50 Matching Annotations
  1. Apr 2024
  2. www.sciencedirect.com www.sciencedirect.com
    The MYCN 5′ UTR as a therapeutic target in neuroblastoma
    1
    1. scibot 25 Apr 2024
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      DOI: 10.1016/j.celrep.2024.114134

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    sciencedirect.com/science/article/pii/S2211124724004625
  3. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    1. scibot 13 Apr 2024
      RRID:AB_2631168

      DOI: 10.1111/bph.16373

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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.16373
  4. Nov 2023
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Discovery and biological evaluation of a potent small molecule CRM1 inhibitor for its selective ablation of extranodal NK/T cell lymphoma
    1
    1. scibot 15 Nov 2023
      RRID:AB_2631168

      DOI: 10.7554/eLife.80625

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    ncbi.nlm.nih.gov/pmc/articles/PMC10637774/
  6. www.sciencedirect.com www.sciencedirect.com
    Detection of the DNA binding of transcription factors in situ at the single-cell resolution in cultured cells by proximity ligation assay
    1
    1. scibot 03 Nov 2023
      RRID:AB_2631168

      DOI: 10.1016/j.xpro.2023.102692

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    sciencedirect.com/science/article/pii/S2666166723006597
  7. Oct 2023
  8. www.sciencedirect.com www.sciencedirect.com
    N6-methyladenosine modification promotes hepatocarcinogenesis through circ-CDYL-enriched and EpCAM-positive liver tumor-initiating exosomes
    1
    1. scibot 17 Oct 2023
      RRID:AB_2631168

      DOI: 10.1016/j.isci.2023.108022

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    sciencedirect.com/science/article/pii/S2589004223020990
  9. Jul 2023
  10. www.sciencedirect.com www.sciencedirect.com
    Premature aging and reduced cancer incidence associated with near-complete body-wide Myc inactivation
    1
    1. scibot 27 Jul 2023
      RRID:AB_2631168

      DOI: 10.1016/j.celrep.2023.112830

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    sciencedirect.com/science/article/pii/S2211124723008410
  11. Jun 2023
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    K235 acetylation couples with PSPC1 to regulate the m6A demethylation activity of ALKBH5 and tumorigenesis
    1
    1. scibot 30 Jun 2023
      RRID:AB_2631168

      DOI: 10.1038/s41467-023-39414-4

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    ncbi.nlm.nih.gov/pmc/articles/PMC10300122/
  13. www.sciencedirect.com www.sciencedirect.com
    An integrated cellular and molecular model of gastric neuroendocrine cancer evolution highlights therapeutic targets
    1
    1. scibot 23 Jun 2023
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      DOI: 10.1016/j.ccell.2023.06.001

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    sciencedirect.com/science/article/pii/S1535610823002088
  14. May 2023
  15. www.sciencedirect.com www.sciencedirect.com
    Heat shock factor 1 (HSF1) specifically potentiates c-MYC-mediated transcription independently of the canonical heat shock response
    1
    1. scibot 24 May 2023
      RRID:AB_2631168

      DOI: 10.1016/j.celrep.2023.112557

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    sciencedirect.com/science/article/pii/S2211124723005685
  16. Apr 2023
  17. www.sciencedirect.com www.sciencedirect.com
    MYC activation impairs cell-intrinsic IFNγ signaling and confers resistance to anti-PD1/PD-L1 therapy in lung cancer
    1
    1. scibot 12 Apr 2023
      RRID:AB_2631168

      DOI: 10.1016/j.xcrm.2023.101006

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    sciencedirect.com/science/article/pii/S2666379123001167
  18. Mar 2023
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Proteasome Inhibitors Silence Oncogenes in Multiple Myeloma through Localized Histone Deacetylase 3 Stabilization and Chromatin Condensation
    1
    1. scibot 29 Mar 2023
      RRID:AB_2631168

