115 Matching Annotations
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    Netrin signaling mediates survival of dormant epithelial ovarian cancer cells
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    1. scibot 20 Jul 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC11257678/
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    miRNA-mediated inhibition of an actomyosin network in hippocampal pyramidal neurons restricts sociability in adult male mice
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    1. scibot 18 Jul 2024
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    sciencedirect.com/science/article/pii/S2211124724007587
  4. Jul 2024
  5. www.cell.com www.cell.com
    Slc25a3-dependent copper transport controls flickering-induced Opa1 processing for mitochondrial safeguard
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    1. scibot 12 Jul 2024
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    cell.com/developmental-cell/abstract/S1534-5807(24)00386-1
  6. May 2024
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    Star1 gene mutation reveals the essentiality of 11-ketotestosterone and glucocorticoids for male fertility in Nile Tilapia (Oreochromis niloticus)
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    sciencedirect.com/science/article/pii/S1096495924000526
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    Targeting WEE1 enhances the antitumor effect of KRAS-mutated non-small cell lung cancer harboring TP53 mutations
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    1. scibot 23 May 2024
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    sciencedirect.com/science/article/pii/S2666379124002702
  9. 52.53.155.43 52.53.155.43
    ol_28_1_14449_PDF-html.html
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      DOI: 10.3892/ol.2024.14449

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    Obesity disrupts the pituitary-hepatic UPR communication leading to NAFLD progression
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    1. scibot 08 May 2024
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    sciencedirect.com/science/article/pii/S1550413124001347
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    Analysis of tumor-associated AXIN1 missense mutations identifies variants that activate β-catenin signaling
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    1. scibot 04 May 2024
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      DOI: 10.1158/0008-5472.CAN-23-2268

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    ncbi.nlm.nih.gov/pmc/articles/PMC11063763/
  12. Apr 2024
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR-Cas9 screening identifies INTS3 as an anti-apoptotic RNA-binding protein and therapeutic target for colorectal cancer
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    1. scibot 28 Apr 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC11043890/
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    RAD52-dependent mitotic DNA synthesis is required for genome stability in Cyclin E1-overexpressing cells
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    sciencedirect.com/science/article/pii/S2211124724004443
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    The role of RASA2 in predicting radioresistance in lung cancer through regulation of p53
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    1. scibot 11 Apr 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC11002505/
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    Central inhibition of HDAC6 re-sensitizes leptin signaling during obesity to induce profound weight loss
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    sciencedirect.com/science/article/pii/S1550413124000536
  17. Mar 2024
  18. www.sciencedirect.com www.sciencedirect.com
    Niche inflammatory signals control oscillating mammary regeneration and protect stem cells from cytotoxic stress
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    1. scibot 30 Mar 2024
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      DOI: 10.1016/j.stem.2023.11.012

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    sciencedirect.com/science/article/pii/S1934590923004290
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    First-in-class MKK4 inhibitors enhance liver regeneration and prevent liver failure
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    1. scibot 19 Mar 2024
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    sciencedirect.com/science/article/pii/S0092867424002253
  20. Jan 2024
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    Hypoxia and intra-complex genetic suppressors rescue complex I mutants by a shared mechanism
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    1. scibot 18 Jan 2024
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    sciencedirect.com/science/article/pii/S0092867423013429
  22. Nov 2023
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hippocampus Insulin Receptors Regulate Episodic and Spatial Memory Through Excitatory/Inhibitory Balance
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    ncbi.nlm.nih.gov/pmc/articles/PMC10621302/
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    Replicative stress in gastroesophageal premalignancy is associated with chromosomal instability and sensitivity to DNA damage response inhibitors
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      DOI: 10.1016/j.isci.2023.108169

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    sciencedirect.com/science/article/pii/S2589004223022460
  25. Oct 2023
  26. www.sciencedirect.com www.sciencedirect.com
    Myotube growth is associated with cancer-like metabolic reprogramming and is limited by phosphoglycerate dehydrogenase
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    sciencedirect.com/science/article/pii/S0014482723003713
  27. www.science.org www.science.org
    Loss of function of the ALS-associated NEK1 kinase disrupts microtubule homeostasis and nuclear import
    1
    1. scibot 17 Oct 2023
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      DOI: 10.1126/sciadv.adi5548

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    science.org/doi/10.1126/sciadv.adi5548
  28. Sep 2023
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cryptotanshinone is a candidate therapeutic agent for interstitial lung disease associated with a BRICHOS-domain mutation of SFTPC
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    1. scibot 17 Sep 2023
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    ncbi.nlm.nih.gov/pmc/articles/PMC10494175/
  30. Aug 2023
  31. www.science.org www.science.org
    Loss of function of the ALS-associated NEK1 kinase disrupts microtubule homeostasis and nuclear import
    1
    1. scibot 26 Aug 2023
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      DOI: 10.1126/sciadv.adi5548

