91 Matching Annotations
  1. Jun 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Progenitor-like cells contributing to cellular heterogeneity in the nucleus pulposus are lost in intervertebral disc degeneration
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      DOI: 10.1016/j.celrep.2024.114342

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    sciencedirect.com/science/article/pii/S2211124724006703
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    Myocardial infarction accelerates the progression of MASH by triggering immunoinflammatory response and induction of periosti
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    sciencedirect.com/science/article/pii/S1550413124001761
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    Coordination between endoderm progression and mouse gastruloid elongation controls endodermal morphotype choice
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    1. scibot 05 Jun 2024
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    sciencedirect.com/science/article/pii/S1534580724003356
  5. May 2024
  6. 52.53.155.43 52.53.155.43
    2024.02.25.581951v1.full-html.html
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    1. scibot 16 May 2024
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      DOI: 10.1038/nature12362

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    52.53.155.43/3cbbb6c4022cb0d94766603ef526c2fd13dcbc89/2024.02.25.581951v1.full-html.html
  7. Apr 2024
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    Thbs1 regulates skeletal muscle mass in a TGFβ-Smad2/3-ATF4-dependent manner
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    1. scibot 30 Apr 2024
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    sciencedirect.com/science/article/pii/S2211124724004777
  9. Mar 2024
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dysregulated lysosomal exocytosis drives protease-mediated cartilage pathogenesis in multiple lysosomal disorders
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    1. scibot 19 Mar 2024
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      DOI: 10.1016/j.isci.2024.109293

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    ncbi.nlm.nih.gov/pmc/articles/PMC10940929/
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    Identification of key immune cells infiltrated in lung adenocarcinoma microenvironment and their related lncRNA
    2
    1. scibot 07 Mar 2024
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      DOI: 10.1016/j.isci.2024.109220

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    sciencedirect.com/science/article/pii/S2589004224004413
  12. Feb 2024
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    Growth differentiation factor 9 regulates the expression of estrogen receptors via Smad2/3 signaling in goat cumulus cells
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    1. scibot 23 Feb 2024
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      DOI: 10.1016/j.theriogenology.2024.02.021

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    sciencedirect.com/science/article/pii/S0093691X24000852
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    Sphingolipid metabolism controls mammalian heart regeneration
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    1. scibot 21 Feb 2024
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    sciencedirect.com/science/article/pii/S1550413124000172
  15. Dec 2023
  16. www.sciencedirect.com www.sciencedirect.com
    EGFR-activated myofibroblasts promote metastasis of pancreatic cancer
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    1. scibot 29 Dec 2023
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    sciencedirect.com/science/article/pii/S1535610823004300
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    An oncogenic phenoscape of colonic stem cell polarization
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    1. scibot 17 Dec 2023
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      DOI: 10.1016/j.cell.2023.11.004

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    sciencedirect.com/science/article/pii/S0092867423012217
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    Trellis tree-based analysis reveals stromal regulation of patient-derived organoid drug responses
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      DOI: 10.1016/j.cell.2023.11.005

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    sciencedirect.com/science/article/pii/S0092867423012205
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    Heterogeneity and transcriptional drivers of triple-negative breast cancer
    1
    1. scibot 16 Dec 2023
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      DOI: 10.1016/j.celrep.2023.113564

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    sciencedirect.com/science/article/pii/S2211124723015760
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    Smad4 sequestered in SFPQ condensates prevents TGF-β tumor-suppressive signaling
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    1. scibot 16 Dec 2023
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    sciencedirect.com/science/article/pii/S1534580723006184
  21. Nov 2023
  22. www.sciencedirect.com www.sciencedirect.com
    Deep learning untangles the resistance mechanism of p53 reactivator in lung cancer cells
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    1. scibot 29 Nov 2023
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      DOI: 10.1016/j.isci.2023.108377

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    sciencedirect.com/science/article/pii/S2589004223024549
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    TGFB1 induces fetal reprogramming and enhances intestinal regeneration
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    1. scibot 10 Nov 2023
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      DOI: 10.1016/j.stem.2023.09.015

