Hypothesis

32 Matching Annotations

Mar 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Distinct signaling mechanisms and proteome phenotypes are elicited by compartment-specific genetic defects of copper homeostasis

1
1. scibot 28 Mar 2026
  
  in Public
  
  AB_2636990
  
  DOI: 10.64898/2026.01.13.699066
  
  Resource: (Cell Signaling Technology Cat# 12829, RRID:AB_2636990)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2636990
  
  What is this?
  
  RRID:AB_2636990
Visit annotations in context

Tags

RRID:AB_2636990

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12871135/
Feb 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Unraveling Network Pharmacology‐Based Therapeutics of Anthranilate Sulfonamides via Sirtuins/FOXO3a Cascade in Alzheimer's Disease

1
1. scibot 24 Feb 2026
  
  in Public
  
  RRID:AB_2636990
  
  DOI: 10.1111/jnc.70377
  
  Resource: (Cell Signaling Technology Cat# 12829, RRID:AB_2636990)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2636990
  
  What is this?
  
  RRID:AB_2636990
Visit annotations in context

Tags

RRID:AB_2636990

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12920268/
Dec 2025
www.sciencedirect.com:5037 www.sciencedirect.com:5037

Lung adenocarcinoma surfaceome remodeling with EGFR inhibitors uncovers placental alkaline phosphatase as a target for combination therapy

1
1. scibot 17 Dec 2025
  
  in Public
  
  RRID:AB_2636990
  
  DOI: 10.1016/j.xcrm.2025.102513
  
  Resource: (Cell Signaling Technology Cat# 12829, RRID:AB_2636990)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2636990
  
  What is this?
  
  RRID:AB_2636990
Visit annotations in context

Tags

RRID:AB_2636990

Annotators

scibot

URL

sciencedirect.com:5037/science/article/pii/S2666379125005865
Jul 2025
www.sciencedirect.com www.sciencedirect.com

β-catenin functions as a molecular adapter for disordered cBAF interactions

1
1. scibot 22 Jul 2025
  
  in Public
  
  RRID:AB_2636990
  
  DOI: 10.1016/j.molcel.2025.06.026
  
  Resource: (Cell Signaling Technology Cat# 12829, RRID:AB_2636990)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2636990
  
  What is this?
  
  RRID:AB_2636990
Visit annotations in context

Tags

RRID:AB_2636990

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1097276525005763
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The XPO1 inhibitor Eltanexor modulates the Wnt/β-catenin signaling pathway to reduce colorectal cancer tumorigenesis

2
1. scibot 17 Jul 2025
  
  in Public
  
  AB_2636990
  
  DOI: 10.1158/2767-9764.CRC-25-0052
  
  Resource: (Cell Signaling Technology Cat# 12829, RRID:AB_2636990)
  
  Curator: @sonofthor
  
  SciCrunch record: RRID:AB_2636990
  
  What is this?
  
  RRID:AB_2636990
2. scibot 17 Jul 2025
  
  in Public
  
  AB_2636990
  
  DOI: 10.1158/2767-9764.CRC-25-0052
  
  Resource: (Cell Signaling Technology Cat# 12829, RRID:AB_2636990)
  
  Curator: @sonofthor
  
  SciCrunch record: RRID:AB_2636990
  
  What is this?
  
  RRID:AB_2636990
Visit annotations in context

Tags

RRID:AB_2636990

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12260813/
Jun 2025
journals.sagepub.com journals.sagepub.com

Holothurian Glycosaminoglycan (hGAG) Promoted Bim-Induced Apoptosis in Human Lung Adenocarcinoma A549 Cell Line Through Inhibition of Akt-Mediated FOXO3a Translocation

1
1. scibot 21 Jun 2025
  
  in Public
  
  AB_2636990
  
  DOI: 10.1177/15347354251341442
  
  Resource: (Cell Signaling Technology Cat# 12829, RRID:AB_2636990)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2636990
  
  What is this?
  
  RRID:AB_2636990
Visit annotations in context

Tags

RRID:AB_2636990

Annotators

scibot

URL

journals.sagepub.com/doi/full/10.1177/15347354251341442
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Holothurian Glycosaminoglycan (hGAG) Promoted Bim-Induced Apoptosis in Human Lung Adenocarcinoma A549 Cell Line Through Inhibition of Akt-Mediated FOXO3a Translocation

1
1. scibot 12 Jun 2025
  
  in Public
  
  AB_2636990
  
  DOI: 10.1177/15347354251341442
  
  Resource: (Cell Signaling Technology Cat# 12829, RRID:AB_2636990)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2636990
  
  What is this?
  
