49 Matching Annotations
  1. Apr 2024
  2. www.sciencedirect.com www.sciencedirect.com
    IFNα-induced BST2+ tumor-associated macrophages facilitate immunosuppression and tumor growth in pancreatic cancer by ERK-CXCL7 signaling
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    1. scibot 11 Apr 2024
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    sciencedirect.com/science/article/pii/S2211124724004169
  3. Mar 2024
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The effects of Aurora Kinase inhibition on thyroid cancer growth and sensitivity to MAPK-directed therapies
    1
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      DOI: 10.1080/15384047.2024.2332000

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    ncbi.nlm.nih.gov/pmc/articles/PMC10962586/
  5. Feb 2024
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Stromal-derived MAOB promotes prostate cancer growth and progression
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    ncbi.nlm.nih.gov/pmc/articles/PMC10857382/
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitochondrial-encoded complex I impairment induces a targetable dependency on aerobic fermentation in Hürthle cell carcinoma of the thyroid
    1
    1. scibot 06 Feb 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC10524862/
  8. Jan 2024
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    Cholinergic signaling via muscarinic M1 receptor confers resistance to docetaxel in prostate cancer
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      DOI: 10.1016/j.xcrm.2023.101388

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    sciencedirect.com/science/article/pii/S2666379123006171
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    Antitumor efficacy of a sequence-specific DNA-targeted γPNA-based c-Myc inhibitor
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      DOI: 10.1016/j.xcrm.2023.101354

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    sciencedirect.com/science/article/pii/S2666379123005712
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    Metabolic switch regulates lineage plasticity and induces synthetic lethality in triple-negative breast cancer
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    sciencedirect.com/science/article/pii/S1550413123004552
  12. Nov 2023
  13. link.springer.com link.springer.com
    Aloperine targets lysosomes to inhibit late autophagy and induces cell death through apoptosis and paraptosis in glioblastoma
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    1. scibot 25 Nov 2023
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      DOI: 10.1186/s43556-023-00155-x

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    link.springer.com/article/10.1186/s43556-023-00155-x
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    Single-cell transcriptomics identifies a WNT7A-FZD5 signaling axis that maintains fallopian tube stem cells in patient-derived organoids
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    1. scibot 03 Nov 2023
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      DOI: 10.1016/j.celrep.2023.113354

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    sciencedirect.com/science/article/pii/S2211124723013669
  15. Aug 2023
  16. dx.doi.org dx.doi.org
    Vincristine Enhances the Efficacy of MEK Inhibitors in Preclinical Models of KRAS-mutant Colorectal Cancer
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    dx.doi.org/10.1158/1535-7163.MCT-23-0110
  17. Jun 2023
  18. www.sciencedirect.com www.sciencedirect.com
    Ferroptosis surveillance independent of GPX4 and differentially regulated by sex hormones
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    1. scibot 02 Jun 2023
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    sciencedirect.com/science/article/pii/S0092867423005226
  19. May 2023
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    A Wnt-induced lncRNA-DGCR5 splicing switch drives tumor-promoting inflammation in esophageal squamous cell carcinoma
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    1. scibot 25 May 2023
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      DOI: 10.1016/j.celrep.2023.112542

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    sciencedirect.com/science/article/pii/S2211124723005533
  21. Apr 2023
  22. www.sciencedirect.com www.sciencedirect.com
    CDK5-PRMT1-WDR24 signaling cascade promotes mTORC1 signaling and tumor growth
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    1. scibot 06 Apr 2023
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      DOI: 10.1016/j.celrep.2023.112316

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    sciencedirect.com/science/article/pii/S2211124723003273
  23. Jan 2023
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MOZ and Menin-MLL Complexes are Complementary Regulators of Chromatin Association and Transcriptional Output in Gastrointestinal Stromal Tumor
    1
    1. scibot 07 Jan 2023
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      DOI: 10.1158/2159-8290.CD-21-0646

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    ncbi.nlm.nih.gov/pmc/articles/PMC9453853/
  25. Dec 2022
  26. www.sciencedirect.com www.sciencedirect.com
    PALI1 promotes tumor growth through competitive recruitment of PRC2 to G9A-target chromatin for dual epigenetic silencing
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      DOI: 10.1016/j.molcel.2022.11.010

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    sciencedirect.com/science/article/pii/S1097276522010991
  27. Oct 2022
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Novel NF2 Splicing Mutant Causes Neurofibromatosis Type 2 via Liquid-liquid Phase Separation with LATS and Hippo Pathway.
    1
    1. scibot 27 Oct 2022
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      DOI: 10.1016/j.isci.2022.105275

