300 Matching Annotations
  1. Last 7 days
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A single pair of pharyngeal neurons functions as a commander to reject high salt in Drosophila melanogaster
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    1. scibot 10 Apr 2024
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      DOI: 10.7554/eLife.93464

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    ncbi.nlm.nih.gov/pmc/articles/PMC10994663/
  3. Apr 2024
  4. www.sciencedirect.com www.sciencedirect.com
    Human V-ATPase function is positively and negatively regulated by TLDc proteins
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    sciencedirect.com/science/article/pii/S0969212624000911
  5. 52.53.155.43 52.53.155.43
    Mechanical strengthening of cell-cell adhesion during mouse embryo compaction
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    1. scibot 05 Apr 2024
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    52.53.155.43/870c1a0ff31c21208e246618afb62f0f1069de5c/1-s2.0-S000634952400208X-main-html.html
  6. Mar 2024
  7. www.sciencedirect.com www.sciencedirect.com
    Pooled CRISPR screening of high-content cellular phenotypes using ghost cytometry
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    1. scibot 29 Mar 2024
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      DOI: 10.1016/j.crmeth.2024.100737

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    sciencedirect.com/science/article/pii/S2667237524000626
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    SOX17/ETV2 improves the direct reprogramming of adult fibroblasts to endothelial cells
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    sciencedirect.com/science/article/pii/S2667237524000572
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    Generation and characterization of iPSC lines from Friedreich’s ataxia patient (FRDA) with GAA.TTC repeat expansion in the Frataxin (FXN) gene’s first intron (IGIBi016-A) and a non-FRDA healthy control individual (IGIBi017-A)
    2
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    sciencedirect.com/science/article/pii/S1873506124000801
  10. 52.53.155.43 52.53.155.43
    Characterization of novel PHEX variants in X-linked hypophosphatemic rickets and genotype-PHEX activity correlation
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    1. scibot 08 Mar 2024
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      DOI: 10.1210/clinem/dgae120

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    52.53.155.43/1d01e32c994e23a11172d81a053fa3471dc9f192/dgae120-html.html
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    Cardiomyocyte-fibroblast interaction regulates ferroptosis and fibrosis after myocardial injury
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    1. scibot 07 Mar 2024
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    sciencedirect.com/science/article/pii/S2589004224004401
  12. Feb 2024
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    Developmental remodeling repurposes larval neurons for sexual behaviors in adult Drosophila
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    1. scibot 28 Feb 2024
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    sciencedirect.com/science/article/pii/S0960982224001027
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    p53R245W mutation fuels cancer initiation and metastases in NASH-driven liver tumorigenesis
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    1. scibot 27 Feb 2024
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      DOI: 10.1158/2767-9764.CRC-23-0218

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    aacrjournals.org/cancerrescommun/article/3/12/2640/732161/p53R245W-Mutation-Fuels-Cancer-Initiation-and
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    Evolutionary analysis identifies a Golgi pathway and correlates lineage-specific factors with endomembrane organelle emergence in apicomplexans
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    1. scibot 23 Feb 2024
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      DOI: 10.1016/j.celrep.2024.113740

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    sciencedirect.com/science/article/pii/S2211124724000688
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    DLK signaling in axotomized neurons triggers complement activation and loss of upstream synapses
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    1. scibot 16 Feb 2024
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      DOI: 10.1016/j.celrep.2024.113801

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    sciencedirect.com/science/article/pii/S2211124724001293
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    Phospholipids with two polyunsaturated fatty acyl tails promote ferroptosis
    1
    1. scibot 16 Feb 2024
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      DOI: 10.1016/j.cell.2024.01.030

