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A self-amplifying nerve-fibroblast circuit drives colorectal cancer progression

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1. scibot 26 Jul 2026
  
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  DOI: 10.1016/j.ccell.2026.06.018
  
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sciencedirect.com/science/article/pii/S1535610826003053
Feb 2026
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A human patient-derived organoid biobank to model tumor heterogeneity and therapeutic vulnerability for oral squamous cell carcinoma

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1. scibot 19 Feb 2026
  
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  DOI: 10.1016/j.xcrm.2026.102622
  
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sciencedirect.com/science/article/pii/S266637912600039X
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Extracellular matrix sensing regulates intratumoral heterogeneity of autophagic flux

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1. scibot 19 Feb 2026
  
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  DOI: 10.1016/j.cell.2025.12.053
  
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sciencedirect.com/science/article/pii/S0092867425015028
Jan 2026
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Enterococcus faecalis-derived lactic acid suppresses macrophage activation to facilitate persistent and polymicrobial wound infections

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1. scibot 29 Jan 2026
  
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  DOI: 10.1016/j.chom.2026.01.002
  
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sciencedirect.com/science/article/pii/S1931312826000028
Nov 2025
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Regulatory T cell stability determines the efficiency of bile duct regeneration during cholangitis

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1. scibot 18 Nov 2025
  
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  DOI: 10.1016/j.celrep.2025.116557
  
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sciencedirect.com/science/article/pii/S2211124725013282
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YAP/TAZ transcriptional co-activators create therapeutic vulnerability to verteporfin in EGFR mutant glioblastoma

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1. scibot 08 Nov 2025
  
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  DOI: 10.1158/1078-0432.CCR-20-0018
  
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pmc.ncbi.nlm.nih.gov/articles/PMC8440125/
Oct 2025
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CANDiT: A machine learning framework for differentiation therapy in colorectal cancer

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1. scibot 22 Oct 2025
  
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  DOI: 10.1016/j.xcrm.2025.102421
  
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1-s2.0-S2589004225020425-main-html.html

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1. scibot 16 Oct 2025
  
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54.241.53.176/1ff1875e639b0b0d0f3166525c391e6a43509e7f/1-s2.0-S2589004225020425-main-html.html
Aug 2025
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HBV Remodels PP2A Complexes to Rewire Kinase Signaling in Hepatocellular Carcinoma

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1. scibot 19 Aug 2025
  
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  DOI: 10.1158/0008-5472.CAN-24-0456
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11949624/
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Autophagy suppresses the formation of hepatocyte-derived cancer-initiating ductular progenitor cells in the liver

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1. scibot 14 Aug 2025
  
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  DOI: 10.1126/sciadv.abf9141
  
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science.org/doi/10.1126/sciadv.abf9141
Jul 2025
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Therapeutic targeting of syndecan-1 axis overcomes acquired resistance to KRAS-targeted therapy in gastrointestinal cancers

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1. scibot 29 Jul 2025
  
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  DOI: 10.1016/j.xcrm.2025.102253
  
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Matrix Stiffness Regulates TGFβ1‐Induced αSMA Expression via a G9a‐LATS‐YAP Signaling Cascade

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1. scibot 16 Jul 2025
  
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  DOI: 10.1096/fba.2025-00117
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12256985/
Jun 2025
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Dynamic decoding of VEGF signaling and coordinated control of multiple phenotypes by the Src-TEM4-YAP pathway

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1. scibot 21 Jun 2025
  
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  DOI: 10.1016/j.cels.2025.101321
  
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sciencedirect.com/science/article/pii/S2405471225001541
Mar 2025
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Ginsenoside Rg1 alleviates chronic stress-induced depression in rats by targeting Cx43-YAP axis

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1. scibot 11 Mar 2025
  
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  DOI: 10.1038/s41401-025-01515-9
  
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link.springer.com/article/10.1038/s41401-025-01515-9
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The STRIPAK complex is required for radial sorting and laminin receptor expression in Schwann cells

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1. scibot 11 Mar 2025
  
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  DOI: 10.1016/j.celrep.2025.115401
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12035956/
Feb 2025
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N-cadherin-triggered myosin II inactivation provides tumor cells with a mechanical cell competition advantage and chemotherapy resistance

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1. scibot 25 Feb 2025
  
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  DOI: 10.1016/j.devcel.2025.01.020
  
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sciencedirect.com/science/article/pii/S1534580725000619
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Peptide PDHPS1 inhibits ovarian cancer growth through disrupting YAP signaling

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1. scibot 13 Feb 2025
  
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  DOI: 10.1158/1535-7163.MCT-21-0848
  
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aacrjournals.org/mct/article/21/7/1160/705294/Peptide-PDHPS1-Inhibits-Ovarian-Cancer-Growth
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Biguanides antithetically regulate tumor properties by the dose-dependent mitochondrial reprogramming-driven c-Src pathway

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1. scibot 11 Feb 2025
  
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  DOI: 10.1016/j.xcrm.2025.101941
  
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sciencedirect.com/science/article/pii/S266637912500014X
Dec 2024
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can-24-0456-html.html

