34 Matching Annotations
  1. Last 7 days
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    Leucyl-tRNA synthetase contributes to muscle weakness through mTORC1 activation and autophagy suppression in a mouse model of Duchenne Muscular Dystrophy
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    1. scibot 17 May 2024
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      DOI: 10.1016/j.ajpath.2024.04.006

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    sciencedirect.com/science/article/pii/S0002944024001743
  3. Feb 2024
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    Trichinella spiralis inhibits myoblast differentiation by targeting SQSTM1/p62 with a secreted E3 ubiquitin ligase
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    1. scibot 16 Feb 2024
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      DOI: 10.1016/j.isci.2024.109102

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    2. scibot 16 Feb 2024
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      DOI: 10.1016/j.isci.2024.109102

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    sciencedirect.com/science/article/pii/S2589004224003237
  5. 52.53.155.43 52.53.155.43
    mTOR regulates mineralocorticoid receptor transcriptional activity by ULK1- dependent and independent mechanisms
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    1. scibot 15 Feb 2024
      AB_2665508

      DOI: 10.1210/endocr/bqae015

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    52.53.155.43/6951e0010ae4c14df11b3315f954e81c6a9c88a4/bqae015-html.html
  6. Jan 2024
  7. www.sciencedirect.com www.sciencedirect.com
    Disruption of lysosomal nutrient sensing scaffold hyperactivates mTORC1 contributing to pathogenesis of a fatal neurodegenerative disease
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    1. scibot 11 Jan 2024
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      DOI: 10.1016/j.jbc.2024.105641

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    sciencedirect.com/science/article/pii/S0021925824000176
  8. Nov 2023
  9. www.sciencedirect.com www.sciencedirect.com
    The tRNA-GCN2-FBXO22-axis-mediated mTOR ubiquitination senses amino acid insufficiency
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    1. scibot 28 Nov 2023
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      DOI: 10.1016/j.cmet.2023.10.016

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    sciencedirect.com/science/article/abs/pii/S1550413123003856
  10. Oct 2023
  11. 52.53.155.43 52.53.155.43
    s41586-023-06657-6_reference-html.html
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    1. scibot 06 Oct 2023
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      DOI: 10.1038/s41586-023-06657-6

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    52.53.155.43/0f3eb7b8d15ef36be47b7c18ecdf1d19ad34ca1a/s41586-023-06657-6_reference-html.html
  12. May 2023
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    Exhaustion-associated cholesterol deficiency dampens the cytotoxic arm of antitumor immunity
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    1. scibot 27 May 2023
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      DOI: 10.1016/j.ccell.2023.04.016

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    sciencedirect.com/science/article/pii/S1535610823001423
  14. Apr 2023
  15. europepmc.org europepmc.org
    A Novel Method for Visualizing In-Vivo Rates of Protein Degradation Provides Insight into how TRIM28 Regulates Muscle Size
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    1. scibot 20 Apr 2023
      RRID:AB_2665508

      DOI: 10.1016/j.isci.2023.106526

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    europepmc.org/article/pmc/pmc10105291
  16. Dec 2022
  17. www.sciencedirect.com www.sciencedirect.com
    Lysine crotonylation regulates leucine-deprivation-induced autophagy by a 14-3-3ε-PPM1B axis
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    1. scibot 24 Dec 2022
      RRID:AB_2665508

      DOI: 10.1016/j.celrep.2022.111850

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    sciencedirect.com/science/article/pii/S2211124722017429
  18. www.sciencedirect.com www.sciencedirect.com
    Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis
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    1. scibot 24 Dec 2022
      RRID:AB_2665508

      DOI: 10.1016/j.celrep.2022.111834

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    sciencedirect.com/science/article/pii/S2211124722017260
  19. Aug 2022
  20. www.sciencedirect.com www.sciencedirect.com
    Hyperactivation of mTOR and AKT in a cardiac hypertrophy animal model of Friedreich ataxia
    1
    1. scibot 27 Aug 2022
      RRID:AB_266550