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    sciencedirect.com/science/article/pii/S0092867424000679
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    Generation of an induced pluripotent stem cell line (SYSUSCi004-A) from a patient with Infantile Malignant Osteopetrosis
    1
    1. scibot 15 Feb 2024
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    sciencedirect.com/science/article/pii/S187350612400028X
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    Familial Alzheimer mutations stabilize synaptotoxic γ-secretase-substrate complexes
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    sciencedirect.com/science/article/pii/S2211124724000895
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    Generation of two human induced pluripotent stem cell lines, IGIBi012-A and IGIBi013-A from Friedreich’s ataxia (FRDA) patients with homozygous GAA repeat expansion in FXN gene
    1
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    sciencedirect.com/science/article/pii/S1873506124000382
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    PARP1-DNA co-condensation drives DNA repair site assembly to prevent disjunction of broken DNA ends
    1
    1. scibot 09 Feb 2024
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      DOI: 10.1016/j.cell.2024.01.015

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    sciencedirect.com/science/article/pii/S0092867424000527
  22. journals.plos.org journals.plos.org
    Flow cytometry-based quantification of genome editing efficiency in human cell lines using the L1CAM gene
    1
    1. scibot 03 Feb 2024
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      DOI: 10.1371/journal.pone.0294146

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    journals.plos.org/plosone/article
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A time window for rescuing dying retinal ganglion cells
    1
    1. scibot 03 Feb 2024
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      DOI: 10.1186/s12964-023-01427-3

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    ncbi.nlm.nih.gov/pmc/articles/PMC10832163/
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SOX2 and SOX9 Expression in Developing Postnatal Opossum (Monodelphis domestica) Cortex
    1
    1. scibot 01 Feb 2024
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      DOI: 10.3390/biom14010070

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    ncbi.nlm.nih.gov/pmc/articles/PMC10813269/
  25. Jan 2024
  26. www.sciencedirect.com www.sciencedirect.com
    BLM and BRCA1-BARD1 coordinate complementary mechanisms of joint DNA molecule resolution
    1
    1. scibot 25 Jan 2024
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      DOI: 10.1016/j.molcel.2023.12.040

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    sciencedirect.com/science/article/pii/S1097276523010869
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    Cholinergic signaling via muscarinic M1 receptor confers resistance to docetaxel in prostate cancer
    1
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      DOI: 10.1016/j.xcrm.2023.101388

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    sciencedirect.com/science/article/pii/S2666379123006171
  28. www.jneurosci.org www.jneurosci.org
    Protein 4.1N plays a cell-type specific role in hippocampal glutamatergic synapse regulation
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    1. scibot 11 Jan 2024
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      DOI: 10.1523/JNEUROSCI.0185-23.2023

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    jneurosci.org/content/43/49/8336
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Gbb glutathionylation promotes its proteasome-mediated degradation to inhibit synapse growth
    1
    1. scibot 05 Jan 2024
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      DOI: 10.1083/jcb.202202068

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    ncbi.nlm.nih.gov/pmc/articles/PMC10316630/
  30. Dec 2023
  31. www.embopress.org www.embopress.org
    The EMBO Journal - 2023 - Pelzer - Cell fragmentation in mouse preimplantation embryos induced by ectopic activation of the-html.html
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    1. scibot 26 Dec 2023
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      DOI: 10.15252/embj.2023114415

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    embopress.org/doi/10.15252/embj.2023114415
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    Generation and characterization of two human iPSC lines, IGIBi014-A and IGIBi015-A, from Friedreich's ataxia (FRDA) patients with pathogenic (GAA/TTC)n repeat expansion in first intron of the Frataxin (FXN) gene
    1
    1. scibot 23 Dec 2023
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    sciencedirect.com/science/article/pii/S1873506123002751
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    Serine-129 phosphorylation of α-synuclein is an activity-dependent trigger for physiologic protein-protein interactions and synaptic function
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      DOI: 10.1016/j.neuron.2023.11.020

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    sciencedirect.com/science/article/pii/S0896627323008942
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    Integrated omics landscape of hepatocellular carcinoma suggests proteomic subtypes for precision therapy
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      DOI: 10.1016/j.xcrm.2023.101315

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    sciencedirect.com/science/article/pii/S2666379123005098
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    Aberrant axon initial segment plasticity and intrinsic excitability of ALS hiPSC motor neurons
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      DOI: 10.1016/j.celrep.2023.113509

