Hypothesis

63 Matching Annotations

Last 7 days
www.sciencedirect.com www.sciencedirect.com

PRDM16 modulates aspects of cell cycle dynamics and maturation in human iPSC-derived cardiomyocytes

1
1. scibot 11 Jul 2026
  
  in Public
  
  RRID:AB_2631166
  
  DOI: 10.1016/j.stemcr.2026.103005
  
  Resource: (Cell Signaling Technology Cat# 12790, RRID:AB_2631166)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2631166
  
  What is this?
  
  RRID:AB_2631166
Visit annotations in context

Tags

RRID:AB_2631166

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S221367112600216X
Jun 2026
www.sciencedirect.com www.sciencedirect.com

Distinct ERK and PI3K dependencies mediate a heterogeneous response to RAS(ON) inhibition in KRAS-mutant colorectal cancer

1
1. scibot 22 Jun 2026
  
  in Public
  
  RRID:AB_2631166
  
  DOI: 10.1016/j.celrep.2026.117559
  
  Resource: (Cell Signaling Technology Cat# 12790, RRID:AB_2631166)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2631166
  
  What is this?
  
  RRID:AB_2631166
Visit annotations in context

Tags

RRID:AB_2631166

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124726006376
www.nature.com www.nature.com

Increased vulnerability of colorectal cancer models with high alkylation damage to NTHL1 inactivation

1
1. scibot 18 Jun 2026
  
  in Public
  
  RRID:AB_2631166
  
  DOI: 10.1038/s41598-026-46639-y
  
  Resource: (Cell Signaling Technology Cat# 12790, RRID:AB_2631166)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2631166
  
  What is this?
  
  RRID:AB_2631166
Visit annotations in context

Tags

RRID:AB_2631166

Annotators

scibot

URL

nature.com/articles/s41598-026-46639-y
May 2026
link.springer.com link.springer.com

Celecoxib potentiates ribociclib-induced apoptosis and anti-tumor activity by co-targeting COX-2/NF-κB and PI3K/AKT/mTOR pathways in hormone receptor-positive/HER2-negative breast cancer

1
1. scibot 08 May 2026
  
  in Public
  
  RRID:AB_2631166
  
  DOI: 10.1007/s10495-026-02340-z
  
  Resource: (Cell Signaling Technology Cat# 12790, RRID:AB_2631166)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2631166
  
  What is this?
  
  RRID:AB_2631166
Visit annotations in context

Tags

RRID:AB_2631166

Annotators

scibot

URL

link.springer.com/article/10.1007/s10495-026-02340-z
Feb 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Aberrant CDK4/6-driven cell-cycle reentry drives neuronal loss and defines a therapeutic target in C9orf72 ALS/FTD

1
1. scibot 04 Feb 2026
  
  in Public
  
  RRID:AB_2631166
  
  DOI: 10.1016/j.isci.2025.114596
  
  Resource: (Cell Signaling Technology Cat# 12790, RRID:AB_2631166)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2631166
  
  What is this?
  
  RRID:AB_2631166
Visit annotations in context

Tags

RRID:AB_2631166

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12856326/
Dec 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Anti-Cancer Effects of the Ethyl Acetate Fraction From Opuntia humifusa on Human Triple-Negative Breast Cancer Cells

1
1. scibot 18 Dec 2025
  
  in Public
  
  RRID: AB_2631166
  
  DOI: 10.1177/15347354251401187
  
  Resource: (Cell Signaling Technology Cat# 12790, RRID:AB_2631166)
  
  Curator: @evieth
  
  SciCrunch record: RRID:AB_2631166
  
  What is this?
  
  RRID:AB_2631166
Visit annotations in context

Tags

RRID:AB_2631166

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12705953/
www.nature.com www.nature.com

CDK2 inhibition enhances CDK4/6 inhibitor antitumor activity in comprehensive breast cancer PDX model screen

2
1. scibot 06 Dec 2025
  
  in Public
  
  RRID:AB_2631166
  
  DOI: 10.1038/s41523-025-00851-7
  
  Resource: (Cell Signaling Technology Cat# 12790, RRID:AB_2631166)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2631166
  
  What is this?
  
  RRID:AB_2631166
2. scibot 06 Dec 2025
  
  in Public
  
  RRID:AB_2631166
  
  DOI: 10.1038/s41523-025-00851-7
  
  Resource: (Cell Signaling Technology Cat# 12790, RRID:AB_2631166)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2631166
  
  What is this?
  
