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Microglia with distinct origins and non-canonical phenotypes coexist within the border-like niche of the brain’s circumventricular organs

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1. scibot 01 Oct 2026
  
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  DOI: 10.1016/j.immuni.2026.09.002
  
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sciencedirect.com/science/article/pii/S1074761326003778
Jul 2026
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Repurposed ethoxzolamide reprograms antitumor immunity through β-TrCP-dependent PD-L1 ubiquitination

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1. scibot 14 Jul 2026
  
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  DOI: 10.1016/j.xcrm.2026.102920
  
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sciencedirect.com/science/article/pii/S266637912600337X
aacrjournals.org aacrjournals.org

Tumor-Associated Macrophages Produce PGE2 to Promote CD8+ T Cell Exhaustion and Drive Resistance to PD-L1 Blockade in Microsatellite Stable Colorectal Cancer

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1. scibot 11 Jul 2026
  
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  AB_2629637
  
  DOI: 10.1158/0008-5472.CAN-25-0079
  
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aacrjournals.org/cancerres/article/86/3/785/771916/Tumor-Associated-Macrophages-Produce-PGE2-to
Apr 2026
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Wheat fiber mitigates colitis via non-SCFA microbial metabolite-trained intestinal macrophages

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1. scibot 01 Apr 2026
  
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  DOI: 10.1126/sciadv.aec5757
  
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science.org/doi/10.1126/sciadv.aec5757
Mar 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Wheat fiber mitigates colitis via non-SCFA microbial metabolite-trained intestinal macrophages

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1. scibot 27 Mar 2026
  
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  DOI: 10.1126/sciadv.aec5757
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13015863/
Sep 2025
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Mapping the genetic landscape establishing a tumor immune microenvironment favorable for anti-PD-1 response

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1. scibot 06 Sep 2025
  
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  DOI: 10.1016/j.celrep.2025.115698
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12404271/
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Zeaxanthin augments CD8+ effector T cell function and immunotherapy efficacy

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1. scibot 03 Sep 2025
  
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  DOI: 10.1016/j.xcrm.2025.102324
  
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sciencedirect.com/science/article/pii/S2666379125003970
Jul 2025
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A mast cell receptor mediates post-stroke brain inflammation via a dural-brain axis

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1. scibot 25 Jul 2025
  
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  DOI: 10.1016/j.cell.2025.06.045
  
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sciencedirect.com/science/article/pii/S0092867425007470
May 2025
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Monocytes can efficiently replace all brain macrophages and fetal liver monocytes can generate bona fide SALL1+ microglia

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1. scibot 17 May 2025
  
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  DOI: 10.1016/j.immuni.2025.04.006
  
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sciencedirect.com/science/article/pii/S1074761325001694
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Interleukin-34-dependent perivascular macrophages promote vascular function in the brain

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1. scibot 17 May 2025
  
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  DOI: 10.1016/j.immuni.2025.04.003
  
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sciencedirect.com/science/article/pii/S1074761325001669
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Regulatory T cells suppress GM-CSF-producing T helper cells via IL-2 modulation to restrain immunopathology

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1. scibot 16 May 2025
  
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  DOI: 10.1016/j.celrep.2025.115642
  
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sciencedirect.com/science/article/pii/S2211124725004139
Apr 2025
elifesciences.org elifesciences.org

Targeting IRE1α improves insulin sensitivity and thermogenesis and suppresses metabolically active adipose tissue macrophages in male obese mice

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1. scibot 19 Apr 2025
  
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  DOI: 10.7554/eLife.100581
  
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elifesciences.org/articles/100581
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Peripheral nervous system microglia-like cells regulate neuronal soma size throughout evolution

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1. scibot 08 Apr 2025
  
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  DOI: 10.1016/j.cell.2025.02.007
  
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sciencedirect.com/science/article/pii/S0092867425001928
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Targeting the dendritic cell-secreted immunoregulatory cytokine CCL22 alleviates radioresistance

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1. scibot 02 Apr 2025
  
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  DOI: 10.1158/1078-0432.CCR-23-3616
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11444901/
Mar 2025
www.cell.com www.cell.com

Lysine vitcylation is a vitamin C-derived protein modification that enhances STAT1-mediated immune response

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1. scibot 04 Mar 2025
  
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  DOI: 10.1016/j.cell.2025.01.043
  
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cell.com/cell/abstract/S0092-8674(25)00145-X
Feb 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Reducing microglial lipid load enhances β amyloid phagocytosis in an Alzheimer’s disease mouse model

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1. scibot 08 Feb 2025
  
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  DOI: 10.1126/sciadv.adq6038
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11797491/
Dec 2024
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Targeting IRE1α improves insulin sensitivity and thermogenesis and suppresses metabolically active adipose tissue macrophages in obesity

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1. scibot 21 Dec 2024
  
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  RRID:AB_2629637
  
  DOI: 10.1101/2024.07.17.603931
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11275733/
52.53.155.43 52.53.155.43

Enhancing Immune Response and Survival in Hepatocellular Carcinoma with Novel Oncolytic Jurona Virus and Immune Checkpoint Blockade

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1. scibot 06 Dec 2024
  
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  DOI: 10.1016/j.omton.2024.200913
  
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52.53.155.43/b17d322494c44a28e0d2e52b4d7ea9e056092d31/Enhancing Immune Response and Survival in Hepatocellular Carcinoma with Novel Oncolytic Jurona Virus and Immune Checkpoint Blockade-html.html
Jul 2024
www.cell.com www.cell.com

Macrophages preserve endothelial cell specialization in the adrenal gland to modulate aldosterone secretion and blood pressure

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1. scibot 19 Jul 2024
  
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  DOI: 10.1016/j.celrep.2024.114395
  
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cell.com/cell-reports/fulltext/S2211-1247(24)00723-X
Apr 2024
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Jagged2 targeting in lung cancer activates anti-tumor immunity via Notch-induced functional reprogramming of tumor-associated macrophages

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1. scibot 18 Apr 2024
  
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  DOI: 10.1016/j.immuni.2024.03.020
  
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sciencedirect.com/science/article/pii/S1074761324001419
Jan 2024
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Integrative analysis of neuroblastoma by single-cell RNA sequencing identifies the NECTIN2-TIGIT axis as a target for immunotherapy

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1. scibot 11 Jan 2024
  
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  DOI: 10.1016/j.ccell.2023.12.008
  
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2. scibot 11 Jan 2024
  
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  RRID:AB_2629637
  
  DOI: 10.1016/j.ccell.2023.12.008
  
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sciencedirect.com/science/article/pii/S1535610823004361
Oct 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Microglia and CD206+ border-associated mouse macrophages maintain their embryonic origin during Alzheimer’s disease

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1. scibot 23 Oct 2021
  
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  DOI: 10.7554/eLife.71879
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8523151/
Apr 2021
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Single-Cell Mapping of Human Brain Cancer Reveals Tumor-Specific Instruction of Tissue-Invading Leukocytes

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1. scibot 23 Apr 2021
  
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  DOI: 10.1016/j.cell.2020.04.055
  
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sciencedirect.com/science/article/pii/S0092867420305614
Sep 2020
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Early Fate Defines Microglia and Non-parenchymal Brain Macrophage Development

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1. scibot 13 Sep 2020
  
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  DOI: 10.1016/j.cell.2020.03.021
  
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  RRIDCUR:Validated RRID:AB_2629637
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sciencedirect.com/science/article/pii/S009286742030283X