355 Matching Annotations
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    KDM6A loss enhances oxidative phosphorylation uncovering tissue-level convergent evolution
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    link.springer.com/article/10.1038/s44318-026-00891-0
  3. Aug 2026
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    Antenatal Hypoxia and Dexamethasone Independently Alter Hepatic Cytochrome P450 Activity and Glucocorticoid Receptor Isoform Cellular Localisation in Ovine Offspring
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    UV irradiation drives lineage-specific MITF-mediated transcription of PD-L1 to confer immune tolerance to UV-mutated melanocytes
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    sciencedirect.com/science/article/pii/S1074761326003171
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    FOXA1 drives chemoresistance through activating Wnt pathway in small cell lung cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13458387/
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    Senescent microglia with shortened telomeres secrete soluble DLK1 to induce aging-associated hypomyelination and neuronal dysfunction
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    sciencedirect.com/science/article/pii/S0896627326005775
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    Phosphoproteomic profiling reveals post-translational dysregulation in Huntington’s disease patient-derived neurons
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  10. Jul 2026
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    NaHS replenishes hydrogen sulfide levels and rescues myelination defects through NRF2 signaling and iron homeostasis after traumatic brain injury in Swiss albino male mice
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    Cdk7 promotes neuritogenesis in cortical neurons and contributes to social behavior in mice
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    Antibody-Mediated Targeting of Secretory Protein SCUBE3 Suppresses Cancer Progression by Inhibiting Oncogenic Signaling and Inducing Anti-tumor Immunity
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    Fecal miRNome and Proteome Profiling Uncovers Stage-Specific Biomarkers of Alzheimer’s Disease in 3×Tg-AD Mice
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    USP2 stabilizes POU2F3 and represents a therapeutic vulnerability in POU2F3-positive small cell lung cancer
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    A single Citrobacter rodentium infection in Pink1 knockout and wild-type mice leads to regional blood-brain-barrier perturbation and limited microglial activation without dopamine neuron axon terminal loss
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    Apatinib enhances anti-PD-1 efficacy by inhibiting Exo70-mediated exosome secretion in pMMR/MSS colorectal cancer
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    Keratinocytes and PDGF-B/PDGFRβ signaling modulate peripheral opioid tolerance
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  19. Jun 2026
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    Diet-Induced Amyloid Precursor Protein Dysregulation in Kidney and Adipose Tissue Mediates Mitochondrial Dysfunction
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    Mkrn3, Dlk1 and Mecp2 Have Distinct Hypothalamic Expression Patterns Across Pubertal Maturation in Male and Female Mice
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  22. May 2026
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    ALDH1A3 promotes the lung metastatic organotropism of pancreatic ductal adenocarcinoma through semaphorin signaling
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    Gut microbiota-derived succinate links proteostasis collapse to α-synuclein pathology and aging
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    JIN-A02, a Mutant-Selective Fourth-Generation EGFR inhibitor, Overcomes C797S-Mediated Resistance and Demonstrates Intracranial Activity in NSCLC
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  27. Apr 2026
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    Nuclear envelope budding enables export of large transcripts in muscle cells
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    SARM1 executes neuronal parthanatos and promotes excitotoxic cell death
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    A Rasa3-Gαi signaling axis orchestrates B lymphocyte trafficking into and through lymphoid organs
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  32. Mar 2026
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    Eicosapentaenoic acid reprograms cerebrovascular metabolism and impairs repair after brain injury, with relevance to chronic traumatic encephalopathy
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    NAD+ hydrolysis catalyzed by SelO is required for mitochondrial homeostasis
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  37. Feb 2026
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    Associations Between Klotho/FGF-Related Protein Expression in Peripheral Blood Mononuclear Cells, Inflammation, and Muscle Function in Middle-Aged Adults with Obesity: A Pilot Study
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    LRRC8A-containing anion channels promote glioblastoma proliferation via a WNK1/mTORC2-dependent mechanism
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  40. Jan 2026
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    Structure of the lysosomal KICSTOR-GATOR1-SAMTOR nutrient-sensing supercomplex
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  42. Dec 2025
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    Brain-Derived Neurotrophic Factor and Heat Shock Protein-32: Potential Targets for Microglial Response to Glucose and Oxygen Manipulation
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  44. Nov 2025
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    ZBP1-sensed hypoxic stress triggers intrinsic necroptosis in hepatocytes, aggravating hepatic ischemia-reperfusion injury: an experimental study
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  46. Oct 2025
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    Quercetin Increases Expression of Membrane-TRAIL in Glioblastoma Cells Resulting in Apoptosis
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  48. Sep 2025
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    Histone demethylase LSD1 regulates lipid homeostasis during Cryptococcus neoformans infection
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    An isoform-specific RUNX1C–BTG2 axis governs AML quiescence and chemoresistance.
