383 Matching Annotations
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    Endogenous YAP/TAZ partitioning in TEAD condensates orchestrates the Hippo response
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    Innate immune sensing of Z-nucleic acids by ZBP1-RIPK1 axis drives neuroinflammation in Alzheimer’s disease
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    sciencedirect.com/science/article/pii/S1074761325003334
  4. Aug 2025
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    Epithelium dynamics differ in time and space when exposed to the permeation enhancers penetramax and EGTA. A head-to-head mechanistic comparison
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    A conserved mechanism for the retrieval of polyubiquitinated proteins from cilia
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    sciencedirect.com/science/article/pii/S0092867425008657
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    5-HT6 Receptor Inverse Agonists Modulate Diabetic Neuropathic Pain in Female Rats: Evidence for 5-HT6 Receptor Constitutive Activity
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    onlinelibrary.wiley.com/doi/10.1111/jnc.70179
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    Generation of three human induced pluripotent stem cell (hiPSC) lines from patients with Late-Onset Tay-Sachs disease (HEXA-related adult-onset GM2-gangliosidosis)
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    Combined MEK and PARP inhibition enhances radiation response in rectal cancer
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  11. Jul 2025
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    Protocol for CRISPR-based manipulation and visualization of endogenous α-synuclein in cultured mouse hippocampal neurons
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    An updated inventory of genes essential for oxidative phosphorylation identifies a mitochondrial origin in familial Ménière’s disease
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    Selective loss of Scn2a in ventral tegmental area dopaminergic neurons leads to dopamine system hypofunction and autistic-like behaviors
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    Optimizing standardized lab-grown skin substitutes reveals a proliferation-differentiation switch based in ascorbic acid
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    Microglial α7-Nicotinic Acetylcholine Receptors Are Expressed in Mitochondria Rather Than on the Plasma Membrane: Roles in Mitochondrial Function
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    Comprehensive genetic profiling of sensorineural hearing loss using an integrative diagnostic approach
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  19. Jun 2025
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    Identification of a senescence-associated transcriptional program in skeletal muscle of cachectic pancreatic-tumor bearing mice
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    Generation and characterization of human iPSC lines from two patients with therapy-resistant epilepsy carrying nonsense heterozygous variants in the SMC1A gene
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  22. May 2025
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    Polyunsaturated fatty acids in lipid membranes regulate human neuronal function and amyloid-β production
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    Selective removal of astrocytic PERK protects against glymphatic impairment and decreases toxic aggregation of β-amyloid and tau
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    Sex-specific loss of mitochondrial membrane integrity in the auditory brainstem of a mouse model of Fragile X Syndrome
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    Stromal lipid species dictate melanoma metastasis and tropism
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  28. Apr 2025
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    Time Release Ion Matrix Regenerates Dystrophic Skeletal Muscle
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    Generation of an induced pluripotent stem cell (iPSC) line (INNDSUi0010-A) from a patient with Anti-MDA5 antibody-positive dermatomyositis
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    Treacle’s ability to form liquid-like phase condensates is essential for nucleolar fibrillar center assembly, efficient rRNA transcription and processing, and rRNA gene repair
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    Protocol to identify endogenous proximal proteins using biotinylation by antibody recognition
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  34. Mar 2025
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    Differential Effects of Cocaine Self-Administration Regimens on Incubation of Cocaine Craving and Nucleus Accumbens Neuronal Ensembles Activated by Cocaine-Associated Context
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    APOE genotype determines cell-type-specific pathological landscape of Alzheimer’s disease
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    β-catenin-driven endomesoderm specification is a Bilateria-specific novelty
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    Simultaneous CRISPR screening and spatial transcriptomics reveal intracellular, intercellular, and functional transcriptional circuits
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    Single-nucleus and spatial landscape of the sub-ventricular zone in human glioblastoma
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    Experimental horizontal transfer of phage-derived genes to Drosophila confers innate immunity to parasitoids
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    Molecular tag for promoting N-glycan maturation in the cargo receptor-mediated secretion pathway
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    CRL3ARMC5 ubiquitin ligase and Integrator phosphatase form parallel mechanisms to control early stages of RNA Pol II transcription
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  53. Nov 2024
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    Intra-tumoral YAP and TAZ heterogeneity drives collective NSCLC invasion that is targeted by SUMOylation inhibitor TAK-981
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    Targeting BCL2 with Venetoclax Enhances the Efficacy of the KRASG12D Inhibitor MRTX1133 in Pancreatic Cancer
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  60. Oct 2024
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  62. Sep 2024
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  68. Aug 2024
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    Generation and characterization of human-derived induced pluripotent stem cell line (IGIBi010-A) from a patient with neurodegenerative disease phenotype carrying mutation in SQSTM1/p62 gene
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    A single pair of pharyngeal neurons functions as a commander to reject high salt in Drosophila melanogaster
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  75. Jul 2024
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    Intracellular tau fragment droplets serve as seeds for tau fibrils
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    Molecular Logic of Synaptic Diversity Between Drosophila Tonic and Phasic Motoneurons
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    Characterising replisome disassembly in human cells
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    Generation of four induced pluripotent stem cell lines (KEIUi004-A, KEIUi005-A, KEIUi006-A, and KEIUi007-A) from patients with sensorineural hearing loss with mutation in EYA4 gene
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    Ttm50 facilitates calpain activation by anchoring it to calcium stores and increasing its sensitivity to calcium
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    Astrocytes facilitate gabazine-evoked electrophysiological hyperactivity and distinct biochemical responses in mature neuronal cultures
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  82. www.biorxiv.org www.biorxiv.org
    Sex-specific loss of mitochondrial membrane integrity and mass in the auditory brainstem of a mouse model of Fragile X syndrome
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    biorxiv.org/content/10.1101/2024.07.02.601649v1
  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Multivalent GU-rich oligonucleotides sequester TDP-43 in the nucleus by inducing high molecular weight RNP complexes
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  84. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Preventing loss of sirt1 lowers mitochondrial oxidative stress and preserves c2c12 myotube diameter in an in vitro model of cancer cachexia
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    Cell-specific inhibitory modulation of sound processing in the auditory thalamus
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  86. Jun 2024
  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    KDM5-mediated transcriptional activation of ribosomal protein genes alters translation efficiency to regulate mitochondrial metabolism in neurons
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  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Avoiding Alkaline Taste through Ionotropic Receptors
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  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NLRC5 senses NAD+ depletion, forming a PANoptosome and driving PANoptosis and inflammation
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    KIF22 regulates mitosis and proliferation of chondrocyte cells.
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    The neural basis of resting-state fMRI functional connectivity in fronto-limbic circuits revealed by chemogenetic manipulation
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  92. May 2024
  93. www.sciencedirect.com www.sciencedirect.com
    TBK1 is ubiquitinated by TRIM5α to assemble mitophagy machinery
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    LncRNA TubAR complexes with TUBB4A and TUBA1A to promote microtubule assembly and maintain myelination
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    Cooperation of Various Cytoskeletal Components Orchestrates Intercellular Spread of Mitochondria between B Cells through Tunnelling Nanotubes
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    Vascular architecture regulates mesenchymal stromal cell heterogeneity via P53-PDGF signaling in the mouse incisor
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  97. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ATG9B regulates bacterial internalization via actin rearrangement
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    Tolerance thresholds underlie responses to DNA damage during germline development
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  99. Apr 2024
  100. www.embopress.org www.embopress.org
    The regulatory relationship between NAMPT and PD-L1 in cancer and identification of a dual-targeting inhibitor
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    embopress.org/doi/full/10.1038/s44321-024-00051-z
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