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From stem cells to somites: Revealing genetic and exogenous factors of human embryogenesis

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1. scibot 08 Aug 2026
  
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  DOI: 10.1016/j.stemcr.2026.103023
  
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sciencedirect.com/science/article/pii/S2213671126002341
Jul 2026
www.science.org www.science.org

Engineered antibodies bypass bacterial immune evasion to drive complement-mediated protection against lethal infections

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1. scibot 22 Jul 2026
  
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  DOI: 10.1126/scitranslmed.adx4108
  
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science.org/doi/10.1126/scitranslmed.adx4108
Jun 2026
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TRIM21 induces selective autophagy of viruses and bacteria

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1. scibot 05 Jun 2026
  
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  DOI: 10.1016/j.molcel.2026.04.031
  
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sciencedirect.com/science/article/pii/S1097276526002856
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Cortical prostaglandin D2 contributes to behavioral sensitization and anxiety in peripheral inflammation

1
1. scibot 05 Jun 2026
  
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  DOI: 10.1016/j.celrep.2026.117492
  
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sciencedirect.com/science/article/pii/S221112472600570X
May 2026
www.nature.com www.nature.com

Establishment of a xenograft model of endometriosis-associated fibrosis using human immortalized endometrial stromal cells overexpressing HOXC8

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1. scibot 15 May 2026
  
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  DOI: 10.1038/s41598-026-41956-8
  
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nature.com/articles/s41598-026-41956-8
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BPS Publications

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1. scibot 05 May 2026
  
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  DOI: 10.1111/bph.70469
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.70469
Apr 2026
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BRCA2-dependent maturation of nascent strands during DNA replication

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1. scibot 07 Apr 2026
  
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  DOI: 10.1016/j.molcel.2026.03.012
  
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sciencedirect.com/science/article/pii/S1097276526001681
Jan 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Targeting uPARAP with an antibody-drug conjugate exhibits efficacy against mesothelioma and synergizes with cisplatin

1
1. scibot 23 Jan 2026
  
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  DOI: 10.1158/2767-9764.CRC-25-0381
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12810491/
Nov 2025
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ARID1A stabilizes non-homologous end joining factors at DNA breaks induced by the G4 ligand pyridostatin

1
1. scibot 23 Nov 2025
  
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  DOI: 10.1016/j.celrep.2025.116277
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12457572/
54.241.53.176 54.241.53.176

1-s2.0-S258900422502259X-main-html.html

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1. scibot 13 Nov 2025
  
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  RRID:AB_2636929
  
  DOI: 10.1016/j.isci.2025.113998
  
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54.241.53.176/9c0cacf676d99146b529f932bb08c69d44f0df44/1-s2.0-S258900422502259X-main-html.html
Oct 2025
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Cryo-EM structure of endogenous Pfs230:Pfs48/45 complex with six antibodies reveals mechanisms of malaria transmission-blocking activity

1
1. scibot 11 Oct 2025
  
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  DOI: 10.1016/j.immuni.2025.09.014
  
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sciencedirect.com/science/article/pii/S107476132500425X
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Nuclear Galectin-1 promotes KRAS-dependent activation of pancreatic cancer stellate cells

1
1. scibot 03 Oct 2025
  
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  DOI: 10.1073/pnas.2424051122
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12002210/
Sep 2025
www.biorxiv.org www.biorxiv.org

The axonal ER couples translation and secretion machineries for local delivery of axonal transmembrane proteins to promote axonal development

1
1. scibot 18 Sep 2025
  
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  RRID:AB_2636929
  
  DOI: 10.1101/2025.09.09.674816
  
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biorxiv.org/content/10.1101/2025.09.09.674816v1
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

ARID1A stabilizes non-homologous end joining factors at DNA breaks induced by the G4 ligand pyridostatin

1
1. scibot 12 Sep 2025
  
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  RRID:AB_2636929
  
  DOI: 10.1016/j.celrep.2025.116277
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12457572/
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Pan-carcinoma sialyl-Tn-targeting expands CAR therapy to solid tumors

1
1. scibot 09 Sep 2025
  
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  DOI: 10.1016/j.xcrm.2025.102350
  