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    science.org/doi/10.1126/sciadv.adi5548
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    Ets1 facilitates EMT/invasion through Drp1-mediated mitochondrial fragmentation in ovarian cancer
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    sciencedirect.com/science/article/pii/S2589004223016140
  33. Jun 2023
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Glycolytic enzyme HK2 promotes PD-L1 expression and breast cancer cell immune evasion
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    ncbi.nlm.nih.gov/pmc/articles/PMC10291184/
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    An Epstein-Barr virus protein interaction map reveals NLRP3 inflammasome evasion via MAVS UFMylation
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    sciencedirect.com/science/article/pii/S109727652300374X
  36. May 2023
  37. www.sciencedirect.com www.sciencedirect.com
    Dissecting the effects of GTPase and kinase domain mutations on LRRK2 endosomal localization and activity
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      DOI: 10.1016/j.celrep.2023.112447

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    sciencedirect.com/science/article/pii/S2211124723004588
  38. Apr 2023
  39. www.sciencedirect.com www.sciencedirect.com
    Targeting the mevalonate pathway suppresses ARID1A-inactivated cancers by promoting pyroptosis
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      DOI: 10.1016/j.ccell.2023.03.002

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    sciencedirect.com/science/article/pii/S1535610823000508
  40. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Oncogene-mediated nuclear accumulation of lactate promotes epigenetic alterations to induce cancer cell proliferation
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      DOI: 10.1002/jcb.30381

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    onlinelibrary.wiley.com/doi/10.1002/jcb.30381
  41. Feb 2023
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IGF-binding proteins secreted by cancer-associated fibroblasts induce context-dependent drug sensitization of lung cancer cells
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      DOI: 10.1126/scisignal.abj5879

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    ncbi.nlm.nih.gov/pmc/articles/PMC9528501/
  43. Jan 2023
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Human Papillomavirus 42 Drives Digital Papillary Adenocarcinoma and Elicits a Germ Cell–like Program Conserved in HPV-Positive Cancers
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      DOI: 10.1158/2159-8290.CD-22-0489

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    ncbi.nlm.nih.gov/pmc/articles/PMC9827110/
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Modulation of protease expression by the transcription factor Ptx1/PITX regulates protein quality control during aging
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      DOI: 10.1016/j.celrep.2022.111970

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    ncbi.nlm.nih.gov/pmc/articles/PMC9933915/
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    Progressive development of melanoma-induced cachexia differentially impacts organ systems in mice
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    sciencedirect.com/science/article/pii/S2211124722018356
  47. Dec 2022
  48. www.sciencedirect.com www.sciencedirect.com
    USP32-regulated LAMTOR1 ubiquitination impacts mTORC1 activation and autophagy induction
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      DOI: 10.1016/j.celrep.2022.111653

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    sciencedirect.com/science/article/pii/S2211124722015248
  49. Nov 2022
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    R-spondin 3 deletion induces Erk phosphorylation to enhance Wnt signaling and promote bone formation in the appendicular skeleton
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      DOI: 10.7554/eLife.84171

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    ncbi.nlm.nih.gov/pmc/articles/PMC9681208/
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Parkinson’s disease-associated Leucine-rich repeat kinase regulates UNC-104-dependent axonal transport of Arl8-positive vesicles in Drosophila
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      DOI: 10.1016/j.isci.2022.105476

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    ncbi.nlm.nih.gov/pmc/articles/PMC9672966/
  52. rep.bioscientifica.com rep.bioscientifica.com
    Cholesterol supports bovine granulosa cell inflammatory responses to lipopolysaccharide
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      DOI: 10.1530/REP-22-0032

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    rep.bioscientifica.com/view/journals/rep/164/3/REP-22-0032.xml
  53. www.sciencedirect.com www.sciencedirect.com
    Endothelial SIRT-1 has a critical role for the maintenance of capillarization in brown adipose tissue
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      DOI: 10.1016/j.isci.2022.105424

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    sciencedirect.com/science/article/pii/S2589004222016960
  54. Oct 2022
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chemotherapeutic drug screening in 3D-Bioengineered human myobundles provides insight into taxane-induced myotoxicities
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      DOI: 10.1016/j.isci.2022.105189

