22 Matching Annotations
  1. Last 7 days
  2. www.sciencedirect.com www.sciencedirect.com
    Citrate metabolism controls the senescent microenvironment via the remodeling of pro-inflammatory enhancers
    1
    1. scibot 25 Jul 2024
      RRID:AB_2620184

      DOI: 10.1016/j.celrep.2024.114496

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    sciencedirect.com/science/article/pii/S2211124724008258
  3. Jan 2024
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bromodomain inhibitor i-BET858 triggers a unique transcriptional response coupled to enhanced DNA damage, cell cycle arrest and apoptosis in high-grade ovarian carcinoma cells
    1
    1. scibot 26 Jan 2024
      AB_2620184

      DOI: 10.1186/s13148-023-01477-x

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    ncbi.nlm.nih.gov/pmc/articles/PMC10105475/
  5. Nov 2022
  6. www.sciencedirect.com www.sciencedirect.com
    The epigenetic state of IL-4-polarized macrophages enables inflammatory cistromic expansion and extended synergistic response to TLR ligands
    1
    1. scibot 03 Nov 2022
      AB_2620184

      DOI: 10.1016/j.immuni.2022.10.004

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    sciencedirect.com/science/article/pii/S1074761322005453
  7. www.sciencedirect.com www.sciencedirect.com
    Acute depletion of human core nucleoporin reveals direct roles in transcription control but dispensability for 3D genome organization
    1
    1. scibot 03 Nov 2022
      RRID:AB_2620184

      DOI: 10.1016/j.celrep.2022.111576

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    sciencedirect.com/science/article/pii/S2211124722014371
  8. Jun 2022
  9. www.sciencedirect.com www.sciencedirect.com
    YAP1 maintains active chromatin state in head and neck squamous cell carcinomas that promotes tumorigenesis through cooperation with BRD4
    1
    1. scibot 15 Jun 2022
      RRID:AB_2620184

      DOI: 10.1016/j.celrep.2022.110970

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    sciencedirect.com/science/article/pii/S2211124722007562
  10. Aug 2021
  11. www.sciencedirect.com www.sciencedirect.com
    Enhancer RNA m6A methylation facilitates transcriptional condensate formation and gene activation
    1
    1. scibot 15 Aug 2021
      RRID:AB_2620184

      DOI: 10.1016/j.molcel.2021.07.024

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    sciencedirect.com/science/article/pii/S1097276521005931
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    ZMYND8-regulated IRF8 transcription axis is an acute myeloid leukemia dependency
    1
    1. scibot 06 Aug 2021
      RRID:AB_2620184

      DOI: 10.1016/j.molcel.2021.07.018

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    sciencedirect.com/science/article/pii/S1097276521005876
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    Resistance to Epigenetic-Targeted Therapy Engenders Tumor Cell Vulnerabilities Associated with Enhancer Remodeling
    1
    1. scibot 05 Aug 2021
      AB_2620184

      DOI: 10.1016/j.ccell.2018.11.005

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    sciencedirect.com/science/article/pii/S1535610818305269
  14. Jul 2021
  15. www.sciencedirect.com www.sciencedirect.com
    Metabolically controlled histone H4K5 acylation/acetylation ratio drives BRD4 genomic distribution
    1
    1. scibot 30 Jul 2021
      RRID:AB_2620184

      DOI: 10.1016/j.celrep.2021.109460

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    sciencedirect.com/science/article/pii/S2211124721008834
  16. Jun 2021
  17. www.nature.com www.nature.com
    Pericentromeric Satellite III transcripts induce etoposide resistance
    1
    1. scibot 02 Jun 2021
      RRID:AB_2620184

      DOI: 10.1038/s41419-021-03810-9

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    nature.com/articles/s41419-021-03810-9
  18. May 2021
  19. www.sciencedirect.com www.sciencedirect.com
    Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition
    1
    1. scibot 21 May 2021
      RRID:AB_2620184

