52 Matching Annotations
  1. Apr 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Generation of human alveolar epithelial type I cells from pluripotent stem cells
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    1. scibot 23 Apr 2024
      Cell Signaling TechnologyCat#13008

      DOI: 10.1016/j.stem.2024.03.017

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    sciencedirect.com/science/article/pii/S1934590924000985
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    NIBR-LTSi is a selective LATS kinase inhibitor activating YAP signaling and expanding tissue stem cells in vitro and in vivo
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    1. scibot 05 Apr 2024
      RRID:AB_2650553

      DOI: 10.1016/j.stem.2024.03.003

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    sciencedirect.com/science/article/pii/S1934590924000845
  4. Feb 2024
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Integrative modelling and analysis of signalling crosstalk reveal molecular switches coordinating YAP transcriptional activities
    1
    1. scibot 23 Feb 2024
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      DOI: 10.1016/j.isci.2024.109031

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    ncbi.nlm.nih.gov/pmc/articles/PMC10877689/
  6. 52.53.155.43 52.53.155.43
    YAP-mediated GPER signaling impedes proliferation and survival of prostate epithelium in benign prostatic hyperplasia
    1
    1. scibot 09 Feb 2024
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      DOI: 10.1016/j.isci.2024.109125

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    52.53.155.43/3b983d9532a50e2ebeba730d1190ef88722ceb9a/PIIS2589004224003468-html.html
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    YTHDF2-mediated circYAP1 drives immune escape and cancer progression through activating YAP1/TCF4-PD-L1 axis
    1
    1. scibot 01 Feb 2024
      RRID:AB_2650553

      DOI: 10.1016/j.isci.2023.108779

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    ncbi.nlm.nih.gov/pmc/articles/PMC10825049/
  8. Jan 2024
  9. www.sciencedirect.com www.sciencedirect.com
    Homology and the evolution of vocal folds in the novel avian voice box
    1
    1. scibot 10 Jan 2024
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      DOI: 10.1016/j.cub.2023.12.013

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    sciencedirect.com/science/article/pii/S0960982223016688
  10. Dec 2023
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    Epinephrine inhibits PI3Kα via the Hippo kinases
    1
    1. scibot 20 Dec 2023
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      DOI: 10.1016/j.celrep.2023.113535

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    sciencedirect.com/science/article/pii/S2211124723015474
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    Mitoguardin 1 and 2 promote granulosa cell proliferation by activating AKT and regulating the Hippo-YAP1 signaling pathway
    1
    1. scibot 01 Dec 2023
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      DOI: 10.1038/s41419-023-06312-y

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    ncbi.nlm.nih.gov/pmc/articles/PMC10682431/
  13. Oct 2023
  14. www.sciencedirect.com www.sciencedirect.com
    High-throughput chemogenetic drug screening reveals PKC-RhoA/PKN as a targetable signaling vulnerability in GNAQ-driven uveal melanoma
    1
    1. scibot 28 Oct 2023
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      DOI: 10.1016/j.xcrm.2023.101244

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    sciencedirect.com/science/article/pii/S2666379123004214
  15. Jul 2023
  16. www.nature.com www.nature.com
    MAP4Ks inhibition promotes retinal neuron regeneration from Müller glia in adult mice
    1
    1. scibot 14 Jul 2023
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      DOI: 10.1038/s41536-023-00310-6

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    nature.com/articles/s41536-023-00310-6
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IGF1R inhibition enhances the therapeutic effects of Gq/11 inhibition in metastatic uveal melanoma progression
    1
    1. scibot 06 Jul 2023
      RRID:AB_2650553

      DOI: 10.1158/1535-7163.MCT-22-0147

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    ncbi.nlm.nih.gov/pmc/articles/PMC9812929/
  18. Jun 2023
  19. www.sciencedirect.com www.sciencedirect.com
    TRIM21 is a druggable target for the treatment of metastatic colorectal cancer through ubiquitination and activation of MST2
    1
    1. scibot 24 Jun 2023
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      DOI: 10.1016/j.chembiol.2023.05.009

