39 Matching Annotations
  1. Apr 2024
  2. www.sciencedirect.com www.sciencedirect.com
    The MYCN 5′ UTR as a therapeutic target in neuroblastoma
    1
    1. scibot 25 Apr 2024
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    sciencedirect.com/science/article/pii/S2211124724004625
  3. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bisbiguanide analogs induce mitochondrial stress to inhibit lung cancer cell invasion
    1
    1. scibot 20 Apr 2024
      RRID:AB_2631166

      DOI: 10.1016/j.isci.2024.109591

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    ncbi.nlm.nih.gov/pmc/articles/PMC11022046/
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Plexin D1 emerges as a novel target in the development of neural lineage plasticity in treatment-resistant prostate cancer
    1
    1. scibot 18 Apr 2024
      RRID:AB_2631166

      DOI: 10.21203/rs.3.rs-4095949/v1

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    ncbi.nlm.nih.gov/pmc/articles/PMC10996809/
  5. Feb 2024
  6. 52.53.155.43 52.53.155.43
    YAP-mediated GPER signaling impedes proliferation and survival of prostate epithelium in benign prostatic hyperplasia
    1
    1. scibot 09 Feb 2024
      RRID:AB_2631166

      DOI: 10.1016/j.isci.2024.109125

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    52.53.155.43/3b983d9532a50e2ebeba730d1190ef88722ceb9a/PIIS2589004224003468-html.html
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Integrative modeling uncovers p21-driven drug resistance and prioritizes therapies for PIK3CA-mutant breast cancer
    1
    1. scibot 01 Feb 2024
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      DOI: 10.1038/s41698-024-00496-y

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    ncbi.nlm.nih.gov/pmc/articles/PMC10810864/
  8. Dec 2023
  9. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Transgelin Promotes Glioblastoma Stem Cell Hypoxic Responses and Maintenance Through p53 Acetylation
    1
    1. scibot 29 Dec 2023
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      DOI: 10.1002/advs.202305620

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    onlinelibrary.wiley.com/doi/10.1002/advs.202305620
  10. Nov 2023
  11. www.sciencedirect.com www.sciencedirect.com
    Pan-cancer tRNA-derived fragment CAT1 coordinates RBPMS to stabilize NOTCH2 mRNA to promote tumorigenesis
    1
    1. scibot 17 Nov 2023
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      DOI: 10.1016/j.celrep.2023.113408

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    sciencedirect.com/science/article/pii/S2211124723014201
  12. Jul 2023
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    Co-targeting RANK pathway treats and prevents acquired resistance to CDK4/6 inhibitors in luminal breast cancer
    1
    1. scibot 14 Jul 2023
      RRID:AB_2631166

      DOI: 10.1016/j.xcrm.2023.101120

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    sciencedirect.com/science/article/pii/S2666379123002483
  14. Jun 2023
  15. www.sciencedirect.com www.sciencedirect.com
    Mechanism underlying follicular hyperproliferation and oncogenesis in hidradenitis suppurativa
    1
    1. scibot 24 Jun 2023
      RRID:AB_2631166

      DOI: 10.1016/j.isci.2023.106896

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    sciencedirect.com/science/article/pii/S2589004223009732
  16. May 2023
  17. www.sciencedirect.com www.sciencedirect.com
    Modeling breast cancer proliferation, drug synergies, and alternating therapies
    1
    1. scibot 19 May 2023
      RRID:AB_2631166

      DOI: 10.1016/j.isci.2023.106714

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    sciencedirect.com/science/article/pii/S2589004223007915
  18. Feb 2023
  19. www.sciencedirect.com www.sciencedirect.com
    Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity
    1
    1. scibot 03 Feb 2023
      RRID:AB_2631166

      DOI: 10.1016/j.molcel.2023.01.015

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    sciencedirect.com/science/article/pii/S1097276523000382
  20. Aug 2022
  21. www.sciencedirect.com www.sciencedirect.com
    Analysis of neuroendocrine clones in NSCLCs using an immuno-guided laser-capture microdissection-based approach
    1
    1. scibot 23 Aug 2022
      RRID:AB_2631166

      DOI: 10.1016/j.crmeth.2022.100271

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    sciencedirect.com/science/article/pii/S2667237522001485
  22. www.sciencedirect.com www.sciencedirect.com
    Hypoxia-induced HMGB1 promotes glioma stem cells self-renewal and tumorigenicity via RAGE
    1
    1. scibot 16 Aug 2022
      RRID:AB_2631166