  RRID:AB_2631166
Visit annotations in context

Tags

RRID:AB_2631166

Annotators

scibot

URL

nature.com/articles/s41523-025-00851-7
Nov 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

YAP/TAZ transcriptional co-activators create therapeutic vulnerability to verteporfin in EGFR mutant glioblastoma

1
1. scibot 08 Nov 2025
  
  in Public
  
  AB_2631166
  
  DOI: 10.1158/1078-0432.CCR-20-0018
  
  Resource: (Cell Signaling Technology Cat# 12790, RRID:AB_2631166)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2631166
  
  What is this?
  
  RRID:AB_2631166
Visit annotations in context

Tags

RRID:AB_2631166

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC8440125/
Oct 2025
www.biorxiv.org www.biorxiv.org

CDK4/6 Inhibition Reverses MEIS2 Suppression of CRL4CRBN to Enhance Immunomodulatory Drug Therapy in Multiple Myeloma

1
1. scibot 21 Oct 2025
  
  in Public
  
  RRID:AB_2631166
  
  DOI: 10.1101/2025.10.14.681840
  
  Resource: (Cell Signaling Technology Cat# 12790, RRID:AB_2631166)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2631166
  
  What is this?
  
  RRID:AB_2631166
Visit annotations in context

Tags

RRID:AB_2631166

Annotators

scibot

URL

biorxiv.org/content/10.1101/2025.10.14.681840v1
Aug 2025
www.sciencedirect.com www.sciencedirect.com

Design of multi-target peptide modulators for protein chaperone networks

1
1. scibot 26 Aug 2025
  
  in Public
  
  RRID:AB_2631166
  
  DOI: 10.1016/j.str.2025.07.021
  
  Resource: (Cell Signaling Technology Cat# 12790, RRID:AB_2631166)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2631166
  
  What is this?
  
  RRID:AB_2631166
Visit annotations in context

Tags

RRID:AB_2631166

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0969212625002692
www.sciencedirect.com www.sciencedirect.com

A redox switch in p21-CDK feedback during G2 phase controls the proliferation-cell cycle exit decision

1
1. scibot 26 Aug 2025
  
  in Public
  
  RRID:AB_2631166
  
  DOI: 10.1016/j.molcel.2025.07.023
  
  Resource: (Cell Signaling Technology Cat# 12790, RRID:AB_2631166)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2631166
  
  What is this?
  
  RRID:AB_2631166
Visit annotations in context

Tags

RRID:AB_2631166

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S109727652500646X
52.53.155.43 52.53.155.43

1-s2.0-S2589004225015652-main-html.html

1
1. scibot 07 Aug 2025
  
  in Public
  
  AB_2631166
  
  DOI: 10.1016/j.isci.2025.113304
  
  Resource: (Cell Signaling Technology Cat# 12790, RRID:AB_2631166)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2631166
  
  What is this?
  
  RRID:AB_2631166
Visit annotations in context

Tags

RRID:AB_2631166

Annotators

scibot

URL

52.53.155.43/85cee3d161a0de2e88ed1ed9d4903a9813261aae/1-s2.0-S2589004225015652-main-html.html
May 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

CDK4 loss-of-function mutations cause microcephaly and short stature

1
1. scibot 20 May 2025
  
  in Public
  
  RRID:AB_2631166
  
  DOI: 10.1101/gad.352311.124
  
  Resource: (Cell Signaling Technology Cat# 12790, RRID:AB_2631166)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2631166
  
  What is this?
  
  RRID:AB_2631166
Visit annotations in context

Tags

RRID:AB_2631166

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC7617628/
Apr 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Profiling the Activity of the Potent and Highly Selective CDK2 Inhibitor BLU-222 Reveals Determinants of Response in CCNE1-Aberrant Ovarian and Endometrial Tumors

1
1. scibot 05 Apr 2025
  
  in Public
  
  AB_2631166
  
  DOI: 10.1158/0008-5472.CAN-24-2360
  
  Resource: (Cell Signaling Technology Cat# 12790, RRID:AB_2631166)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2631166
  
  What is this?
  
  RRID:AB_2631166
Visit annotations in context

Tags

RRID:AB_2631166

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC11967718/
Mar 2025
www.sciencedirect.com www.sciencedirect.com

CDK4 selective inhibition improves preclinical anti-tumor efficacy and safety

1
1. scibot 11 Mar 2025
  
  in Public
  
  RRID:AB_2631166
  
  DOI: 10.1016/j.ccell.2025.02.006
  
  Resource: (Cell Signaling Technology Cat# 12790, RRID:AB_2631166)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2631166
  
  What is this?
  