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    sciencedirect.com/science/article/pii/S1934590923003624
  24. Sep 2023
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Combination of an ACLY inhibitor with a GLP-1R agonist exerts additive benefits on nonalcoholic steatohepatitis and hepatic fibrosis in mice
    1
    1. scibot 28 Sep 2023
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      DOI: 10.1016/j.xcrm.2023.101193

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    ncbi.nlm.nih.gov/pmc/articles/PMC10518624/
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    An improved Erk biosensor detects oscillatory Erk dynamics driven by mitotic erasure during early development
    1
    1. scibot 16 Sep 2023
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      DOI: 10.1016/j.devcel.2023.08.021

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    sciencedirect.com/science/article/pii/S1534580723004367
  27. Jul 2023
  28. 52.53.155.43 52.53.155.43
    British J Pharmacology - 2023 - Chen - Anthelmintics nitazoxanide protects against experimental pulmonary fibrosis-html.html
    2
    1. scibot 21 Jul 2023
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      DOI: 10.1111/bph.16190

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      DOI: 10.1111/bph.16190

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    52.53.155.43/01e7f498781407a431fc8d9b3b9cdd8be1437af6/British J Pharmacology - 2023 - Chen - Anthelmintics nitazoxanide protects against experimental pulmonary fibrosis-html.html
  29. May 2023
  30. www.sciencedirect.com www.sciencedirect.com
    Cross-activation of FGF, NODAL, and WNT pathways constrains BMP-signaling-mediated induction of the totipotent state in mouse embryonic stem cells
    1
    1. scibot 03 May 2023
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      DOI: 10.1016/j.celrep.2023.112438

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    sciencedirect.com/science/article/pii/S2211124723004497
  31. Apr 2023
  32. www.sciencedirect.com www.sciencedirect.com
    Protocol for analyzing transforming growth factor β signaling in dextran-sulfate-sodium-induced colitic mice using flow cytometry and western blotting
    1
    1. scibot 26 Apr 2023
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      DOI: 10.1016/j.xpro.2023.102249

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    sciencedirect.com/science/article/pii/S2666166723002071
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    Sp1-like protein KLF13 acts as a negative feedback regulator of TGF-β signaling and fibrosis
    1
    1. scibot 08 Apr 2023
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      DOI: 10.1016/j.celrep.2023.112367

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    sciencedirect.com/science/article/pii/S2211124723003789
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    Nodal coordinates the anterior-posterior patterning of germ layers and induces head formation in zebrafish explants
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      DOI: 10.1016/j.celrep.2023.112351

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    sciencedirect.com/science/article/pii/S2211124723003625
  35. Dec 2022
  36. www.sciencedirect.com www.sciencedirect.com
    Nodal signaling establishes a competency window for stochastic cell fate switching
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    1. scibot 06 Dec 2022
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      DOI: 10.1016/j.devcel.2022.11.008

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    sciencedirect.com/science/article/pii/S1534580722008085
  37. Nov 2022
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Combinatorial prophylactic effect of phlorotannins with photobiomodulation against tracheal stenosis
    1
    1. scibot 18 Nov 2022
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      DOI: 10.1016/j.isci.2022.105405

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    ncbi.nlm.nih.gov/pmc/articles/PMC9664362/
  39. Oct 2022
  40. elifesciences.org elifesciences.org
    Regulation of Nodal signaling propagation by receptor interactions and positive feedback
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    1. scibot 28 Oct 2022
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      DOI: 10.7554/eLife.66397

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    elifesciences.org/articles/66397
  41. journals.physiology.org journals.physiology.org
    Pathophysiological levels of GDF11 activate Smad2/Smad3 signaling and induce muscle atrophy in human iPSC-derived myocytes
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    1. scibot 25 Oct 2022
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      DOI: 10.1152/ajpcell.00341.2022

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    journals.physiology.org/doi/10.1152/ajpcell.00341.2022
  42. Aug 2022
  43. www.sciencedirect.com www.sciencedirect.com
    Arid1a mutation suppresses TGF-β signaling and induces cholangiocarcinoma
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      DOI: 10.1016/j.celrep.2022.111253

