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Tucatinib alleviates postmenopausal osteoporosis by suppressing osteoclast differentiation via regulating the DRP1/NFATc1/CTSK signaling pathway

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  DOI: 10.1016/j.bcp.2026.117962
  
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sciencedirect.com/science/article/pii/S0006295226002959
Mar 2026
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Radiation-induced autophagy regulates fibroblast mitochondrial metabolism and crosstalk with triple-negative breast cancer cells

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1. scibot 17 Mar 2026
  
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  DOI: 10.1016/j.celrep.2026.117096
  
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sciencedirect.com/science/article/pii/S2211124726001749
Feb 2026
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Clec16a maintains definitive hematopoietic stem and progenitor cells via mitophagy

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1. scibot 20 Feb 2026
  
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  DOI: 10.1016/j.celrep.2026.116978
  
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p53 Drives Lung Cancer Regression through a TSC2/TFEB-dependent Senescence Program

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1. scibot 10 Feb 2026
  
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  DOI: 10.1158/2159-8290.CD-25-0525
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12877752/
Jan 2026
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Cyclophilin D suppresses colorectal cancer progression through the activation of an autophagy-mediated apoptotic pathway

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1. scibot 31 Jan 2026
  
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  DOI: 10.1038/s41598-025-33774-1
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12852878/
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FAM43A coordinates mtDNA replication and mitochondrial biogenesis in response to mtDNA depletion

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1. scibot 28 Jan 2026
  
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  DOI: 10.1083/jcb.202311082
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11770945/
Nov 2025
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COPS2 coordinates biphasic autophagy hijacking for non-lytic propagation of enveloped RNA viruses

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1. scibot 22 Nov 2025
  
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  DOI: 10.1016/j.celrep.2025.116594
  
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Stra8 links neuronal activity to inhibitory circuit protection in the adult mouse brain

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1. scibot 05 Nov 2025
  
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  DOI: 10.1016/j.celrep.2025.116513
  
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sciencedirect.com/science/article/pii/S2211124725012847
Sep 2025
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Impaired MAPT/tau-secretory lysosomes are linked to cognitive vulnerability in Alzheimer patients

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1. scibot 03 Sep 2025
  
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  DOI: 10.1080/15548627.2025.2552905
  
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tandfonline.com/doi/full/10.1080/15548627.2025.2552905
Aug 2025
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Artesunate mitigates acute pancreatitis by enhancing acinar zymophagy via modulating the NRF2-p62-Keap1 loop

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  DOI: 10.22541/au.175404080.04917407/v1
  
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authorea.com/users/951840/articles/1321154-artesunate-mitigates-acute-pancreatitis-by-enhancing-acinar-zymophagy-via-modulating-the-nrf2-p62-keap1-loop
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Autophagy suppresses the formation of hepatocyte-derived cancer-initiating ductular progenitor cells in the liver

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1. scibot 14 Aug 2025
  
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  DOI: 10.1126/sciadv.abf9141
  
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science.org/doi/10.1126/sciadv.abf9141
Jun 2025
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Triflumizole induces excessive reactive oxygen species, inhibits the GPR30/PI3K/AKT pathway, and triggers apoptosis and autophagy in GC-1 spermatogonia cells

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1. scibot 04 Jun 2025
  
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  DOI: 10.1016/j.pestbp.2025.106486
  
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sciencedirect.com/science/article/pii/S0048357525001993
May 2025
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mTOR inhibition in Q175 Huntington’s disease model mice facilitates neuronal autophagy and mutant huntingtin clearance

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1. scibot 22 May 2025
  
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  DOI: 10.7554/eLife.104979
  
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Inhibition of histone deacetylase 6 activity mitigates neurological impairment and post-hemorrhagic hydrocephalus after intraventricular hemorrhage by modulating pyroptosis and autophagy pathways

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1. scibot 21 May 2025
  
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  DOI: 10.1186/s12987-025-00658-5
  
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link.springer.com/article/10.1186/s12987-025-00658-5
Apr 2025
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LAMP2A-mediated neuronal hyperexcitability by enhancing NKAβ1 degradation underlies depression-induced allodynia

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  DOI: 10.1016/j.celrep.2025.115489
  
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sciencedirect.com/science/article/pii/S2211124725002608
Jan 2025
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Rickettsia parkeri forms extensive, stable contacts with the rough endoplasmic reticulum

