161 Matching Annotations
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    IL-25-induced memory type 2 innate lymphoid cells enforce mucosal immunity
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  3. Aug 2025
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    Selective Alanine Transporter Utilization is a Therapeutic Vulnerability in ARID1A-Mutant Ovarian Cancer
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    Aging-induced semaphorin 7a promotes TGF-β1-mediated cell plasticity and breast tumor metastases
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    Exercise-induced microbiota metabolite enhances CD8 T cell antitumor immunity promoting immunotherapy efficacy
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    Activated T Cells Break Tumor Immunosuppression by Macrophage Reeducation
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    Mutant p53 exploits enhancers to elevate immunosuppressive chemokine expression and impair immune checkpoint inhibitors in pancreatic cancer
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    A first-in-class EGFR-directed KRAS G12V selective inhibitor
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    A percolation phase transition controls complement protein coating of surfaces
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  14. May 2025
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    Enhancer-driven gene regulatory networks reveal transcription factors governing T cell adaptation and differentiation in the tumor microenvironment
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    Interleukin-34-dependent perivascular macrophages promote vascular function in the brain
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    Nerve- and airway-associated interstitial macrophages mitigate SARS-CoV-2 pathogenesis via type I interferon signaling
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    Semaphorin7A and PD-L1 cooperatively drive immunosuppression during mammary involution and breast cancer
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    Regulatory T cells suppress GM-CSF-producing T helper cells via IL-2 modulation to restrain immunopathology
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    Understanding and reversing mammary tumor-driven reprogramming of myelopoiesis to reduce metastatic spread
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  21. Apr 2025
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    An iron-rich subset of macrophages promotes tumor growth through a Bach1-Ednrb axis
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    The metabolic sensor LKB1 regulates ILC3 homeostasis and mitochondrial function
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  25. Mar 2025
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    A transcriptional atlas of gut-innervating neurons reveals activation of interferon signaling and ferroptosis during intestinal inflammation
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    A heart-brain-spleen axis controls cardiac remodeling to hypertensive stress
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    Methionine regulates maternal-fetal immune tolerance and endometrial receptivity by enhancing embryonic IL-5 secretion
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  31. Jan 2025
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    Myocarditis and neutrophil-mediated vascular leakage but not cytokine storm associated with fatal murine leptospirosis
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    KDM6B-dependent epigenetic programming of uterine fibroblasts in early pregnancy regulates parturition timing in mice
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    Targeting the mevalonate pathway potentiates NUAK1 inhibition-induced immunogenic cell death and antitumor immunity
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  35. Dec 2024
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    Extracellular nicotinamide phosphoribosyltransferase (eNAMPT) drives abnormal pericyte-rich vasculature in triple-negative breast cancer
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    The ribotoxic stress response drives acute inflammation, cell death, and epidermal thickening in UV-irradiated skin in vivo
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  38. Nov 2024
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    Differential contributions of fetal mononuclear phagocytes to Zika virus neuroinvasion versus neuroprotection during congenital infection
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  40. Sep 2024
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    Mutant p53 Exploits Enhancers to Elevate Immunosuppressive Chemokine Expression and Impair Immune Checkpoint Inhibitors in Pancreatic Cancer
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    Hyperactivating EZH2 to augment H3K27me3 levels in regulatory T cells enhances immune suppression by driving early effector differentiation
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    PlexinB1 Inactivation Reprograms Immune Cells in the Tumor Microenvironment, Inhibiting Breast Cancer Growth and Metastatic Dissemination
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    Application of a bespoke monoclonal antibody panel to characterize immune cell populations in cave nectar bats
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    Non-classical monocytes scavenge the growth factor CSF1 from endothelial cells in the peripheral vascular tree to ensure survival and homeostasis
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  52. Jul 2024
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    Single-cell chromatin accessibility and transposable element landscapes reveal shared features of tissue-residing immune cells
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    A synbiotic of Anaerostipes caccae and lactulose prevents and treats food allergy in mice
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    Progestogen-driven B7-H4 contributes to onco-fetal immune tolerance
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    Sugar and arginine facilitate oral tolerance by ensuring the functionality of tolerogenic immune cell subsets in the intestine
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    A specialized population of monocyte-derived tracheal macrophages promote airway epithelial regeneration through a CCR2-dependent mechanism
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    Redefining the ontogeny of hyalocytes as yolk sac-derived tissue-resident macrophages of the vitreous body
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  60. May 2024
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    Circadian tumor infiltration and function of CD8+ T cells dictate immunotherapy efficacy
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    A CTCF-binding site in the Mdm1-Il22-Ifng locus shapes cytokine expression profiles and plays a critical role in early Th1 cell fate specification
