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23 Matching Annotations

Aug 2025
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SUCLG1 deficiency-induced histone succinylation impairs oncogene expression in acute myeloid leukemia

1
1. scibot 13 Aug 2025
  
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  RRID:AB_2620184
  
  DOI: 10.1016/j.celrep.2025.116147
  
  Resource: (Bethyl Cat# A301-985A100, RRID:AB_2620184)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S2211124725009180
Jul 2024
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Citrate metabolism controls the senescent microenvironment via the remodeling of pro-inflammatory enhancers

1
1. scibot 25 Jul 2024
  
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  RRID:AB_2620184
  
  DOI: 10.1016/j.celrep.2024.114496
  
  Resource: (Bethyl Cat# A301-985A100, RRID:AB_2620184)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S2211124724008258
Jan 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Bromodomain inhibitor i-BET858 triggers a unique transcriptional response coupled to enhanced DNA damage, cell cycle arrest and apoptosis in high-grade ovarian carcinoma cells

1
1. scibot 26 Jan 2024
  
  in Public
  
  AB_2620184
  
  DOI: 10.1186/s13148-023-01477-x
  
  Resource: (Bethyl Cat# A301-985A100, RRID:AB_2620184)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2620184
  
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  RRID:AB_2620184
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ncbi.nlm.nih.gov/pmc/articles/PMC10105475/
Nov 2022
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The epigenetic state of IL-4-polarized macrophages enables inflammatory cistromic expansion and extended synergistic response to TLR ligands

1
1. scibot 03 Nov 2022
  
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  AB_2620184
  
  DOI: 10.1016/j.immuni.2022.10.004
  
  Resource: (Bethyl Cat# A301-985A100, RRID:AB_2620184)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2620184
  
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sciencedirect.com/science/article/pii/S1074761322005453
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Acute depletion of human core nucleoporin reveals direct roles in transcription control but dispensability for 3D genome organization

1
1. scibot 03 Nov 2022
  
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  RRID:AB_2620184
  
  DOI: 10.1016/j.celrep.2022.111576
  
  Resource: (Bethyl Cat# A301-985A100, RRID:AB_2620184)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S2211124722014371
Jun 2022
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YAP1 maintains active chromatin state in head and neck squamous cell carcinomas that promotes tumorigenesis through cooperation with BRD4

1
1. scibot 15 Jun 2022
  
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  RRID:AB_2620184
  
  DOI: 10.1016/j.celrep.2022.110970
  
  Resource: (Bethyl Cat# A301-985A100, RRID:AB_2620184)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2620184
  
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sciencedirect.com/science/article/pii/S2211124722007562
Aug 2021
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Enhancer RNA m6A methylation facilitates transcriptional condensate formation and gene activation

1
1. scibot 15 Aug 2021
  
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  RRID:AB_2620184
  
  DOI: 10.1016/j.molcel.2021.07.024
  
  Resource: (Bethyl Cat# A301-985A100, RRID:AB_2620184)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2620184
  
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sciencedirect.com/science/article/pii/S1097276521005931
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ZMYND8-regulated IRF8 transcription axis is an acute myeloid leukemia dependency

1
1. scibot 06 Aug 2021
  
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  RRID:AB_2620184
  
  DOI: 10.1016/j.molcel.2021.07.018
  
  Resource: (Bethyl Cat# A301-985A100, RRID:AB_2620184)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2620184
  
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sciencedirect.com/science/article/pii/S1097276521005876
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Resistance to Epigenetic-Targeted Therapy Engenders Tumor Cell Vulnerabilities Associated with Enhancer Remodeling

1
1. scibot 05 Aug 2021
  
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  AB_2620184
  
  DOI: 10.1016/j.ccell.2018.11.005
  
  Resource: (Bethyl Cat# A301-985A100, RRID:AB_2620184)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2620184
  
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sciencedirect.com/science/article/pii/S1535610818305269
Jul 2021
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Metabolically controlled histone H4K5 acylation/acetylation ratio drives BRD4 genomic distribution

1
1. scibot 30 Jul 2021
  
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  RRID:AB_2620184
  
  DOI: 10.1016/j.celrep.2021.109460
  
  Resource: (Bethyl Cat# A301-985A100, RRID:AB_2620184)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2620184
  
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sciencedirect.com/science/article/pii/S2211124721008834
Jun 2021
www.nature.com www.nature.com

Pericentromeric Satellite III transcripts induce etoposide resistance

1
1. scibot 02 Jun 2021
  
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  RRID:AB_2620184
  
  DOI: 10.1038/s41419-021-03810-9
  
  Resource: (Bethyl Cat# A301-985A100, RRID:AB_2620184)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2620184
  
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  RRID:AB_2620184
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nature.com/articles/s41419-021-03810-9
May 2021
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Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition

1
1. scibot 21 May 2021
  
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  RRID:AB_2620184
  
  DOI: 10.1016/j.molcel.2021.04.015
  
  Resource: (Bethyl Cat# A301-985A100, RRID:AB_2620184)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2620184
  
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sciencedirect.com/science/article/pii/S1097276521003208
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Enhancers are activated by p300/CBP activity-dependent PIC assembly, RNAPII recruitment, and pause release