      DOI: 10.1016/j.molcel.2021.04.015

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    sciencedirect.com/science/article/pii/S1097276521003208
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    Enhancers are activated by p300/CBP activity-dependent PIC assembly, RNAPII recruitment, and pause release
    1
    1. scibot 08 May 2021
      RRID:AB_2620184

      DOI: 10.1016/j.molcel.2021.03.008

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    sciencedirect.com/science/article/pii/S1097276521001763
  21. Apr 2021
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Evidence for additive and synergistic action of mammalian enhancers during cell fate determination
    1
    1. scibot 02 Apr 2021
      RRID:AB_2620184

      DOI: 10.7554/eLife.65381

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      Curator: @evieth

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    ncbi.nlm.nih.gov/pmc/articles/PMC8004103/
  23. Jan 2021
  24. www.sciencedirect.com www.sciencedirect.com
    HDAC inhibition results in widespread alteration of the histone acetylation landscape and BRD4 targeting to gene bodies
    1
    1. scibot 20 Jan 2021
      RRID:AB_2620184

      DOI: 10.1016/j.celrep.2020.108638

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      Curator: @Naa003

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    sciencedirect.com/science/article/pii/S2211124720316272
  25. Sep 2020
  26. www.sciencedirect.com www.sciencedirect.com
    Dysregulation of BRD4 Function Underlies the Functional Abnormalities of MeCP2 Mutant Neurons
    1
    1. scibot 23 Sep 2020
      RRID:AB_2620184

      DOI: 10.1016/j.molcel.2020.05.016

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    sciencedirect.com/science/article/pii/S1097276520303178
  27. elifesciences.org elifesciences.org
    NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency
    1
    1. scibot 17 Sep 2020
      RRID:AB_2620184

      DOI: 10.7554/eLife.54993

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    elifesciences.org/articles/54993
  28. Jan 2020
  29. www.sciencedirect.com www.sciencedirect.com
    The Leukemogenic TCF3-HLF Complex Rewires Enhancers Driving Cellular Identity and Self-Renewal Conferring EP300 Vulnerability
    1
    1. scibot 13 Jan 2020
      RRID:AB_2620184

      DOI: 10.1016/j.ccell.2019.10.004

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      Curator: @ethanbadger

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    sciencedirect.com/science/article/pii/S1535610819304787
  30. www.sciencedirect.com www.sciencedirect.com
    Plasticity of the Cullin-RING Ligase Repertoire Shapes Sensitivity to Ligand-Induced Protein Degradation
    1
    1. scibot 13 Jan 2020
      RRID:AB_2620184

      DOI: 10.1016/j.molcel.2019.07.013

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      Curator: @ethanbadger

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    sciencedirect.com/science/article/pii/S109727651930543X
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Superior efficacy of cotreatment with BET protein inhibitor and BCL2 or MCL1 inhibitor against AML blast progenitor cells
    1
    1. scibot 13 Jan 2020
      RRID:AB_2620184

      DOI: 10.1038/s41408-018-0165-5

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      Curator: @evieth

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    ncbi.nlm.nih.gov/pmc/articles/PMC6333829/
  32. Nov 2018
  33. www.sciencedirect.com www.sciencedirect.com
    ZFX Mediates Non-canonical Oncogenic Functions of the Androgen Receptor Splice Variant 7 in Castrate-Resistant Prostate Cancer
    1
    1. scibot 05 Nov 2018
      RRID:AB_2620184

      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S1097276518306890
  34. www.sciencedirect.com www.sciencedirect.com
    Identification of Therapeutic Targets in Rhabdomyosarcoma through Integrated Genomic, Epigenomic, and Proteomic Analyses
    1
    1. scibot 05 Nov 2018
      RRID:AB_2620184

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    sciencedirect.com/science/article/pii/S1535610818303180
  35. Nov 2017
  36. www.sciencedirect.com www.sciencedirect.com
    Transcriptional Dependencies in Diffuse Intrinsic Pontine Glioma
    1
    1. scibot 08 Nov 2017
      AB_2620184

      Curator: @gabimpine

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    sciencedirect.com/science/article/pii/S1535610817301071