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Oct 2025
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Spliceosome inhibition induces Z-RNA and ZBP1-driven cell death in small cell lung cancer

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  DOI: 10.1016/j.celrep.2025.116384
  
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sciencedirect.com/science/article/pii/S2211124725011556
Aug 2025
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TCF25 serves as a nutrient sensor to orchestrate metabolic adaptation and cell death by enhancing lysosomal acidification under glucose starvation

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1. scibot 26 Aug 2025
  
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  DOI: 10.1016/j.celrep.2025.116186
  
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sciencedirect.com/science/article/pii/S221112472500957X
Jul 2025
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MLKL activates the cGAS-STING pathway by releasing mitochondrial DNA upon necroptosis induction

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1. scibot 03 Jul 2025
  
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  DOI: 10.1016/j.molcel.2025.06.005
  
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sciencedirect.com/science/article/pii/S1097276525005052
May 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

A bacterial network of T3SS effectors counteracts host pro-inflammatory responses and cell death to promote infection

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1. scibot 19 May 2025
  
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  DOI: 10.1038/s44318-025-00412-5
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12048508/
Apr 2025
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ZBP1 senses splicing aberration through Z-RNA to promote cell death

1
1. scibot 24 Apr 2025
  
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  DOI: 10.1016/j.molcel.2025.03.023
  
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sciencedirect.com/science/article/pii/S1097276525002990
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MLKL activity requires a splicing-regulated, druggable intramolecular interaction

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1. scibot 10 Apr 2025
  
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  DOI: 10.1016/j.molcel.2025.03.015
  
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sciencedirect.com/science/article/pii/S109727652500259X
Dec 2024
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1-s2.0-S2589004224028086-main-html.html

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1. scibot 19 Dec 2024
  
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52.53.155.43/9f2a0ef4271b61fdfbdda27575922c2ba8834710/1-s2.0-S2589004224028086-main-html.html
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Infant feces-derived Lactobacillus gasseri FWJL-4 mitigates experimental necrotizing enterocolitis via acetate production

1
1. scibot 13 Dec 2024
  
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  DOI: 10.1080/19490976.2024.2430541
  
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tandfonline.com/doi/abs/10.1080/19490976.2024.2430541
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Infant feces-derived Lactobacillus gasseri FWJL-4 mitigates experimental necrotizing enterocolitis via acetate production

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1. scibot 13 Dec 2024
  
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  DOI: 10.1080/19490976.2024.2430541
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11633162/
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Interleukin-1α release during necrotic-like cell death generates myeloid-driven immunosuppression that restricts anti-tumor immunity

1
1. scibot 02 Dec 2024
  
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  DOI: 10.1016/j.ccell.2024.10.014
  
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sciencedirect.com/science/article/pii/S1535610824004021
Nov 2024
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Residue Y362 is crucial for FLIPL to impart catalytic activity to pro-caspase-8 to suppress necroptosis

1
1. scibot 11 Nov 2024
  
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  DOI: 10.1016/j.celrep.2024.114966
  
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sciencedirect.com/science/article/pii/S2211124724013172
Sep 2024
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Cecal necroptosis triggers lethal cardiac dysfunction in TNF-induced severe SIRS

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1. scibot 27 Sep 2024
  
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  DOI: 10.1016/j.celrep.2024.114778
  
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sciencedirect.com/science/article/pii/S221112472401129X
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CD14 is a decision-maker between Fas-mediated death and inflammation

1
1. scibot 04 Sep 2024
  
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  DOI: 10.1016/j.celrep.2024.114685
  
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sciencedirect.com/science/article/pii/S2211124724010362
Aug 2024
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Non-canonical autophosphorylation of RIPK1 drives timely pyroptosis to control Yersinia infection

1
1. scibot 22 Aug 2024
  
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  DOI: 10.1016/j.celrep.2024.114641
  
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sciencedirect.com/science/article/pii/S2211124724009914
Jul 2024
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Hepatocyte-macrophage crosstalk via the PGRN-EGFR axis modulates ADAR1-mediated immunity in the liver

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1. scibot 19 Jul 2024
  
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cell.com/cell-reports/abstract/S2211-1247(24)00728-9
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Extracellular vesicles from alveolar macrophages harboring phagocytosed methicillin-resistant Staphylococcus aureus induce necroptosis

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1. scibot 12 Jul 2024
  
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  DOI: 10.1016/j.celrep.2024.114453
  
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cell.com/cell-reports/fulltext/S2211-1247(24)00782-4
May 2024
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A RIPK1-specific PROTAC degrader achieves potent antitumor activity by enhancing immunogenic cell death

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1. scibot 24 May 2024
  
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  DOI: 10.1016/j.immuni.2024.04.025
  
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sciencedirect.com/science/article/pii/S1074761324002309
Apr 2024
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Edaravone Dexborneol mitigates pathology in animal and cell culture models of Alzheimer’s disease by inhibiting neuroinflammation and neuronal necroptosis