  RRID:AB_2636990
Visit annotations in context

Tags

RRID:AB_2636990

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12144356/
Jul 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

KIT in oocytes: a key factor for oocyte survival and reproductive lifespan

1
1. scibot 27 Jul 2024
  
  in Public
  
  RRID:AB_2636990
  
  DOI: 10.1016/j.ebiom.2024.105263
  
  Resource: (Cell Signaling Technology Cat# 12829, RRID:AB_2636990)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2636990
  
  What is this?
  
  RRID:AB_2636990
Visit annotations in context

Tags

RRID:AB_2636990

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC11338130/
www.sciencedirect.com www.sciencedirect.com

DNA damage-mediated FTO downregulation promotes CRPC progression by inhibiting FOXO3a via an m6A-dependent mechanism

1
1. scibot 26 Jul 2024
  
  in Public
  
  AB_2636990
  
  DOI: 10.1016/j.isci.2024.110505
  
  Resource: (Cell Signaling Technology Cat# 12829, RRID:AB_2636990)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2636990
  
  What is this?
  
  RRID:AB_2636990
Visit annotations in context

Tags

RRID:AB_2636990

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2589004224017309
Mar 2024
www.futuremedicine.com www.futuremedicine.com

Epigenetic disruption of histone deacetylase-2 accelerated apoptotic signaling and retarded malignancy in gastric cells

1
1. scibot 30 Mar 2024
  
  in Public
  
  RRID: AB_2636990
  
  DOI: 10.2217/epi-2023-0350
  
  Resource: (Cell Signaling Technology Cat# 12829, RRID:AB_2636990)
  
  Curator: @AniH
  
  SciCrunch record: RRID:AB_2636990
  
  What is this?
  
  RRID:AB_2636990
Visit annotations in context

Tags

RRID:AB_2636990

Annotators

scibot

URL

futuremedicine.com/doi/10.2217/epi-2023-0350
Oct 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

ONC201/TIC10 enhances durability of mTOR inhibitor everolimus in metastatic ER+ breast cancer

1
1. scibot 05 Oct 2023
  
  in Public
  
  RRID:AB_2636990
  
  DOI: 10.7554/eLife.85898
  
  Resource: (Cell Signaling Technology Cat# 12829, RRID:AB_2636990)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2636990
  
  What is this?
  
  RRID:AB_2636990
Visit annotations in context

Tags

RRID:AB_2636990

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10541180/
Sep 2022
www.sciencedirect.com www.sciencedirect.com

The CX3CL1 intracellular domain exhibits neuroprotection via insulin receptor/ insulin like growth factor receptor signaling

1
1. scibot 27 Sep 2022
  
  in Public
  
  RRID:AB_2636990
  
  DOI: 10.1016/j.jbc.2022.102532
  
  Resource: (Cell Signaling Technology Cat# 12829, RRID:AB_2636990)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2636990
  
  What is this?
  
  RRID:AB_2636990
Visit annotations in context

Tags

RRID:AB_2636990

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0021925822009759
Aug 2022
www.sciencedirect.com www.sciencedirect.com

Phosphoproteomics of primary AML patient samples reveals rationale for AKT combination therapy and p53 context to overcome selinexor resistance

1
1. scibot 10 Aug 2022
  
  in Public
  
  RRID:AB_2636990
  
  DOI: 10.1016/j.celrep.2022.111177
  
  Resource: (Cell Signaling Technology Cat# 12829, RRID:AB_2636990)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2636990
  
  What is this?
  
  RRID:AB_2636990
Visit annotations in context

Tags

RRID:AB_2636990

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124722009901
Jul 2022
www.sciencedirect.com www.sciencedirect.com

Slc12a8 in the lateral hypothalamus maintains energy metabolism and skeletal muscle functions during aging

1
1. scibot 30 Jul 2022
  
  in Public
  
  RRID:AB_2636990
  
  DOI: 10.1016/j.celrep.2022.111131
  
  Resource: (Cell Signaling Technology Cat# 12829, RRID:AB_2636990)
  
  Curator: @sophiastull
  
  SciCrunch record: RRID:AB_2636990
  
  What is this?
  
  RRID:AB_2636990
Visit annotations in context

Tags

RRID:AB_2636990

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124722009378
Mar 2022
52.53.155.43 52.53.155.43

japplphysiol.00536.2021-html.html

1
1. scibot 03 Mar 2022
  
  in Public
  
  RRID:AB_2636990
  
  DOI: 10.1152/japplphysiol.00536.2021
  
  Resource: (Cell Signaling Technology Cat# 12829, RRID:AB_2636990)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2636990
  
  What is this?
  