      DOI: 10.1158/2767-9764.CRC-22-0255

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    ncbi.nlm.nih.gov/pmc/articles/PMC9949381/
  20. Jan 2023
  21. www.sciencedirect.com www.sciencedirect.com
    Intersection of immune and oncometabolic pathways drives cancer hyperprogression during immunotherapy
    1
    1. scibot 19 Jan 2023
      RRID:AB_2631168

      DOI: 10.1016/j.ccell.2022.12.008

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    sciencedirect.com/science/article/pii/S1535610822005943
  22. Oct 2022
  23. www.sciencedirect.com www.sciencedirect.com
    The m6A reader IGF2BP2 regulates glutamine metabolism and represents a therapeutic target in acute myeloid leukemia
    1
    1. scibot 28 Oct 2022
      RRID:AB_2631168

      DOI: 10.1016/j.ccell.2022.10.004

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    sciencedirect.com/science/article/pii/S1535610822004950
  24. Sep 2022
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Intracellular cholesterol pools regulate oncogenic signaling and epigenetic circuitries in Early T-cell Precursor Acute Lymphoblastic Leukemia
    1
    1. scibot 02 Sep 2022
      RRID:AB_2631168

      DOI: 10.1158/2159-8290.CD-21-0551

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    ncbi.nlm.nih.gov/pmc/articles/PMC8904296/
  26. Jul 2022
  27. www.sciencedirect.com www.sciencedirect.com
    Interferon-γ resistance and immune evasion in glioma develop via Notch-regulated co-evolution of malignant and immune cells
    1
    1. scibot 13 Jul 2022
      RRID:AB_2631168

      DOI: 10.1016/j.devcel.2022.06.006

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    sciencedirect.com/science/article/pii/S1534580722004464
  28. www.embopress.org www.embopress.org
    LRH-1/NR5A2 interacts with the glucocorticoid receptor to regulate glucocorticoid resistance
    1
    1. scibot 09 Jul 2022
      RRID:AB_2631168

      DOI: 10.15252/embr.202154195

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    embopress.org/doi/10.15252/embr.202154195
  29. Mar 2022
  30. journals.lww.com journals.lww.com
    MicroRNA-101a-3p mimic ameliorates spinal cord... : Neural Regeneration Research
    1
    1. scibot 10 Mar 2022
      RRID:AB_2631168

      DOI: 10.4103/1673-5374.335164

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    journals.lww.com/nrronline/Fulltext/2022/17090/MicroRNA_101a_3p_mimic_ameliorates_spinal_cord.34.aspx
  31. Dec 2021
  32. www.sciencedirect.com www.sciencedirect.com
    Yap-Myc signaling induces pancreatic stellate cell activation through regulating glutaminolysis
    1
    1. scibot 28 Dec 2021
      13987

      DOI: 10.1016/j.yexcr.2021.113000

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    sciencedirect.com/science/article/pii/S0014482721005565
  33. www.nature.com www.nature.com
    KDM6B promotes activation of the oncogenic CDK4/6-pRB-E2F pathway by maintaining enhancer activity in MYCN-amplified neuroblastoma
    1
    1. scibot 18 Dec 2021
      RRID:AB_2631168

      DOI: 10.1038/s41467-021-27502-2

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    nature.com/articles/s41467-021-27502-2
  34. Aug 2021
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Channeling macrophage polarization by rocaglates increases macrophage resistance to Mycobacterium tuberculosis
    1
    1. scibot 16 Aug 2021
      RRID:AB_2631168

      DOI: 10.1016/j.isci.2021.102845

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    ncbi.nlm.nih.gov/pmc/articles/PMC8333345/
  36. elifesciences.org elifesciences.org
    HOXA9 promotes MYC-mediated leukemogenesis by maintaining gene expression for multiple anti-apoptotic pathways
    1
    1. scibot 15 Aug 2021
      RRID:AB_2631168

