171 Matching Annotations
  1. Last 7 days
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    ISGylation by HERCs facilitates STING activation
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    sciencedirect.com/science/article/pii/S2211124724004637
  3. Apr 2024
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    H2AK119ub1 differentially fine-tunes gene expression by modulating canonical PRC1- and H1-dependent chromatin compaction
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    sciencedirect.com/science/article/pii/S1097276524001369
  5. Mar 2024
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    Inter-organ steroid hormone signaling promotes myoblast fusion via direct transcriptional regulation of a single key effector gene
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    Rim aperture of yeast autophagic membranes balances cargo inclusion with vesicle maturation
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    Jasmonate signaling pathway confers salt tolerance through a NUCLEAR FACTOR-Y trimeric transcription factor complex in Arabidopsis
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    sciencedirect.com/science/article/pii/S2211124724001530
  9. Feb 2024
  10. 52.53.155.43 52.53.155.43
    AURKA enhances the glycolysis and development of ovarian endometriosis through ERβ
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    RHOAL57V drives the development of diffuse gastric cancer through IGF1R-PAK1-YAP1 signaling
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    Human YKT6 forms priming complex with STX17 and SNAP29 to facilitate autophagosome-lysosome fusion
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    sciencedirect.com/science/article/pii/S2211124724000883
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    p53 promotes antiviral innate immunity by driving hexosamine metabolism
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  14. Jan 2024
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    RHOAL57V drives the development of diffuse gastric cancer through IGF1R-PAK1-YAP1 signaling
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    1. scibot 20 Jan 2024
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  16. Dec 2023
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ADAMTS-4 enhances oligodendrocyte differentiation and remyelination by cleaving NG2 proteoglycan and attenuating PDGFRα signaling
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    ncbi.nlm.nih.gov/pmc/articles/PMC10278682/
  18. Nov 2023
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    Single-molecule quantitation of RNA-binding protein occupancy and stoichiometry defines a role for Yra1 (Aly/REF) in nuclear mRNP organization
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    sciencedirect.com/science/article/pii/S2211124723014274
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    PTIR1 acts as an isoform of DDX58 and promotes tumor immune resistance through activation of UCHL5
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  21. 52.53.155.43 52.53.155.43
    mvad090-html.html
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  22. Sep 2023
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identifying G protein-coupled receptors involved in adipose tissue function using the innovative RNA-seq database FATTLAS
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    ncbi.nlm.nih.gov/pmc/articles/PMC10520334/
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    LAT1 (SLC7A5) catalyzes Copper(histidinate) transport switching from antiport to uniport mechanism.
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    sciencedirect.com/science/article/pii/S2589004223018151
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    CCDC50 promotes tumor growth through regulation of lysosome homeostasis
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  26. Aug 2023
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    PIIS2211124723009774-html.html
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  28. Jul 2023
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    Phosphoribosyl-linked serine ubiquitination of USP14 by the SidE family effectors of Legionella excludes p62 from the bacterial phagosome
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    sciencedirect.com/science/article/pii/S2211124723008288
  30. Jun 2023
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    4405.full-html.html
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  32. May 2023
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    Comparative Analysis of Six IRF Family Members in Alveolar Epithelial Cell-Intrinsic Antiviral Responses
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    mdpi.com/2073-4409/10/10/2600/htm
  34. Apr 2023
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    UBQLN2 restrains the domesticated retrotransposon PEG10 to maintain neuronal health in ALS
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    ncbi.nlm.nih.gov/pmc/articles/PMC10076021/
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    γ-Protocadherins control synapse formation and peripheral branching of touch sensory neurons
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      DOI: 10.1016/j.neuron.2023.03.012

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    Z-REX: shepherding reactive electrophiles to specific proteins expressed tissue specifically or ubiquitously, and recording the resultant functional electrophile-induced redox responses in larval fish
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      DOI: 10.1038/s41596-023-00809-8