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    sciencedirect.com/science/article/pii/S2211124722010713
  44. Jul 2022
  45. www.sciencedirect.com www.sciencedirect.com
    Reciprocal SOX2 regulation by SMAD1-SMAD3 is critical for anoikis resistance and metastasis in cancer
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      DOI: 10.1016/j.celrep.2022.111066

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    sciencedirect.com/science/article/pii/S2211124722008646
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    HMCES modulates the transcriptional regulation of nodal/activin and BMP signaling in mESCs
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      DOI: 10.1016/j.celrep.2022.111038

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    sciencedirect.com/science/article/pii/S2211124722008324
  47. Mar 2022
  48. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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      DOI: 10.1111/bph.15786

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15786
  49. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    Aggravation of pulmonary fibrosis after knocking down the aryl hydrocarbon receptor in the insulin-like growth factor 1 receptor pathway
    1
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      DOI: 10.1111/bph.15806

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15806
  50. Feb 2022
  51. bmcbiol.biomedcentral.com bmcbiol.biomedcentral.com
    Competition between type I activin and BMP receptors for binding to ACVR2A regulates signaling to distinct Smad pathways
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      DOI: 10.1186/s12915-022-01252-z

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    bmcbiol.biomedcentral.com/articles/10.1186/s12915-022-01252-z
  52. Jan 2022
  53. www.sciencedirect.com www.sciencedirect.com
    Disruption of pancreatic stellate cell myofibroblast phenotype promotes pancreatic tumor invasion
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      DOI: 10.1016/j.celrep.2021.110227

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    sciencedirect.com/science/article/pii/S2211124721017319
  54. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    1. scibot 09 Jan 2022
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      DOI: 10.1111/bph.15636

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15636
  55. www.sciencedirect.com www.sciencedirect.com
    CXCL4 drives fibrosis by promoting several key cellular and molecular processes
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    1. scibot 05 Jan 2022
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      DOI: 10.1016/j.celrep.2021.110189

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    sciencedirect.com/science/article/pii/S2211124721016909
  56. Dec 2021
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Effect of miR-183-5p on Cholestatic Liver Fibrosis by Regulating Fork Head Box Protein O1 Expression
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    1. scibot 04 Dec 2021
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      DOI: 10.3389/fphys.2021.737313

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    ncbi.nlm.nih.gov/pmc/articles/PMC8639207/
  58. Nov 2021
  59. www.sciencedirect.com www.sciencedirect.com
    Statins affect cancer cell plasticity with distinct consequences for tumor progression and metastasis
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  61. Oct 2021
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    Therapeutic silencing of SMOC2 prevents kidney function loss in mouse model of chronic kidney disease
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  63. Sep 2021
  64. www.nature.com www.nature.com
    Pantoprazole ameliorates liver fibrosis and suppresses hepatic stellate cell activation in bile duct ligation rats by promoting YAP degradation
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  65. Aug 2021
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    Hormonally regulated myogenic miR-486 influences sex-specific differences in cancer-induced skeletal muscle defects
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    KDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance
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  69. Jul 2021
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    CD109 Restrains Activation of Cutaneous IL-17-Producing γδ T Cells by Commensal Microbiota
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      Phospho-smad2 (Ser465/467)/Smad3 (Ser423/425) Rabbit mAb (D27F4)

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    Neuroplasticity and inflammatory alterations in the nucleus accumbens are corrected after risperidone treatment in a schizophrenia-related developmental model in rats
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  73. Jun 2021
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    OTULIN allies with LUBAC to govern angiogenesis by editing ALK1 linear polyubiquitin
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    Airway basal stem cells reutilize the embryonic proliferation regulator, Tgfβ-Id2 axis, for tissue regeneration
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  77. May 2021
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    Derivation of Intermediate Pluripotent Stem Cells Amenable to Primordial Germ Cell Specification
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    mTOR signaling regulates gastric epithelial progenitor homeostasis and gastric tumorigenesis via MEK1-ERKs and BMP-Smad1 pathways
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  81. Apr 2021
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    Obesity-Linked PPARγ S273 Phosphorylation Promotes Insulin Resistance through Growth Differentiation Factor 3
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      rabbit anti-phospho-Smad2 Ser465/467/ Smad3 Ser423/425

