73 Matching Annotations
  1. Mar 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Iron overload in hypothalamic AgRP neurons contributes to obesity and related metabolic disorders
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    sciencedirect.com/science/article/pii/S2211124724002286
  3. Jan 2024
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MIIP downregulation drives colorectal cancer progression through inducing peri-cancerous adipose tissue browning
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    ncbi.nlm.nih.gov/pmc/articles/PMC10800076/
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    miRNA-194-3p represses NF-κB in gliomas to attenuate iPSC genes and proneural to mesenchymal transition.
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    1. scibot 18 Jan 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC10788216/
  6. Dec 2023
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    A desmosomal cadherin controls multipotent hair follicle stem cell quiescence and orchestrates regeneration through adhesion signaling
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    sciencedirect.com/science/article/pii/S2589004223026457
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    Apoptosis releases hydrogen sulfide to inhibit Th17 cell differentiation
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    1. scibot 19 Dec 2023
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    sciencedirect.com/science/article/pii/S1550413123004448
  9. Nov 2023
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    AGC kinase inhibitors regulate STING signaling through SGK-dependent and SGK-independent mechanisms
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    1. scibot 28 Nov 2023
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    sciencedirect.com/science/article/abs/pii/S2451945623003690
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    Adipo-glial signaling mediates metabolic adaptation in peripheral nerve regeneration
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    sciencedirect.com/science/article/pii/S1550413123003868
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    Detection of early prognostic biomarkers for metastasis of Ewing's sarcoma in pediatric patients
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    sciencedirect.com/science/article/pii/S002432052300872X
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    Large-scale production of human blastoids amenable to modeling blastocyst development and maternal-fetal cross talk
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    sciencedirect.com/science/article/pii/S1934590923002850
  14. Sep 2023
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Crizotinib has Preclinical Efficacy in Philadelphia-negative Myeloproliferative Neoplasms
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    ncbi.nlm.nih.gov/pmc/articles/PMC9992133/
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    In vivo modeling of CLL transformation to Richter’s syndrome reveals convergent evolutionary paths and therapeutic vulnerabilities
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  17. Aug 2023
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting Bcl-xL is a potential therapeutic strategy for extranodal NK/T cell lymphoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10393801/
  19. Jun 2023
  20. www.sciencedirect.com www.sciencedirect.com
    New scaffolds for type II JAK2 inhibitors overcome the acquired G993A resistance mutation
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  21. May 2023
  22. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.16780
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Potential targets and mechanisms of photobiomodulation for... : Neural Regeneration Research
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    ncbi.nlm.nih.gov/pmc/articles/PMC10154481/
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    DUSP4 promotes esophageal squamous cell carcinoma progression by dephosphorylating HSP90β
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    sciencedirect.com/science/article/pii/S2211124723004564
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    Cross-activation of FGF, NODAL, and WNT pathways constrains BMP-signaling-mediated induction of the totipotent state in mouse embryonic stem cells
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    sciencedirect.com/science/article/pii/S2211124723004497
  26. Apr 2023
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    The RNA editor ADAR2 promotes immune cell trafficking by enhancing endothelial responses to interleukin-6 during sterile inflammation
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    sciencedirect.com/science/article/pii/S1074761323001413
  28. Mar 2023
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Restricting genomic actions of innate immune mediators on fetal hematopoietic progenitor cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10025987/
  30. 52.53.155.43 52.53.155.43
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    Estradiol regulates leptin sensitivity to control feeding via hypothalamic Cited1
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    sciencedirect.com/science/article/pii/S1550413123000402
  32. Feb 2023
  33. academic.oup.com academic.oup.com
    Genetic Val66Met BDNF Variant Increases Hyperphagia on Fat-rich Diets in Mice
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      DOI: 10.1210/endocr/bqad008

