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An interactome-based framework for DDB1- and CUL4-associated factor prioritization in targeted protein degradation

1
1. scibot 09 Apr 2026
  
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  RRID:AB_2665504
  
  DOI: 10.1016/j.molcel.2026.03.004
  
  Resource: (Cell Signaling Technology Cat# 14475, RRID:AB_2665504)
  
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sciencedirect.com/science/article/pii/S1097276526001607
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Selective degradation of TBK1 uncovers mechanistic insights into blocking ccRCC progression

1
1. scibot 09 Apr 2026
  
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  RRID:AB_2665504
  
  DOI: 10.1016/j.chembiol.2026.03.013
  
  Resource: (Cell Signaling Technology Cat# 14475, RRID:AB_2665504)
  
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sciencedirect.com/science/article/pii/S2451945626001054
Jan 2026
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Splice-switching ASOs targeting the AURKA 5′ UTR collapse an SRSF1-AURKA-MYC oncogenic circuit in pancreatic cancer

1
1. scibot 06 Jan 2026
  
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  RRID:AB_2665504
  
  DOI: 10.1016/j.molcel.2025.12.004
  
  Resource: (Cell Signaling Technology Cat# 14475, RRID:AB_2665504)
  
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sciencedirect.com/science/article/pii/S1097276525009785
Jul 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Retinoic acid-induced 2 deficiency impairs genomic stability in breast cancer

1
1. scibot 25 Jul 2025
  
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  AB_2665504
  
  DOI: 10.1186/s13058-025-02085-8
  
  Resource: (Cell Signaling Technology Cat# 14475, RRID:AB_2665504)
  
  Curator: @sonofthor
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12285165/
May 2025
52.53.155.43 52.53.155.43

1-s2.0-S2589004225008454-main-html.html

1
1. scibot 18 May 2025
  
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  RRID:AB_2665504
  
  DOI: 10.1016/j.isci.2025.112584
  
  Resource: (Cell Signaling Technology Cat# 14475, RRID:AB_2665504)
  
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52.53.155.43/2f59eea255f6dfa2798e1e0fcb3d7e10d3ba6bc8/1-s2.0-S2589004225008454-main-html.html
Aug 2024
www.cell.com www.cell.com

Activated dormant stem cells recover spermatogenesis in chemoradiotherapy-induced infertility

1
1. scibot 18 Aug 2024
  
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  RRID:AB_2665504
  
  DOI: 10.1016/j.celrep.2024.114582
  
  Resource: (Cell Signaling Technology Cat# 14475, RRID:AB_2665504)
  
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cell.com/cell-reports/fulltext/S2211-1247(24)00911-2
Nov 2023
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Unbiased interrogation of functional lysine residues in human proteome

1
1. scibot 28 Nov 2023
  
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  RRID:AB_2665504
  
  DOI: 10.1016/j.molcel.2023.10.033
  
  Resource: (Cell Signaling Technology Cat# 14475, RRID:AB_2665504)
  
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sciencedirect.com/science/article/pii/S1097276523008705
Mar 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

CHD1 promotes sensitivity to Aurora kinase inhibitors by suppressing interaction of AURKA with its coactivator TPX2

1
1. scibot 05 Mar 2023
  
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  RRID:AB_2665504
  
  DOI: 10.1158/0008-5472.CAN-22-0631
  
  Resource: (Cell Signaling Technology Cat# 14475, RRID:AB_2665504)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9444962/
Oct 2022
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Acute pharmacological degradation of ERK5 does not inhibit cellular immune response or proliferation

1
1. scibot 11 Oct 2022
  
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  RRID:AB_2665504
  
  DOI: 10.1016/j.chembiol.2022.09.004
  
  Resource: (Cell Signaling Technology Cat# 14475, RRID:AB_2665504)
  
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sciencedirect.com/science/article/pii/S245194562200352X
Aug 2022
52.53.155.43 52.53.155.43

can-22-0631-html.html

2
1. scibot 27 Aug 2022
  
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  RRID: AB_2665504
  
  DOI: 10.1158/0008-5472.CAN-22-0631
  
  Resource: (Cell Signaling Technology Cat# 14475, RRID:AB_2665504)
  