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    Cholesterol Pathway Inhibition Induces TGF-β Signaling to Promote Basal Differentiation in Pancreatic Cancer
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  84. Feb 2021
  85. elifesciences.org elifesciences.org
    Circulating transforming growth factor-β1 facilitates remyelination in the adult central nervous system
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  86. Dec 2020
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    Optogenetic investigation of BMP target gene expression diversity
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  88. Oct 2020
  89. academic.oup.com academic.oup.com
    An integrated genomic approach identifies HOXC8 as an upstream regulator in ovarian endometrioma
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    Repurposing mesalazine against cardiac fibrosis in vitro
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      Phospho-SMAD 2

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  91. Sep 2020
  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dullard-mediated Smad1/5/8 inhibition controls mouse cardiac neural crest cells condensation and outflow tract septation
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  93. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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      p‐Smad2/3

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    TGFβ signaling is required for tenocyte recruitment and functional neonatal tendon regeneration
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    Pbrm1 Steers Mesenchymal Stromal Cell Osteolineage Differentiation by Integrating PBAF-Dependent Chromatin Remodeling and BMP/TGF-β Signaling
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    Integration of Nodal and BMP Signaling by Mutual Signaling Effector Antagonism
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    Fibrodysplasia ossificans progressiva mutant ACVR1 signals by multiple modalities in the developing zebrafish
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    Axis Specification in Zebrafish Is Robust to Cell Mixing and Reveals a Regulation of Pattern Formation by Morphogenesis
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    KAP1 Is a Chromatin Reader that Couples Steps of RNA Polymerase II Transcription to Sustain Oncogenic Programs
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    Nodal and planar cell polarity signaling cooperate to regulate zebrafish convergence and extension gastrulation movements
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    LGR4, Not LGR5, Enhances hPSC Hematopoiesis by Facilitating Mesoderm Induction via TGF-Beta Signaling Activation
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    Activins as Dual Specificity TGF-β Family Molecules: SMAD-Activation via Activin- and BMP-Type 1 Receptors
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    Microphthalmia transcription factor expression contributes to bone marrow failure in Fanconi anemia
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      rabbit anti–phospho-SMAD2(S465/467)/SMAD3(S423/425)

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  105. Jan 2020
  106. www.sciencedirect.com www.sciencedirect.com
    Serum Amyloid A Proteins Induce Pathogenic Th17 Cells and Promote Inflammatory Disease
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    Dualism of FGF and TGF-β Signaling in Heterogeneous Cancer-Associated Fibroblast Activation with ETV1 as a Critical Determinant
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  108. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A counter gradient of Activin A and follistatin instructs the timing of hair cell differentiation in the murine cochlea
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    Smad7 Controls Immunoregulatory PDL2/1-PD1 Signaling in Intestinal Inflammation and Autoimmunity
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      DOI: 10.1016/j.celrep.2019.07.065

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    Macrophage MerTK Promotes Liver Fibrosis in Nonalcoholic Steatohepatitis
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    1. scibot 13 Jan 2020
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      DOI: 10.1016/j.cmet.2019.11.013

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      DOI: 10.1016/j.molcel.2019.04.021

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      DOI: 10.1016/j.chembiol.2019.03.009

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      RRID:AB_2631089

      DOI: 10.1016/j.immuni.2018.11.003

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  114. Nov 2018
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      RRID:AB_2631089

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    Macrophage-Associated PGK1 Phosphorylation Promotes Aerobic Glycolysis and Tumorigenesis
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    Long-Range Signaling Activation and Local Inhibition Separate the Mesoderm and Endoderm Lineages
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    A Brain-Region-Specific Neural Pathway Regulating Germinal Matrix Angiogenesis
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      Curator: @gabimpine

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    Follistatin Targets Distinct Pathways To Promote Brown Adipocyte Characteristics in Brown and White Adipose Tissues
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      AB_2631089

      Curator: @bandrow

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