      DOI: 10.1016/j.isci.2022.104872

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    sciencedirect.com/science/article/pii/S2589004222011440
  23. Jul 2022
  24. www.sciencedirect.com www.sciencedirect.com
    A ROS-dependent mechanism promotes CDK2 phosphorylation to drive progression through S phase
    1
    1. scibot 12 Jul 2022
      RRID:AB_2631166

      DOI: 10.1016/j.devcel.2022.06.008

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    sciencedirect.com/science/article/pii/S1534580722004488
  25. Mar 2022
  26. www.nature.com www.nature.com
    Proteomic profiling reveals CDK6 upregulation as a targetable resistance mechanism for lenalidomide in multiple myeloma
    1
    1. scibot 05 Mar 2022
      RRID:AB_2631166

      DOI: 10.1038/s41467-022-28515-1

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    nature.com/articles/s41467-022-28515-1
  27. www.sciencedirect.com www.sciencedirect.com
    CDK/cyclin dependencies define extreme cancer cell-cycle heterogeneity and collateral vulnerabilities
    1
    1. scibot 02 Mar 2022
      RRID:AB_2631166

      DOI: 10.1016/j.celrep.2022.110448

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    sciencedirect.com/science/article/pii/S2211124722001759
  28. Dec 2021
  29. www.nature.com www.nature.com
    KDM6B promotes activation of the oncogenic CDK4/6-pRB-E2F pathway by maintaining enhancer activity in MYCN-amplified neuroblastoma
    1
    1. scibot 18 Dec 2021
      RRID:AB_2631166

      DOI: 10.1038/s41467-021-27502-2

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    nature.com/articles/s41467-021-27502-2
  30. Nov 2021
  31. www.sciencedirect.com www.sciencedirect.com
    RNA-binding protein FXR1 drives cMYC translation by recruiting eIF4F complex to the translation start site
    1
    1. scibot 03 Nov 2021
      RRID:AB_2631166

      DOI: 10.1016/j.celrep.2021.109934

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    sciencedirect.com/science/article/pii/S2211124721014078
  32. Sep 2021
  33. www.sciencedirect.com www.sciencedirect.com
    Rack1 is essential for corticogenesis by preventing p21-dependent senescence in neural stem cells
    1
    1. scibot 01 Sep 2021
      RRID:AB_2631166

      DOI: 10.1016/j.celrep.2021.109639

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    sciencedirect.com/science/article/pii/S2211124721010822
  34. www.sciencedirect.com www.sciencedirect.com
    Discovery of synthetic lethal and tumor suppressor paralog pairs in the human genome
    1
    1. scibot 01 Sep 2021
      RRID:AB_2631166

      DOI: 10.1016/j.celrep.2021.109597

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    sciencedirect.com/science/article/pii/S2211124721010354
  35. Aug 2021
  36. europepmc.org europepmc.org
    Untitled document
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    1. scibot 05 Aug 2021
      RRID:AB_2631166

      DOI: 10.7554/eLife.40856

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    europepmc.org/articles/PMC6292694/
  37. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 01 Aug 2021
      RRID:AB_2631166

      DOI: 10.1016/j.ccell.2018.11.006

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    sciencedirect.com/science/article/pii/S1535610818305270
  38. Jul 2021
  39. link.springer.com link.springer.com
    RASAL1 induces to downregulate the SCD1, leading to suppression of cell proliferation in colon cancer via LXRα/SREBP1c pathway
    1
    1. scibot 31 Jul 2021
      CDK4

      DOI: 10.1186/s40659-019-0268-x

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    link.springer.com/article/10.1186/s40659-019-0268-x
  40. www.sciencedirect.com www.sciencedirect.com
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    1. scibot 30 Jul 2021
      RRID:AB_2631166

      DOI: 10.1016/j.chembiol.2018.11.006

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    sciencedirect.com/science/article/pii/S2451945618304136
  41. May 2021
  42. www.sciencedirect.com www.sciencedirect.com
    Cell size homeostasis is maintained by CDK4-dependent activation of p38 MAPK
    1
    1. scibot 22 May 2021
      RRID:AB_2631166

      DOI: 10.1016/j.devcel.2021.04.030

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    sciencedirect.com/science/article/pii/S1534580721003993
  43. www.sciencedirect.com www.sciencedirect.com
    Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer
    1
    1. scibot 07 May 2021
      RRID:AB_2631166