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    Newly synthesized AIFM1 determines the hypersensitivity of T lymphocytes to STING activation-induced cell apoptosis
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    sciencedirect.com/science/article/pii/S2211124723003388
  39. Mar 2023
  40. www.sciencedirect.com www.sciencedirect.com
    A central chaperone-like role for 14-3-3 proteins in human cells
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    sciencedirect.com/science/article/pii/S1097276523001211
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    Targeting androgen receptor and the variants by an orally bioavailable Proteolysis Targeting Chimeras compound in castration resistant prostate cancer
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    sciencedirect.com/science/article/pii/S2352396423000658
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    COP I and II dependent trafficking controls ER-associated degradation in mammalian cells
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    sciencedirect.com/science/article/pii/S2589004223003097
  43. Feb 2023
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ARMS-NF-κB signaling regulates intracellular ROS to induce autophagy-associated cell death upon oxidative stress
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    ncbi.nlm.nih.gov/pmc/articles/PMC9926119/
  45. Jan 2023
  46. www.biorxiv.org www.biorxiv.org
    Multimodal HLA-I genotype regulation by human cytomegalovirus US10 and resulting surface patterning
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      DOI: 10.1101/2023.01.10.523457

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    biorxiv.org/content/10.1101/2023.01.10.523457v1
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    GSNOR deficiency promotes tumor growth via FAK1 S-nitrosylation
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    sciencedirect.com/science/article/pii/S2211124723000086
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    CYLD deubiquitinates plakoglobin to promote Cx43 membrane targeting and gap junction assembly in the heart
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      DOI: 10.1016/j.celrep.2022.111864

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    sciencedirect.com/science/article/pii/S2211124722017600
  49. Dec 2022
  50. elifesciences.org elifesciences.org
    Z-REX uncovers a bifurcation in function of Keap1 paralogs
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      DOI: 10.7554/eLife.83373

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    elifesciences.org/articles/83373
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    GwAAP: A genome-wide amino acid coding-decoding quantitative proteomics system
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      DOI: 10.1016/j.isci.2022.105471

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    ncbi.nlm.nih.gov/pmc/articles/PMC9713327/
  52. Nov 2022
  53. www.sciencedirect.com www.sciencedirect.com
    Branched-chain amino acid catabolism breaks glutamine addiction to sustain hepatocellular carcinoma progression
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    sciencedirect.com/science/article/pii/S2211124722015650
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    MsrB1-regulated GAPDH oxidation plays programmatic roles in shaping metabolic and inflammatory signatures during macrophage activation
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    sciencedirect.com/science/article/pii/S2211124722014632
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    CROCCP2 acts as a human-specific modifier of cilia dynamics and mTOR signaling to promote expansion of cortical progenitors
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  56. Oct 2022
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  58. Sep 2022
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    Synthetic refactor of essential genes decodes functionally constrained sequences in yeast genome
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    Closely related type II-C Cas9 orthologs recognize diverse PAMs
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  61. Aug 2022
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    RBM45 is an m6A-binding protein that affects neuronal differentiation and the splicing of a subset of mRNAs
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    Krüppel-like factor 5 rewires NANOG regulatory network to activate human naive pluripotency specific LTR7Ys and promote naive pluripotency
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    The transcription factor E2F1 controls the GLP-1 receptor pathway in pancreatic β cells
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    Neprilysins regulate muscle contraction and heart function via cleavage of SERCA-inhibitory micropeptides
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  67. Jul 2022
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    FAM69C, a kinase critical for synaptic function and memory, is defective in neurodegenerative dementia
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    UBP12 and UBP13 deubiquitinases destabilize the CRY2 blue light receptor to regulate Arabidopsis growth
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    Deubiquitinase OTUD3 regulates metabolism homeostasis in response to nutritional stresses
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  72. Mar 2022
  73. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    PTENα regulates endocytosis and modulates olfactory function
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  74. Feb 2022
  75. bmcbiol.biomedcentral.com bmcbiol.biomedcentral.com
    Competition between type I activin and BMP receptors for binding to ACVR2A regulates signaling to distinct Smad pathways
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  76. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
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    Mitochondrial retrograde signaling through UCP1-mediated inhibition of the plant oxygen-sensing pathway
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    ROPGAP-dependent interaction between brassinosteroid and ROP2-GTPase signaling controls pavement cell shape in Arabidopsis
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  79. Jan 2022
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    GS-CA1 and lenacapavir stabilize the HIV-1 core and modulate the core interaction with cellular factors
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  81. Dec 2021
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    Protein modifications throughout the lung cancer proteome unravel the cancer-specific regulation of glycolysis
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    Phosphorylation at Ser68 facilitates DCAF11-mediated ubiquitination and degradation of CENP-A during the cell cycle
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  86. Oct 2021
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    RNF8-mediated regulation of Akt promotes lung cancer cell survival and resistance to DNA damage
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  88. Sep 2021
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    Not4 and Not5 modulate translation elongation by Rps7A ubiquitination, Rli1 moonlighting, and condensates that exclude eIF5A
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  90. Aug 2021
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    Androgen signaling connects short isoform production to breakpoint formation at Ewing sarcoma breakpoint region 1
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    Chemogenomics identifies acetyl-coenzyme A synthetase as a target for malaria treatment and prevention
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    Secretion of Tau via an Unconventional Non-vesicular Mechanism
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    PTENα regulates endocytosis and modulates olfactory function
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    Transmembrane Protease TMPRSS11B Promotes Lung Cancer Growth by Enhancing Lactate Export and Glycolytic Metabolism
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    Boosting ATM activity alleviates aging and extends lifespan in a mouse model of progeria
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  102. Jul 2021
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    Negative Regulator of Ubiquitin-Like Protein 1 modulates the autophagy-lysosomal pathway via p62 to facilitate the extracellular release of tau following proteasome impairment
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      mouse monoclonal anti-HA