  RRID:AB_2631166
Visit annotations in context

Tags

RRID:AB_2631166

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1535610825000583
Feb 2025
www.sciencedirect.com www.sciencedirect.com

Biguanides antithetically regulate tumor properties by the dose-dependent mitochondrial reprogramming-driven c-Src pathway

1
1. scibot 11 Feb 2025
  
  in Public
  
  RRID:AB_2631166
  
  DOI: 10.1016/j.xcrm.2025.101941
  
  Resource: (Cell Signaling Technology Cat# 12790, RRID:AB_2631166)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2631166
  
  What is this?
  
  RRID:AB_2631166
Visit annotations in context

Tags

RRID:AB_2631166

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S266637912500014X
Jan 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

CDKN2A/B homozygous deletion sensitizes IDH-mutant glioma to CDK4/6 inhibition

1
1. scibot 25 Jan 2025
  
  in Public
  
  RRID:AB_2631166
  
  DOI: 10.1158/1078-0432.CCR-24-0562
  
  Resource: (Cell Signaling Technology Cat# 12790, RRID:AB_2631166)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2631166
  
  What is this?
  
  RRID:AB_2631166
Visit annotations in context

Tags

RRID:AB_2631166

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC11250907/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

ASPSCR1::TFE3 Drives Alveolar Soft Part Sarcoma by Inducing Targetable Transcriptional Programs

1
1. scibot 25 Jan 2025
  
  in Public
  
  RRID:AB_2631166
  
  DOI: 10.1158/0008-5472.CAN-23-2115
  
  Resource: (Cell Signaling Technology Cat# 12790, RRID:AB_2631166)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2631166
  
  What is this?
  
  RRID:AB_2631166
Visit annotations in context

Tags

RRID:AB_2631166

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC11250573/
Dec 2024
52.53.155.43 52.53.155.43

1-s2.0-S2589004224027329-main-html.html

1
1. scibot 06 Dec 2024
  
  in Public
  
  RRID:AB_2631166
  
  DOI: 10.1016/j.isci.2024.111505
  
  Resource: (Cell Signaling Technology Cat# 12790, RRID:AB_2631166)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2631166
  
  What is this?
  
  RRID:AB_2631166
Visit annotations in context

Tags

RRID:AB_2631166

Annotators

scibot

URL

52.53.155.43/3c53ef10f625befcd704a131cd24200ff9587189/1-s2.0-S2589004224027329-main-html.html
Nov 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

p21 regulates expression of ECM components and promotes pulmonary fibrosis via CDK4 and Rb

1
1. scibot 21 Nov 2024
  
  in Public
  
  RRID:AB_2631166
  
  DOI: 10.1038/s44318-024-00246-7
  
  Resource: (Cell Signaling Technology Cat# 12790, RRID:AB_2631166)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2631166
  
  What is this?
  
  RRID:AB_2631166
Visit annotations in context

Tags

RRID:AB_2631166

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC11574164/
Sep 2024
www.sciencedirect.com www.sciencedirect.com

Sex-dependent effects in the aged melanoma tumor microenvironment influence invasion and resistance to targeted therapy

1
1. scibot 10 Sep 2024
  
  in Public
  
  AB_2631166
  
  DOI: 10.1016/j.cell.2024.08.013
  
  Resource: (Cell Signaling Technology Cat# 12790, RRID:AB_2631166)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2631166
  
  What is this?
  
  RRID:AB_2631166
Visit annotations in context

Tags

RRID:AB_2631166

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0092867424009048
Jul 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A Kinome-Wide Synthetic Lethal CRISPR/Cas9 Screen Reveals That mTOR Inhibition Prevents Adaptive Resistance to CDK4/CDK6 Blockade in HNSCC

1
1. scibot 31 Jul 2024
  
  in Public
  
  RRID:AB_2631166
  
  DOI: 10.1158/2767-9764.CRC-24-0247
  
  Resource: AB_2631166
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2631166
  
  What is this?
  
  RRID:AB_2631166
Visit annotations in context

Tags

RRID:AB_2631166

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC11284272/
Jun 2024
link.springer.com link.springer.com

Plexin D1 emerges as a novel target in the development of neural lineage plasticity in treatment-resistant prostate cancer

1
1. scibot 28 Jun 2024
  
  in Public
  
  RRID:AB_2631166
  
  DOI: 10.1038/s41388-024-03081-6
  
  Resource: (Cell Signaling Technology Cat# 12790, RRID:AB_2631166)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2631166
  
  What is this?
  