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1. scibot 10 Jan 2025
  
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  DOI: 10.1083/jcb.202406122
  
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rupress.org/jcb/article/224/3/e202406122/277199/Rickettsia-parkeri-forms-extensive-stable-contacts
Dec 2024
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Mechanism of enhancing chemotherapy efficacy in pancreatic ductal adenocarcinoma with paricalcitol and hydroxychloroquine

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1. scibot 29 Dec 2024
  
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  DOI: 10.1016/j.xcrm.2024.101881
  
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cell.com/cell-reports-medicine/fulltext/S2666-3791(24)00652-9
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Circular RNAs trigger nonsense-mediated mRNA decay

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1. scibot 12 Dec 2024
  
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  DOI: 10.1016/j.molcel.2024.11.022
  
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sciencedirect.com/science/article/pii/S109727652400947X
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Unveiling the physiological impact of ESCRT-dependent autophagosome closure by targeting the VPS37A ubiquitin E2 variant-like domain

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  DOI: 10.1016/j.celrep.2024.115016
  
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Jul 2024
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Cell-specific Nav1.6 knockdown reduced astrocyte-derived Aβ by reverse Na+-Ca2+ transporter-mediated autophagy in alzheimer-like mice

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1. scibot 30 Jul 2024
  
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sciencedirect.com/science/article/pii/S2090123224003096
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Pro-survival signaling regulates lipophagy essential for multiple myeloma resistance to stress-induced death

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  DOI: 10.1016/j.celrep.2024.114445
  
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Jun 2024
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Sustained generation of neurons destined for neocortex with oxidative metabolic upregulation upon filamin abrogation

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  DOI: 10.1016/j.isci.2024.110199
  
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Cardioprotective effect of Cinnamamide derivative compound 10 against myocardial ischemia-reperfusion through regulating cardiac autophagy via Sirt1

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1. scibot 06 Jun 2024
  
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  DOI: 10.1016/j.biopha.2024.116819
  
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sciencedirect.com/science/article/pii/S0753332224007030
May 2024
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Differential impact of sex on regulation of skeletal muscle mitochondrial function and protein homeostasis by hypoxia-inducible factor-1α in normoxia

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1. scibot 25 May 2024
  
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  DOI: 10.1113/JP285339
  
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physoc.onlinelibrary.wiley.com/doi/10.1113/JP285339
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Adiponectin inhibits the progression of obesity-associated papillary thyroid carcinoma through autophagy

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1. scibot 22 May 2024
  
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  DOI: 10.1210/endocr/bqae030
  
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academic.oup.com/endo/article-abstract/165/5/bqae030/7630457
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ATG9B regulates bacterial internalization via actin rearrangement

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1. scibot 05 May 2024
  
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  DOI: 10.1016/j.isci.2024.109623
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11066431/
Apr 2024
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An autophagy program that promotes T cell egress from the lymph node controls responses to immune checkpoint blockade

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  DOI: 10.1016/j.celrep.2024.114020
  
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Mar 2024
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Poxvirus A51R proteins regulate microtubule stability and antagonize a cell-intrinsic antiviral response

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sciencedirect.com/science/article/pii/S2211124724002109
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Combinatorial selective ER-phagy remodels the ER during neurogenesis

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  DOI: 10.1038/s41556-024-01356-4
  
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nature.com/articles/s41556-024-01356-4
Feb 2024
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The iron chelator and OXPHOS inhibitor VLX600 induces mitophagy and an autophagy-dependent type of cell death in glioblastoma cells

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1. scibot 22 Feb 2024
  
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  DOI: 10.1152/ajpcell.00293.2023
  
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  DOI: 10.1152/ajpcell.00293.2023
  
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52.53.155.43/d532629e4f1cf755a6f5c302a21018f2c97350c4/reisbeck-et-al-2023-the-iron-chelator-and-oxphos-inhibitor-vlx600-induces-mitophagy-and-an-autophagy-dependent-type-of (1)-html.html
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The iron chelator and OXPHOS inhibitor VLX600 induces mitophagy and an autophagy-dependent type of cell death in glioblastoma cells

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1. scibot 16 Feb 2024
  
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  DOI: 10.1152/ajpcell.00293.2023
  
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journals.physiology.org/doi/10.1152/ajpcell.00293.2023
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The HIF transcription network exerts innate antiviral activity in neurons and limits brain inflammation