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    FipoQ/FBXO33, a Cullin‐1‐based ubiquitin ligase complex component modulates ubiquitination and solubility of polyglutamine disease protein
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    Secretion of Tau via an Unconventional Non-vesicular Mechanism
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    Ribosome ADP-ribosylation inhibits translation and maintains proteostasis in cancers
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    The mitochondrial protein ERAL1 suppresses RNA virus infection by facilitating RIG-I-like receptor signaling
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  131. Nov 2020
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    Type-IInterferon-Inducible SERTAD3 Inhibits Influenza A Virus Replication by Blocking the Assembly of Viral RNA Polymerase Complex
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    TGF-β-Induced Phosphorylation of Usp9X Stabilizes Ankyrin-G and Regulates Dendritic Spine Development and Maintenance
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    Inhibition of Resistance-Refractory P. falciparum Kinase PKG Delivers Prophylactic, Blood Stage, and Transmission-Blocking Antiplasmodial Activity
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    Cyclophilin A Prevents HIV-1 Restriction in Lymphocytes by Blocking Human TRIM5α Binding to the Viral Core
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    ASK1-Mediated Phosphorylation Blocks HDAC6 Ubiquitination and Degradation to Drive the Disassembly of Photoreceptor Connecting Cilia
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    The Human Cytomegalovirus pUL145 Isoforms Act as Viral DDB1-Cullin-Associated Factors to Instruct Host Protein Degradation to Impede Innate Immunity
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    Non-coding RNA Transcription in Tetrahymena Meiotic Nuclei Requires Dedicated Mediator Complex-Associated Proteins
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    Disease-Causing Mutations in SF3B1 Alter Splicing by Disrupting Interaction with SUGP1
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    Arc Oligomerization Is Regulated by CaMKII Phosphorylation of the GAG Domain: An Essential Mechanism for Plasticity and Memory Formation
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    Reciprocal Effects of Fibroblast Growth Factor Receptor Signaling on Dengue Virus Replication and Virion Production
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    Analysis of Drosophila STING Reveals an Evolutionarily Conserved Antimicrobial Function
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    A Potent and Specific CD38 Inhibitor Ameliorates Age-Related Metabolic Dysfunction by Reversing Tissue NAD+ Decline
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    Prp19/Pso4 Is an Autoinhibited Ubiquitin Ligase Activated by Stepwise Assembly of Three Splicing Factors
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    Injury Activates Ca2+/Calmodulin-Dependent Phosphorylation of JAV1-JAZ8-WRKY51 Complex for Jasmonate Biosynthesis
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    MPK3- and MPK6-Mediated ICE1 Phosphorylation Negatively Regulates ICE1 Stability and Freezing Tolerance in Arabidopsis
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    sciencedirect.com/science/article/pii/S1534580717307840
  198. www.sciencedirect.com www.sciencedirect.com
    Electron Cryo-microscopy Structure of Ebola Virus Nucleoprotein Reveals a Mechanism for Nucleocapsid-like Assembly
    1
    1. scibot 05 Nov 2018
      AB_262051

