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  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    p21 regulates expression of ECM components and promotes pulmonary fibrosis via CDK4 and Rb
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  3. Sep 2024
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    Sex-dependent effects in the aged melanoma tumor microenvironment influence invasion and resistance to targeted therapy
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  5. Jul 2024
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    A Kinome-Wide Synthetic Lethal CRISPR/Cas9 Screen Reveals That mTOR Inhibition Prevents Adaptive Resistance to CDK4/CDK6 Blockade in HNSCC
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  7. Jun 2024
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    Plexin D1 emerges as a novel target in the development of neural lineage plasticity in treatment-resistant prostate cancer
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  9. Apr 2024
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    The MYCN 5′ UTR as a therapeutic target in neuroblastoma
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    Bisbiguanide analogs induce mitochondrial stress to inhibit lung cancer cell invasion
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    Plexin D1 emerges as a novel target in the development of neural lineage plasticity in treatment-resistant prostate cancer
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    1. scibot 18 Apr 2024
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      DOI: 10.21203/rs.3.rs-4095949/v1

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  13. Feb 2024
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    YAP-mediated GPER signaling impedes proliferation and survival of prostate epithelium in benign prostatic hyperplasia
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    Integrative modeling uncovers p21-driven drug resistance and prioritizes therapies for PIK3CA-mutant breast cancer
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  16. Dec 2023
  17. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Transgelin Promotes Glioblastoma Stem Cell Hypoxic Responses and Maintenance Through p53 Acetylation
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    1. scibot 29 Dec 2023
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      DOI: 10.1002/advs.202305620

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  18. Nov 2023
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    Pan-cancer tRNA-derived fragment CAT1 coordinates RBPMS to stabilize NOTCH2 mRNA to promote tumorigenesis
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    sciencedirect.com/science/article/pii/S2211124723014201
  20. Jul 2023
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    Co-targeting RANK pathway treats and prevents acquired resistance to CDK4/6 inhibitors in luminal breast cancer
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    1. scibot 14 Jul 2023
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      DOI: 10.1016/j.xcrm.2023.101120

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    sciencedirect.com/science/article/pii/S2666379123002483
  22. Jun 2023
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    Mechanism underlying follicular hyperproliferation and oncogenesis in hidradenitis suppurativa
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    sciencedirect.com/science/article/pii/S2589004223009732
  24. May 2023
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    Modeling breast cancer proliferation, drug synergies, and alternating therapies
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    sciencedirect.com/science/article/pii/S2589004223007915
  26. Feb 2023
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    Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity
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  28. Aug 2022
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    Analysis of neuroendocrine clones in NSCLCs using an immuno-guided laser-capture microdissection-based approach
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    sciencedirect.com/science/article/pii/S2667237522001485
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    Hypoxia-induced HMGB1 promotes glioma stem cells self-renewal and tumorigenicity via RAGE
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  31. Jul 2022
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    A ROS-dependent mechanism promotes CDK2 phosphorylation to drive progression through S phase
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    sciencedirect.com/science/article/pii/S1534580722004488
  33. Mar 2022
  34. www.nature.com www.nature.com
    Proteomic profiling reveals CDK6 upregulation as a targetable resistance mechanism for lenalidomide in multiple myeloma
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      DOI: 10.1038/s41467-022-28515-1

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    CDK/cyclin dependencies define extreme cancer cell-cycle heterogeneity and collateral vulnerabilities
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    sciencedirect.com/science/article/pii/S2211124722001759
  36. Dec 2021
  37. www.nature.com www.nature.com
    KDM6B promotes activation of the oncogenic CDK4/6-pRB-E2F pathway by maintaining enhancer activity in MYCN-amplified neuroblastoma
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      DOI: 10.1038/s41467-021-27502-2

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  38. Nov 2021
  39. www.sciencedirect.com www.sciencedirect.com
    RNA-binding protein FXR1 drives cMYC translation by recruiting eIF4F complex to the translation start site
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    sciencedirect.com/science/article/pii/S2211124721014078
  40. Sep 2021
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    Rack1 is essential for corticogenesis by preventing p21-dependent senescence in neural stem cells
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      DOI: 10.1016/j.celrep.2021.109639

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    sciencedirect.com/science/article/pii/S2211124721010822
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    Discovery of synthetic lethal and tumor suppressor paralog pairs in the human genome
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    sciencedirect.com/science/article/pii/S2211124721010354
  43. Aug 2021
  44. europepmc.org europepmc.org
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      DOI: 10.7554/eLife.40856

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      DOI: 10.1016/j.ccell.2018.11.006

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  46. Jul 2021
  47. link.springer.com link.springer.com
    RASAL1 induces to downregulate the SCD1, leading to suppression of cell proliferation in colon cancer via LXRα/SREBP1c pathway
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    1. scibot 31 Jul 2021
      CDK4

      DOI: 10.1186/s40659-019-0268-x

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  48. www.sciencedirect.com www.sciencedirect.com
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      DOI: 10.1016/j.chembiol.2018.11.006