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  63. Apr 2024
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    The diversity of inhibitory receptor co-expression patterns of exhausted CD8+ T cells in oropharyngeal carcinoma
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    A LTB4/CD11b self-amplifying loop drives pyogranuloma formation in chronic granulomatous disease
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    Early-wave macrophages control late hematopoiesis
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  67. Mar 2024
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    ATF4-SLC7A11-GSH axis mediates the acquisition of immunosuppressive properties by activated CD4+ T cells in low arginine condition
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    Long-lasting mRNA-encoded interleukin-2 restores CD8+ T cell neoantigen immunity in MHC class I-deficient cancers
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    Wnt5 controls splenic myelopoiesis and neutrophil functional ambivalency during DSS-induced colitis
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  72. Feb 2024
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    Disruption of MerTK increases the efficacy of checkpoint inhibitor by enhancing ferroptosis and immune response in hepatocellular carcinoma
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    Interrogation of endothelial and mural cells in brain metastasis reveals key immune-regulatory mechanisms
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  76. Dec 2023
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    Aged intestinal stem cells propagate cell-intrinsic sources of inflammaging in mice
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    NK cells propagate T cell immunity following in situ tumor vaccination
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  80. Sep 2023
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    STING signaling promotes NK cell antitumor immunity and maintains a reservoir of TCF-1+ NK cells
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    mTORC2 orchestrates monocytic and granulocytic lineage commitment by an ATF5-mediated pathway
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    Homeostatic PD-1 signaling restrains EOMES-dependent oligoclonal expansion of liver-resident CD8 T cells
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    Synergism Between IL21 and Anti-PD-1 Combination Therapy is Underpinned by the Coordinated Reprogramming of the Immune Cellular Network in the Tumor Microenvironment
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  86. Jul 2023
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    Intestinal microbiota controls graft-versus-host disease independent of donor-host genetic disparity
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    A surgically optimized intraoperative poly(I:C)-releasing hydrogel prevents cancer recurrence
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    Macrophage-mediated extracellular matrix remodeling controls host Staphylococcus aureus susceptibility in the skin
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  90. Jun 2023
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    Neuroprotective protein ADNP-dependent histone remodeling complex promotes T helper 2 immune cell differentiation
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    Prolonged dysbiosis and altered immunity under nutritional intervention in a physiological mouse model of severe acute malnutrition
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  93. May 2023
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    M cell maturation and cDC activation determine the onset of adaptive immune priming in the neonatal Peyer’s patch
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  95. Apr 2023
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    Dietary tryptophan metabolite released by intratumoral Lactobacillus reuteri facilitates immune checkpoint inhibitor treatment
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    An immune cell lipid atlas reveals the basis of susceptibility to ferroptosis
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    Niche-expressed Galectin-1 is involved in pre-B acute lymphoblastic leukemia relapse through pre-BCR activation
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  99. Mar 2023
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    Formation and function of the meningeal arachnoid barrier around the developing mouse brain
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    ILC3s restrict the dissemination of intestinal bacteria to safeguard liver regeneration after surgery
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    Dietary tryptophan deficiency promotes gut RORγt+ Treg cells at the expense of Gata3+ Treg cells and alters commensal microbiota metabolism
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  103. Feb 2023
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    Circumvention of luteolysis reveals parturition pathways in mice dependent upon innate type 2 immunity
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  105. Jan 2023
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    CD4+ T cells drive an inflammatory, TNF-α/IFN-rich tumor microenvironment responsive to chemotherapy
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    Neutrophil-activating therapy for the treatment of cancer
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    Bispecific PD1-IL2v and anti-PD-L1 break tumor immunity resistance by enhancing stem-like tumor-reactive CD8+ T cells and reprogramming macrophages
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    Microbiota-dependent proteolysis of gluten subverts diet-mediated protection against type 1 diabetes
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  110. Dec 2022
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    Recruited monocytes/macrophages drive pulmonary neutrophilic inflammation and irreversible lung tissue remodeling in cystic fibrosis
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    IL-5-producing CD4+ T cells and eosinophils cooperate to enhance response to immune checkpoint blockade in breast cancer
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  113. Nov 2022
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    FABP5 controls macrophage alternative activation and allergic asthma by selectively programming long-chain unsaturated fatty acid metabolism
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  115. Oct 2022
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    A Microarray Patch SARS-CoV-2 Vaccine Induces Sustained Antibody Responses and Polyfunctional Cellular Immunity
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  117. Sep 2022
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    Mucosal plasma cells are required to protect the upper airway and brain from infection
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