229 Matching Annotations
  1. Nov 2024
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    GM1 Oligosaccharide Ameliorates Rett Syndrome Phenotypes In Vitro and In Vivo via Trk Receptor Activation
    1
    1. scibot 14 Nov 2024
      RRID:AB_2629281

      DOI: 10.3390/ijms252111555

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    pmc.ncbi.nlm.nih.gov/articles/PMC11547101/
  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Detecting altered hepatic lipid oxidation by MRI in an animal model of MASLD
    1
    1. scibot 07 Nov 2024
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      DOI: 10.1016/j.xcrm.2024.101714

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    pmc.ncbi.nlm.nih.gov/articles/PMC11525016/
  4. elifesciences.org elifesciences.org
    Integrative study of skeletal muscle mitochondrial dysfunction in a murine pancreatic cancer-induced cachexia model
    1
    1. scibot 07 Nov 2024
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      DOI: 10.7554/eLife.93312

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    elifesciences.org/articles/93312
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Laminin-α2 chain deficiency in skeletal muscle causes dysregulation of multiple cellular mechanisms
    1
    1. scibot 07 Nov 2024
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      DOI: 10.26508/lsa.202402829

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    ncbi.nlm.nih.gov/pmc/articles/PMC11463332/
  6. Oct 2024
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitochondria remodeling during endometrial stromal cell decidualization
    1
    1. scibot 08 Oct 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC11452479/
  8. www.nature.com www.nature.com
    QSOX2 Deficiency-induced short stature, gastrointestinal dysmotility and immune dysfunction
    1
    1. scibot 01 Oct 2024
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      DOI: 10.1038/s41467-024-52587-w

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    nature.com/articles/s41467-024-52587-w
  9. Sep 2024
  10. www.sciencedirect.com www.sciencedirect.com
    Diabesity alters the protective effects of estrogens on endothelial function through adipose tissue secretome
    1
    1. scibot 10 Sep 2024
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      DOI: 10.1016/j.freeradbiomed.2024.09.001

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    sciencedirect.com/science/article/pii/S0891584924006397
  11. www.sciencedirect.com www.sciencedirect.com
    Sex-dependent effects in the aged melanoma tumor microenvironment influence invasion and resistance to targeted therapy
    1
    1. scibot 10 Sep 2024
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    sciencedirect.com/science/article/pii/S0092867424009048
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Resistance Training Diminishes Mitochondrial Adaptations to Subsequent Endurance Training in Healthy Untrained Men
    1
    1. scibot 06 Sep 2024
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      DOI: 10.1113/JP284822

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    ncbi.nlm.nih.gov/pmc/articles/PMC11062412/
  13. Aug 2024
  14. www.cell.com www.cell.com
    SLC25A48 controls mitochondrial choline import and metabolism
    1
    1. scibot 20 Aug 2024
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    cell.com/cell-metabolism/fulltext/S1550-4131(24)00281-X
  15. onlinelibrary.wiley.com onlinelibrary.wiley.com
    A common variant in the iron regulatory gene (Hfe) alters the metabolic and transcriptional landscape in brain regions vulnerable to neurodegeneration
    1
    1. scibot 19 Aug 2024
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      DOI: 10.1111/jnc.16171

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    onlinelibrary.wiley.com/doi/10.1111/jnc.16171
  16. Jul 2024
  17. www.sciencedirect.com www.sciencedirect.com
    Single-nucleus transcriptomics identifies separate classes of UCP1 and futile cycle adipocytes
    1
    1. scibot 31 Jul 2024
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    sciencedirect.com/science/article/pii/S1550413124002766
  18. www.sciencedirect.com www.sciencedirect.com
    Hippocampal Warburg effect Mediates Hydrogen Sulfide-Ameliorated Diabetes-Associated Cognitive Dysfunction: Involving Promotion of Hippocampal Synaptic Plasticity
    1
    1. scibot 24 Jul 2024
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      DOI: 10.1016/j.neures.2024.07.002

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    sciencedirect.com/science/article/pii/S0168010224000877
  19. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Metabolomics of repetitive myocardial stunning in chronic multivessel coronary artery stenosis: Effect of non-selective and selective β1-receptor blockers
    1
    1. scibot 18 Jul 2024
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      DOI: 10.1113/JP285720

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    physoc.onlinelibrary.wiley.com/doi/10.1113/JP285720
  20. dx.doi.org dx.doi.org
    Obese mice have decreased uterine contractility and altered energy metabolism in the uterus at term gestation
    1
    1. scibot 18 Jul 2024
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      DOI: 10.1093/biolre/ioae086