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1. scibot 13 Dec 2024
  
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  DOI: 10.1158/0008-5472.can-24-0456
  
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52.53.155.43/e3985cf6f143830bda4dc2c0ff3a15e131833b3e/can-24-0456-html.html
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Integrative pathway analysis across humans and 3D cellular models identifies the p38 MAPK-MK2 axis as a therapeutic target for Alzheimer’s disease

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1. scibot 02 Dec 2024
  
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  DOI: 10.1016/j.neuron.2024.10.029
  
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sciencedirect.com/science/article/pii/S0896627324008006
Nov 2024
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Time-resolved proximity proteomics uncovers a membrane tension-sensitive caveolin-1 interactome at the rear of migrating cells

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1. scibot 07 Nov 2024
  
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  DOI: 10.7554/eLife.85601
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11509677/
Oct 2024
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Enhancer reprogramming underlies therapeutic utility of a SMARCA2 degrader in SMARCA4 mutant cancer

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1. scibot 09 Oct 2024
  
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  DOI: 10.1016/j.chembiol.2024.09.004
  
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sciencedirect.com/science/article/pii/S2451945624003969
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Salsolinol as an RNA m6A methylation inducer mediates dopaminergic neuronal death by regulating YAP1 and autophagy

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1. scibot 02 Oct 2024
  
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  DOI: 10.4103/NRR.NRR-D-23-01592
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11433901/
Sep 2024
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PDIA3 defines a novel subset of adipose macrophages to exacerbate the development of obesity and metabolic disorders

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1. scibot 25 Sep 2024
  
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  DOI: 10.1016/j.cmet.2024.08.009
  
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GRP94 Promotes Anoikis Resistance and Peritoneal Metastasis through YAP/TEAD1 pathway in Gastric Cancer

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1. scibot 12 Sep 2024
  
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  DOI: 10.1016/j.isci.2024.110638
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11381759/
Aug 2024
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METTL3 regulates cartilage development and homeostasis by affecting Lats1 mRNA stability in an m6A-YTHDF2-dependent manner

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  DOI: 10.1016/j.celrep.2024.114535
  
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cell.com/cell-reports/fulltext/S2211-1247(24)00864-7
Jul 2024
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ADAMTS18-fibronectin interaction regulates the morphology of liver sinusoidal endothelial cells

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  DOI: 10.1016/j.isci.2024.110273
  
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BPS Publications

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1. scibot 18 Jul 2024
  
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  DOI: 10.1111/bph.16494
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16494
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ATP-dependent citrate lyase Drives Left Ventricular Dysfunction by Metabolic Remodeling of the Heart

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  DOI: 10.1101/2024.06.21.600099
  
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biorxiv.org/content/10.1101/2024.06.21.600099v1
Jun 2024
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Hippo-PKCζ-NFκB signaling axis: A druggable modulator of chondrocyte responses to mechanical stress

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  DOI: 10.1016/j.isci.2024.109983
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11140209/
Apr 2024
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Generation of human alveolar epithelial type I cells from pluripotent stem cells

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  DOI: 10.1016/j.stem.2024.03.017
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11147407/
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NIBR-LTSi is a selective LATS kinase inhibitor activating YAP signaling and expanding tissue stem cells in vitro and in vivo

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1. scibot 05 Apr 2024
  
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  DOI: 10.1016/j.stem.2024.03.003
  
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sciencedirect.com/science/article/pii/S1934590924000845
Feb 2024
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Integrative modelling and analysis of signalling crosstalk reveal molecular switches coordinating YAP transcriptional activities

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1. scibot 23 Feb 2024
  
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  DOI: 10.1016/j.isci.2024.109031
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10877689/
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YAP-mediated GPER signaling impedes proliferation and survival of prostate epithelium in benign prostatic hyperplasia

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1. scibot 09 Feb 2024
  
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  DOI: 10.1016/j.isci.2024.109125
  
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52.53.155.43/3b983d9532a50e2ebeba730d1190ef88722ceb9a/PIIS2589004224003468-html.html
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YTHDF2-mediated circYAP1 drives immune escape and cancer progression through activating YAP1/TCF4-PD-L1 axis

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  DOI: 10.1016/j.isci.2023.108779
  
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Homology and the evolution of vocal folds in the novel avian voice box

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Epinephrine inhibits PI3Kα via the Hippo kinases

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Mitoguardin 1 and 2 promote granulosa cell proliferation by activating AKT and regulating the Hippo-YAP1 signaling pathway

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High-throughput chemogenetic drug screening reveals PKC-RhoA/PKN as a targetable signaling vulnerability in GNAQ-driven uveal melanoma

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MAP4Ks inhibition promotes retinal neuron regeneration from Müller glia in adult mice

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IGF1R inhibition enhances the therapeutic effects of Gq/11 inhibition in metastatic uveal melanoma progression

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Jun 2023
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TRIM21 is a druggable target for the treatment of metastatic colorectal cancer through ubiquitination and activation of MST2

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Reprogramming of Iron Metabolism Confers Ferroptosis Resistance in ECM-Detached Cells

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LAPTM4B-YAP loop feedback amplification enhances the stemness of hepatocellular carcinoma