      DOI: 10.7554/eLife.64148

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    elifesciences.org/articles/64148
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    1. scibot 07 Aug 2021
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      DOI: 10.1038/s41598-018-36387-z

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    ncbi.nlm.nih.gov/pmc/articles/PMC6303337/
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    1. scibot 07 Aug 2021
      RRID:AB_2631168

      DOI: 10.1016/j.celrep.2018.11.018

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    ncbi.nlm.nih.gov/pmc/articles/PMC6302735/
  39. Jul 2021
  40. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 30 Jul 2021
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      DOI: 10.1016/j.celrep.2018.11.018

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    sciencedirect.com/science/article/pii/S2211124718317649
  41. www.fasebj.org www.fasebj.org
    Untitled document
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    1. scibot 28 Jul 2021
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      DOI: 10.1096/fj.201800687

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    fasebj.org/doi/abs/10.1096/fj.201800687
  42. www.cell.com www.cell.com
    Inhibition of YTHDF2 triggers proteotoxic cell death in MYC-driven breast cancer
    1
    1. scibot 03 Jul 2021
      RRID:AB_2631168

      DOI: 10.1016/j.molcel.2021.06.014

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    cell.com/molecular-cell/fulltext/S1097-2765(21)00493-7
  43. May 2021
  44. www.sciencedirect.com www.sciencedirect.com
    Signals of pseudo-starvation unveil the amino acid transporter SLC7A11 as key determinant in the control of Treg cell proliferative potential
    1
    1. scibot 18 May 2021
      RRID:AB_2631168

      DOI: 10.1016/j.immuni.2021.04.014

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    sciencedirect.com/science/article/pii/S107476132100176X
  45. Apr 2021
  46. www.sciencedirect.com www.sciencedirect.com
    Transcriptional control of DNA repair networks by CDK7 regulates sensitivity to radiation in MYC-driven medulloblastoma
    1
    1. scibot 28 Apr 2021
      RRID:AB_2631168

      DOI: 10.1016/j.celrep.2021.109013

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    sciencedirect.com/science/article/pii/S2211124721003272
  47. www.sciencedirect.com www.sciencedirect.com
    MAX Functions as a Tumor Suppressor and Rewires Metabolism in Small Cell Lung Cancer
    1
    1. scibot 17 Apr 2021
      AB_2631168

      DOI: 10.1016/j.ccell.2020.04.016

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    sciencedirect.com/science/article/pii/S1535610820302154
  48. Mar 2021
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PTEN dephosphorylates Abi1 to promote epithelial morphogenesis
    1
    1. scibot 09 Mar 2021
      RRID:AB_2631168

      DOI: 10.1083/jcb.201910041

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    ncbi.nlm.nih.gov/pmc/articles/PMC7480098/
  50. Feb 2021
  51. www.sciencedirect.com www.sciencedirect.com
    R-2-hydroxyglutarate attenuates aerobic glycolysis in leukemia by targeting the FTO/m6A/PFKP/LDHB axis
    1
    1. scibot 28 Feb 2021
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      DOI: 10.1016/j.molcel.2020.12.026

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    sciencedirect.com/science/article/pii/S1097276520309473
  52. Jan 2021
  53. link.springer.com link.springer.com
    The inflammatory kinase IKKα phosphorylates and stabilizes c-Myc and enhances its activity
    1
    1. scibot 21 Jan 2021
      RRID:AB_2631168

      DOI: 10.1186/s12943-021-01308-8

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    link.springer.com/article/10.1186/s12943-021-01308-8
  54. Sep 2020
  55. www.nature.com www.nature.com
    Efficiency of the four proteasome subtypes to degrade ubiquitinated or oxidized proteins
    1
    1. scibot 30 Sep 2020
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      DOI: 10.1038/s41598-020-71550-5

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    nature.com/articles/s41598-020-71550-5
  56. www.sciencedirect.com www.sciencedirect.com
    MYC Drives Temporal Evolution of Small Cell Lung Cancer Subtypes by Reprogramming Neuroendocrine Fate
    1
    1. scibot 26 Sep 2020
      RRID:AB_2631168