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    sciencedirect.com/science/article/pii/S2451945618304136
  49. May 2021
  50. www.sciencedirect.com www.sciencedirect.com
    Cell size homeostasis is maintained by CDK4-dependent activation of p38 MAPK
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    sciencedirect.com/science/article/pii/S1534580721003993
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    Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer
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      DOI: 10.1016/j.molcel.2020.04.027

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    sciencedirect.com/science/article/pii/S1097276520302690
  52. Apr 2021
  53. www.sciencedirect.com www.sciencedirect.com
    Dual targeting of the epigenome via FACT complex and histone deacetylase is a potent treatment strategy for DIPG
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      DOI: 10.1016/j.celrep.2021.108994

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    sciencedirect.com/science/article/pii/S2211124721003089
  54. Jan 2021
  55. link.springer.com link.springer.com
    A novel ligand of the translationally controlled tumor protein (TCTP) identified by virtual drug screening for cancer differentiation therapy
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      DOI: 10.1007/s10637-020-01042-w

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    link.springer.com/article/10.1007/s10637-020-01042-w
  56. Nov 2020
  57. link.springer.com link.springer.com
    p75NTR Promotes Astrocyte Proliferation in Response to Cortical Stab Wound
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      anti-CDK4

      DOI: 10.1007/s10571-020-01006-x

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    link.springer.com/article/10.1007/s10571-020-01006-x
  58. Sep 2020
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Three-dimensional growth of breast cancer cells potentiates the anti-tumor effects of unacylated ghrelin and AZP-531
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      DOI: 10.7554/eLife.56913

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    ncbi.nlm.nih.gov/pmc/articles/PMC7363447/
  60. onlinelibrary.wiley.com onlinelibrary.wiley.com
    KIF15 promotes the evolution of gastric cancer cells through inhibition of reactive oxygen species‐mediated apoptosis
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      DOI: 10.1002/jcp.29743

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    onlinelibrary.wiley.com/doi/10.1002/jcp.29743
  61. www.sciencedirect.com www.sciencedirect.com
    Cyclin N-Terminal Domain-Containing-1 Coordinates Meiotic Crossover Formation with Cell-Cycle Progression in a Cyclin-Independent Manner
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      RRID:AB_2631166

      DOI: 10.1016/j.celrep.2020.107858

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    sciencedirect.com/science/article/pii/S2211124720308391
  62. Jan 2020
  63. www.sciencedirect.com www.sciencedirect.com
    MicroRNA-Mediated Suppression of the TGF-β Pathway Confers Transmissible and Reversible CDK4/6 Inhibitor Resistance
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    1. scibot 13 Jan 2020
      RRID:AB_2631166

      DOI: 10.1016/j.celrep.2019.02.023

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  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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      DOI: 10.7554/eLife.40856

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      RRID:AB_2631166

      DOI: 10.1016/j.chembiol.2019.03.012

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    sciencedirect.com/science/article/pii/S2451945619301084
  66. Nov 2018
  67. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Testosterone regulates myosin II isoforms expression and functional activity in the rat prostate
    1
    1. scibot 05 Nov 2018
      AB_2631166

      Curator: @anp055

      Resource used:

      (Cell Signaling Technology Cat# 12790, RRID:AB_2631166)

      SciCrunch record: RRID:AB_2631166

      Alternate resolvers: SciCrunch xml N2T identifiers.org

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      RRID:AB_2631166 RRIDCUR:Validated
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    onlinelibrary.wiley.com/doi/full/10.1002/pros.23702
  68. www.sciencedirect.com www.sciencedirect.com
    Mutant p53 Gains Its Function via c-Myc Activation upon CDK4 Phosphorylation at Serine 249 and Consequent PIN1 Binding
    1
    1. scibot 05 Nov 2018
      RRID:AB_2631166

      Resource used:

      (Cell Signaling Technology Cat# 12790, RRID:AB_2631166)

      SciCrunch record: RRID:AB_2631166

      Alternate resolvers: SciCrunch xml N2T identifiers.org

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      RRID:AB_2631166
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    sciencedirect.com/science/article/pii/S1097276517308419
  69. www.sciencedirect.com www.sciencedirect.com
    Lessons in PROTAC Design from Selective Degradation with a Promiscuous Warhead
    1
    1. scibot 05 Nov 2018
      RRID:AB_2631166

      Curator: @evieth

      Resource used:

      (Cell Signaling Technology Cat# 12790, RRID:AB_2631166)

      SciCrunch record: RRID:AB_2631166

      Alternate resolvers: SciCrunch xml N2T identifiers.org

      What is this?

      RRID:AB_2631166 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S2451945617303549
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Chemoproteomic Approach to Query the Degradable Kinome Using a Multi-kinase Degrader
    1
    1. scibot 05 Nov 2018
      RRID:AB_2631166

      Resource used:

      (Cell Signaling Technology Cat# 12790, RRID:AB_2631166)

      SciCrunch record: RRID:AB_2631166

      Alternate resolvers: SciCrunch xml N2T identifiers.org

      What is this?

      RRID:AB_2631166
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    ncbi.nlm.nih.gov/pmc/articles/PMC6427047/