1
1. scibot 08 May 2021
  
  in Public
  
  RRID:AB_2620184
  
  DOI: 10.1016/j.molcel.2021.03.008
  
  Resource: (Bethyl Cat# A301-985A100, RRID:AB_2620184)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2620184
  
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sciencedirect.com/science/article/pii/S1097276521001763
Apr 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Evidence for additive and synergistic action of mammalian enhancers during cell fate determination

1
1. scibot 02 Apr 2021
  
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  RRID:AB_2620184
  
  DOI: 10.7554/eLife.65381
  
  Resource: (Bethyl Cat# A301-985A100, RRID:AB_2620184)
  
  Curator: @evieth
  
  SciCrunch record: RRID:AB_2620184
  
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  RRID:AB_2620184 RRIDCUR:Validated
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ncbi.nlm.nih.gov/pmc/articles/PMC8004103/
Jan 2021
www.sciencedirect.com www.sciencedirect.com

HDAC inhibition results in widespread alteration of the histone acetylation landscape and BRD4 targeting to gene bodies

1
1. scibot 20 Jan 2021
  
  in Public
  
  RRID:AB_2620184
  
  DOI: 10.1016/j.celrep.2020.108638
  
  Resource: (Bethyl Cat# A301-985A100, RRID:AB_2620184)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2620184
  
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  RRIDCUR:Validated RRID:AB_2620184
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sciencedirect.com/science/article/pii/S2211124720316272
Sep 2020
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Dysregulation of BRD4 Function Underlies the Functional Abnormalities of MeCP2 Mutant Neurons

1
1. scibot 23 Sep 2020
  
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  RRID:AB_2620184
  
  DOI: 10.1016/j.molcel.2020.05.016
  
  Resource: (Bethyl Cat# A301-985A100, RRID:AB_2620184)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2620184
  
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  RRID:AB_2620184 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1097276520303178
elifesciences.org elifesciences.org

NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency

1
1. scibot 17 Sep 2020
  
  in Public
  
  RRID:AB_2620184
  
  DOI: 10.7554/eLife.54993
  
  Resource: (Bethyl Cat# A301-985A100, RRID:AB_2620184)
  
  Curator: @evieth
  
  SciCrunch record: RRID:AB_2620184
  
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  RRID:AB_2620184 RRIDCUR:Validated
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elifesciences.org/articles/54993
Jan 2020
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The Leukemogenic TCF3-HLF Complex Rewires Enhancers Driving Cellular Identity and Self-Renewal Conferring EP300 Vulnerability

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:AB_2620184
  
  DOI: 10.1016/j.ccell.2019.10.004
  
  Resource: (Bethyl Cat# A301-985A100, RRID:AB_2620184)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2620184
  
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  RRID:AB_2620184 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1535610819304787
www.sciencedirect.com www.sciencedirect.com

Plasticity of the Cullin-RING Ligase Repertoire Shapes Sensitivity to Ligand-Induced Protein Degradation

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:AB_2620184
  
  DOI: 10.1016/j.molcel.2019.07.013
  
  Resource: (Bethyl Cat# A301-985A100, RRID:AB_2620184)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2620184
  
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  RRID:AB_2620184 RRIDCUR:Validated
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scibot

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sciencedirect.com/science/article/pii/S109727651930543X
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Superior efficacy of cotreatment with BET protein inhibitor and BCL2 or MCL1 inhibitor against AML blast progenitor cells

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:AB_2620184
  
  DOI: 10.1038/s41408-018-0165-5
  
  Resource: (Bethyl Cat# A301-985A100, RRID:AB_2620184)
  
  Curator: @evieth
  
  SciCrunch record: RRID:AB_2620184
  
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  RRID:AB_2620184 RRIDCUR:Validated
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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC6333829/
Nov 2018
www.sciencedirect.com www.sciencedirect.com

ZFX Mediates Non-canonical Oncogenic Functions of the Androgen Receptor Splice Variant 7 in Castrate-Resistant Prostate Cancer

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:AB_2620184
  
  Curator: @Jmenke
  
  Resource used:
  
  (Bethyl Cat# A301-985A100, RRID:AB_2620184)
  
  SciCrunch record: RRID:AB_2620184
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
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  RRID:AB_2620184 RRIDCUR:Validated
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RRID:AB_2620184

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sciencedirect.com/science/article/pii/S1097276518306890
www.sciencedirect.com www.sciencedirect.com

Identification of Therapeutic Targets in Rhabdomyosarcoma through Integrated Genomic, Epigenomic, and Proteomic Analyses

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:AB_2620184
  
  Resource used:
  
  (Bethyl Cat# A301-985A100, RRID:AB_2620184)
  
  SciCrunch record: RRID:AB_2620184
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
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  RRID:AB_2620184
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sciencedirect.com/science/article/pii/S1535610818303180
Nov 2017
www.sciencedirect.com www.sciencedirect.com

Transcriptional Dependencies in Diffuse Intrinsic Pontine Glioma

1
1. scibot 08 Nov 2017
  
  in Public
  
  AB_2620184
  
  Curator: @gabimpine
  
  Resource used:
  
  (Bethyl Cat# A301-985A100, RRID:AB_2620184)
  
  SciCrunch record: RRID:AB_2620184
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
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  RRID:AB_2620184 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:AB_2620184

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scibot

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sciencedirect.com/science/article/pii/S1535610817301071