      DOI: 10.1016/j.ccell.2020.05.001

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    sciencedirect.com/science/article/pii/S153561082030218X
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Direct Phosphorylation and Stabilization of MYC by Aurora B Kinase Promote T-cell Leukemogenesis
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    1. scibot 16 Sep 2020
      RRID:AB_2631168

      DOI: 10.1016/j.ccell.2020.01.001

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    ncbi.nlm.nih.gov/pmc/articles/PMC7321798/
  58. www.sciencedirect.com www.sciencedirect.com
    MYC Controls the Epstein-Barr Virus Lytic Switch
    1
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      DOI: 10.1016/j.molcel.2020.03.025

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    sciencedirect.com/science/article/pii/S1097276520301933
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PTEN suppresses epithelial–mesenchymal transition and cancer stem cell activity by downregulating Abi1
    1
    1. scibot 04 Sep 2020
      RRID:AB_2631168

      DOI: 10.1038/s41598-020-69698-1

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    ncbi.nlm.nih.gov/pmc/articles/PMC7391766/
  60. www.nature.com www.nature.com
    CPSF3-dependent pre-mRNA processing as a druggable node in AML and Ewing’s sarcoma
    1
    1. scibot 03 Sep 2020
      anti-MYC

      DOI: 10.1038/s41589-019-0424-1

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      Curator comments: c-Myc (D3N8F) Rabbit mAb #13987 antibody Cell Signaling Technology Cat# 13987

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    nature.com/articles/s41589-019-0424-1
  61. Jan 2020
  62. www.sciencedirect.com www.sciencedirect.com
    A Yap-Myc-Sox2-p53 Regulatory Network Dictates Metabolic Homeostasis and Differentiation in Kras-Driven Pancreatic Ductal Adenocarcinomas
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    1. scibot 13 Jan 2020
      RRID:AB_2631168

      DOI: 10.1016/j.devcel.2019.07.022

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    sciencedirect.com/science/article/pii/S1534580719306288
  63. www.sciencedirect.com www.sciencedirect.com
    A Potent and Selective Small-Molecule Degrader of STAT3 Achieves Complete Tumor Regression In Vivo
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  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Natural molecules induce and synergize to boost expression of the human antimicrobial peptide β-defensin-3
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      DOI: 10.1073/pnas.1805298115

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  65. www.nature.com www.nature.com
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      DOI: 10.1038/s41598-018-36387-z

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  66. www.sciencedirect.com www.sciencedirect.com
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      DOI: 10.1016/j.chembiol.2019.03.012

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  67. www.sciencedirect.com www.sciencedirect.com
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      DOI: 10.1016/j.molcel.2019.02.029

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  68. Nov 2018
  69. www.sciencedirect.com www.sciencedirect.com
    Targeting Processive Transcription Elongation via SEC Disruption for MYC-Induced Cancer Therapy
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  70. www.sciencedirect.com www.sciencedirect.com
    Inosine Monophosphate Dehydrogenase Dependence in a Subset of Small Cell Lung Cancers
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  71. www.sciencedirect.com www.sciencedirect.com
    METTL14 Inhibits Hematopoietic Stem/Progenitor Differentiation and Promotes Leukemogenesis via mRNA m6A Modification
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  72. www.sciencedirect.com www.sciencedirect.com
    lncRNA Epigenetic Landscape Analysis Identifies EPIC1 as an Oncogenic lncRNA that Interacts with MYC and Promotes Cell-Cycle Progression in Cancer
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  73. www.sciencedirect.com www.sciencedirect.com
    Epigenetic Therapy Ties MYC Depletion to Reversing Immune Evasion and Treating Lung Cancer
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  74. Nov 2017
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A conformational switch regulates the ubiquitin ligase HUWE1
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