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sciencedirect.com/science/article/pii/S2666379125004239
Aug 2025
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A CDK11-dependent RNA polymerase II pause-checkpoint precedes CDK9-mediated transition to transcriptional elongation

1
1. scibot 26 Aug 2025
  
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  DOI: 10.1016/j.molcel.2025.08.001
  
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sciencedirect.com/science/article/pii/S1097276525006513
Jul 2025
www.cell.com www.cell.com

Controlling mitochondrial membrane architecture via MIC60 determines viral replication to promote anti-viral immunity

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1. scibot 15 Jul 2025
  
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  RRID:AB_2636929
  
  DOI: 10.1016/j.celrep.2025.115922
  
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cell.com/cell-reports/abstract/S2211-1247(25)00693-X
Jun 2025
onlinelibrary.wiley.com onlinelibrary.wiley.com

Integrin β6 expression in colorectal cancer cells promotes liver metastasis through enhanced adhesion to endothelial fibronectin

1
1. scibot 11 Jun 2025
  
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  RRID:AB_2636929
  
  DOI: 10.1002/ijc.35504
  
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onlinelibrary.wiley.com/doi/10.1002/ijc.35504
May 2025
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LIMK1 variants are associated with divergent endocrinological phenotypes and altered exocytosis dynamics

1
1. scibot 18 May 2025
  
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  DOI: 10.1016/j.isci.2025.112585
  
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sciencedirect.com/science/article/pii/S2589004225008466
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The development of a canine single-chain phage antibody library to isolate recombinant antibodies for use in translational cancer research

1
1. scibot 17 May 2025
  
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  DOI: 10.1016/j.crmeth.2025.101008
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12049728/
Feb 2025
physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com

Dietary nitrate supplementation mitigates age-related changes at the neuromuscular junction in mice

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1. scibot 27 Feb 2025
  
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  DOI: 10.1113/JP287592
  
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2. scibot 27 Feb 2025
  
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  DOI: 10.1113/JP287592
  
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physoc.onlinelibrary.wiley.com/doi/10.1113/JP287592
Jan 2025
52.53.155.43 52.53.155.43

1-s2.0-S2212877824002229-main-html.html

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1. scibot 03 Jan 2025
  
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  DOI: 10.1016/j.molmet.2024.102091
  
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52.53.155.43/ff53ca808409e557edfcd52846690258be8d728c/1-s2.0-S2212877824002229-main-html.html
Nov 2024
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PP2A licenses the FANCD2/FANCI complex for chromosome loading

2
1. scibot 14 Nov 2024
  
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  DOI: 10.1016/j.celrep.2024.114971
  
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2. scibot 14 Nov 2024
  
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  DOI: 10.1016/j.celrep.2024.114971
  
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sciencedirect.com/science/article/pii/S2211124724013226
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β2-integrins control HIF1α activation in human neutrophils

1
1. scibot 07 Nov 2024
  
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  RRID:AB_2636929
  
  DOI: 10.3389/fimmu.2024.1406967
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11513320/
Sep 2024
onlinelibrary.wiley.com onlinelibrary.wiley.com

Impaired cellular copper regulation in the presence of ApoE4

1
1. scibot 27 Sep 2024
  
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  DOI: 10.1111/jnc.16198
  
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onlinelibrary.wiley.com/doi/10.1111/jnc.16198
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ATGL/CGI-58-Dependent Hydrolysis of a Lipid Storage Pool in Murine Enterocytes

1
1. scibot 25 Sep 2024
  
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  RRID:AB_2687969
  
  DOI: 10.1016/j.celrep.2019.07.030
  
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sciencedirect.com/science/article/pii/S2211124719309271
Aug 2024
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Cordycepin exhibits both antiviral and anti-inflammatory effects against dengue virus infection

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1. scibot 28 Aug 2024
  
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  DOI: 10.1016/j.isci.2024.110711
  
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sciencedirect.com/science/article/pii/S2589004224019369
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Human induced pluripotent stem cells for live cell cycle monitoring and endogenous gene activation

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1. scibot 20 Aug 2024
  
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  DOI: 10.1016/j.scr.2024.103531
  