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    dx.doi.org/10.1093/biolre/ioae086
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    AMPK targets PDZD8 to trigger carbon source shift from glucose to glutamine
    1
    1. scibot 18 Jul 2024
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      DOI: 10.1038/s41422-024-00985-6

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    pmc.ncbi.nlm.nih.gov/articles/PMC11442470/
  22. www.sciencedirect.com www.sciencedirect.com
    Tumor suppressor KEAP1 promotes HSPA9 degradation, controlling mitochondrial biogenesis in breast cancer
    1
    1. scibot 16 Jul 2024
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      DOI: 10.1016/j.celrep.2024.114507

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    sciencedirect.com/science/article/pii/S2211124724008362
  23. Jun 2024
  24. www.cell.com www.cell.com
    Moderate-intensity aerobic exercise training improves CD8+ tumor-infiltrating lymphocytes effector function by reducing mitochondrial loss.
    1
    1. scibot 30 Jun 2024
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      DOI: 10.1016/j.isci.2024.110121

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    cell.com/iscience/abstract/S2589-0042(24)01346-4
  25. www.sciencedirect.com www.sciencedirect.com
    Insulin and leptin oscillations license food-entrained browning and metabolic flexibility
    1
    1. scibot 21 Jun 2024
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      DOI: 10.1016/j.celrep.2024.114390

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    sciencedirect.com/science/article/pii/S2211124724007186
  26. May 2024
  27. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Differential impact of sex on regulation of skeletal muscle mitochondrial function and protein homeostasis by hypoxia-inducible factor-1α in normoxia
    1
    1. scibot 25 May 2024
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      DOI: 10.1113/JP285339

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    physoc.onlinelibrary.wiley.com/doi/10.1113/JP285339
  28. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Monocarboxylate transporter 4 deficiency enhances high-intensity interval training-induced metabolic adaptations in skeletal muscle
    1
    1. scibot 24 May 2024
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      DOI: 10.1113/JP285719

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    physoc.onlinelibrary.wiley.com/doi/10.1113/JP285719
  29. www.sciencedirect.com www.sciencedirect.com
    SDHAF1 confers metabolic resilience to aging hematopoietic stem cells by promoting mitochondrial ATP production
    1
    1. scibot 21 May 2024
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      DOI: 10.1016/j.stem.2024.04.023

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    sciencedirect.com/science/article/pii/S1934590924001760
  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SIN-3 transcriptional coregulator maintains mitochondrial homeostasis and polyamine flux
    1
    1. scibot 10 May 2024
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      DOI: 10.1016/j.isci.2024.109789

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    pmc.ncbi.nlm.nih.gov/articles/PMC11091686/
  31. www.biorxiv.org www.biorxiv.org
    Deregulation of multiple mechanisms shapes the onset of LAMA2-congenital muscular dystrophy
    1
    1. scibot 03 May 2024
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      DOI: 10.1101/2024.01.20.576409

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    biorxiv.org/content/10.1101/2024.01.20.576409v1
  32. Apr 2024
  33. link.springer.com link.springer.com
    Mitovesicles secreted into the extracellular space of brains with mitochondrial dysfunction impair synaptic plasticity
    1
    1. scibot 17 Apr 2024
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      DOI: 10.1186/s13024-024-00721-z

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    link.springer.com/article/10.1186/s13024-024-00721-z
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Daily fluctuations in blood glucose with normal aging are inversely related to hippocampal synaptic mitochondrial proteins
    1
    1. scibot 11 Apr 2024
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      DOI: 10.1016/j.nbas.2024.100116

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    ncbi.nlm.nih.gov/pmc/articles/PMC11002859/
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Creatine and low-dose lithium supplementation separately alter energy expenditure, body mass and adipose metabolism for the promotion of thermogenesis
    2
    1. scibot 03 Apr 2024
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      DOI: 10.1016/j.isci.2024.109468

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      DOI: 10.1016/j.isci.2024.109468

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    ncbi.nlm.nih.gov/pmc/articles/PMC10973579/
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitochondrial biogenesis in white adipose tissue mediated by JMJD1A-PGC-1 axis limits age-related metabolic disease
    1
    1. scibot 03 Apr 2024
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      DOI: 10.1016/j.isci.2024.109398

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    ncbi.nlm.nih.gov/pmc/articles/PMC10966194/
  37. Mar 2024
  38. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mustn1 is a smooth muscle cell-secreted microprotein that modulates skeletal muscle extracellular matrix composition
    1
    1. scibot 22 Mar 2024
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      DOI: 10.1016/j.molmet.2024.101912

