmet.2022.08.002

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    sciencedirect.com/science/article/pii/S155041312200345X
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    LGP2 is essential for zebrafish survival through dual regulation of IFN antiviral response
    1
    1. scibot 10 Aug 2022
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      DOI: 10.1016/j.isci.2022.104821

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    sciencedirect.com/science/article/pii/S2589004222010938
  48. Jul 2022
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Manipulating bovine granulosa cell energy metabolism limits inflammation
    1
    1. scibot 14 Jul 2022
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      DOI: 10.1530/REP-20-0554

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    ncbi.nlm.nih.gov/pmc/articles/PMC9272410/
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    FKBP11 rewires UPR signaling to promote glucose homeostasis in type 2 diabetes and obesity
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    1. scibot 06 Jul 2022
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      DOI: 10.1016/j.cmet.2022.06.007

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    sciencedirect.com/science/article/pii/S1550413122002273
  51. Jun 2022
  52. www.sciencedirect.com www.sciencedirect.com
    Activation of STAT3 through combined SRC and EGFR signaling drives resistance to a mitotic kinesin inhibitor in glioblastoma
    1
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      DOI: 10.1016/j.celrep.2022.110991

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    sciencedirect.com/science/article/pii/S221112472200777X
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The SETDB1–TRIM28 complex suppresses antitumor immunity
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    1. scibot 07 Jun 2022
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      DOI: 10.1158/2326-6066.CIR-21-0754

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    ncbi.nlm.nih.gov/pmc/articles/PMC8647838/
  54. May 2022
  55. www.sciencedirect.com www.sciencedirect.com
    Differing impact of phosphoglycerate mutase 1-deficiency on brown and white adipose tissue
    1
    1. scibot 10 May 2022
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      DOI: 10.1016/j.isci.2022.104268

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    sciencedirect.com/science/article/pii/S2589004222005387
  56. Apr 2022
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SLC38A2 provides proline to fulfill unique synthetic demands arising during osteoblast differentiation and bone formation
    1
    1. scibot 15 Apr 2022
      RRID:AB_2619646

      DOI: 10.7554/eLife.76963

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    ncbi.nlm.nih.gov/pmc/articles/PMC9007586/
  58. Mar 2022
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Binding blockade between TLN1 and integrin β1 represses triple-negative breast cancer
    1
    1. scibot 26 Mar 2022
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      DOI: 10.7554/eLife.68481

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    ncbi.nlm.nih.gov/pmc/articles/PMC8937232/
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    Receptor tyrosine kinases regulate signal transduction through a liquid-liquid phase separated state
    1
    1. scibot 02 Mar 2022
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    11q Deletion or ALK Activity Curbs DLG2 Expression to Maintain an Undifferentiated State in Neuroblastoma
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    The Natural Compound Notopterol Binds and Targets JAK2/3 to Ameliorate Inflammation and Arthritis
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    Stromal cell-derived factor 1 (SDF1) attenuates platelet-derived growth factor-B (PDGF-B)-induced vascular remodeling for adipose tissue expansion in obesity
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    Methyl-Metabolite Depletion Elicits Adaptive Responses to Support Heterochromatin Stability and Epigenetic Persistence
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    Sleep deprivation regulates availability of PrPC and Aβ peptides which can impair interaction between PrPC and laminin and neuronal plasticity
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    Activation of astrocytic sigma‐1 receptor exerts antidepressant‐like effect via facilitating CD38‐driven mitochondria transfer
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    FSH-HIF-1α-VEGF pathway is critical for ovulation and oocyte health but not necessary for follicular growth in mice
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    Autophagic Degradation of NBR1 Restricts Metastatic Outgrowth during Mammary Tumor Progression
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  121. Jan 2020
  122. jcs.biologists.org jcs.biologists.org
    Blood vitronectin is a major activator of LIF and IL-6 in the brain through integrin–FAK and uPAR signaling
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      DOI: 10.1242/jcs.202580

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    Non-canonical mTORC2 Signaling Regulates Brown Adipocyte Lipid Catabolism through SIRT6-FoxO1
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    Outcompeting p53-Mutant Cells in the Normal Esophagus by Redox Manipulation
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    Nicotinamide Pathway-Dependent Sirt1 Activation Restores Calcium Homeostasis to Achieve Neuroprotection in Spinocerebellar Ataxia Type 7
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    Suppressing Mitochondrial Respiration Is Critical for Hypoxia Tolerance in the Fetal Growth Plate
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    FGF15 Activates Hippo Signaling to Suppress Bile Acid Metabolism and Liver Tumorigenesis
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  129. Nov 2018
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    Tetracyclines Modify Translation by Targeting Key Human rRNA Substructures
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    FUS-induced neurotoxicity in Drosophila is prevented by downregulating nucleocytoplasmic transport proteinsHuman Molecular Genetics, 2018, Vol. 00, No. 0Human Molecular Genetics, 2018, Vol. 00, No. 0
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    LncRNA CamK-A Regulates Ca2+-Signaling-Mediated Tumor Microenvironment Remodeling
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  135. nutritionandmetabolism.biomedcentral.com nutritionandmetabolism.biomedcentral.com
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  136. Nov 2017
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    β-TrCP1 Is a Vacillatory Regulator of Wnt Signaling
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    Hippo Signaling Suppresses Cell Ploidy and Tumorigenesis through Skp2
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    Lithocholic Acid Hydroxyamide Destabilizes Cyclin D1 and Induces G0/G1 Arrest by Inhibiting Deubiquitinase USP2a
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