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sciencedirect.com/science/article/pii/S1873506124002290
www.embopress.org www.embopress.org

HOIP limits anti-tumor immunity by protecting against combined TNF and IFN-gamma-induced apoptosis

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1. scibot 02 Aug 2024
  
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  P0260
  
  DOI: 10.15252/embr.202153391
  
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embopress.org/doi/full/10.15252/embr.202153391
Jun 2024
www.cell.com www.cell.com

Chemotherapy-induced intestinal epithelial damage directly promotes galectin-9-driven modulation of T cell behavior

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1. scibot 29 Jun 2024
  
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  DOI: 10.1016/j.isci.2024.110072
  
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cell.com/iscience/abstract/S2589-0042(24)01297-5
May 2024
www.biorxiv.org www.biorxiv.org

Spatiotemporal proteomics reveals the biosynthetic lysosomal membrane protein interactome in neurons

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1. scibot 23 May 2024
  
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  DOI: 10.1101/2024.05.16.594502
  
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biorxiv.org/content/10.1101/2024.05.16.594502v1
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Analysis of tumor-associated AXIN1 missense mutations identifies variants that activate β-catenin signaling

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1. scibot 04 May 2024
  
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  RRID:AB_2636929
  
  DOI: 10.1158/0008-5472.CAN-23-2268
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11063763/
Mar 2024
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Locally misfolded HER2 expressed on cancer cells is a promising target for development of cancer-specific antibodies

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1. scibot 12 Mar 2024
  
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  RRID:AB_2636929
  
  DOI: 10.1016/j.str.2024.02.007
  
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sciencedirect.com/science/article/pii/S0969212624000467
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Generation of heterozygous (MCRIi030-A-1) and homozygous (MCRIi030-A-2) NR2F2/COUP-TFII knockout human iPSC lines

2
1. scibot 05 Mar 2024
  
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  RRID:AB_2636929
  
  DOI: 10.1016/j.scr.2024.103374
  
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Brazilin is a natural product inhibitor of the NLRP3 inflammasome

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EXO1 protects BRCA1-deficient cells against toxic DNA lesions

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The phosphodiesterase 2A controls lymphatic junctional maturation via cGMP-dependent notch signaling

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Proteogenomic characterization of small cell lung cancer identifies biological insights and subtype-specific therapeutic strategies

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Tumor-immune microenvironment and NRF2 associate with clinical efficacy of PD-1 blockade combined with chemotherapy in lung squamous cell carcinoma

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Soluble epoxide hydrolase maintains steady-state lipid turnover linked with autocrine signaling in peritoneal macrophages

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Identification of IQCH as a calmodulin-associated protein required for sperm motility in humans

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The Prc and CtpA proteases modulate cell-surface signaling activity and virulence in Pseudomonas aeruginosa

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Phosphorylation by ATR triggers FANCD2 chromatin loading and activates the Fanconi anemia pathway

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Galectin-1 induces a tumor-associated macrophage phenotype and upregulates indoleamine 2,3-dioxygenase-1

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Discovery of an inhibitor of DNA-driven inflammation that preferentially targets the AIM2 inflammasome

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Broad immunity to SARS-CoV-2 variants of concern mediated by a SARS-CoV-2 receptor-binding domain protein vaccine

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Neuronal blockade of thyroid hormone signaling increases sensitivity to diet-induced obesity in adult male mice

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Pathological variants in TOP3A cause distinct disorders of mitochondrial and nuclear genome stability

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Jan 2023
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Fast and efficient synaptosome isolation and post-synaptic density enrichment from hiPSC-motor neurons by biochemical sub-cellular fractionation

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SSX addiction in melanoma propagates tumor growth and metastasis

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Targeting histone methylation to reprogram the transcriptional state that drives survival of drug-tolerant myeloid leukemia persisters

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A genetically modified minipig model for Alzheimer’s disease with SORL1 haploinsufficiency

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The human mitochondrial genome contains a second light strand promoter

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Inhibition of mutant IDH1 promotes cycling of acute myeloid leukemia stem cells

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Sortilin Modulates Schwann Cell Signaling and Remak Bundle Regeneration Following Nerve Injury