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    pmc.ncbi.nlm.nih.gov/articles/PMC10950823/
  39. Feb 2024
  40. www.sciencedirect.com www.sciencedirect.com
    Coordinated metabolic responses to cyclophilin D deletion in the developing heart
    2
    1. scibot 29 Feb 2024
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      DOI: 10.1016/j.isci.2024.109157

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    sciencedirect.com/science/article/pii/S258900422400378X
  41. www.sciencedirect.com www.sciencedirect.com
    NEMF-mediated Listerin-independent mitochondrial translational surveillance by E3 ligase Pirh2 and mitochondrial protease ClpXP
    1
    1. scibot 29 Feb 2024
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      DOI: 10.1016/j.celrep.2024.113860

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    sciencedirect.com/science/article/pii/S2211124724001888
  42. www.sciencedirect.com www.sciencedirect.com
    Flvcr1a deficiency promotes heme-based energy metabolism dysfunction in skeletal muscle
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      DOI: 10.1016/j.celrep.2024.113854

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    sciencedirect.com/science/article/pii/S2211124724001827
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SEPN1-related myopathy depends on the oxidoreductase ERO1A and is druggable with the chemical chaperone TUDCA
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      DOI: 10.1016/j.xcrm.2024.101439

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    ncbi.nlm.nih.gov/pmc/articles/PMC10982971/
  44. 52.53.155.43 52.53.155.43
    Loss of STIM2 in colorectal cancer drives growth and metastasis through metabolic reprogramming and PERK-ATF4 endoplasmic reticulum stress pathway
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      DOI: 10.1101/2023.10.02.560521

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    52.53.155.43/4a182fdd92d1ce35b13f136f7657c6c9ec6a6224/2023.10.02.560521v1.full-html.html
  45. 52.53.155.43 52.53.155.43
    Exercise training adaptations in liver glycogen and glycerolipids require hepatic AMP-activated protein kinase in mice
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      DOI: 10.1101/2023.09.01.555935

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    52.53.155.43/fd6bbeebd50ae2c0912f6e8604e8bc905b0c2518/2023.09.01.555935v1.full-html.html
  46. www.sciencedirect.com www.sciencedirect.com
    SLC25A51 decouples the mitochondrial NAD+/NADH ratio to control proliferation of AML cells
    3
    1. scibot 15 Feb 2024
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    sciencedirect.com/science/article/pii/S1550413124000135
  47. link.springer.com link.springer.com
    Neuronal cell-based high-throughput screen for enhancers of mitochondrial function reveals luteolin as a modulator of mitochondria-endoplasmic reticulum coupling
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      DOI: 10.1186/s12915-021-00979-5