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    sciencedirect.com/science/article/pii/S0092867418301533
  199. www.sciencedirect.com www.sciencedirect.com
    OsMAPK3 Phosphorylates OsbHLH002/OsICE1 and Inhibits Its Ubiquitination to Activate OsTPP1 and Enhances Rice Chilling Tolerance
    1
    1. scibot 05 Nov 2018
      RRID:AB_262051

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      (Sigma-Aldrich Cat# H3663, RRID:AB_262051)

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      RRID:AB_262051
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    sciencedirect.com/science/article/pii/S1534580717309516
  200. europepmc.org europepmc.org
    Epidermal Growth Factor Receptor neddylation is regulated by a desmosomal-COP9 (Constitutive Photomorphogenesis 9) signalosome complex.
    1
    1. scibot 05 Nov 2018
      RRID:AB_262051

      Curator: @evieth

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      (Sigma-Aldrich Cat# H3663, RRID:AB_262051)

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      RRID:AB_262051
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    europepmc.org/articles/PMC5663478/
  201. Nov 2017
  202. www.sciencedirect.com www.sciencedirect.com
    The Plasticity of the Hsp90 Co-chaperone System
    1
    1. scibot 08 Nov 2017
      RRID:AB_262051

      Curator: @Jmenke

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      (Sigma-Aldrich Cat# H3663, RRID:AB_262051)

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      RRID:AB_262051 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1097276517305786
  203. www.sciencedirect.com www.sciencedirect.com
    Retrograde Synaptic Inhibition Is Mediated by α-Neurexin Binding to the α2δ Subunits of N-Type Calcium Channels
    1
    1. scibot 08 Nov 2017
      AB_262051

      Curator: @chewbeccax

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      (Sigma-Aldrich Cat# H3663, RRID:AB_262051)

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      RRID:AB_262051 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S0896627317305160
  204. www.sciencedirect.com www.sciencedirect.com
    Plasma Membrane CRPK1-Mediated Phosphorylation of 14-3-3 Proteins Induces Their Nuclear Import to Fine-Tune CBF Signaling during Cold Response
    1
    1. scibot 08 Nov 2017
      Cat#H3663

      Curator: @Zeljana_Babic

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      (Sigma-Aldrich Cat# H3663, RRID:AB_262051)

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      RRID:AB_262051 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S1097276517301314
  205. www.sciencedirect.com www.sciencedirect.com
    Gene Resistance to Transcriptional Reprogramming following Nuclear Transfer Is Directly Mediated by Multiple Chromatin-Repressive Pathways
    1
    1. scibot 08 Nov 2017
      AB_262051

      Curator: @Zeljana_Babic

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      (Sigma-Aldrich Cat# H3663, RRID:AB_262051)

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      RRID:AB_262051 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1097276517300564
  206. www.sciencedirect.com www.sciencedirect.com
    NBS1 Phosphorylation Status Dictates Repair Choice of Dysfunctional Telomeres
    1
    1. scibot 08 Nov 2017
      AB_262051

      Curator: @Zeljana_Babic

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      (Sigma-Aldrich Cat# H3663, RRID:AB_262051)

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      RRID:AB_262051 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1097276517300424
  207. www.sciencedirect.com www.sciencedirect.com
    Phosphorylation-Dependent Feedback Inhibition of RIG-I by DAPK1 Identified by Kinome-wide siRNA Screening
    1
    1. scibot 08 Nov 2017
      AB_262051

      Curator: @Zeljana_Babic

      Resource used:

      (Sigma-Aldrich Cat# H3663, RRID:AB_262051)

      SciCrunch record: RRID:AB_262051

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      RRID:AB_262051 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1097276516308644
  208. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Drosophila neprilysins control insulin signaling and food intake via cleavage of regulatory peptides
    1
    1. scibot 08 Nov 2017
      AB_262051

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      (Sigma-Aldrich Cat# H3663, RRID:AB_262051)

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      RRID:AB_262051
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    ncbi.nlm.nih.gov/pmc/articles/PMC5140268/