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1. scibot 16 Feb 2024
  
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  DOI: 10.1016/j.celrep.2024.113792
  
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sciencedirect.com/science/article/pii/S2211124724001207
Jan 2024
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Response to Bruton’s tyrosine kinase inhibitors in aggressive lymphomas linked to chronic selective autophagy

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1. scibot 12 Jan 2024
  
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  DOI: 10.1016/j.ccell.2023.12.019
  
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sciencedirect.com/science/article/pii/S1535610823004476
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Chronic hypoxia stabilizes 3βHSD1 via autophagy suppression

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1. scibot 11 Jan 2024
  
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  DOI: 10.1016/j.celrep.2023.113575
  
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Kidney organoid models reveal cilium-autophagy metabolic axis as a therapeutic target for PKD both in vitro and in vivo

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Sequestration of translation initiation factors in p62 condensates

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Macrophage autophagy deficiency-induced CEBPB accumulation alleviates atopic dermatitis via impairing M2 polarization

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Nuclear localization of STING1 competes with canonical signaling to activate AHR for commensal and intestinal homeostasis

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Blocking AMPKαS496 phosphorylation improves mitochondrial dynamics and hyperglycemia in aging and obesity

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Control of mitophagy initiation and progression by the TBK1 adaptors NAP1 and SINTBAD

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Heteronemin promotes iron-dependent cell death in pancreatic cancer

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Usp25-Erlin1/2 activity limits cholesterol flux to restrict virus infection

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PIIS2211124723009543-html.html

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Metabolic enzyme UAP1 mediates IRF3 pyrophosphorylation to facilitate innate immune response

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Palmitoylation prevents sustained inflammation by limiting NLRP3 inflammasome activation through chaperone-mediated autophagy

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Caspase-8 inactivation drives autophagy-dependent inflammasome activation in myeloid cells

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Estrogen receptor β activation inhibits colitis by promoting NLRP6-mediated autophagy

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Sox9 mediates Autophagy-dependent vascular smooth muscle cell phenotypic modulation and transplant arteriosclerosis

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The molecular network of the proteasome machinery inhibition response is orchestrated by HSP70, revealing vulnerabilities in cancer cells

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T cells mediate kidney tubular injury via impaired PDHA1 and Autophagy in type 1 diabetes

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Cholesterol suppresses GOLM1-dependent selective autophagy of RTKs in hepatocellular carcinoma

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A selective PPM1A inhibitor activates autophagy to restrict the survival of Mycobacterium tuberculosis

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MEK inhibition overcomes chemoimmunotherapy resistance by inducing CXCL10 in cancer cells

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m6A mRNA methylation-directed myeloid cell activation controls progression of NAFLD and obesity

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Temporal proteomics during neurogenesis reveals large-scale proteome and organelle remodeling via selective autophagy

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Humanin-induced autophagy plays important roles in skeletal muscle function and lifespan extension

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Roles of autophagy in relation to mitochondrial stress responses of HeLa cells to lamellarin cytotoxicity

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PKCλ/ι inhibition activates an ULK2-mediated interferon response to repress tumorigenesis

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Untitled document

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Autophagy modulates endothelial junctions to restrain neutrophil diapedesis during inflammation

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Neuronal VCP loss of function recapitulates FTLD-TDP pathology

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Intracellular H2S production is an autophagy-dependent adaptive response to DNA damage

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Autophagy suppresses the formation of hepatocyte-derived cancer-initiating ductular progenitor cells in the liver

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Mitocytosis, a migrasome-mediated mitochondrial quality-control process

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Paradoxical Mitophagy Regulation by PINK1 and TUFm

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Acetyl-CoA Derived from Hepatic Peroxisomal β-Oxidation Inhibits Autophagy and Promotes Steatosis via mTORC1 Activation

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In vivo screens using a selective CRISPR antigen removal lentiviral vector system reveal immune dependencies in renal cell carcinoma

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  DOI: 10.1016/j.immuni.2021.01.001
  
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Inositol Polyphosphate Multikinase Inhibits Liquid-Liquid Phase Separation of TFEB to Negatively Regulate Autophagy Activity

1
1. scibot 05 May 2021
  
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  DOI: 10.1016/j.devcel.2020.10.010
  
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Feb 2021
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Nestin protects podocyte from injury in lupus nephritis by mitophagy and oxidative stress