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    sciencedirect.com/science/article/pii/S2211124723015218
  36. Nov 2023
  37. www.sciencedirect.com www.sciencedirect.com
    Pigmented skin exhibits accelerated wound healing compared to the nonpigmented skin in Guinea pig model
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      DOI: 10.1016/j.isci.2023.108159

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    sciencedirect.com/science/article/pii/S2589004223022368
  38. Oct 2023
  39. www.sciencedirect.com www.sciencedirect.com
    Identification of hyperoxidized PRDX3 as a ferroptosis marker reveals ferroptotic damage in chronic liver diseases
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    sciencedirect.com/science/article/pii/S1097276523007529
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    Sequential activation of E2F via Rb degradation and c-Myc drives resistance to CDK4/6 inhibitors in breast cancer
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      DOI: 10.1016/j.celrep.2023.113198

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    sciencedirect.com/science/article/pii/S221112472301210X
  41. www.sciencedirect.com www.sciencedirect.com
    Peroxisomal ERK mediates Akh/glucagon action and glycemic control
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    sciencedirect.com/science/article/pii/S2211124723012123
  42. www.cell.com www.cell.com
    Dental Pulp Stem Cells Accelerate Wound Healing through CCL2 induced M2 Macrophages Polarization
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      DOI: 10.1016/j.isci.2023.108043

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    cell.com/iscience/abstract/S2589-0042(23)02120-X
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An evolutionarily nascent architecture underlying the formation and emergence of biomolecular condensates
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      DOI: 10.1016/j.celrep.2023.112955

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    ncbi.nlm.nih.gov/pmc/articles/PMC10529244/
  44. Sep 2023
  45. www.sciencedirect.com www.sciencedirect.com
    Discordant interactions between YAP1 and polycomb group protein SCML2 determine cell fate
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      DOI: 10.1016/j.isci.2023.107964

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    sciencedirect.com/science/article/pii/S2589004223020412
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    Hyperglycemia-regulated tRNA-derived fragment tRF-3001a propels neurovascular dysfunction in diabetic mice
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      DOI: 10.1016/j.xcrm.2023.101209