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    ncbi.nlm.nih.gov/pmc/articles/PMC9579017/
  56. Aug 2022
  57. www.sciencedirect.com www.sciencedirect.com
    An anillin-CIN85-SEPT9 complex promotes intercellular bridge maturation required for successful cytokinesis
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      DOI: 10.1016/j.celrep.2022.111274

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    sciencedirect.com/science/article/pii/S2211124722010944
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    Aerobic glycolysis promotes tumor immune evasion by hexokinase2-mediated phosphorylation of IκBα
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    G4C2 Repeat RNA Initiates a POM121-Mediated Reduction in Specific Nucleoporins in C9orf72 ALS/FTD
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    Glutamine deficiency promotes stemness and chemoresistance in tumor cells through DRP1-induced mitochondrial fragmentation
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  114. Feb 2021
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    Hepatic Ago2 regulates PPARα for oxidative metabolism linked to glycemic control in obesity and post-bariatric surgery
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    Arctigenin protects against depression by inhibiting microglial activation and neuroinflammation via HMGB1/TLR4/NF‐κB and TNF‐α/TNFR1/NF‐κB pathways
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  117. Nov 2020
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  119. Oct 2020
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    Quantitative Proteomics Analysis of Lytic KSHV Infection in Human Endothelial Cells Reveals Targets of Viral Immune Modulation
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  121. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    The Lipid Handling Capacity of Subcutaneous Fat Is Programmed by mTORC2 during Development
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  122. Sep 2020
  123. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Inhibition of astrocyte FAK–JNK signaling promotes subventricular zone neurogenesis through CNTF
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    Transcriptomic and proteomic landscape of mitochondrial dysfunction reveals secondary coenzyme Q deficiency in mammals
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    11q Deletion or ALK Activity Curbs DLG2 Expression to Maintain an Undifferentiated State in Neuroblastoma
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    The Natural Compound Notopterol Binds and Targets JAK2/3 to Ameliorate Inflammation and Arthritis
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    Stromal cell-derived factor 1 (SDF1) attenuates platelet-derived growth factor-B (PDGF-B)-induced vascular remodeling for adipose tissue expansion in obesity
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    Methyl-Metabolite Depletion Elicits Adaptive Responses to Support Heterochromatin Stability and Epigenetic Persistence
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    Sleep deprivation regulates availability of PrPC and Aβ peptides which can impair interaction between PrPC and laminin and neuronal plasticity
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    Activation of astrocytic sigma‐1 receptor exerts antidepressant‐like effect via facilitating CD38‐driven mitochondria transfer
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    FSH-HIF-1α-VEGF pathway is critical for ovulation and oocyte health but not necessary for follicular growth in mice
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    Autophagic Degradation of NBR1 Restricts Metastatic Outgrowth during Mammary Tumor Progression
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  133. Jan 2020
  134. jcs.biologists.org jcs.biologists.org
    Blood vitronectin is a major activator of LIF and IL-6 in the brain through integrin–FAK and uPAR signaling
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      DOI: 10.1242/jcs.202580

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    Non-canonical mTORC2 Signaling Regulates Brown Adipocyte Lipid Catabolism through SIRT6-FoxO1
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    Outcompeting p53-Mutant Cells in the Normal Esophagus by Redox Manipulation
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      DOI: 10.1016/j.stem.2019.06.011

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    Nicotinamide Pathway-Dependent Sirt1 Activation Restores Calcium Homeostasis to Achieve Neuroprotection in Spinocerebellar Ataxia Type 7
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    Suppressing Mitochondrial Respiration Is Critical for Hypoxia Tolerance in the Fetal Growth Plate
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    FGF15 Activates Hippo Signaling to Suppress Bile Acid Metabolism and Liver Tumorigenesis
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  141. Nov 2018
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    Tetracyclines Modify Translation by Targeting Key Human rRNA Substructures
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  143. academic.oup.com academic.oup.com
    FUS-induced neurotoxicity in Drosophila is prevented by downregulating nucleocytoplasmic transport proteinsHuman Molecular Genetics, 2018, Vol. 00, No. 0Human Molecular Genetics, 2018, Vol. 00, No. 0
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    LncRNA CamK-A Regulates Ca2+-Signaling-Mediated Tumor Microenvironment Remodeling
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  147. nutritionandmetabolism.biomedcentral.com nutritionandmetabolism.biomedcentral.com
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  148. Nov 2017
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    β-TrCP1 Is a Vacillatory Regulator of Wnt Signaling
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    Hippo Signaling Suppresses Cell Ploidy and Tumorigenesis through Skp2
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    Lithocholic Acid Hydroxyamide Destabilizes Cyclin D1 and Induces G0/G1 Arrest by Inhibiting Deubiquitinase USP2a
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