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    sciencedirect.com/science/article/pii/S2451945623001526
  20. May 2023
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Reprogramming of Iron Metabolism Confers Ferroptosis Resistance in ECM-Detached Cells
    1
    1. scibot 27 May 2023
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      DOI: 10.1016/j.isci.2023.106827

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    ncbi.nlm.nih.gov/pmc/articles/PMC10209538/
  22. www.sciencedirect.com www.sciencedirect.com
    LAPTM4B-YAP loop feedback amplification enhances the stemness of hepatocellular carcinoma
    1
    1. scibot 17 May 2023
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      DOI: 10.1016/j.isci.2023.106754

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    sciencedirect.com/science/article/pii/S2589004223008313
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    Extracellular vesicles in fatty liver promote a metastatic tumor microenvironment
    1
    1. scibot 12 May 2023
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    sciencedirect.com/science/article/pii/S1550413123001407
  24. Apr 2023
  25. www.sciencedirect.com www.sciencedirect.com
    Lysine long-chain fatty acylation regulates the TEAD transcription factor
    1
    1. scibot 15 Apr 2023
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      DOI: 10.1016/j.celrep.2023.112388

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    sciencedirect.com/science/article/pii/S2211124723003996
  26. Dec 2022
  27. www.sciencedirect.com www.sciencedirect.com
    YAP regulates the liver size during the fasting-refeeding transition in mice
    1
    1. scibot 24 Dec 2022
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      DOI: 10.1016/j.apsb.2022.12.011

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    sciencedirect.com/science/article/pii/S2211383522005196
  28. www.science.org www.science.org
    Cross-talk between TSC2 and the extracellular matrix controls pulmonary vascular proliferation and pulmonary hypertension
    1
    1. scibot 13 Dec 2022
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      DOI: 10.1126/scisignal.abn2743

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    science.org/doi/10.1126/scisignal.abn2743
  29. Nov 2022
  30. academic.oup.com academic.oup.com
    Effect of inactivation of Mst1 and Mst2 in the mouse adrenal cortex
    1
    1. scibot 19 Nov 2022
      RRID:AB_2650553

      DOI: 10.1210/jendso/bvac143

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    academic.oup.com/jes/article/7/1/bvac143/6702160
  31. Sep 2022
  32. www.sciencedirect.com www.sciencedirect.com
    A nuclear cAMP microdomain suppresses tumor growth by Hippo pathway inactivation
    1
    1. scibot 29 Sep 2022
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      DOI: 10.1016/j.celrep.2022.111412

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    sciencedirect.com/science/article/pii/S2211124722012530
  33. Jul 2022
  34. www.sciencedirect.com www.sciencedirect.com
    Poziotinib for EGFR exon 20-mutant NSCLC: Clinical efficacy, resistance mechanisms, and impact of insertion location on drug sensitivity
    1
    1. scibot 13 Jul 2022
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      DOI: 10.1016/j.ccell.2022.06.006

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    sciencedirect.com/science/article/pii/S1535610822002707
  35. Jun 2022
  36. 52.53.155.43 52.53.155.43
    mct-21-0848-html.html
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    1. scibot 30 Jun 2022
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      DOI: 10.1158/1535-7163.mct-21-0848

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    52.53.155.43/12e7b7b771463d8107a4061a3543e1c33fbd2829/mct-21-0848-html.html
  37. link.springer.com link.springer.com
    The granulosa cell response to luteinizing hormone is partly mediated by YAP1-dependent induction of amphiregulin
    1
    1. scibot 15 Jun 2022
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      DOI: 10.1186/s12964-022-00843-1

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    link.springer.com/article/10.1186/s12964-022-00843-1
  38. Mar 2022
  39. www.sciencedirect.com www.sciencedirect.com
    Counteractive and cooperative actions of muscle β-catenin and CaV1.1 during early neuromuscular synapse formation
    1
    1. scibot 24 Mar 2022
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      DOI: 10.1016/j.isci.2022.104025

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    sciencedirect.com/science/article/pii/S2589004222002954
  40. academic.oup.com academic.oup.com
    Mst1/2 is necessary for satellite cell differentiation to promote muscle regeneration
    1
    1. scibot 02 Mar 2022
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      DOI: 10.1093/stmcls/sxab010