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    Luteal Lipid Droplets: A Novel Platform for Steroid Synthesis
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    Image-based and machine learning-guided multiplexed serology test for SARS-CoV-2
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    Molecular logic of synaptic diversity between Drosophila tonic and phasic motoneurons
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    Sex shapes cell-type-specific transcriptional signatures of stress exposure in the mouse hypothalamus
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    A dual hit of α-synuclein internalization and immune challenge leads to formation and maintenance of Lewy body-like inclusions in human dopaminergic neurons
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    Bacterial effector restricts liquid-liquid phase separation of ZPR1 to antagonize host UPRER
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    The C-terminus of Sudan ebolavirus VP40 contains a functionally important CXnC motif, a target for redox modifications
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  65. May 2023
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    Kinetics of RTK activation determine ERK reactivation and resistance to dual BRAF/MEK inhibition in melanoma
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    Conditional deletion of LRRC8A in the brain reduces stroke damage independently of swelling-activated glutamate release
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    Stress-induced perturbations in intracellular amino acids reprogram mRNA translation in osmoadaptation independently of the ISR
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    Fructose-1,6-bisphosphatase is a nonenzymatic safety valve that curtails AKT activation to prevent insulin hyperresponsiveness
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    A plasma membrane-associated glycolytic metabolon is functionally coupled to KATP channels in pancreatic α and β cells from humans and mice
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    Proximity labeling reveals OTUD3 as a DNA-binding deubiquitinase of cGAS
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    Generation of induced pluripotent stem cells (iPSCs) from a microvillus inclusion disease patient with a homozygous missense mutation in UNC45A
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    Illuminating cellular and extracellular vesicle-mediated communication via a split-Nanoluc reporter in vitro and in vivo
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    Prenatal low-dose methylmercury exposure causes premature neuronal differentiation and autism-like behaviors in a rodent model
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    Structural and functional integration of human forebrain organoids with the injured adult rat visual system
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    VAP-A intrinsically disordered regions enable versatile tethering at membrane contact sites
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    Generation of two induced pluripotent stem cell lines from individuals without auditory disorders
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  100. Dec 2022
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    The EMT transcription factor ZEB1 governs a fitness-promoting but vulnerable DNA replication stress response
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    Inhibition of the LRRC8A channel promotes microglia/macrophage phagocytosis and improves outcomes after intracerebral hemorrhagic stroke
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    Systemic administration of novel engineered AAV capsids facilitates enhanced transgene expression in the macaque CNS
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    Heat shock factor HSF1 regulates BDNF gene promoters upon acute stress in the hippocampus, together with pCREB
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    Membrane phosphoinositides regulate GPCR-β-arrestin complex assembly and dynamics
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  110. Oct 2022
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    Zebrafish Neuromesodermal Progenitors Undergo a Critical State Transition in vivo
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    Generation of two induced pluripotent stem cell lines from dilated cardiomyopathy patients carrying TTN mutations
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    The FDA-approved drug Auranofin has a dual inhibitory effect on SARS-CoV-2 entry and NF-κB signaling
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    Generation of three human iPSC lines from patients with Huntington’s Disease with different CAG lengths and human control iPSC line from a healthy donor
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  120. Sep 2022
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    Uncompetitive, adduct-forming SARM1 inhibitors are neuroprotective in preclinical models of nerve injury and disease
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  134. Jul 2022
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  139. May 2022
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    The non-essential TSC complex component TBC1D7 restricts tissue mTORC1 signaling and brain and neuron growth
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  142. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Role of ATF3 in Neuronal Differentiation and Development of Neuronal Networks in Opossum Postnatal Cortical Cultures
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    Interactomic analysis reveals a homeostatic role for the HIV restriction factor TRIM5α in mitophagy
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  144. Apr 2022
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    ARVCF catenin controls force production during vertebrate convergent extension
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    Liquid phase separation of NEMO induced by polyubiquitin chains activates NF-κB
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  147. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Extracellular tau oligomers affect extracellular glutamate handling by astrocytes through downregulation of GLT-1 expression and impairment of NKA1A2 function
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  148. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The non-adrenergic imidazoline-1 receptor protein Nischarin is a key regulator of astrocyte glutamate uptake
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  149. Mar 2022
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    G protein-coupled estrogen receptor activates cell type-specific signaling pathways in cortical cultures: relevance to the selective loss of astrocytes
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    Neutral ceramidase-dependent regulation of macrophage metabolism directs intestinal immune homeostasis and controls enteric infection
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    Mucus sialylation determines intestinal host-commensal homeostasis
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    Generation and characterization of IMAGINi013-A, an induced pluripotent stem cell line generated from a healthy donor
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  154. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    hsa_circ_0077837 Alleviated the Malignancy of Non-Small Cell Lung Cancer by Regulating the miR-1178-3p/APITD1 Axis
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    A hotspot mutation targeting the R-RAS2 GTPase acts as a potent oncogenic driver in a wide spectrum of tumors