      DOI: 10.1016/j.heliyon.2022.e10371

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    sciencedirect.com/science/article/pii/S2405844022016590
  21. Apr 2022
  22. www.sciencedirect.com www.sciencedirect.com
    Cholesterol suppresses GOLM1-dependent selective autophagy of RTKs in hepatocellular carcinoma
    1
    1. scibot 21 Apr 2022
      RRID:AB_2665508

      DOI: 10.1016/j.celrep.2022.110712

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    sciencedirect.com/science/article/pii/S2211124722004739
  23. Jan 2022
  24. www.sciencedirect.com www.sciencedirect.com
    Pegylated arginine deiminase drives arginine turnover and systemic autophagy to dictate energy metabolism
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    1. scibot 19 Jan 2022
      RRID:AB_2665508

      DOI: 10.1016/j.xcrm.2021.100498

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    sciencedirect.com/science/article/pii/S266637912100375X
  25. Aug 2021
  26. www.sciencedirect.com www.sciencedirect.com
    Protocol to study starvation-induced autophagy in developing rat neurons
    1
    1. scibot 15 Aug 2021
      RRID:AB_2665508

      DOI: 10.1016/j.xpro.2021.100713

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    sciencedirect.com/science/article/pii/S2666166721004202
  27. Jul 2021
  28. www.sciencedirect.com www.sciencedirect.com
    SREBP-1c impairs ULK1 sulfhydration-mediated autophagic flux to promote hepatic steatosis in high-fat-diet-fed mice
    1
    1. scibot 07 Jul 2021
      RRID:AB_2665508

      DOI: 10.1016/j.molcel.2021.06.003

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    sciencedirect.com/science/article/pii/S1097276521004500
  29. Jun 2021
  30. www.sciencedirect.com www.sciencedirect.com
    Glucose starvation induces autophagy via ULK1-mediated activation of PIKfyve in an AMPK-dependent manner
    1
    1. scibot 09 Jun 2021
      RRID:AB_2665508

      DOI: 10.1016/j.devcel.2021.05.010

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    sciencedirect.com/science/article/pii/S1534580721004391
  31. May 2021
  32. onlinelibrary.wiley.com onlinelibrary.wiley.com
    MicroRNA-3473b regulates the expression of TREM2/ULK1 and inhibits autophagy in inflammatory pathogenesis of Parkinson disease
    1
    1. scibot 20 May 2021
      RRID:AB_2665508

      DOI: 10.1111/jnc.15299

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    onlinelibrary.wiley.com/doi/10.1111/jnc.15299
  33. www.sciencedirect.com www.sciencedirect.com
    Acetyl-CoA Derived from Hepatic Peroxisomal β-Oxidation Inhibits Autophagy and Promotes Steatosis via mTORC1 Activation
    1
    1. scibot 07 May 2021
      RRID:AB_2665508

      DOI: 10.1016/j.molcel.2020.05.007

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    sciencedirect.com/science/article/pii/S1097276520303087
  34. www.sciencedirect.com www.sciencedirect.com
    Asparagine couples mitochondrial respiration to ATF4 activity and tumor growth
    1
    1. scibot 01 May 2021
      RRID:AB_2665508

      DOI: 10.1016/j.cmet.2021.02.001

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    sciencedirect.com/science/article/pii/S1550413121000577
  35. Apr 2021
  36. www.sciencedirect.com www.sciencedirect.com
    Caloric Restriction Promotes Immunometabolic Reprogramming Leading to Protection from Tuberculosis
    1
    1. scibot 30 Apr 2021
      RRID:AB_2665508

      DOI: 10.1016/j.cmet.2020.12.016

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    sciencedirect.com/science/article/pii/S1550413120306719
  37. Dec 2020
  38. www.sciencedirect.com www.sciencedirect.com
    Role of VAMP7-Dependent Secretion of Reticulon 3 in Neurite Growth
    1
    1. scibot 23 Dec 2020
      RRID:AB_2665508

      DOI: 10.1016/j.celrep.2020.108536

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    sciencedirect.com/science/article/pii/S2211124720315254
  39. elifesciences.org elifesciences.org
    Autophagy compensates for Lkb1 loss to maintain adult mice homeostasis and survival
    1
    1. scibot 09 Dec 2020
      RRID:AB_2665508