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Extracellular vesicles in fatty liver promote a metastatic tumor microenvironment

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Lysine long-chain fatty acylation regulates the TEAD transcription factor

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YAP regulates the liver size during the fasting-refeeding transition in mice

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Cross-talk between TSC2 and the extracellular matrix controls pulmonary vascular proliferation and pulmonary hypertension

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Effect of inactivation of Mst1 and Mst2 in the mouse adrenal cortex

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A nuclear cAMP microdomain suppresses tumor growth by Hippo pathway inactivation

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Poziotinib for EGFR exon 20-mutant NSCLC: Clinical efficacy, resistance mechanisms, and impact of insertion location on drug sensitivity

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Jun 2022
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mct-21-0848-html.html

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The granulosa cell response to luteinizing hormone is partly mediated by YAP1-dependent induction of amphiregulin

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Counteractive and cooperative actions of muscle β-catenin and CaV1.1 during early neuromuscular synapse formation

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Mst1/2 is necessary for satellite cell differentiation to promote muscle regeneration

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Substrate rigidity dictates colorectal tumorigenic cell stemness and metastasis via CRAD-dependent mechanotransduction

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Renal Subcapsular Delivery of PGE2 Promotes Kidney Repair by Activating Endogenous Sox9+ Stem Cells

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Increased ACTL6A occupancy within mSWI/SNF chromatin remodelers drives human squamous cell carcinoma

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Senescent immune cells release grancalcin to promote skeletal aging

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Stabilization of Motin family proteins in NF2-deficient cells prevents full activation of YAP/TAZ and rapid tumorigenesis

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Exocyst protein subnetworks integrate Hippo and mTOR signaling to promote virus detection and cancer

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Untitled document

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Autophagy suppresses the formation of hepatocyte-derived cancer-initiating ductular progenitor cells in the liver

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Cell size homeostasis is maintained by CDK4-dependent activation of p38 MAPK

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Oxygen regulates epithelial stem cell proliferation via RhoA-actomyosin-YAP/TAZ signal in mouse incisor

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The ZMYND8-regulated mevalonate pathway endows YAP-high intestinal cancer with metabolic vulnerability

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Scribble sub-cellular localization modulates recruitment of YES1 to regulate YAP1 phosphorylation

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S1PR3–G12-biased agonist ALESIA targets cancer metabolism and promotes glucose starvation

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Constitutive androstane receptor induced-hepatomegaly is partially via yes-associated protein activation

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Actionable Cytopathogenic Host Responses of Human Alveolar Type 2 Cells to SARS-CoV-2

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Treatment-Induced Tumor Dormancy through YAP-Mediated Transcriptional Reprogramming of the Apoptotic Pathway

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  RRID:AB_2650553
  
  DOI: 10.1016/j.ccell.2019.12.006
  
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sciencedirect.com/science/article/pii/S1535610819305768
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Targeted disruption of Lats1 and Lats2 in mice impairs adrenal cortex development and alters adrenocortical cell fate

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  DOI: 10.1210/endocr/bqaa052
  
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academic.oup.com/endo/article/161/6/bqaa052/5815549
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Periostin Promotes Colorectal Tumorigenesis through Integrin-FAK-Src Pathway-Mediated YAP/TAZ Activation

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1. scibot 04 Sep 2020
  
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  DOI: 10.1016/j.celrep.2019.12.075
  
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sciencedirect.com/science/article/pii/S2211124719317401
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Kindlin-2 Inhibits the Hippo Signaling Pathway by Promoting Degradation of MOB1

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.celrep.2019.11.035
  
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Sphingosine 1‐phosphate but not Fingolimod protects neurons against excitotoxic cell death by inducing neurotrophic gene expression in astrocytes

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1. scibot 13 Jan 2020
  
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  DOI: 10.1111/jnc.14917
  
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onlinelibrary.wiley.com/doi/10.1111/jnc.14917
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BPS Publications

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1. scibot 13 Jan 2020
  
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  DOI: 10.1111/bph.14674
  
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YAP/TAZ Activation Drives Uveal Melanoma Initiation and Progression

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.celrep.2019.03.021
  
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Untitled document

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.celrep.2019.03.091
  
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sciencedirect.com/science/article/pii/S2211124719304309
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Untitled document

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1. scibot 12 Jan 2020
  
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  RRID:AB_2650553
  
  DOI: 10.1016/j.celrep.2019.01.076
  
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OTUB2 Promotes Cancer Metastasis via Hippo-Independent Activation of YAP and TAZ

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1. scibot 12 Jan 2020
  
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  DOI: 10.1016/j.molcel.2018.10.030
  
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sciencedirect.com/science/article/pii/S1097276518308906
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Losmapimod Overcomes Gefitinib Resistance in Non-small Cell Lung Cancer by Preventing Tetraploidization

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1. scibot 05 Nov 2018
  
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Nov 2017
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An FAK-YAP-mTOR Signaling Axis Regulates Stem Cell-Based Tissue Renewal in Mice

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1. scibot 08 Nov 2017
  
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sciencedirect.com/science/article/pii/S1934590917300942

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