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C/EBPδ-induced epigenetic changes control the dynamic gene transcription of S100a8 and S100a9

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Characterization and functional interrogation of the SARS-CoV-2 RNA interactome

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DNA replication is highly resilient and persistent under the challenge of mild replication stress

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Protein-lipid interaction at low pH induces oligomerization of the MakA cytotoxin from Vibrio cholerae

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Proteogenomic characterization identifies clinically relevant subgroups of intrahepatic cholangiocarcinoma

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Mitochondrial metabolism coordinates stage-specific repair processes in macrophages during wound healing

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Loss of nuclear DNA ligase III reverts PARP inhibitor resistance in BRCA1/53BP1 double-deficient cells by exposing ssDNA gaps

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Establishment of a second generation homozygous CRISPRa human induced pluripotent stem cell (hiPSC) line for enhanced levels of endogenous gene activation

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NOTCH3 variant position is associated with NOTCH3 aggregation load in CADASIL vasculature

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Untitled document

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Untitled document

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Untitled document

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VAP‐SCRN1 interaction regulates dynamic endoplasmic reticulum remodeling and presynaptic function

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  anti‐mouse anti‐HRP
  
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Establishment of two homozygous CRISPR interference (CRISPRi) knock-in human induced pluripotent stem cell (hiPSC) lines for titratable endogenous gene repression

1
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  RRID:AB_2636929
  
  DOI: 10.1016/j.scr.2021.102473
  
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Wnt signaling reprograms metabolism in dental pulp stem cells

1
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  DOI: 10.1002/jcp.27977
  
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Dynamic Palmitoylation Targets MAP6 to the Axon to Promote Microtubule Stabilization during Neuronal Polarization

2
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  AB_2636929
  
  DOI: 10.1016/j.neuron.2017.04.042
  
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  DOI: 10.1016/j.neuron.2017.04.042
  
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Untitled document

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Shank Proteins Couple the Endocytic Zone to the Postsynaptic Density to Control Trafficking and Signaling of Metabotropic Glutamate Receptor 5

1
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An mTORC1-GRASP55 signaling axis controls unconventional secretion to reshape the extracellular proteome upon stress

1
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  DOI: 10.1016/j.molcel.2021.06.017
  
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Suppression of β-catenin signaling in colon carcinoma cells by a bacterial protein

1
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  rabbit anti-mouse HRP-conjugated IgG
  
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The PP2A-Integrator-CDK9 axis fine-tunes transcription and can be targeted therapeutically in cancer

1
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  DOI: 10.1016/j.cell.2021.04.022
  
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RhoA/Cdc42 signaling drives cytoplasmic maturation but not endomitosis in megakaryocytes

1
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  DOI: 10.1016/j.celrep.2021.109102
  
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The USP7-TRIM27 axis mediates non-canonical PRC1.1 function and is a druggable target in leukemia

1
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  DOI: 10.1016/j.isci.2021.102435
  
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cell.com/iscience/abstract/S2589-0042(21)00403-X
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Central Ceramide Signaling Mediates Obesity-Induced Precocious Puberty

1
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  DOI: 10.1016/j.cmet.2020.10.001
  
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Local production of lactate, ribose phosphate, and amino acids by human triple-negative breast cancer

1
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PRMT6 methylation of RCC1 regulates mitosis, tumorigenicity, and radiation response of glioblastoma stem cells

1
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  DOI: 10.1016/j.molcel.2021.01.015
  
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Multi-color Molecular Visualization of Signaling Proteins Reveals How C-Terminal Src Kinase Nanoclusters Regulate T Cell Receptor Activation

1
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BPS Publications

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  RRID:AB_2636929
  
  DOI: 10.1111/bph.15275
  
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elifesciences.org elifesciences.org

LRRC8A is essential for hypotonicity-, but not for DAMP-induced NLRP3 inflammasome activation

1
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  DOI: 10.7554/eLife.59704
  
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Oct 2020
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Phosphorylation of eIF2α promotes Schwann cell differentiation and myelination in CMT1B mice with activated UPR

1
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  DOI: 10.1523/JNEUROSCI.0957-20.2020
  
