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Salicylic acid engages central metabolic regulators SnRK1 and TOR to govern immunity by differential phosphorylation of NPR1

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May 2026
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A conserved motif tunes Sidekick condensate dynamics to control tricellular junction recruitment during epithelial remodeling

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Dose-dependent mitochondrial H2O2 signaling drives toxicity or stress adaptation and longevity in fission yeast

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Apr 2026
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A phosphorelay circuit drives extracellular alkalinization in receptor kinase-mediated immune and cell-wall damage signaling

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Feb 2026
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The mitochondrial intermembrane space nuclease Nuc1 (endonuclease G) prevents mitophagy-mediated mtDNA escape in yeast

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sciencedirect.com/science/article/pii/S0960982226000060
Dec 2025
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The production of the chemokine CCL2 by corneal sensory neurons initiates anti-viral immunity at the cornea and trigeminal ganglion

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In vivo proteomic labeling reveals diverse proteomes for therapeutic targets

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Cross-species interactome analysis uncovers a conserved selective autophagy mechanism for protein quality control in plants

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sciencedirect.com:5037/science/article/pii/S1534580725006938
Oct 2025
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The plant kinesin-12 POK2 tail is a versatile interaction hub

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pmc.ncbi.nlm.nih.gov/articles/PMC12516131/
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VEL-dependent polymerization maintains the chromatin association of Polycomb proteins for the switch to epigenetic silencing

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pmc.ncbi.nlm.nih.gov/articles/PMC7618248/
Sep 2025
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The nuclear pore complex connects energy sensing to transcriptional plasticity in longevity

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Aug 2025
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Multiple golgins are required to support extracellular matrix secretion, modification, and assembly

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1. scibot 21 Aug 2025
  
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  DOI: 10.1083/jcb.202411167
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12360289/
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PALB2 and 53BP1 govern post-resection homologous recombination DNA repair

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Jul 2025
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Endogenous retrovirus-like proteins recruit UBQLN2 to stress granules and shape their functional biology

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  DOI: 10.1126/sciadv.adu6354
  
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science.org/doi/10.1126/sciadv.adu6354
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Endogenous retrovirus-like proteins recruit UBQLN2 to stress granules and shape their functional biology

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pmc.ncbi.nlm.nih.gov/articles/PMC12273755/
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Interdependence of Pasha and Drosha for localization and function of the Microprocessor in C. elegans

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  DOI: 10.1038/s41467-025-60721-5
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12219410/
Mar 2025
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Polarity-guided uneven mitotic divisions control brassinosteroid activity in proliferating plant root cells

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1. scibot 11 Mar 2025
  
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SUMO4 promotes SUMO deconjugation required for DNA double-strand-break repair

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  DOI: 10.1016/j.molcel.2025.02.004
  
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sciencedirect.com/science/article/pii/S1097276525001091
Nov 2024
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Modulation of stress granule dynamics by phosphorylation and ubiquitination in plants

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pmc.ncbi.nlm.nih.gov/articles/PMC11576400/
Jul 2024
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Biogenesis of lysosome-related organelles complex-2 is an evolutionarily ancient proto-coatomer complex

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May 2024
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Cryo-EM reveals that iRhom2 restrains ADAM17 protease activity to control the release of growth factor and inflammatory signals

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Apr 2024
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A RabGAP negatively regulates plant autophagy and immune trafficking

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Molecular basis for pH sensing in the KDEL trafficking receptor

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Mar 2024
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A dynamic ubiquitination balance of cell proliferation and endoreduplication regulators determines plant organ size

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Rim aperture of yeast autophagic membranes balances cargo inclusion with vesicle maturation

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Dec 2023
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Ubiquiton—An inducible, linkage-specific polyubiquitylation tool

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ncbi.nlm.nih.gov/pmc/articles/PMC10804999/
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A Highlights from MBoC Selection: Membrane binding of endocytic myosin-1s is inhibited by a class of ankyrin repeat proteins

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  DOI: 10.1091/mbc.E23-06-0233
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10559312/
Nov 2023
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Hepatic palmitoyl-proteomes and acyl-protein thioesterase protein proximity networks link lipid modification and mitochondria

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Aug 2023
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Myddosome clustering in IL-1 receptor signaling regulates the formation of an NF-kB activating signalosome

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  DOI: 10.15252/embr.202357233
  
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embopress.org/doi/10.15252/embr.202357233
May 2023
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A ubiquitin fusion reporter to monitor muscle proteostasis in C. elegans

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  DOI: 10.17912/micropub.biology.000824
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10163378/
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Membrane binding of endocytic myosin-1s is inhibited by a class of ankyrin repeat proteins

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  DOI: 10.1101/2023.04.26.538419
  
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biorxiv.org/content/10.1101/2023.04.26.538419v1
Apr 2023
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Transcription factor localization dynamics and DNA binding drive distinct promoter interpretations

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  DOI: 10.1016/j.celrep.2023.112426
  
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Nov 2022
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Development of single-molecule ubiquitination mediated fluorescence complementation to visualize protein ubiquitination dynamics in dendrites

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  DOI: 10.1016/j.celrep.2022.111658
  
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sciencedirect.com/science/article/pii/S2211124722015297
Aug 2022
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NMDA receptor-targeted enrichment of CaMKIIα improves fear memory

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1. scibot 16 Aug 2022
  
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  DOI: 10.1016/j.isci.2022.104864
  
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sciencedirect.com/science/article/pii/S2589004222011361
Apr 2022
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Mitochondrial dynamics regulate genome stability via control of caspase-dependent DNA damage

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The Arabidopsis F-box protein FBW2 targets AGO1 for degradation to prevent spurious loading of illegitimate small RNA

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A plant receptor domain with functional analogies to animal malectin disables ER stress responses upon infection

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ROPGAP-dependent interaction between brassinosteroid and ROP2-GTPase signaling controls pavement cell shape in Arabidopsis

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Negative charge in the RACK1 loop broadens the translational capacity of the human ribosome

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An oomycete effector subverts host vesicle trafficking to channel starvation-induced autophagy to the pathogen interface

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Spliceosomal component PRP-40 is a central regulator of microexon splicing

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The ER-embedded UBE2J1/RNF26 ubiquitylation complex exerts spatiotemporal control over the endolysosomal pathway

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Dec 2020
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Human VAPome Analysis Reveals MOSPD1 and MOSPD3 as Membrane Contact Site Proteins Interacting with FFAT-Related FFNT Motifs

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Fungal Wound Healing through Instantaneous Protoplasmic Gelation

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UBP12 and UBP13 negatively regulate the activity of the ubiquitin-dependent peptidases DA1, DAR1 and DAR2

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PIN-LIKES Coordinate Brassinosteroid Signaling with Nuclear Auxin Input in Arabidopsis thaliana

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Untitled document

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