  RRID:AB_2631166
Visit annotations in context

Tags

RRID:AB_2631166

Annotators

scibot

URL

link.springer.com/article/10.1038/s41388-024-03081-6
Apr 2024
www.sciencedirect.com www.sciencedirect.com

The MYCN 5′ UTR as a therapeutic target in neuroblastoma

1
1. scibot 25 Apr 2024
  
  in Public
  
  RRID:AB_2631166
  
  DOI: 10.1016/j.celrep.2024.114134
  
  Resource: (Cell Signaling Technology Cat# 12790, RRID:AB_2631166)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2631166
  
  What is this?
  
  RRID:AB_2631166
Visit annotations in context

Tags

RRID:AB_2631166

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124724004625
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Bisbiguanide analogs induce mitochondrial stress to inhibit lung cancer cell invasion

1
1. scibot 20 Apr 2024
  
  in Public
  
  RRID:AB_2631166
  
  DOI: 10.1016/j.isci.2024.109591
  
  Resource: (Cell Signaling Technology Cat# 12790, RRID:AB_2631166)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2631166
  
  What is this?
  
  RRID:AB_2631166
Visit annotations in context

Tags

RRID:AB_2631166

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC11022046/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Plexin D1 emerges as a novel target in the development of neural lineage plasticity in treatment-resistant prostate cancer

1
1. scibot 18 Apr 2024
  
  in Public
  
  RRID:AB_2631166
  
  DOI: 10.21203/rs.3.rs-4095949/v1
  
  Resource: (Cell Signaling Technology Cat# 12790, RRID:AB_2631166)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2631166
  
  What is this?
  
  RRID:AB_2631166
Visit annotations in context

Tags

RRID:AB_2631166

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10996809/
Feb 2024
52.53.155.43 52.53.155.43

YAP-mediated GPER signaling impedes proliferation and survival of prostate epithelium in benign prostatic hyperplasia

1
1. scibot 09 Feb 2024
  
  in Public
  
  RRID:AB_2631166
  
  DOI: 10.1016/j.isci.2024.109125
  
  Resource: (Cell Signaling Technology Cat# 12790, RRID:AB_2631166)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2631166
  
  What is this?
  
  RRID:AB_2631166
Visit annotations in context

Tags

RRID:AB_2631166

Annotators

scibot

URL

52.53.155.43/3b983d9532a50e2ebeba730d1190ef88722ceb9a/PIIS2589004224003468-html.html
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Integrative modeling uncovers p21-driven drug resistance and prioritizes therapies for PIK3CA-mutant breast cancer

1
1. scibot 01 Feb 2024
  
  in Public
  
  RRID:AB_2631166
  
  DOI: 10.1038/s41698-024-00496-y
  
  Resource: (Cell Signaling Technology Cat# 12790, RRID:AB_2631166)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2631166
  
  What is this?
  
  RRID:AB_2631166
Visit annotations in context

Tags

RRID:AB_2631166

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10810864/
Dec 2023
onlinelibrary.wiley.com onlinelibrary.wiley.com

Transgelin Promotes Glioblastoma Stem Cell Hypoxic Responses and Maintenance Through p53 Acetylation

1
1. scibot 29 Dec 2023
  
  in Public
  
  RRID:AB_2631166
  
  DOI: 10.1002/advs.202305620
  
  Resource: (Cell Signaling Technology Cat# 12790, RRID:AB_2631166)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2631166
  
  What is this?
  
  RRID:AB_2631166
Visit annotations in context

Tags

RRID:AB_2631166

Annotators

scibot

URL

onlinelibrary.wiley.com/doi/10.1002/advs.202305620
Nov 2023
www.sciencedirect.com www.sciencedirect.com

Pan-cancer tRNA-derived fragment CAT1 coordinates RBPMS to stabilize NOTCH2 mRNA to promote tumorigenesis

1
1. scibot 17 Nov 2023
  
  in Public
  
  RRID:AB_2631166
  
  DOI: 10.1016/j.celrep.2023.113408
  
  Resource: (Cell Signaling Technology Cat# 12790, RRID:AB_2631166)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2631166
  
  What is this?
  
