175 Matching Annotations
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  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PARG Governs a PARylation–Ubiquitination Toggle that Stabilizes RAD51AP1 to Drive Homologous Recombination–Mediated Chemoresistance
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    pmc.ncbi.nlm.nih.gov/articles/PMC13575561/
  3. Oct 2026
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    Host metadherin coordinates hepatic lipid metabolism and CD8+ T cell immunity to promote tumor progression
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    pmc.ncbi.nlm.nih.gov/articles/PMC13623212/
  5. Sep 2026
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    Dietary α-ketoglutarate modulates lung adenocarcinoma growth and epigenetic remodeling in a sex-dependent fashion
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    sciencedirect.com/science/article/pii/S2211124726011307
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    Establishment of a colorectal cancer liver metastasis (CRCLM) solitary tumor mouse model
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    Neutrophil elastase-mediated myoepithelial loss is a therapeutic vulnerability in ductal carcinoma in situ progression
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    Bacteroides acidifaciens enriched by KRAS mutation promotes colorectal tumorigenesis
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  10. Aug 2026
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    Host metadherin coordinates hepatic lipid metabolism and CD8+ T cell immunity to promote tumor progression
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    Genetically driven immune microenvironment states associate with therapeutic responses in MYD88 mutant lymphomas
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    Combined MYC Activation and PTEN Loss Drives Molecular Features of Aggressive Preinvasive Lesions in Mouse Prostate
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    Establishing the role of ZBTB20 mutations in GnRH deficiency and impaired neurogenesis in the subventricular zone: a human cohort and animal model study
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  15. Jul 2026
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    PD-1 blockade unleashes local hepatitis B virus-related B cell response inhibiting hepatocellular carcinoma
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    Targeted antibody-drug conjugates for rhabdomyosarcoma and other FGFR4-expressing cancers
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    Interaction and Reciprocal Stabilization of H3.3 and PARP1 Promotes DNA Damage Repair and Tumor Progression in Small Cell Lung Cancer
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  19. Jun 2026
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    Integrin CD11b/CD18 reprograms macrophage polarization by suppressing ERK/STAT3 signaling to enhance antitumor immunity in colitis-associated colorectal cancer
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    Dual modal pathomics model for colorectal cancer early recurrence prediction and mutation landscape analysis
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    Enhancing Immunotherapeutic Response in Colorectal Cancer with a Neuropilin-1-Targeting Tumor-Penetrating Peptide
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    Chaperone-mediated autophagy is a tumor-suppressive mechanism in hepatocellular carcinoma
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  24. May 2026
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    Mutant ribosomal protein RPS15 drives B cell malignancy through oxidative stress and genomic instability
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  26. Apr 2026
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    Anticancer activity of RAS-GTP inhibition in cholangiocarcinoma
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  29. Mar 2026
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    Optogenetic manipulation of estrogen receptor signaling to improve estrogen deficiency
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  31. Feb 2026
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    Sequential platinum and PARP Inhibition enhances PD1 immunotherapy efficacy in murine Brca2 mutated pancreatic cancer
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  33. Jan 2026
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    RAS/MEK/PI3K pathway inhibition augments response to CD40 agonism by targeting CD11b+ Bregs thereby overcoming melanoma PD1-resistance
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    A mouse model of busulfan-induced ovarian toxicity and evidence for attenuation with mTOR inhibition
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  36. Dec 2025
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    A K27-linked Ubiquitin Checkpoint Controls NOTCH Homeostasis
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  39. Oct 2025
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    TYK2 Promotes Immunosurveillance of Colorectal Cancer Liver Metastasis
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  41. Sep 2025
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  43. Aug 2025
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    Autophagy suppresses the formation of hepatocyte-derived cancer-initiating ductular progenitor cells in the liver
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    Tumor-resident probiotic Clostridium butyricum improves aPD-1 efficacy in colorectal cancer models by inhibiting IL-6-mediated immunosuppression
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    Intrahepatic Microbial Heterogeneity in Multifocal Hepatocellular Carcinoma and Its Association with Host Genomic and Transcriptomic Alterations
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  48. Jul 2025
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    ARID1A mutation drives gastric tumorigenesis via activating type 2 immune dominant microenvironment
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    RUNX2 inhibition disrupts a PAX3::FOXO1-RUNX2 feed-forward loop and dismantles oncogenic gene programs in fusion-positive rhabdomyosarcoma
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    The XPO1 inhibitor Eltanexor modulates the Wnt/β-catenin signaling pathway to reduce colorectal cancer tumorigenesis
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    Combined KRAS inhibition and immune therapy generates durable complete responses in an autochthonous PDAC model
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    Unlocking the therapeutic potential of rigosertib as a selective therapy for ovarian cancer
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  54. Jun 2025
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    Trametinib potentiates anti-PD-1 efficacy in tumors established from chemotherapy-primed pancreatic cancer cells
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  56. May 2025
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    Bacteroides fragilis promotes chemoresistance in colorectal cancer, and its elimination by phage VA7 restores chemosensitivity
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    KMT2C deficiency drives transdifferentiation of double-negative prostate cancer and confer resistance to AR-targeted therapy
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  59. Apr 2025
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    Circular RMST cooperates with lineage-driving transcription factors to govern neuroendocrine transdifferentiation
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  61. Mar 2025
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    Cross-kingdom-mediated detection of intestinal protozoa through NLRP6