      DOI: 10.1016/j.molcel.2020.04.027

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    sciencedirect.com/science/article/pii/S1097276520302690
  44. Apr 2021
  45. www.sciencedirect.com www.sciencedirect.com
    Dual targeting of the epigenome via FACT complex and histone deacetylase is a potent treatment strategy for DIPG
    1
    1. scibot 14 Apr 2021
      RRID:AB_2631166

      DOI: 10.1016/j.celrep.2021.108994

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    sciencedirect.com/science/article/pii/S2211124721003089
  46. Jan 2021
  47. link.springer.com link.springer.com
    A novel ligand of the translationally controlled tumor protein (TCTP) identified by virtual drug screening for cancer differentiation therapy
    1
    1. scibot 28 Jan 2021
      RRID:AB_2631166

      DOI: 10.1007/s10637-020-01042-w

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    link.springer.com/article/10.1007/s10637-020-01042-w
  48. Nov 2020
  49. link.springer.com link.springer.com
    p75NTR Promotes Astrocyte Proliferation in Response to Cortical Stab Wound
    1
    1. scibot 25 Nov 2020
      anti-CDK4

      DOI: 10.1007/s10571-020-01006-x

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    link.springer.com/article/10.1007/s10571-020-01006-x
  50. Sep 2020
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Three-dimensional growth of breast cancer cells potentiates the anti-tumor effects of unacylated ghrelin and AZP-531
    1
    1. scibot 07 Sep 2020
      RRID:AB_2631166

      DOI: 10.7554/eLife.56913

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    ncbi.nlm.nih.gov/pmc/articles/PMC7363447/
  52. onlinelibrary.wiley.com onlinelibrary.wiley.com
    KIF15 promotes the evolution of gastric cancer cells through inhibition of reactive oxygen species‐mediated apoptosis
    1
    1. scibot 06 Sep 2020
      RRID:AB_2631166

      DOI: 10.1002/jcp.29743

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    onlinelibrary.wiley.com/doi/10.1002/jcp.29743
  53. www.sciencedirect.com www.sciencedirect.com
    Cyclin N-Terminal Domain-Containing-1 Coordinates Meiotic Crossover Formation with Cell-Cycle Progression in a Cyclin-Independent Manner
    1
    1. scibot 04 Sep 2020
      RRID:AB_2631166

      DOI: 10.1016/j.celrep.2020.107858

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    sciencedirect.com/science/article/pii/S2211124720308391
  54. Jan 2020
  55. www.sciencedirect.com www.sciencedirect.com
    MicroRNA-Mediated Suppression of the TGF-β Pathway Confers Transmissible and Reversible CDK4/6 Inhibitor Resistance
    1
    1. scibot 13 Jan 2020
      RRID:AB_2631166

      DOI: 10.1016/j.celrep.2019.02.023

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    sciencedirect.com/science/article/pii/S2211124719301937
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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      RRID:AB_2631166

      DOI: 10.7554/eLife.40856

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    ncbi.nlm.nih.gov/pmc/articles/PMC6292694/
  57. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 13 Jan 2020
      RRID:AB_2631166

      DOI: 10.1016/j.chembiol.2019.03.012

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    sciencedirect.com/science/article/pii/S2451945619301084
  58. Nov 2018
  59. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Testosterone regulates myosin II isoforms expression and functional activity in the rat prostate
    1
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      AB_2631166

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    onlinelibrary.wiley.com/doi/full/10.1002/pros.23702
  60. www.sciencedirect.com www.sciencedirect.com
    Mutant p53 Gains Its Function via c-Myc Activation upon CDK4 Phosphorylation at Serine 249 and Consequent PIN1 Binding
    1
    1. scibot 05 Nov 2018
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    sciencedirect.com/science/article/pii/S1097276517308419
  61. www.sciencedirect.com www.sciencedirect.com
    Lessons in PROTAC Design from Selective Degradation with a Promiscuous Warhead
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    1. scibot 05 Nov 2018
      RRID:AB_2631166

      Curator: @evieth

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    sciencedirect.com/science/article/pii/S2451945617303549
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Chemoproteomic Approach to Query the Degradable Kinome Using a Multi-kinase Degrader
    1
    1. scibot 05 Nov 2018
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    ncbi.nlm.nih.gov/pmc/articles/PMC6427047/