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    ncbi.nlm.nih.gov/pmc/articles/PMC9589172/
  29. www.sciencedirect.com www.sciencedirect.com
    Destabilization of TP53 by USP10 is essential for neonatal autophagy and survival
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    sciencedirect.com/science/article/pii/S2211124722012761
  30. Jun 2022
  31. 52.53.155.43 52.53.155.43
    cd-21-0646-html.html
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    1. scibot 30 Jun 2022
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    52.53.155.43/8eb6598be53599407b5cdbf0aa5958efcfba5063/cd-21-0646 (2)-html.html
  32. aacrjournals.org aacrjournals.org
    Preclinical modeling of leiomyosarcoma identifies susceptibility to transcriptional CDK inhibitors through antagonism of E2F-driven oncogenic gene expression.
    1
    1. scibot 14 Jun 2022
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      DOI: 10.1158/1078-0432.CCR-21-3523

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    aacrjournals.org/clincancerres/article/28/11/2397/698931/Preclinical-Modeling-of-Leiomyosarcoma-Identifies
  33. Feb 2022
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bidirectional Crosstalk between MAOA and AR Promotes Hormone-Dependent and Castration-Resistant Prostate Cancer
    1
    1. scibot 16 Feb 2022
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      DOI: 10.1158/0008-5472.CAN-21-0198

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    ncbi.nlm.nih.gov/pmc/articles/PMC8373824/
  35. Jan 2022
  36. journals.sagepub.com journals.sagepub.com
    Complex Tumor Spheroids, a Tissue-Mimicking Tumor Model, for Drug Discovery and Precision Medicine - Gurmeet Kaur, David M. Evans, Beverly A. Teicher, Nathan P. Coussens, 2021
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    journals.sagepub.com/doi/full/10.1177/24725552211038362
  37. Dec 2021
  38. journals.sagepub.com journals.sagepub.com
    Complex Tumor Spheroids, a Tissue-Mimicking Tumor Model, for Drug Discovery and Precision Medicine - Gurmeet Kaur, David M. Evans, Beverly A. Teicher, Nathan P. Coussens, 2021
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    journals.sagepub.com/doi/full/10.1177/24725552211038362
  39. www.nature.com www.nature.com
    A targetable LIFR−NF-κB−LCN2 axis controls liver tumorigenesis and vulnerability to ferroptosis
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      DOI: 10.1038/s41467-021-27452-9

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    nature.com/articles/s41467-021-27452-9
  40. Nov 2021
  41. journals.sagepub.com journals.sagepub.com
    Complex Tumor Spheroids, a Tissue-Mimicking Tumor Model, for Drug Discovery and Precision Medicine - Gurmeet Kaur, David M. Evans, Beverly A. Teicher, Nathan P. Coussens, 2021
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  42. www.sciencedirect.com www.sciencedirect.com
    RNA-binding protein FXR1 drives cMYC translation by recruiting eIF4F complex to the translation start site
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      DOI: 10.1016/j.celrep.2021.109934

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    sciencedirect.com/science/article/pii/S2211124721014078
  43. Oct 2021
  44. academic.oup.com academic.oup.com
    Hsa_circ_0023990 promotes tumor growth and glycolysis in dedifferentiated TC via targeting miR-485-5p/FOXM1 axis
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      DOI: 10.1210/endocr/bqab172

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    academic.oup.com/endo/article/162/12/bqab172/6355332
  45. www.sciencedirect.com www.sciencedirect.com
    Charting oncogenicity of genes and variants across lineages via multiplexed screens in teratomas
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      DOI: 10.1016/j.isci.2021.103149

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    sciencedirect.com/science/article/pii/S2589004221011172
  46. Aug 2021
  47. academic.oup.com academic.oup.com
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    academic.oup.com/endo/article/158/7/2309/3605334
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    ncbi.nlm.nih.gov/pmc/articles/PMC5505221/
  49. Jul 2021
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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      DOI: 10.1016/j.celrep.2018.11.035

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    ncbi.nlm.nih.gov/pmc/articles/PMC6342284/
  51. www.sciencedirect.com www.sciencedirect.com
    Inhibition of LTA4H by bestatin in human and mouse colorectal cancer
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      DOI: 10.1016/j.ebiom.2019.05.008

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    sciencedirect.com/science/article/pii/S2352396419303093
  52. www.sciencedirect.com www.sciencedirect.com
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    sciencedirect.com/science/article/pii/S2211124718317984
  53. Jun 2021
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    KEAP1 deficiency drives glucose dependency and sensitizes lung cancer cells and tumors to GLUT inhibition
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      DOI: 10.1016/j.isci.2021.102649

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    ncbi.nlm.nih.gov/pmc/articles/PMC8193145/
  55. Apr 2021
  56. www.sciencedirect.com www.sciencedirect.com
    Commitment and oncogene-induced plasticity of human stem cell-derived pancreatic acinar and ductal organoids
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    sciencedirect.com/science/article/pii/S1934590921001557
  57. Feb 2021
  58. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Inhibition of BRAF and ERK1/2 has synergistic effects on thyroid cancer growth in vitro and in vivo
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      DOI: 10.1002/mc.23284

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    onlinelibrary.wiley.com/doi/full/10.1002/mc.23284
  59. Oct 2020
  60. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Enhancer Reprogramming Confers Dependence on Glycolysis and IGF Signaling in KMT2D Mutant Melanoma
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      DOI: 10.1016/j.celrep.2020.108293