      DOI: 10.7554/eLife.62377

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    elifesciences.org/articles/62377
  40. Sep 2020
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    AMPK-dependent activation of the Cyclin Y/CDK16 complex controls autophagy
    1
    1. scibot 26 Sep 2020
      RRID:AB_2665508

      DOI: 10.1038/s41467-020-14812-0

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    ncbi.nlm.nih.gov/pmc/articles/PMC7042329/
  42. www.sciencedirect.com www.sciencedirect.com
    Cdk4 and Cdk6 Couple the Cell-Cycle Machinery to Cell Growth via mTORC1
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    1. scibot 23 Sep 2020
      RRID:AB_2665508

      DOI: 10.1016/j.celrep.2020.03.068

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    sciencedirect.com/science/article/pii/S2211124720303946
  43. www.sciencedirect.com www.sciencedirect.com
    Metabolic Control over mTOR-Dependent Diapause-like State
    1
    1. scibot 05 Sep 2020
      RRID:AB_2665508

      DOI: 10.1016/j.devcel.2019.12.018

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    sciencedirect.com/science/article/pii/S1534580719310676
  44. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Astroglial biotin deprivation under endoplasmic reticulum stress uncouples BCAA‐mTORC1 role in lipid synthesis to prolong autophagy inhibition in the aging brain
    1
    1. scibot 03 Sep 2020
      RRID:AB_2665508

      DOI: 10.1111/jnc.14979

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      Curator: @Naa003

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      Curator comments: Phospho-ULK1 (Ser757) (D7O6U) Rabbit mAb #14202 antibody Cell Signaling Technology Cat# 14202

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    onlinelibrary.wiley.com/doi/10.1111/jnc.14979
  45. Jan 2020
  46. www.sciencedirect.com www.sciencedirect.com
    RAD51AP1 Is an Essential Mediator of Alternative Lengthening of Telomeres
    1
    1. scibot 13 Jan 2020
      RRID:AB_2665508

      DOI: 10.1016/j.molcel.2019.06.043

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    sciencedirect.com/science/article/pii/S1097276519305003
  47. www.sciencedirect.com www.sciencedirect.com
    An mTORC1-to-CDK1 Switch Maintains Autophagy Suppression during Mitosis
    1
    1. scibot 13 Jan 2020
      RRID:AB_2665508

      DOI: 10.1016/j.molcel.2019.10.016

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      RRID:AB_2665508 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1097276519307944
  48. www.mdpi.com www.mdpi.com
    Tanshinone IIA Restores Dynamic Balance of Autophagosome/Autolysosome in Doxorubicin-Induced Cardiotoxicity via Targeting Beclin1/LAMP1
    1
    1. scibot 13 Jan 2020
      RRID:AB_2665508

      DOI: 10.3390/cancers11070910

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    mdpi.com/2072-6694/11/7/910/htm
  49. www.sciencedirect.com www.sciencedirect.com
    Lysosome Positioning Influences mTORC2 and AKT Signaling
    1
    1. scibot 13 Jan 2020
      RRID:AB_2665508

      DOI: 10.1016/j.molcel.2019.05.009

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      Curator: @ethanbadger

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    sciencedirect.com/science/article/pii/S1097276519303624
  50. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 13 Jan 2020
      RRID:AB_2665508

      DOI: 10.1016/j.cell.2019.01.030

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    sciencedirect.com/science/article/pii/S0092867419300935
  51. Nov 2018
  52. www.sciencedirect.com www.sciencedirect.com
    Helicobacter pylori Infection Modulates Host Cell Metabolism through VacA-Dependent Inhibition of mTORC1
    1
    1. scibot 05 Nov 2018
      RRID:AB_2665508

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    sciencedirect.com/science/article/pii/S1931312818302038
  53. Nov 2017
  54. www.sciencedirect.com www.sciencedirect.com
    DGAT1-Dependent Lipid Droplet Biogenesis Protects Mitochondrial Function during Starvation-Induced Autophagy
    1
    1. scibot 08 Nov 2017
      Rabbit monoclonal anti-Phospho-ULK1 (Ser757)Cell Signaling TechnologyCat. # 14202, D7O6U

      Curator: @Jmenke

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      RRID:AB_2665508 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S1534580717304598