  RRID:AB_2631166
Visit annotations in context

Tags

RRID:AB_2631166

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124723014201
Jul 2023
www.sciencedirect.com www.sciencedirect.com

Co-targeting RANK pathway treats and prevents acquired resistance to CDK4/6 inhibitors in luminal breast cancer

1
1. scibot 14 Jul 2023
  
  in Public
  
  RRID:AB_2631166
  
  DOI: 10.1016/j.xcrm.2023.101120
  
  Resource: (Cell Signaling Technology Cat# 12790, RRID:AB_2631166)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2631166
  
  What is this?
  
  RRID:AB_2631166
Visit annotations in context

Tags

RRID:AB_2631166

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2666379123002483
Jun 2023
www.sciencedirect.com www.sciencedirect.com

Mechanism underlying follicular hyperproliferation and oncogenesis in hidradenitis suppurativa

1
1. scibot 24 Jun 2023
  
  in Public
  
  RRID:AB_2631166
  
  DOI: 10.1016/j.isci.2023.106896
  
  Resource: (Cell Signaling Technology Cat# 12790, RRID:AB_2631166)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2631166
  
  What is this?
  
  RRID:AB_2631166
Visit annotations in context

Tags

RRID:AB_2631166

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2589004223009732
May 2023
www.sciencedirect.com www.sciencedirect.com

Modeling breast cancer proliferation, drug synergies, and alternating therapies

1
1. scibot 19 May 2023
  
  in Public
  
  RRID:AB_2631166
  
  DOI: 10.1016/j.isci.2023.106714
  
  Resource: (Cell Signaling Technology Cat# 12790, RRID:AB_2631166)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2631166
  
  What is this?
  
  RRID:AB_2631166
Visit annotations in context

Tags

RRID:AB_2631166

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2589004223007915
Feb 2023
www.sciencedirect.com www.sciencedirect.com

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity

1
1. scibot 03 Feb 2023
  
  in Public
  
  RRID:AB_2631166
  
  DOI: 10.1016/j.molcel.2023.01.015
  
  Resource: (Cell Signaling Technology Cat# 12790, RRID:AB_2631166)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2631166
  
  What is this?
  
  RRID:AB_2631166
Visit annotations in context

Tags

RRID:AB_2631166

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1097276523000382
Aug 2022
www.sciencedirect.com www.sciencedirect.com

Analysis of neuroendocrine clones in NSCLCs using an immuno-guided laser-capture microdissection-based approach

1
1. scibot 23 Aug 2022
  
  in Public
  
  RRID:AB_2631166
  
  DOI: 10.1016/j.crmeth.2022.100271
  
  Resource: (Cell Signaling Technology Cat# 12790, RRID:AB_2631166)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2631166
  
  What is this?
  
  RRID:AB_2631166
Visit annotations in context

Tags

RRID:AB_2631166

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2667237522001485
www.sciencedirect.com www.sciencedirect.com

Hypoxia-induced HMGB1 promotes glioma stem cells self-renewal and tumorigenicity via RAGE

1
1. scibot 16 Aug 2022
  
  in Public
  
  RRID:AB_2631166
  
  DOI: 10.1016/j.isci.2022.104872
  
  Resource: (Cell Signaling Technology Cat# 12790, RRID:AB_2631166)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2631166
  
  What is this?
  
  RRID:AB_2631166
Visit annotations in context

Tags

RRID:AB_2631166

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2589004222011440
Jul 2022
www.sciencedirect.com www.sciencedirect.com

A ROS-dependent mechanism promotes CDK2 phosphorylation to drive progression through S phase

1
1. scibot 12 Jul 2022
  
  in Public
  
  RRID:AB_2631166
  
  DOI: 10.1016/j.devcel.2022.06.008
  
  Resource: (Cell Signaling Technology Cat# 12790, RRID:AB_2631166)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2631166
  
  What is this?
  
  RRID:AB_2631166
Visit annotations in context

Tags

RRID:AB_2631166

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1534580722004488
Mar 2022
www.nature.com www.nature.com

Proteomic profiling reveals CDK6 upregulation as a targetable resistance mechanism for lenalidomide in multiple myeloma

1
1. scibot 05 Mar 2022
  
  in Public
  
  RRID:AB_2631166
  
  DOI: 10.1038/s41467-022-28515-1
  
  Resource: (Cell Signaling Technology Cat# 12790, RRID:AB_2631166)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2631166
  
  What is this?
  