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    academic.oup.com/endo/article/164/3/bqad008/6984997
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    Beta-coronaviruses exploit cellular stress responses by modulating TFEB and TFE3 activity
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  35. 52.53.155.43 52.53.155.43
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  36. Oct 2022
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Prdm14 promotes mouse ESC self-renewal and PGCLC specification through enhancement of Stat3 activity
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    ncbi.nlm.nih.gov/pmc/articles/PMC9589213/
  38. Aug 2022
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    STAT6 in mitochondrial outer membrane impairs mitochondrial fusion by inhibiting MFN2 dimerization
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    sciencedirect.com/science/article/pii/S2589004222011956
  40. Jul 2022
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-Wide CRISPR Screening Identifies DCK and CCNL1 as Genes That Contribute to Gemcitabine Resistance in Pancreatic Cancer
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      DOI: 10.3390/cancers14133152

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    ncbi.nlm.nih.gov/pmc/articles/PMC9264918/
  42. Jun 2022
  43. www.nature.com www.nature.com
    Umami-induced obesity and metabolic syndrome is mediated by nucleotide degradation and uric acid generation
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      DOI: 10.1038/s42255-021-00454-z

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    nature.com/articles/s42255-021-00454-z
  44. Apr 2022
  45. www.nature.com www.nature.com
    Identifying a confused cell identity for esophageal squamous cell carcinoma
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    nature.com/articles/s41392-022-00946-8
  46. Feb 2022
  47. www.sciencedirect.com www.sciencedirect.com
    Identification of serum and glucocorticoid-regulated kinase 1 as a regulator of signal transducer and activator of transcription 3 signaling
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      #12640; Cell Signaling Technology

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    sciencedirect.com/science/article/pii/S0014482722000726
  48. Dec 2021
  49. link.springer.com link.springer.com
    PDIA3 inhibits mitochondrial respiratory function in brain endothelial cells and C. elegans through STAT3 signaling and decreases survival after OGD
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  50. Oct 2021
  51. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15652
  52. Sep 2021
  53. journals.sagepub.com journals.sagepub.com
    Nitric Oxide Induces a Janus Kinase-1-Dependent Inflammatory Response in Primary Murine Astrocytes - John D. Nowery, Rylee N. Cisney, Jacob W. Feldmann, Gordon P. Meares, 2021
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      DOI: 10.1177/17590914211033650

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    journals.sagepub.com/doi/full/10.1177/17590914211033650
  54. Aug 2021
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sugar causes obesity and metabolic syndrome in mice independently of sweet taste
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      DOI: 10.1152/ajpendo.00529.2019

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    ncbi.nlm.nih.gov/pmc/articles/PMC7473911/
  56. Jul 2021
  57. www.sciencedirect.com www.sciencedirect.com
    Establishment, maintenance, and recall of inflammatory memory
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      DOI: 10.1016/j.stem.2021.07.001

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    sciencedirect.com/science/article/pii/S1934590921002861
  58. elifesciences.org elifesciences.org
    A comprehensive analysis of coregulator recruitment, androgen receptor function and gene expression in prostate cancer
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      12640

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    elifesciences.org/articles/28482
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lower androgen levels promote abnormal cartilage development in female patients with adolescent idiopathic scoliosis
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      DOI: 10.21037/atm-20-3171

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    ncbi.nlm.nih.gov/pmc/articles/PMC8246169/
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    Coupling of GPR30 mediated neurogenesis and protection with astroglial Aromatase-STAT3 signaling in rat hippocampus after global cerebral ischemia
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    sciencedirect.com/science/article/pii/S0303720721002380
  61. Jun 2021
  62. www.hindawi.com www.hindawi.com
    Table 2 | Saussureae Radix Attenuates Neuroinflammation in LPS-Stimulated Mouse BV2 Microglia via HO-1/Nrf-2 Induction and Inflammatory Pathway Inhibition
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  63. www.sciencedirect.com www.sciencedirect.com
    Uncovering the RNA-binding protein landscape in the pluripotency network of human embryonic stem cells
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  64. May 2021
  65. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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  66. www.sciencedirect.com www.sciencedirect.com
    Insulin- and Lipopolysaccharide-Mediated Signaling in Adipose Tissue Macrophages Regulates Postprandial Glycemia through Akt-mTOR Activation
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  67. Apr 2021
  68. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Nanog is a promising chemo‐resistant stemness marker and therapeutic target by iron chelators for esophageal cancer
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      anti‐STAT3