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    Hypoxic stress dysregulates functions of glioma-associated myeloid cells through epigenomic and transcriptional programs
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  55. Aug 2025
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    Loss of NOTCH2 creates a TRIM28-dependent vulnerability in small cell lung cancer
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    Lysosomal TPC2 channel as a new target of chlorpromazine and Clomipramine to induce protective autophagy in L-BMAA-induced neurodegeneration
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  60. Jul 2025
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  62. Jun 2025
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  67. May 2025
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  71. Apr 2025
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    The carnosinase dipeptidase CNDP1 is a novel metabolic vulnerability in brain metastasis
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  75. Feb 2025
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    Female mice exhibit resistance to disease progression despite early pathology in a transgenic mouse model inoculated with alpha-synuclein fibrils
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    Dab1 expression level controls Reelin-induced PI3K-Akt activation in early GABAergic neurons
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  82. Jan 2025
  83. pubs.acs.org pubs.acs.org
    Tat-Beclin-1 Ameliorates Memory by Improving Neuronal Cytoarchitecture and Mitigating Mitochondrial Dysfunction in Scopolamine-Induced Amnesic Male Mice
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    Traumatic brain injury causes early aggregation of beta-amyloid peptides and NOTCH3 reduction in vascular smooth muscle cells of leptomeningeal arteries
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  89. Dec 2024
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    DEP-1 is a brain insulin receptor phosphatase that prevents the simultaneous activation of counteracting metabolic pathways
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  94. Nov 2024
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    PRDX6 dictates ferroptosis sensitivity by directing cellular selenium utilization
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  97. Oct 2024
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    Alzheimer’s disease-linked risk alleles elevate microglial cGAS-associated senescence and neurodegeneration in a tauopathy model
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  99. Sep 2024
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    Microbiota regulates neonatal disease tolerance to virus-evoked necrotizing enterocolitis by shaping the STAT1-NLRC5 axis in the intestinal epithelium
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  103. Aug 2024
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    TGM1/3-mediated transamidation of Exo70 promotes tumor metastasis upon LKB1 inactivation
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  215. Jun 2022
  216. www.sciencedirect.com www.sciencedirect.com
    IN BRAIN POST-ISCHEMIC PLASTICITY, Na+/Ca2+ EXCHANGER 1 AND Ascl1 INTERVENE IN MICROGLIA-DEPENDENT CONVERSION OF ASTROCYTES INTO NEURONAL LINEAGE
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  218. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Insights into the Mechanism of Human Deiodinase 1
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  219. May 2022
  220. aacrjournals.org aacrjournals.org
    Melanoma-secreted Amyloid Beta Suppresses Neuroinflammation and Promotes Brain Metastasis
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    aacrjournals.org/cancerdiscovery/article/12/5/1314/694563/Melanoma-Secreted-Amyloid-Beta-Suppresses
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    PAAN/MIF nuclease inhibition prevents neurodegeneration in Parkinson’s disease
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  222. Mar 2022
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    Hormone-sensitive lipase is localized at synapses and is necessary for normal memory functioning in mice
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    sciencedirect.com/science/article/pii/S0022227522000281
  224. elifesciences.org elifesciences.org
    Confined migration promotes cancer metastasis through resistance to anoikis and increased invasiveness
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  225. www.sciencedirect.com www.sciencedirect.com
    Local hyperthermia therapy induces browning of white fat and treats obesity
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  226. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Paradoxical neuronal hyperexcitability in a mouse model of mitochondrial pyruvate import deficiency
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  227. Feb 2022
  228. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Interleukin-6 triggers toxic neuronal iron sequestration in response to pathological α-synuclein
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  229. www.sciencedirect.com www.sciencedirect.com
    Zrsr2 and functional U12-dependent spliceosome are necessary for follicular development
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  230. Jan 2022
  231. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Genomic variants reducing expression of two endocytic receptors in 46,XY differences of sex development
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    onlinelibrary.wiley.com/doi/10.1002/humu.24325
  232. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Heat shock factor 1 (HSF1) cooperates with estrogen receptor α (ERα) in the regulation of estrogen action in breast cancer cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC8709578/
  233. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of Nuclear PTEN Tyrosine Phosphorylation Enhances Glioma Radiation Sensitivity through Attenuated DNA Repair
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    ncbi.nlm.nih.gov/pmc/articles/PMC8717880/
  234. Dec 2021
  235. www.sciencedirect.com www.sciencedirect.com
    Na+/Ca2+ exchanger isoform 1 (NCX1) and canonical transient receptor potential channel 6 (TRPC6) are recruited by STIM1 to mediate Store-Operated Calcium Entry in primary cortical neurons
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    RNA circles with minimized immunogenicity as potent PKR inhibitors
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  237. www.sciencedirect.com www.sciencedirect.com
    Circular RNA ZNF609/CKAP5 mRNA interaction regulates microtubule dynamics and tumorigenicity
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  238. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of extracellular vesicle-associated MMP2 abrogates intercellular hepatic miR-122 transfer to liver macrophages and curtails inflammation
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  239. Nov 2021
  240. academic.oup.com academic.oup.com
    Nobiletin-induced partial abrogation of deleterious effects of AKT inhibition on preimplantation bovine embryo development in vitro
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    APOL1 risk variants in individuals of African genetic ancestry drive endothelial cell defects that exacerbate sepsis
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  242. www.nature.com www.nature.com
    AKIRIN2 controls the nuclear import of proteasomes in vertebrates
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  243. elifesciences.org elifesciences.org
    A functional genetic toolbox for human tissue-derived organoids
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  244. Oct 2021
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    Aberrant RNA methylation triggers recruitment of an alkylation repair complex
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  246. www.nature.com www.nature.com
    Role of hippocampal NF-κB and GluN2B in the memory acquisition impairment of experiences gathered prior to cocaine administration in rats
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    TRIP12 ubiquitination of glucocerebrosidase contributes to neurodegeneration in Parkinson’s disease
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  248. www.sciencedirect.com www.sciencedirect.com
    Cholecystokinin 1 receptor activation restores normal mTORC1 signaling and is protective to Purkinje cells of SCA mice
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  249. Sep 2021
  250. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FKBP51 Affects TNF-Related Apoptosis Inducing Ligand Response in Melanoma
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