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  63. Feb 2025
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    Protocol for 3D multiplexed fluorescent imaging of pulmonary TB lesions using Opal-TSA dyes for signal amplification
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  65. aacrjournals.org aacrjournals.org
    Scribble Deficiency Promotes Pancreatic Ductal Adenocarcinoma Development and Metastasis
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    SMAD4 and KRAS Status Shape Cancer Cell-Stromal Crosstalk and Therapeutic Response in Pancreatic Cancer
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    Combined inhibition of focal adhesion kinase and RAF/MEK elicits synergistic inhibition of melanoma growth and reduces metastases
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    Clioquinol inhibits angiogenesis by promoting VEGFR2 degradation and synergizes with AKT inhibition to suppress triple-negative breast cancer vascularization
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  69. Jan 2025
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    Endocrine-targeting therapies shift the breast microbiome to reduce estrogen receptor-α breast cancer risk
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  71. Dec 2024
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    Mechanism of enhancing chemotherapy efficacy in pancreatic ductal adenocarcinoma with paricalcitol and hydroxychloroquine
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    Human iPSC-derived myelinating organoids and globoid cells to study Krabbe disease
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  74. Nov 2024
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    Targeting BCL2 with Venetoclax Enhances the Efficacy of the KRASG12D Inhibitor MRTX1133 in Pancreatic Cancer
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  76. Sep 2024
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    Dietary vitamin B3 supplementation induces the antitumor immunity against liver cancer via biased GPR109A signaling in myeloid cell
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    Human iPSC-derived myelinating organoids and globoid cells to study Krabbe Disease
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  79. Aug 2024
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    The deubiquitinase USP9X regulates RIT1 protein abundance and oncogenic phenotypes
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    BCAA-producing Clostridium symbiosum promotes colorectal tumorigenesis through the modulation of host cholesterol metabolism
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  82. Jul 2024
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    Peptostreptococcus stomatis promotes colonic tumorigenesis and receptor tyrosine kinase inhibitor resistance by activating ERBB2-MAPK
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    Monoacylglycerol acyltransferase-2 inhibits colorectal carcinogenesis in APCmin+/− mice
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    Netrin signaling mediates survival of dormant epithelial ovarian cancer cells
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    Personalized drug screening using patient-derived organoid and its clinical relevance in gastric cancer
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    Mitochondrial perturbation in the intestine causes microbiota-dependent injury and gene signatures discriminative of inflammatory disease
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    Deubiquitylase OTUD3 regulates integrated stress response to suppress progression and sorafenib resistance of liver cancer
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  89. Apr 2024
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    Cancer immunotherapy via synergistic co-activation of myeloid receptors CD40 and Dectin-1
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    Telomere dysfunction alters intestinal stem cell dynamics to promote cancer
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    Intervention with metabolites emulating endogenous cell transitions accelerates muscle regeneration in young and aged mice
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  93. Mar 2024
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    ΔNp63 regulates MDSC survival and metabolism in triple-negative breast cancer
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    SIRT4 loss reprograms intestinal nucleotide metabolism to support proliferation following perturbation of homeostasis
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    Angiotensin II type-2 receptor signaling facilitates liver injury repair and regeneration via inactivation of Hippo pathway
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    ARID1A orchestrates SWI/SNF-mediated sequential binding of transcription factors with ARID1A loss driving pre-memory B cell fate and lymphomagenesis
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    Altered microbial bile acid metabolism exacerbates T cell-driven inflammation during graft-versus-host disease
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  99. Feb 2024
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    Roseburia intestinalis sensitizes colorectal cancer to radiotherapy through the butyrate/OR51E1/RALB axis
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    Streptococcus anginosus promotes gastric inflammation, atrophy, and tumorigenesis in mice
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  103. Dec 2023
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    Cancer immunotherapy via synergistic coactivation of myeloid receptors CD40 and Dectin-1
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  105. Nov 2023
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    ISX9 loaded thermoresponsive nanoparticles for hair follicle regrowth
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  107. Sep 2023
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    Influence of Vitamin D Deficiency on Cyclin D1-Induced Parathyroid Tumorigenesis
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    Coordination between ECM and cell-cell adhesion regulates the development of islet aggregation, architecture, and functional maturation
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    In vivo modeling of CLL transformation to Richter’s syndrome reveals convergent evolutionary paths and therapeutic vulnerabilities
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  111. Jul 2023
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    Interactions between host and intestinal crypt-resided biofilms are controlled by epithelial fucosylation
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  114. Jun 2023
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    Loss of Mettl3 enhances liver tumorigenesis by inducing hepatocyte dedifferentiation and hyperproliferation
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    Coupled deglycosylation-ubiquitination cascade in regulating PD-1 degradation by MDM2
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    Antiandrogen treatment induces stromal cell reprogramming to promote castration resistance in prostate cancer
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    Altered gut microbiota of obesity subjects promotes colorectal carcinogenesis in mice
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    Distinct Nrf2 Signaling Thresholds Mediate Lung Tumor Initiation and Progression
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    Macrophage PPARγ inhibits Gpr132 to mediate the anti-tumor effects of rosiglitazone
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    ncbi.nlm.nih.gov/pmc/articles/PMC5047746/