  RRID:AB_2631166
Visit annotations in context

Tags

RRID:AB_2631166

Annotators

scibot

URL

nature.com/articles/s41467-022-28515-1
www.sciencedirect.com www.sciencedirect.com

CDK/cyclin dependencies define extreme cancer cell-cycle heterogeneity and collateral vulnerabilities

1
1. scibot 02 Mar 2022
  
  in Public
  
  RRID:AB_2631166
  
  DOI: 10.1016/j.celrep.2022.110448
  
  Resource: (Cell Signaling Technology Cat# 12790, RRID:AB_2631166)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2631166
  
  What is this?
  
  RRID:AB_2631166
Visit annotations in context

Tags

RRID:AB_2631166

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124722001759
Dec 2021
www.nature.com www.nature.com

KDM6B promotes activation of the oncogenic CDK4/6-pRB-E2F pathway by maintaining enhancer activity in MYCN-amplified neuroblastoma

1
1. scibot 18 Dec 2021
  
  in Public
  
  RRID:AB_2631166
  
  DOI: 10.1038/s41467-021-27502-2
  
  Resource: (Cell Signaling Technology Cat# 12790, RRID:AB_2631166)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2631166
  
  What is this?
  
  RRID:AB_2631166
Visit annotations in context

Tags

RRID:AB_2631166

Annotators

scibot

URL

nature.com/articles/s41467-021-27502-2
Nov 2021
www.sciencedirect.com www.sciencedirect.com

RNA-binding protein FXR1 drives cMYC translation by recruiting eIF4F complex to the translation start site

1
1. scibot 03 Nov 2021
  
  in Public
  
  RRID:AB_2631166
  
  DOI: 10.1016/j.celrep.2021.109934
  
  Resource: (Cell Signaling Technology Cat# 12790, RRID:AB_2631166)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2631166
  
  What is this?
  
  RRID:AB_2631166
Visit annotations in context

Tags

RRID:AB_2631166

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124721014078
Sep 2021
www.sciencedirect.com www.sciencedirect.com

Rack1 is essential for corticogenesis by preventing p21-dependent senescence in neural stem cells

1
1. scibot 01 Sep 2021
  
  in Public
  
  RRID:AB_2631166
  
  DOI: 10.1016/j.celrep.2021.109639
  
  Resource: (Cell Signaling Technology Cat# 12790, RRID:AB_2631166)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2631166
  
  What is this?
  
  RRID:AB_2631166
Visit annotations in context

Tags

RRID:AB_2631166

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124721010822
www.sciencedirect.com www.sciencedirect.com

Discovery of synthetic lethal and tumor suppressor paralog pairs in the human genome

1
1. scibot 01 Sep 2021
  
  in Public
  
  RRID:AB_2631166
  
  DOI: 10.1016/j.celrep.2021.109597
  
  Resource: (Cell Signaling Technology Cat# 12790, RRID:AB_2631166)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2631166
  
  What is this?
  
  RRID:AB_2631166
Visit annotations in context

Tags

RRID:AB_2631166

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124721010354
Aug 2021
europepmc.org europepmc.org

Untitled document

1
1. scibot 05 Aug 2021
  
  in Public
  
  RRID:AB_2631166
  
  DOI: 10.7554/eLife.40856
  
  Resource: (Cell Signaling Technology Cat# 12790, RRID:AB_2631166)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2631166
  
  What is this?
  
  RRID:AB_2631166
Visit annotations in context

Tags

RRID:AB_2631166

Annotators

scibot

URL

europepmc.org/articles/PMC6292694/
www.sciencedirect.com www.sciencedirect.com

Untitled document

1
1. scibot 01 Aug 2021
  
  in Public
  
  RRID:AB_2631166
  
  DOI: 10.1016/j.ccell.2018.11.006
  
  Resource: (Cell Signaling Technology Cat# 12790, RRID:AB_2631166)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2631166
  
  What is this?
  
  RRID:AB_2631166
Visit annotations in context

Tags

RRID:AB_2631166

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1535610818305270
Jul 2021
link.springer.com link.springer.com

RASAL1 induces to downregulate the SCD1, leading to suppression of cell proliferation in colon cancer via LXRα/SREBP1c pathway

1
1. scibot 31 Jul 2021
  
  in Public
  
  CDK4
  
  DOI: 10.1186/s40659-019-0268-x
  
  Resource: (Cell Signaling Technology Cat# 12790, RRID:AB_2631166)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2631166
  
  What is this?
  