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    academic.oup.com/stmcls/advance-article/doi/10.1093/stmcls/sxab010/6511691
  41. Feb 2022
  42. www.sciencedirect.com www.sciencedirect.com
    Substrate rigidity dictates colorectal tumorigenic cell stemness and metastasis via CRAD-dependent mechanotransduction
    1
    1. scibot 16 Feb 2022
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      DOI: 10.1016/j.celrep.2022.110390

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    sciencedirect.com/science/article/pii/S2211124722001115
  43. Oct 2021
  44. www.sciencedirect.com www.sciencedirect.com
    Renal Subcapsular Delivery of PGE2 Promotes Kidney Repair by Activating Endogenous Sox9+ Stem Cells
    1
    1. scibot 29 Oct 2021
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      DOI: 10.1016/j.isci.2021.103243

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    sciencedirect.com/science/article/pii/S2589004221012116
  45. www.sciencedirect.com www.sciencedirect.com
    Increased ACTL6A occupancy within mSWI/SNF chromatin remodelers drives human squamous cell carcinoma
    1
    1. scibot 23 Oct 2021
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      DOI: 10.1016/j.molcel.2021.10.005

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    sciencedirect.com/science/article/pii/S1097276521008340
  46. Sep 2021
  47. www.sciencedirect.com www.sciencedirect.com
    Senescent immune cells release grancalcin to promote skeletal aging
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      DOI: 10.1016/j.cmet.2021.08.009

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  48. Aug 2021
  49. www.sciencedirect.com www.sciencedirect.com
    Stabilization of Motin family proteins in NF2-deficient cells prevents full activation of YAP/TAZ and rapid tumorigenesis
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    1. scibot 25 Aug 2021
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      DOI: 10.1016/j.celrep.2021.109596

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    sciencedirect.com/science/article/pii/S2211124721010342
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    Exocyst protein subnetworks integrate Hippo and mTOR signaling to promote virus detection and cancer
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    1. scibot 04 Aug 2021
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      DOI: 10.1016/j.celrep.2021.109491

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    sciencedirect.com/science/article/pii/S2211124721009189
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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      DOI: 10.1016/j.celrep.2019.03.091

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    ncbi.nlm.nih.gov/pmc/articles/PMC6486488/
  52. Jun 2021
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Autophagy suppresses the formation of hepatocyte-derived cancer-initiating ductular progenitor cells in the liver
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    1. scibot 17 Jun 2021
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      DOI: 10.1126/sciadv.abf9141

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    ncbi.nlm.nih.gov/pmc/articles/PMC8177709/
  54. May 2021
  55. www.sciencedirect.com www.sciencedirect.com
    Cell size homeostasis is maintained by CDK4-dependent activation of p38 MAPK
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      DOI: 10.1016/j.devcel.2021.04.030

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    sciencedirect.com/science/article/pii/S1534580721003993
  56. journals.biologists.com journals.biologists.com
    Oxygen regulates epithelial stem cell proliferation via RhoA-actomyosin-YAP/TAZ signal in mouse incisor
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    1. scibot 10 May 2021
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      DOI: 10.1242/dev.194787

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    journals.biologists.com/dev/article/148/4/dev194787/223256/Oxygen-regulates-epithelial-stem-cell
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    The ZMYND8-regulated mevalonate pathway endows YAP-high intestinal cancer with metabolic vulnerability
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      DOI: 10.1016/j.molcel.2021.04.009

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    sciencedirect.com/science/article/pii/S1097276521003142
  58. Apr 2021
  59. www.sciencedirect.com www.sciencedirect.com
    Scribble sub-cellular localization modulates recruitment of YES1 to regulate YAP1 phosphorylation
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    1. scibot 28 Apr 2021
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      DOI: 10.1016/j.chembiol.2021.02.019

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    sciencedirect.com/science/article/pii/S2451945621001045
  60. Mar 2021
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    S1PR3–G12-biased agonist ALESIA targets cancer metabolism and promotes glucose starvation
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    1. scibot 29 Mar 2021
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      DOI: 10.1016/j.chembiol.2021.01.004