  RRID:AB_2636990
Visit annotations in context

Tags

RRID:AB_2636990

Annotators

scibot

URL

52.53.155.43/29de5e7222342c85eeeb25aa2522e8bbef77b2f2/japplphysiol.00536.2021-html.html
Feb 2022
academic.oup.com academic.oup.com

FOXO transcription factors are required for normal somatotrope function and growth

1
1. scibot 01 Feb 2022
  
  in Public
  
  RRID:AB_2636990
  
  DOI: 10.1210/endocr/bqab263
  
  Resource: (Cell Signaling Technology Cat# 12829, RRID:AB_2636990)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2636990
  
  What is this?
  
  RRID:AB_2636990
Visit annotations in context

Tags

RRID:AB_2636990

Annotators

scibot

URL

academic.oup.com/endo/article/163/2/bqab263/6490941
Sep 2021
www.sciencedirect.com www.sciencedirect.com

KARATE: PKA-induced KRAS4B-RHOA-mTORC2 supercomplex phosphorylates AKT in insulin signaling and glucose homeostasis

1
1. scibot 22 Sep 2021
  
  in Public
  
  RRID:AB_2636990
  
  DOI: 10.1016/j.molcel.2021.09.001
  
  Resource: (Cell Signaling Technology Cat# 12829, RRID:AB_2636990)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2636990
  
  What is this?
  
  RRID:AB_2636990
Visit annotations in context

Tags

RRID:AB_2636990

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1097276521007358
Jul 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Structural plasticity of actin-spectrin membrane skeleton and functional role of actin and spectrin in axon degeneration

1
1. scibot 28 Jul 2021
  
  in Public
  
  RRID: AB_2636990
  
  DOI: 10.7554/eLife.38730
  
  Resource: (Cell Signaling Technology Cat# 12829, RRID:AB_2636990)
  
  Curator: @evieth
  
  SciCrunch record: RRID:AB_2636990
  
  What is this?
  
  RRID:AB_2636990 RRIDCUR:Unrecognized
Visit annotations in context

Tags

RRIDCUR:Unrecognized

RRID:AB_2636990

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC6494423/
Jun 2021
www.sciencedirect.com www.sciencedirect.com

Target identification for small-molecule discovery in the FOXO3a tumor-suppressor pathway using a biodiverse peptide library

1
1. scibot 10 Jun 2021
  
  in Public
  
  RRID:AB_2636990
  
  DOI: 10.1016/j.chembiol.2021.05.009
  
  Resource: (Cell Signaling Technology Cat# 12829, RRID:AB_2636990)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2636990
  
  What is this?
  
  RRID:AB_2636990
Visit annotations in context

Tags

RRID:AB_2636990

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2451945621002543
Apr 2021
www.sciencedirect.com www.sciencedirect.com

A Cell-Autonomous Signature of Dysregulated Protein Phosphorylation Underlies Muscle Insulin Resistance in Type 2 Diabetes

1
1. scibot 29 Apr 2021
  
  in Public
  
  RRID:AB_2636990
  
  DOI: 10.1016/j.cmet.2020.08.007
  
  Resource: (Cell Signaling Technology Cat# 12829, RRID:AB_2636990)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2636990
  
  What is this?
  
  RRID:AB_2636990
Visit annotations in context

Tags

RRID:AB_2636990

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1550413120304204
www.sciencedirect.com www.sciencedirect.com

SETD2 Restricts Prostate Cancer Metastasis by Integrating EZH2 and AMPK Signaling Pathways

1
1. scibot 17 Apr 2021
  
  in Public
  
  RRID:AB_2636990
  
  DOI: 10.1016/j.ccell.2020.05.022
  
  Resource: (Cell Signaling Technology Cat# 12829, RRID:AB_2636990)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2636990
  
  What is this?
  
  RRIDCUR:Validated RRID:AB_2636990
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_2636990

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1535610820302725
Sep 2020
onlinelibrary.wiley.com onlinelibrary.wiley.com

FOXO3a‐dependent Parkin regulates the development of gastric cancer by targeting ATP‐binding cassette transporter E1

1
1. scibot 17 Sep 2020
  
  in Public
  
  RRID:AB_2636990
  
  DOI: 10.1002/jcp.30040
  
  Resource: (Cell Signaling Technology Cat# 12829, RRID:AB_2636990)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2636990
  
  What is this?
  