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    Müller glia fused with adult stem cells undergo neural differentiation in human retinal models
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    Deletion of STAT3 from Foxd1 cell population protects mice from kidney fibrosis by inhibiting pericytes trans-differentiation and migration
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    Moraxella catarrhalis evades neutrophil oxidative stress responses providing a safer niche for nontypeable Haemophilus influenzae
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    Insulin signaling couples growth and early maturation to cholesterol intake in Drosophila
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    Paradoxical neuronal hyperexcitability in a mouse model of mitochondrial pyruvate import deficiency
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  161. 52.53.155.43 52.53.155.43
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  162. Feb 2022
  163. www.sciencedirect.com www.sciencedirect.com
    The landscape of pioneer factor activity reveals the mechanisms of chromatin reprogramming and genome activation
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    Molecular and neuronal mechanisms for amino acid taste perception in the Drosophila labellum
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    Naegleria’s mitotic spindles are built from unique tubulins and highlight core spindle features
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  166. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Differential regulation of cranial and cardiac neural crest by serum response factor and its cofactors
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  167. Jan 2022
  168. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    A new therapeutic effect of fenofibrate in Duchenne muscular dystrophy: The promotion of myostatin degradation
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    Regulation of reverse electron transfer at mitochondrial complex I by unconventional Notch action in cancer stem cells
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    Fine-tuning of β-catenin in mouse thymic epithelial cells is required for postnatal T-cell development
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  171. Dec 2021
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    β-catenin links cell seeding density to global gene expression during mouse embryonic stem cell differentiation
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    CHK1 protects oncogenic KRAS-expressing cells from DNA damage and is a target for pancreatic cancer treatment
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  174. Nov 2021
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    Derivation of iPS cell line (ICGi032-A) from a patient affected with fragile X syndrome
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    Dendro-somatic synaptic inputs to ganglion cells contradict receptive field and connectivity conventions in the mammalian retina
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    Generation of three induced pluripotent stem cell lines from hypertrophic cardiomyopathy patients carrying TNNI3 mutations
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  178. Oct 2021
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    Plasmacytoid dendritic cell activation is dependent on coordinated expression of distinct amino acid transporters
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    TRPM7 is critical for short-term synaptic depression by regulating synaptic vesicle endocytosis
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    Phase separation drives RNA virus-induced activation of the NLRP6 inflammasome
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    Synaptogenic activity of the axon guidance molecule Robo2 underlies hippocampal circuit function
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    Noradrenergic circuit control of non-REM sleep substates
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    Generation of a heterozygous SOX10 knockout human embryonic stem cell line using CRISPR/Cas9 technology
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    5-Hydroxymethyltubercidin exhibits potent antiviral activity against flaviviruses and coronaviruses, including SARS-CoV-2
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    Diversity and function of motile ciliated cell types within ependymal lineages of the zebrafish brain
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  187. Sep 2021
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    Anterior thalamic nuclei neurons sustain memory
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    TRPC3 and NALCN channels drive pacemaking in substantia nigra dopaminergic neurons
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    Gum Arabic supplementation prevents loss of learning and memory through stimulation of mitochondrial function in the hippocampus of type 2 diabetic rats
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    Restoration of KCC2 Membrane Localization in Striatal Dopamine D2 Receptor-Expressing Medium Spiny Neurons Rescues Locomotor Deficits in HIV Tat-Transgenic Mice
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    Compromised mitochondrial quality control triggers lipin1-related rhabdomyolysis
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    Secreted retrovirus-like GAG-domain-containing protein PEG10 is regulated by UBE3A and is involved in Angelman syndrome pathophysiology
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    Impairment of Angiogenesis by Fatty Acid Synthase Inhibition Involves mTOR Malonylation
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  201. Jul 2021
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    An Intrinsically Disordered Region in OSBP Acts as an Entropic Barrier to Control Protein Dynamics and Orientation at Membrane Contact Sites
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    Mechanism of Acetic Acid Gustatory Repulsion in Drosophila
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    α-Ketoglutarate links p53 to cell fate during tumour suppression
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    Genetic Interactions between the Aurora Kinases Reveal New Requirements for AURKB and AURKC during Oocyte Meiosis
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    TRPC1/5-CaV3 Complex Mediates Leptin-Induced Excitability in Hypothalamic Neurons
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    Cerebellar spongiform degeneration is accompanied by metabolic, cellular, and motor disruption in male rats with portacaval anastomosis
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    The autophagy protein Becn1 improves insulin sensitivity by promoting adiponectin secretion via exocyst binding
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    Axonal generation of amyloid-β from palmitoylated APP in mitochondria-associated endoplasmic reticulum membranes
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    Repression of endogenous retroviruses prevents antiviral immune response and is required for mammary gland development
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    Ubiquitin-dependent remodeling of the actin cytoskeleton drives cell fusion
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      Goat Alexa Fluor Plus 488 anti mouse

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    Pathogenic LMNA variants disrupt cardiac lamina-chromatin interactions and de-repress alternative fate genes
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    CHK1 Inhibitor Blocks Phosphorylation of FAM122A and Promotes Replication Stress
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