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jneurosci.org/content/40/42/8174
Sep 2020
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Repression of Transcription at DNA Breaks Requires Cohesin throughout Interphase and Prevents Genome Instability

1
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  DOI: 10.1016/j.molcel.2018.11.001
  
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Non-canonical Caspase-1 Signaling Drives RIP2-Dependent and TNF-α-Mediated Inflammation In Vivo

1
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Structure of the TSC2 GAP Domain: Mechanistic Insight into Catalysis and Pathogenic Mutations

1
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  DOI: 10.1016/j.str.2020.05.008
  
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Probiotic Bacillus subtilis Protects against α-Synuclein Aggregation in C. elegans

1
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  DOI: 10.1016/j.celrep.2019.12.078
  
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Essential Functions of Glycans in Human Epithelia Dissected by a CRISPR-Cas9-Engineered Human Organotypic Skin Model

1
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CRISPR-Based Adenine Editors Correct Nonsense Mutations in a Cystic Fibrosis Organoid Biobank

1
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  DOI: 10.1016/j.stem.2020.01.019
  
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Generation of homozygous CRISPRa human induced pluripotent stem cell (hiPSC) lines for sustained endogenous gene activation

1
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  DOI: 10.1016/j.scr.2020.101944
  
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Bladder cancer therapy without toxicity ‐ A dose‐escalation study of alpha1‐oleate

1
1. scibot 03 Sep 2020
  
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  polyclonal rabbit anti‐mouse IgG‐HRP
  
  DOI: 10.1002/ijc.33019
  
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Modeling of Cisplatin-Induced Signaling Dynamics in Triple-Negative Breast Cancer Cells Reveals Mediators of Sensitivity

1
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  DOI: 10.1016/j.celrep.2019.07.070
  
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IKKα Kinase Regulates the DNA Damage Response and Drives Chemo-resistance in Cancer

1
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  DOI: 10.1016/j.molcel.2019.05.036
  
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Phosphorylation of FANCD2 Inhibits the FANCD2/FANCI Complex and Suppresses the Fanconi Anemia Pathway in the Absence of DNA Damage

1
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Integrated Proteogenomic Characterization of HBV-Related Hepatocellular Carcinoma

1
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  DOI: 10.1016/j.cell.2019.08.052
  
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Untitled document

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  DOI: 10.1016/j.molcel.2018.11.001
  
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Untitled document

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  DOI: 10.1016/j.str.2018.12.002
  
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sciencedirect.com/science/article/pii/S0969212618304581
Nov 2018
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Untitled document

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Cytosolic Aspartate Availability Determines Cell Survival When Glutamine Is Limiting

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Sustained Expression of Negative Regulators of Myelination Protects Schwann Cells from Dysmyelination in a Charcot–Marie–Tooth 1B Mouse Model

1
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jneurosci.org/content/38/18/4275
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Selective Loss of PARG Restores PARylation and Counteracts PARP Inhibitor-Mediated Synthetic Lethality

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1. scibot 05 Nov 2018
  
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  RRID:AB_2636929
  
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sciencedirect.com/science/article/pii/S1535610818302228
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LKB1, Salt-Inducible Kinases, and MEF2C Are Linked Dependencies in Acute Myeloid Leukemia

1
1. scibot 05 Nov 2018
  
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  Curator: @Jmenke
  
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sciencedirect.com/science/article/pii/S1097276518301096
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A Method for the Acute and Rapid Degradation of Endogenous Proteins

2
1. scibot 05 Nov 2018
  
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  RRID:AB_2636929
  
  Curator: @evieth
  
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2. scibot 05 Nov 2018
  
  in Public
  
  RRID:AB_2636929
  
  Curator: @evieth
  
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  (Dako Cat# P0260, RRID:AB_2636929)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5733393/
Nov 2017
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Enhancer Reprogramming Promotes Pancreatic Cancer Metastasis

1
1. scibot 08 Nov 2017
  
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  RRID:AB_2636929
  
  Curator: @chewbeccax
  
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  (Dako Cat# P0260, RRID:AB_2636929)
  
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sciencedirect.com/science/article/pii/S0092867417308140

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