  Curator: @a5munoz
  
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2. scibot 27 Aug 2022
  
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  RRID:AB_2665504
  
  DOI: 10.1158/0008-5472.can-22-0631
  
  Resource: (Cell Signaling Technology Cat# 14475, RRID:AB_2665504)
  
  Curator: @scibot
  
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52.53.155.43/eb3d97bd3689fdec423c36bb1ce8ba7443cda401/can-22-0631-html.html
May 2022
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AURKA and PLK1 inhibition selectively and synergistically block cell cycle progression in diffuse midline glioma

1
1. scibot 26 May 2022
  
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  RRID:AB_2665504
  
  DOI: 10.1016/j.isci.2022.104398
  
  Resource: (Cell Signaling Technology Cat# 14475, RRID:AB_2665504)
  
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sciencedirect.com/science/article/pii/S2589004222006691
www.cell.com www.cell.com

Systematic discovery of mutation-directed neo-protein-protein interactions in cancer

1
1. scibot 05 May 2022
  
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  RRID:AB_2665504
  
  DOI: 10.1016/j.cell.2022.04.014
  
  Resource: (Cell Signaling Technology Cat# 14475, RRID:AB_2665504)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2665504
  
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cell.com/cell/fulltext/S0092-8674(22)00461-5
Aug 2021
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Targeting Aurora B kinase prevents and overcomes resistance to EGFR inhibitors in lung cancer by enhancing BIM- and PUMA-mediated apoptosis

1
1. scibot 16 Aug 2021
  
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  RRID:AB_2665504
  
  DOI: 10.1016/j.ccell.2021.07.006
  
  Resource: (Cell Signaling Technology Cat# 14475, RRID:AB_2665504)
  
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sciencedirect.com/science/article/pii/S1535610821003834
May 2021
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Proline Hydroxylation Primes Protein Kinases for Autophosphorylation and Activation

1
1. scibot 07 May 2021
  
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  RRID:AB_2665504
  
  DOI: 10.1016/j.molcel.2020.06.021
  
  Resource: (Cell Signaling Technology Cat# 14475, RRID:AB_2665504)
  
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sciencedirect.com/science/article/pii/S1097276520304238
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Sarcomere function activates a p53-dependent DNA damage response that promotes polyploidization and limits in vivo cell engraftment

1
1. scibot 05 May 2021
  
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  RRID:AB_2665504
  
  DOI: 10.1016/j.celrep.2021.109088
  
  Resource: (Cell Signaling Technology Cat# 14475, RRID:AB_2665504)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S2211124721004216
Mar 2021
www.sciencedirect.com www.sciencedirect.com

Alisertib inhibits migration and invasion of EGFR-TKI resistant cells by partially reversing the epithelial-mesenchymal transition

1
1. scibot 30 Mar 2021
  
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  AURKA
  
  DOI: 10.1016/j.bbamcr.2021.119016
  
  Resource: (Cell Signaling Technology Cat# 14475, RRID:AB_2665504)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2665504
  
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  RRIDCUR:Missing RRID:AB_2665504
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sciencedirect.com/science/article/pii/S0167488921000707
Dec 2020
www.sciencedirect.com www.sciencedirect.com

Mapping the Degradable Kinome Provides a Resource for Expedited Degrader Development

1
1. scibot 11 Dec 2020
  
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  RRID:AB_2665504
  
  DOI: 10.1016/j.cell.2020.10.038
  
  Resource: (Cell Signaling Technology Cat# 14475, RRID:AB_2665504)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2665504
  
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  RRIDCUR:Validated RRID:AB_2665504
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RRID:AB_2665504

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sciencedirect.com/science/article/pii/S0092867420314458
Nov 2018
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A Chemoproteomic Approach to Query the Degradable Kinome Using a Multi-kinase Degrader

1
1. scibot 05 Nov 2018
  
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  RRID:AB_2665504
  
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  (Cell Signaling Technology Cat# 14475, RRID:AB_2665504)
  
  SciCrunch record: RRID:AB_2665504
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
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  RRID:AB_2665504
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ncbi.nlm.nih.gov/pmc/articles/PMC6427047/