1
1. scibot 25 Feb 2021
  
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  DOI: 10.1038/s41419-020-2547-4
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7200703/
Jan 2021
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Protective effect of hydrogen sulfide on endothelial cells through Sirt1-FoxO1-mediated autophagy

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1. scibot 13 Jan 2021
  
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  DOI: 10.21037/atm-20-3647
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7791216/
Sep 2020
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Pharmacological enhancement of TFEB-mediated autophagy alleviated neuronal death in oxidative stress-induced Parkinson’s disease models

1
1. scibot 06 Sep 2020
  
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  DOI: 10.1038/s41419-020-2322-6
  
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Nestin protects podocyte from injury in lupus nephritis by mitophagy and oxidative stress

1
1. scibot 04 Sep 2020
  
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  RRID: AB_2630393
  
  DOI: 10.1038/s41419-020-2547-4
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7200703/
Jan 2020
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LC3-Associated Endocytosis Facilitates β-Amyloid Clearance and Mitigates Neurodegeneration in Murine Alzheimer’s Disease

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2630393
  
  DOI: 10.1016/j.cell.2019.05.056
  
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cell.com/cell/fulltext/S0092-8674(19)30627-0
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RAD51AP1 Is an Essential Mediator of Alternative Lengthening of Telomeres

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  RRID:AB_2630393
  
  DOI: 10.1016/j.molcel.2019.06.043
  
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Hantavirus Inhibits TRAIL-Mediated Killing of Infected Cells by Downregulating Death Receptor 5

1
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  RRID:AB_2630393
  
  DOI: 10.1016/j.celrep.2019.07.066
  
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Mitochondrial protein import is regulated by p17/PERMIT to mediate lipid metabolism and cellular stress

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  RRID:AB_2630393
  
  DOI: 10.1126/sciadv.aax1978
  
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advances.sciencemag.org/content/5/9/eaax1978
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KDM3A Senses Oxygen Availability to Regulate PGC-1α-Mediated Mitochondrial Biogenesis

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  RRID:AB_2630393
  
  DOI: 10.1016/j.molcel.2019.09.019
  
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Non-oncogene Addiction to SIRT3 Plays a Critical Role in Lymphomagenesis

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  RRID:AB_2630393
  
  DOI: 10.1016/j.ccell.2019.05.002
  
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Huntington’s Disease Pathogenesis Is Modified In Vivo by Alfy/Wdfy3 and Selective Macroautophagy

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2630393
  
  DOI: 10.1016/j.neuron.2019.12.003
  
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TEX264 Is an Endoplasmic Reticulum-Resident ATG8-Interacting Protein Critical for ER Remodeling during Nutrient Stress

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1. scibot 12 Jan 2020
  
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  RRID:AB_2630393
  
  DOI: 10.1016/j.molcel.2019.03.034
  
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Nov 2018
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LC3-Associated Phagocytosis in Myeloid Cells Promotes Tumor Immune Tolerance

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1. scibot 05 Nov 2018
  
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PINK1 and PARK2 Suppress Pancreatic Tumorigenesis through Control of Mitochondrial Iron-Mediated Immunometabolism

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AMPK-Mediated BECN1 Phosphorylation Promotes Ferroptosis by Directly Blocking System Xc– Activity

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europepmc.org europepmc.org

MST4 Phosphorylation of ATG4B Regulates Autophagic Activity, Tumorigenicity, and Radioresistance in Glioblastoma

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1. scibot 05 Nov 2018
  
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europepmc.org/articles/PMC5734934/
Nov 2017
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Tetherin Suppresses Type I Interferon Signaling by Targeting MAVS for NDP52-Mediated Selective Autophagic Degradation in Human Cells

1
1. scibot 08 Nov 2017
  
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Bromodomain Protein BRD4 Is a Transcriptional Repressor of Autophagy and Lysosomal Function

1
1. scibot 08 Nov 2017
  
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  Rabbit monoclonal anti-ATG5 (clone D5F5U)Cell Signaling TechnologyCat#: 12994S
  
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Autophagy inhibition overcomes multiple mechanisms of resistance to BRAF inhibition in brain tumors

2
1. scibot 08 Nov 2017
  
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  AB_2630393
  
  Curator: @gabimpine
  
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2. scibot 08 Nov 2017
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5241115/

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