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    sciencedirect.com/science/article/pii/S2451945621000040
  62. Feb 2021
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    Constitutive androstane receptor induced-hepatomegaly is partially via yes-associated protein activation
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    1. scibot 27 Feb 2021
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      DOI: 10.1016/j.apsb.2020.11.021

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    sciencedirect.com/science/article/pii/S2211383520308182
  64. Dec 2020
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Actionable Cytopathogenic Host Responses of Human Alveolar Type 2 Cells to SARS-CoV-2
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    1. scibot 07 Dec 2020
      RRID:AB_2650553

      DOI: 10.1016/j.molcel.2020.11.028

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    ncbi.nlm.nih.gov/pmc/articles/PMC7674017/
  66. Sep 2020
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    Treatment-Induced Tumor Dormancy through YAP-Mediated Transcriptional Reprogramming of the Apoptotic Pathway
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      RRID:AB_2650553

      DOI: 10.1016/j.ccell.2019.12.006

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    sciencedirect.com/science/article/pii/S1535610819305768
  68. academic.oup.com academic.oup.com
    Targeted disruption of Lats1 and Lats2 in mice impairs adrenal cortex development and alters adrenocortical cell fate
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    1. scibot 14 Sep 2020
      RRID:AB_2650553

      DOI: 10.1210/endocr/bqaa052

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    Periostin Promotes Colorectal Tumorigenesis through Integrin-FAK-Src Pathway-Mediated YAP/TAZ Activation
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    1. scibot 04 Sep 2020
      RRID:AB_2650553

      DOI: 10.1016/j.celrep.2019.12.075

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    sciencedirect.com/science/article/pii/S2211124719317401
  70. Jan 2020
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    Kindlin-2 Inhibits the Hippo Signaling Pathway by Promoting Degradation of MOB1
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    1. scibot 13 Jan 2020
      RRID:AB_2650553

      DOI: 10.1016/j.celrep.2019.11.035

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    sciencedirect.com/science/article/pii/S2211124719315177
  72. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Sphingosine 1‐phosphate but not Fingolimod protects neurons against excitotoxic cell death by inducing neurotrophic gene expression in astrocytes
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    1. scibot 13 Jan 2020
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      DOI: 10.1111/jnc.14917

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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.14917
  73. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    1. scibot 13 Jan 2020
      RRID:AB_2650553

      DOI: 10.1111/bph.14674

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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.14674
  74. www.sciencedirect.com www.sciencedirect.com
    YAP/TAZ Activation Drives Uveal Melanoma Initiation and Progression
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    1. scibot 13 Jan 2020
      RRID:AB_2650553

      DOI: 10.1016/j.celrep.2019.03.021

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    sciencedirect.com/science/article/pii/S2211124719303286
  75. www.sciencedirect.com www.sciencedirect.com
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    1. scibot 13 Jan 2020
      RRID:AB_2650553

      DOI: 10.1016/j.celrep.2019.03.091

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    sciencedirect.com/science/article/pii/S2211124719304309
  76. www.sciencedirect.com www.sciencedirect.com
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    1. scibot 12 Jan 2020
      RRID:AB_2650553

      DOI: 10.1016/j.celrep.2019.01.076

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    sciencedirect.com/science/article/pii/S2211124719301056
  77. www.sciencedirect.com www.sciencedirect.com
    OTUB2 Promotes Cancer Metastasis via Hippo-Independent Activation of YAP and TAZ
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    1. scibot 12 Jan 2020
      RRID:AB_2650553

      DOI: 10.1016/j.molcel.2018.10.030

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    sciencedirect.com/science/article/pii/S1097276518308906
  78. Nov 2018
  79. www.sciencedirect.com www.sciencedirect.com
    Losmapimod Overcomes Gefitinib Resistance in Non-small Cell Lung Cancer by Preventing Tetraploidization
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    1. scibot 05 Nov 2018
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      Curator: @evieth

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    sciencedirect.com/science/article/pii/S2352396418300215
  80. Nov 2017
  81. www.sciencedirect.com www.sciencedirect.com
    An FAK-YAP-mTOR Signaling Axis Regulates Stem Cell-Based Tissue Renewal in Mice
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    1. scibot 08 Nov 2017
      13008

      Curator: @bandrow

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    sciencedirect.com/science/article/pii/S1934590917300942