  RRIDCUR:Missing RRID:AB_2631166
Visit annotations in context

Tags

RRIDCUR:Missing

RRID:AB_2631166

Annotators

scibot

URL

link.springer.com/article/10.1186/s40659-019-0268-x
www.sciencedirect.com www.sciencedirect.com

Untitled document

1
1. scibot 30 Jul 2021
  
  in Public
  
  RRID:AB_2631166
  
  DOI: 10.1016/j.chembiol.2018.11.006
  
  Resource: (Cell Signaling Technology Cat# 12790, RRID:AB_2631166)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2631166
  
  What is this?
  
  RRID:AB_2631166
Visit annotations in context

Tags

RRID:AB_2631166

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2451945618304136
May 2021
www.sciencedirect.com www.sciencedirect.com

Cell size homeostasis is maintained by CDK4-dependent activation of p38 MAPK

1
1. scibot 22 May 2021
  
  in Public
  
  RRID:AB_2631166
  
  DOI: 10.1016/j.devcel.2021.04.030
  
  Resource: (Cell Signaling Technology Cat# 12790, RRID:AB_2631166)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2631166
  
  What is this?
  
  RRID:AB_2631166
Visit annotations in context

Tags

RRID:AB_2631166

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1534580721003993
www.sciencedirect.com www.sciencedirect.com

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer

1
1. scibot 07 May 2021
  
  in Public
  
  RRID:AB_2631166
  
  DOI: 10.1016/j.molcel.2020.04.027
  
  Resource: (Cell Signaling Technology Cat# 12790, RRID:AB_2631166)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2631166
  
  What is this?
  
  RRID:AB_2631166
Visit annotations in context

Tags

RRID:AB_2631166

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1097276520302690
Apr 2021
www.sciencedirect.com www.sciencedirect.com

Dual targeting of the epigenome via FACT complex and histone deacetylase is a potent treatment strategy for DIPG

1
1. scibot 14 Apr 2021
  
  in Public
  
  RRID:AB_2631166
  
  DOI: 10.1016/j.celrep.2021.108994
  
  Resource: (Cell Signaling Technology Cat# 12790, RRID:AB_2631166)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2631166
  
  What is this?
  
  RRIDCUR:Validated RRID:AB_2631166
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_2631166

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124721003089
Jan 2021
link.springer.com link.springer.com

A novel ligand of the translationally controlled tumor protein (TCTP) identified by virtual drug screening for cancer differentiation therapy

1
1. scibot 28 Jan 2021
  
  in Public
  
  RRID:AB_2631166
  
  DOI: 10.1007/s10637-020-01042-w
  
  Resource: (Cell Signaling Technology Cat# 12790, RRID:AB_2631166)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2631166
  
  What is this?
  
  RRID:AB_2631166 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_2631166

Annotators

scibot

URL

link.springer.com/article/10.1007/s10637-020-01042-w
Nov 2020
link.springer.com link.springer.com

p75NTR Promotes Astrocyte Proliferation in Response to Cortical Stab Wound

1
1. scibot 25 Nov 2020
  
  in Public
  
  anti-CDK4
  
  DOI: 10.1007/s10571-020-01006-x
  
  Resource: (Cell Signaling Technology Cat# 12790, RRID:AB_2631166)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2631166
  
  Curator comments: CDK4 antibody Cell Signaling Technology Cat# 12790
  
  What is this?
  
  RRIDCUR:Missing RRID:AB_2631166
Visit annotations in context

Tags

RRIDCUR:Missing

RRID:AB_2631166

Annotators

scibot

URL

link.springer.com/article/10.1007/s10571-020-01006-x
Sep 2020
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Three-dimensional growth of breast cancer cells potentiates the anti-tumor effects of unacylated ghrelin and AZP-531

1
1. scibot 07 Sep 2020
  
  in Public
  
  RRID:AB_2631166
  
  DOI: 10.7554/eLife.56913
  
  Resource: (Cell Signaling Technology Cat# 12790, RRID:AB_2631166)
  
  Curator: @evieth
  
  SciCrunch record: RRID:AB_2631166
  
  What is this?
  
  RRIDCUR:Validated RRID:AB_2631166
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_2631166

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC7363447/
onlinelibrary.wiley.com onlinelibrary.wiley.com

KIF15 promotes the evolution of gastric cancer cells through inhibition of reactive oxygen species‐mediated apoptosis

1
1. scibot 06 Sep 2020
  
  in Public
  
  RRID:AB_2631166
  
  DOI: 10.1002/jcp.29743
  
  Resource: (Cell Signaling Technology Cat# 12790, RRID:AB_2631166)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2631166
  
  What is this?
  