  RRID:AB_2636990 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_2636990

Annotators

scibot

URL

onlinelibrary.wiley.com/doi/10.1002/jcp.30040
www.sciencedirect.com www.sciencedirect.com

Restraining Lysosomal Activity Preserves Hematopoietic Stem Cell Quiescence and Potency

1
1. scibot 17 Sep 2020
  
  in Public
  
  RRID:AB_2636990
  
  DOI: 10.1016/j.stem.2020.01.013
  
  Resource: (Cell Signaling Technology Cat# 12829, RRID:AB_2636990)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2636990
  
  What is this?
  
  RRID:AB_2636990 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_2636990

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1934590920300138
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

JNK signalling regulates antioxidant responses in neurons

1
1. scibot 15 Sep 2020
  
  in Public
  
  RRID:AB_2636990
  
  DOI: 10.1016/j.redox.2020.101712
  
  Resource: (Cell Signaling Technology Cat# 12829, RRID:AB_2636990)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2636990
  
  What is this?
  
  RRIDCUR:Validated RRID:AB_2636990
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_2636990

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC7502373/
www.sciencedirect.com www.sciencedirect.com

Low-Dose Vertical Inhibition of the RAF-MEK-ERK Cascade Causes Apoptotic Death of KRAS Mutant Cancers

1
1. scibot 10 Sep 2020
  
  in Public
  
  RRID:AB_2636990
  
  DOI: 10.1016/j.celrep.2020.107764
  
  Resource: (Cell Signaling Technology Cat# 12829, RRID:AB_2636990)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2636990
  
  What is this?
  
  RRID:AB_2636990 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_2636990

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124720307440
www.sciencedirect.com www.sciencedirect.com

Stromal Cell-Contact Dependent PI3K and APRIL Induced NF-κB Signaling Prevent Mitochondrial- and ER Stress Induced Death of Memory Plasma Cells

1
1. scibot 05 Sep 2020
  
  in Public
  
  RRID:AB_2636990
  
  DOI: 10.1016/j.celrep.2020.107982
  
  Resource: (Cell Signaling Technology Cat# 12829, RRID:AB_2636990)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2636990
  
  What is this?
  
  RRIDCUR:Validated RRID:AB_2636990
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_2636990

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124720309670
Jan 2020
www.sciencedirect.com www.sciencedirect.com

Mitohormesis Primes Tumor Invasion and Metastasis

1
1. scibot 12 Jan 2020
  
  in Public
  
  RRID:AB_2636990
  
  DOI: 10.1016/j.celrep.2019.04.095
  
  Resource: (Cell Signaling Technology Cat# 12829, RRID:AB_2636990)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2636990
  
  What is this?
  
  RRID:AB_2636990 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_2636990

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124719305753
www.sciencedirect.com www.sciencedirect.com

Lysosome Positioning Influences mTORC2 and AKT Signaling

1
1. scibot 12 Jan 2020
  
  in Public
  
  RRID:AB_2636990
  
  DOI: 10.1016/j.molcel.2019.05.009
  
  Resource: (Cell Signaling Technology Cat# 12829, RRID:AB_2636990)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2636990
  
  What is this?
  
  RRID:AB_2636990 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_2636990

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1097276519303624
Nov 2018
www.sciencedirect.com www.sciencedirect.com

FoxO Function Is Essential for Maintenance of Autophagic Flux and Neuronal Morphogenesis in Adult Neurogenesis

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:AB_2636990
  
  Curator: @Jmenke
  
  Resource used:
  
  (Cell Signaling Technology Cat# 12829, RRID:AB_2636990)
  
  SciCrunch record: RRID:AB_2636990
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:AB_2636990 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_2636990

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0896627318307207
Nov 2017
www.sciencedirect.com www.sciencedirect.com

Focal Adhesion- and IGF1R-Dependent Survival and Migratory Pathways Mediate Tumor Resistance to mTORC1/2 Inhibition

1
1. scibot 08 Nov 2017
  
  in Public
  
  RRID:AB_2636990
  
  Curator: @chewbeccax
  
  Resource used:
  
  (Cell Signaling Technology Cat# 12829, RRID:AB_2636990)
  
  SciCrunch record: RRID:AB_2636990
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:AB_2636990 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_2636990

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1097276517304914
www.sciencedirect.com www.sciencedirect.com

Integrin α7 Is a Functional Marker and Potential Therapeutic Target in Glioblastoma

1
1. scibot 08 Nov 2017
  
  in Public
  
  Rabbit monoclonal anti FoxO3aCell SignalingCat#12829
  
  Curator: @Jmenke
  
  Resource used:
  
  (Cell Signaling Technology Cat# 12829, RRID:AB_2636990)
  
  SciCrunch record: RRID:AB_2636990
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:AB_2636990 RRIDCUR:Missing
Visit annotations in context

Tags

RRIDCUR:Missing

RRID:AB_2636990

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1934590917301376