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  48. Jan 2024
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    Loss of hepatic phosphoenolpyruvate carboxykinase 1 dysregulates metabolic responses to acute exercise but enhances adaptations to exercise training in mice
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  51. Dec 2023
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    MCUb is an inducible regulator of calcium-dependent mitochondrial metabolism and substrate utilization in muscle
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  53. Nov 2023
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    Adipo-glial signaling mediates metabolic adaptation in peripheral nerve regeneration
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    Skeletal muscle endurance declines with impaired mitochondrial respiration and inadequate supply of acetyl-CoA during muscle fatigue in 5/6 nephrectomized rats
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    Skeletal muscle endurance declines with impaired mitochondrial respiration and inadequate supply of acetyl-CoA during muscle fatigue in 5/6 nephrectomized rats
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    Effects of Exercise Training on Mitochondrial Fatty Acid β-Oxidation in the Kidneys of Dahl Salt-Sensitive Rats
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  58. Oct 2023
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    Physical exercise elicits UPRmt in the skeletal muscle: The role of c-Jun N-terminal kinase
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  61. Sep 2023
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    Regulatory T cells require IL6 receptor alpha signaling to control skeletal muscle function and regeneration
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    Sphingosine Kinase 1 is Involved in Triglyceride Breakdown by Maintaining Lysosomal Integrity in Brown Adipocytes
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  64. Aug 2023
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    Autophagy ablation in skeletal muscles worsens sepsis-induced muscle wasting, impairs whole-body metabolism, and decreases survival.
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  69. Jul 2023
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    5‐Hydroxymethylfurfural reduces skeletal muscle superoxide production and modifies force production in rats exposed to hypobaric hypoxia
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  73. Jun 2023
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  77. May 2023
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    Restoration of lysosomal acidification rescues autophagy and metabolic dysfunction in non-alcoholic fatty liver disease
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    Pyruvate-supported flux through medium-chain ketothiolase promotes mitochondrial lipid tolerance in cardiac and skeletal muscles
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    Role of parvalbumin in fatigue-induced changes in force and cytosolic calcium transients in intact single mouse myofibers
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    Linoleic acid potentiates CD8+ T cell metabolic fitness and antitumor immunity
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  88. Feb 2023
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    Correction: Dichotomous role of the human mitochondrial Na+/Ca2+/Li+ exchanger NCLX in colorectal cancer growth and metastasis
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    Isolation of extracellular fluids reveals novel secreted bioactive proteins from muscle and fat tissues
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    Effects of aging and long‐term physical activity on mitochondrial physiology and redox state of the cortex and cerebellum of female rats
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    Blocking AMPK β1 myristoylation enhances AMPK activity and protects mice from high-fat diet-induced obesity and hepatic steatosis
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    VLDL-VLDLR axis facilitates brown fat thermogenesis through replenishment of lipid fuels and PPARβ/δ activation
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    Lipolysis-derived linoleic acid drives beige fat progenitor cell proliferation
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    Downregulation of hepatic ceruloplasmin ameliorates NAFLD via SCO1-AMPK-LKB1 complex
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    Combinatorial treatment with exercise and AICAR potentiates the rescue of myotonic dystrophy type 1 mouse muscles in a sex-specific manner
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  102. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  103. www.sciencedirect.com www.sciencedirect.com
    Regional heterogeneity in mitochondrial function underlies region specific vulnerability in human brain ageing: Implications for neurodegeneration
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  104. Sep 2022
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  106. Aug 2022
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    TFAM expression in brown adipocytes confers obesity resistance by secreting extracellular vesicles that promote self-activation
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    Cardiac ultrastructure inspired matrix induces advanced metabolic and functional maturation of differentiated human cardiomyocytes
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  109. Jul 2022
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    Obese Skeletal Muscle-Expressed Interferon Regulatory Factor 4 Transcriptionally Regulates Mitochondrial Branched-Chain Aminotransferase Reprogramming Metabolome
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  111. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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  112. Jun 2022
  113. 52.53.155.43 52.53.155.43
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    Uncoupling protein 2 and aldolase B impact insulin release by modulating mitochondrial function and Ca2+ release from the ER
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  115. May 2022
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    Urolithin A improves muscle strength, exercise performance, and biomarkers of mitochondrial health in a randomized trial in middle-aged adults
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    IP3R-mediated Ca2+ signaling controls B cell proliferation through metabolic reprogramming
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    Adipose Mitochondrial Complex I Deficiency Modulates Inflammation and Glucose Homeostasis in a Sex-Dependent Manner
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    Uncompensated mitochondrial oxidative stress underlies heart failure in an iPSC-derived model of congenital heart disease
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  121. Mar 2022
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    Cell-autonomous control of intracellular temperature by unsaturation of phospholipid acyl chains
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  124. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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  126. Feb 2022
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    Probiotics counteract hepatic steatosis caused by ketogenic diet and upregulate AMPK signaling in a model of infantile epilepsy
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    The early reduction of left ventricular mass after sleeve gastrectomy depends on the fall of branched-chain amino acid circulating levels
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  129. Jan 2022
  130. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    Nicotinamide riboside supplementation confers marginal metabolic benefits in obese mice without remodeling the muscle acetyl-proteome
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  132. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Skeletal muscle NOX4 is required for adaptive responses that prevent insulin resistance
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      DOI: 10.1126/sciadv.abl4988