  RRID:AB_2631166 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_2631166

Annotators

scibot

URL

onlinelibrary.wiley.com/doi/10.1002/jcp.29743
www.sciencedirect.com www.sciencedirect.com

Cyclin N-Terminal Domain-Containing-1 Coordinates Meiotic Crossover Formation with Cell-Cycle Progression in a Cyclin-Independent Manner

1
1. scibot 04 Sep 2020
  
  in Public
  
  RRID:AB_2631166
  
  DOI: 10.1016/j.celrep.2020.107858
  
  Resource: (Cell Signaling Technology Cat# 12790, RRID:AB_2631166)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2631166
  
  What is this?
  
  RRIDCUR:Validated RRID:AB_2631166
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_2631166

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124720308391
Jan 2020
www.sciencedirect.com www.sciencedirect.com

MicroRNA-Mediated Suppression of the TGF-β Pathway Confers Transmissible and Reversible CDK4/6 Inhibitor Resistance

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:AB_2631166
  
  DOI: 10.1016/j.celrep.2019.02.023
  
  Resource: (Cell Signaling Technology Cat# 12790, RRID:AB_2631166)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2631166
  
  What is this?
  
  RRID:AB_2631166 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_2631166

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124719301937
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:AB_2631166
  
  DOI: 10.7554/eLife.40856
  
  Resource: (Cell Signaling Technology Cat# 12790, RRID:AB_2631166)
  
  Curator: @evieth
  
  SciCrunch record: RRID:AB_2631166
  
  What is this?
  
  RRID:AB_2631166 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_2631166

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC6292694/
www.sciencedirect.com www.sciencedirect.com

Untitled document

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:AB_2631166
  
  DOI: 10.1016/j.chembiol.2019.03.012
  
  Resource: (Cell Signaling Technology Cat# 12790, RRID:AB_2631166)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2631166
  
  What is this?
  
  RRID:AB_2631166 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_2631166

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2451945619301084
Nov 2018
onlinelibrary.wiley.com onlinelibrary.wiley.com

Testosterone regulates myosin II isoforms expression and functional activity in the rat prostate

1
1. scibot 05 Nov 2018
  
  in Public
  
  AB_2631166
  
  Curator: @anp055
  
  Resource used:
  
  (Cell Signaling Technology Cat# 12790, RRID:AB_2631166)
  
  SciCrunch record: RRID:AB_2631166
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:AB_2631166 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_2631166

Annotators

scibot

URL

onlinelibrary.wiley.com/doi/full/10.1002/pros.23702
www.sciencedirect.com www.sciencedirect.com

Mutant p53 Gains Its Function via c-Myc Activation upon CDK4 Phosphorylation at Serine 249 and Consequent PIN1 Binding

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:AB_2631166
  
  Resource used:
  
  (Cell Signaling Technology Cat# 12790, RRID:AB_2631166)
  
  SciCrunch record: RRID:AB_2631166
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:AB_2631166
Visit annotations in context

Tags

RRID:AB_2631166

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1097276517308419
www.sciencedirect.com www.sciencedirect.com

Lessons in PROTAC Design from Selective Degradation with a Promiscuous Warhead

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:AB_2631166
  
  Curator: @evieth
  
  Resource used:
  
  (Cell Signaling Technology Cat# 12790, RRID:AB_2631166)
  
  SciCrunch record: RRID:AB_2631166
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:AB_2631166 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_2631166

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2451945617303549
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A Chemoproteomic Approach to Query the Degradable Kinome Using a Multi-kinase Degrader

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:AB_2631166
  
  Resource used:
  
  (Cell Signaling Technology Cat# 12790, RRID:AB_2631166)
  
  SciCrunch record: RRID:AB_2631166
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:AB_2631166
Visit annotations in context

Tags

RRID:AB_2631166

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC6427047/

Tags

Annotators

URL

Tags

Annotators

URL

Tags

Annotators

URL

Tags

Annotators

URL

Tags

Annotators

URL

Tags

Annotators

URL

Tags

Annotators

URL

Tags

Annotators

URL

Tags

Annotators

URL

Tags

Annotators

URL

Tags

Annotators

URL

Tags

Annotators

URL

Tags

Annotators

URL

Tags

Annotators

URL

Tags

Annotators

URL

Tags

Annotators

URL

Tags

Annotators

URL

Tags

Annotators

URL

Tags

Annotators

URL

Tags

Annotators

URL

Tags

Annotators

URL

Tags

Annotators

URL

Tags

Annotators

URL

Tags

Annotators

URL

Tags

Annotators

URL

Tags

Annotators

URL

Tags

Annotators