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  69. Mar 2021
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    PRMT6 methylation of RCC1 regulates mitosis, tumorigenicity, and radiation response of glioblastoma stem cells
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  71. Feb 2021
  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transneuronal delivery of hyper-interleukin-6 enables functional recovery after severe spinal cord injury in mice
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  73. elifesciences.org elifesciences.org
    Def6 regulates endogenous type-I interferon responses in osteoblasts and suppresses osteogenesis
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  74. www.authorea.com www.authorea.com
    Natural Product Trienomycin A is a STAT3 pathway inhibitor that exhibits potent in vitro and in vivo efficacy against pancreatic cancer
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  75. www.embopress.org www.embopress.org
    STAT3‐dependent analysis reveals PDK4 as independent predictor of recurrence in prostate cancer
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    MyD88 in myofibroblasts enhances colitis-associated tumorigenesis via promoting macrophage M2 polarization
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  77. Oct 2020
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    Sphingosylphosphorylcholine alleviates hypoxia-caused apoptosis in cardiac myofibroblasts via CaM/p38/STAT3 pathway
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  79. www.cell.com www.cell.com
    Metabolic Reprograming via Deletion of CISH in Human iPSC-Derived NK Cells Promotes In Vivo Persistence and Enhances Anti-tumor Activity
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  80. Sep 2020
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    Molecular Stressors Engender Protein Connectivity Dysfunction through Aberrant N-Glycosylation of a Chaperone
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    A Bartonella Effector Acts as Signaling Hub for Intrinsic STAT3 Activation to Trigger Anti-inflammatory Responses
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  83. journals.physiology.org journals.physiology.org
    Sugar causes obesity and metabolic syndrome in mice independently of sweet taste | American Journal of Physiology-Endocrinology and Metabolism
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  84. Jan 2020
  85. www.sciencedirect.com www.sciencedirect.com
    Lactate Buildup at the Site of Chronic Inflammation Promotes Disease by Inducing CD4+ T Cell Metabolic Rewiring
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    The Oncogenic Kaposi’s Sarcoma-Associated Herpesvirus Encodes a Mimic of the Tumor-Suppressive miR-15/16 miRNA Family
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  87. jcs.biologists.org jcs.biologists.org
    Blood vitronectin is a major activator of LIF and IL-6 in the brain through integrin–FAK and uPAR signaling
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      DOI: 10.1242/jcs.202580

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  88. www.eneuro.org www.eneuro.org
    Nociceptor deletion of Tsc2 enhances axon regeneration by inducing a conditioning injury response in dorsal root ganglia
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      DOI: 10.1523/ENEURO.0168-19.2019

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    Identification of a Small Compound Targeting PKM2-Regulated Signaling Using 2D Gel Electrophoresis-Based Proteome-wide CETSA
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      DOI: 10.1016/j.chembiol.2019.11.010

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    Salmonella Effector SteE Converts the Mammalian Serine/Threonine Kinase GSK3 into a Tyrosine Kinase to Direct Macrophage Polarization
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      DOI: 10.1016/j.chom.2019.11.002

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    A Potent and Selective Small-Molecule Degrader of STAT3 Achieves Complete Tumor Regression In Vivo
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  92. academic.oup.com academic.oup.com
    MAPK Erk5 in leptin receptor-expressing neurons controls body weight and systemic energy homeostasis in female mice
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      DOI: 10.1210/en.2019-00090

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    A GPR17-cAMP-Lactate Signaling Axis in Oligodendrocytes Regulates Whole-Body Metabolism
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    Amino alkynylisoquinoline and alkynylnaphthyridine compounds potently inhibit acute myeloid leukemia proliferation in mice
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  99. Nov 2018
  100. www.sciencedirect.com www.sciencedirect.com
    Liver Cancer Initiation Requires p53 Inhibition by CD44-Enhanced Growth Factor Signaling
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    Fas Promotes T Helper 17 Cell Differentiation and Inhibits T Helper 1 Cell Development by Binding and Sequestering Transcription Factor STAT1
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    The control of oligodendrocyte bioenergetics by interferon-gamma (IFN-γ) and Src homology region 2 domain-containing phosphatase-1 (SHP-1)
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