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    pubmed.ncbi.nlm.nih.gov/33086062/
  61. Sep 2020
  62. www.sciencedirect.com www.sciencedirect.com
    KMT2D Deficiency Impairs Super-Enhancers to Confer a Glycolytic Vulnerability in Lung Cancer
    1
    1. scibot 17 Sep 2020
      RRID:AB_2636984

      DOI: 10.1016/j.ccell.2020.03.005

      Resource: (Cell Signaling Technology Cat# 9027, RRID:AB_2636984)

      Curator: @ethanbadger

      SciCrunch record: RRID:AB_2636984

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      RRID:AB_2636984 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1535610820301069
  63. cancerres.aacrjournals.org cancerres.aacrjournals.org
    A Novel Bioengineered MicroRNA-127 Prodrug Suppresses The Growth And Metastatic Potential Of Triple Negative Breast Cancer Cells
    1
    1. scibot 04 Sep 2020
      Cell Signaling Technology, catalog no. 9027

      DOI: 10.1158/0008-5472.CAN-19-0656

      Resource: (Cell Signaling Technology Cat# 9027, RRID:AB_2636984)

      Curator: @Naa003

      SciCrunch record: RRID:AB_2636984

      Curator comments: Ki-67 (D2H10) Rabbit mAb (IHC Specific) antibody Cell Signaling Technology Cat# 9027

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      RRID:AB_2636984 RRIDCUR:Missing
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    cancerres.aacrjournals.org/content/80/3/418
  64. Jan 2020
  65. www.cell.com www.cell.com
    miRNA551b-3p Activates an Oncostatin Signaling Module for the Progression of Triple-Negative Breast Cancer
    1
    1. scibot 13 Jan 2020
      RRID:AB_2636984

      DOI: 10.1016/j.celrep.2019.11.085

      Resource: (Cell Signaling Technology Cat# 9027, RRID:AB_2636984)

      Curator: @ethanbadger

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      RRID:AB_2636984 RRIDCUR:Validated
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    cell.com/cell-reports/fulltext/S2211-1247(19)31576-1
  66. www.sciencedirect.com www.sciencedirect.com
    A Novel Allosteric Inhibitor of Phosphoglycerate Mutase 1 Suppresses Growth and Metastasis of Non-Small-Cell Lung Cancer
    1
    1. scibot 13 Jan 2020
      RRID:AB_2636984

      DOI: 10.1016/j.cmet.2019.09.014

      Resource: (Cell Signaling Technology Cat# 9027, RRID:AB_2636984)

      Curator: @ethanbadger

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      RRID:AB_2636984 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1550413119305170
  67. Nov 2018
  68. www.sciencedirect.com www.sciencedirect.com
    CD10+GPR77+ Cancer-Associated Fibroblasts Promote Cancer Formation and Chemoresistance by Sustaining Cancer Stemness
    1
    1. scibot 05 Nov 2018
      RRID:AB_2636984

      Curator: @Jmenke

      Resource used:

      (Cell Signaling Technology Cat# 9027, RRID:AB_2636984)

      SciCrunch record: RRID:AB_2636984

      Alternate resolvers: SciCrunch xml N2T identifiers.org

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      RRID:AB_2636984 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S0092867418300448
  69. Nov 2017
  70. www.sciencedirect.com www.sciencedirect.com
    In Vivo Amelioration of Age-Associated Hallmarks by Partial Reprogramming
    1
    1. scibot 08 Nov 2017
      9027

      Curator: @Jmenke

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      (Cell Signaling Technology Cat# 9027, RRID:AB_2636984)

      SciCrunch record: RRID:AB_2636984

      Alternate resolvers: SciCrunch xml N2T identifiers.org

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      RRID:AB_2636984 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S0092867416316646
  71. www.sciencedirect.com www.sciencedirect.com
    Stabilization of the c-Myc Protein by CAMKIIγ Promotes T Cell Lymphoma
    1
    1. scibot 08 Nov 2017
      AB_2636984

      Curator: @chewbeccax

      Curator note: v

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      (Cell Signaling Technology Cat# 9027, RRID:AB_2636984)

      SciCrunch record: RRID:AB_2636984

      Alternate resolvers: SciCrunch xml N2T identifiers.org

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      RRID:AB_2636984 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1535610817302519
  72. academic.oup.com academic.oup.com
    IGF1R Expression in Ovarian Granulosa Cells is Essential for Steroidogenesis, Follicle Survival, and Fertility in Female Mice
    1
    1. scibot 08 Nov 2017
      AB_2636984 

      Curator: @chewbeccax

      Resource used:

      (Cell Signaling Technology Cat# 9027, RRID:AB_2636984)

      SciCrunch record: RRID:AB_2636984

      Alternate resolvers: SciCrunch xml N2T identifiers.org

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      RRID:AB_2636984
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    academic.oup.com/endo/article/158/7/2309/3605334/IGF1R-Expression-in-Ovarian-Granulosa-Cells-Is