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  133. Dec 2021
  134. www.science.org www.science.org
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    NAD kinase sustains lipogenesis and mitochondrial metabolismthrough fatty acid synthesis
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    Intrauterine growth restriction elevates circulating acylcarnitines and suppresses fatty-acid metabolism genes in the fetal sheep heart
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    Defective brown adipose tissue thermogenesis and impaired glucose metabolism in mice lacking Letmd1
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    Cysteine 253 of UCP1 regulates energy expenditure and sex-dependent adipose tissue inflammation
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  139. Nov 2021
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    APOL1 risk variants in individuals of African genetic ancestry drive endothelial cell defects that exacerbate sepsis
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  141. Oct 2021
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    Changes in PGC-1α-Dependent Mitochondrial Biogenesis Are Associated with Inflexible Hepatic Energy Metabolism in the Offspring Born to Dexamethasone-Treated Mothers
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    MACF1 controls skeletal muscle function through the microtubule-dependent localization of extra-synaptic myonuclei and mitochondria biogenesis
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  145. Sep 2021
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    Muscle-secreted neurturin couples myofiber oxidative metabolism and slow motor neuron identity
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    Skeletal muscle type-specific mitochondrial adaptation to high-fat diet relies on differential autophagy modulation
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    Brown adipocyte ATF4 activation improves thermoregulation and systemic metabolism
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    The thermogenic activity of adjacent adipocytes fuels the progression of ccRCC and compromises anti-tumor therapeutic efficacy
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  150. Aug 2021
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  152. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    Targeting metabolic plasticity in glioma stem cells in vitro and in vivo through specific inhibition of c-Src by TAT-Cx43266-283
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    Dynamic Cardiolipin Synthesis Is Required for CD8+ T Cell Immunity
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  201. Nov 2020
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    CRISPR-Mediated Induction of Neuron-Enriched Mitochondrial Proteins Boosts Direct Glia-to-Neuron Conversion
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    Prdm16 Deficiency Leads to Age-Dependent Cardiac Hypertrophy, Adverse Remodeling, Mitochondrial Dysfunction, and Heart Failure
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  205. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
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    Dichotomous role of the human mitochondrial Na+/Ca2+/Li+ exchanger NCLX in colorectal cancer growth and metastasis
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  207. Sep 2020
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    Single Nucleotide Resolution Analysis Reveals Pervasive, Long-Lasting DNA Methylation Changes by Developmental Exposure to a Mitochondrial Toxicant
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  210. elifesciences.org elifesciences.org
    Transcriptomic and proteomic landscape of mitochondrial dysfunction reveals secondary coenzyme Q deficiency in mammals
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    Astaxanthin attenuates hepatic damages and mitochondrial dysfunction in nonalcoholic fatty liver disease by up‐regulating the FGF21/PGC‐1α pathway
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    Mitophagy, Autophagy and Cell Death: The novel cyclophilin-D-interacting protein FASTKD1 protects cells against oxidative stress-induced cell death
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    The oligosaccharide portion of ganglioside GM1 regulates mitochondrial function in neuroblastoma cells
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    Iron deficiency‐induced loss of skeletal muscle mitochondrial proteins and respiratory capacity; the role of mitophagy and secretion of mitochondria‐containing vesicles
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    Defective Mitochondrial Pyruvate Flux Affects Cell Bioenergetics in Alzheimer’s Disease-Related Models
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    Succinate Can Shuttle Reducing Power from the Hypoxic Retina to the O2-Rich Pigment Epithelium
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    Metabolic reprogramming of fibro/adipogenic progenitors facilitates muscle regeneration
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    A Mouse Homolog of a Human TP53 Germline Mutation Reveals a Lipolytic Activity of p53
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    Mitochondrial Membrane Potential Regulates Nuclear Gene Expression in Macrophages Exposed to Prostaglandin E2
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  222. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Liver CPT1A gene therapy reduces diet‐induced hepatic steatosis in mice and highlights potential lipid biomarkers for human NAFLD
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      Total OXPHOS Rodent WB Antibody Cocktail

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    Low-density lipoprotein receptor-related protein 1 deficiency in cardiomyocytes reduces susceptibility to insulin resistance and obesity
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  224. journals.physiology.org journals.physiology.org
    Lower oxygen consumption and Complex I activity in mitochondria isolated from skeletal muscle of fetal sheep with intrauterine growth restriction | American Journal of Physiology-Endocrinology and Metabolism
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    Shared PPARα/γ Target Genes Regulate Brown Adipocyte Thermogenic Function
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  226. Jan 2020
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    Impaired skeletal muscle mitochondrial pyruvate uptake rewires glucose metabolism to drive whole-body leanness
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    MitoRibo-Tag Mice Provide a Tool for In Vivo Studies of Mitoribosome Composition
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  229. diabetes.diabetesjournals.org diabetes.diabetesjournals.org
    Differential effect of glucose on ER-mitochondria Ca2+ exchange participates to insulin secretion and to glucotoxicity-mediated dysfunction of β cells.
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    Mitochondrial Damage and Activation of the STING Pathway Lead to Renal Inflammation and Fibrosis
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    Bioavailability and cytosolic kinases modulate response to deoxynucleoside therapy in TK2 deficiency
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    UCP2 Deficiency Increases Colon Tumorigenesis by Promoting Lipid Synthesis and Depleting NADPH for Antioxidant Defenses
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    Bilirubin Links Heme Metabolism to Neuroprotection by Scavenging Superoxide
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    The RNA-Binding Protein PUM2 Impairs Mitochondrial Dynamics and Mitophagy During Aging
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    Chronic fetal hypoxia disrupts the peri‐conceptual environment in next‐generation adult female rats
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      DOI: 10.1113/JP277431

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