1
1. scibot 30 Apr 2024
  
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  DOI: 10.1186/s13578-024-01230-8
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11056062/
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BPS Publications

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1. scibot 11 Apr 2024
  
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  DOI: 10.1111/bph.16364
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16364
Mar 2024
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NLRP6 induces RIP1 kinase-dependent necroptosis via TAK1-mediated p38MAPK/MK2 phosphorylation in S. Typhimurium infection

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1. scibot 08 Mar 2024
  
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  DOI: 10.1016/j.isci.2024.109339
  
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52.53.155.43/edc059b1f8d2daaa9b02a6bfc9253e0bab800af6/1-s2.0-S2589004224005601-main-html.html
Jan 2024
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Lymph node and tumor-associated PD-L1+ macrophages antagonize dendritic cell vaccines by suppressing CD8+ T cells

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  DOI: 10.1016/j.xcrm.2023.101377
  
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sciencedirect.com/science/article/pii/S2666379123006067
Nov 2023
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Triggering endogenous Z-RNA sensing for anti-tumor therapy through ZBP1-dependent necroptosis

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1. scibot 10 Nov 2023
  
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  DOI: 10.1016/j.celrep.2023.113377
  
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sciencedirect.com/science/article/pii/S221112472301389X
Oct 2023
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Identification of hyperoxidized PRDX3 as a ferroptosis marker reveals ferroptotic damage in chronic liver diseases

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1. scibot 27 Oct 2023
  
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  DOI: 10.1016/j.molcel.2023.09.025
  
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sciencedirect.com/science/article/pii/S1097276523007529
Sep 2023
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Chronic Carbon Disulfide Exposure Induces Parkinsonian Pathology via α-Synuclein Aggregation and Necrosome Complex Interaction

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  DOI: 10.1016/j.isci.2023.107787
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10507234/
Aug 2023
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Evidence for developmental vascular-associated necroptosis and its contribution to venous-lymphatic endothelial differentiation

1
1. scibot 16 Aug 2023
  
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  DOI: 10.3389/fcell.2023.1229788
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10416103/
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Platelet ITGA2B inhibits caspase-8 and Rip3/Mlkl-dependent platelet death though PTPN6 during sepsis

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1. scibot 10 Aug 2023
  
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  DOI: 10.1016/j.isci.2023.107414
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10404729/
Jul 2023
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Nucleoporin Seh1 maintains Schwann cell homeostasis by regulating genome stability and necroptosis

1
1. scibot 21 Jul 2023
  
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  DOI: 10.1016/j.celrep.2023.112802
  
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sciencedirect.com/science/article/pii/S2211124723008136
Jun 2023
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Sublethal necroptosis signaling promotes inflammation and liver cancer

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  DOI: 10.1016/j.immuni.2023.05.017
  
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sciencedirect.com/science/article/pii/S1074761323002340
May 2023
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C5a-licensed phagocytes drive sterilizing immunity during systemic fungal infection

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1. scibot 24 May 2023
  
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  DOI: 10.1016/j.cell.2023.04.031
  
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sciencedirect.com/science/article/pii/S0092867423004658
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Necrostatin-1 decreases necroptosis and inflammatory... : Neural Regeneration Research

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  DOI: 10.4103/1673-5374.339488
  
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journals.lww.com/nrronline/Fulltext/2022/12000/Necrostatin_1_decreases_necroptosis_and.37.aspx
Aug 2022
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Endocytic membrane repair by ESCRT-III controls antigen export to the cytosol during antigen cross-presentation

1
1. scibot 17 Aug 2022
  
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  DOI: 10.1016/j.celrep.2022.111205
  
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sciencedirect.com/science/article/pii/S2211124722010221
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Mitochondrial ROS promotes susceptibility to infection via gasdermin D-mediated necroptosis

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  DOI: 10.1016/j.cell.2022.06.038
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9531054/
Jul 2022
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Ubiquitylation of RIPK3 beyond-the-RHIM can limit RIPK3 activity and cell death

1
1. scibot 08 Jul 2022
  
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  DOI: 10.1016/j.isci.2022.104632
  
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sciencedirect.com/science/article/pii/S258900422200904X
May 2022
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Necrostatin-1 decreases necroptosis and inflammatory... : Neural Regeneration Research

1
1. scibot 05 May 2022
  
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  DOI: 10.4103/1673-5374.339488
  
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journals.lww.com/nrronline/Fulltext/2022/12000/Necrostatin_1_decreases_necroptosis_and.37.aspx
Dec 2021
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BPS Publications

1
1. scibot 21 Dec 2021
  
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  RRID:AB_2687465
  
  DOI: 10.1111/bph.15702
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15702
Nov 2021
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Identification of early-onset photoreceptor degeneration in transgenic mouse models of Alzheimer's disease

1
1. scibot 09 Nov 2021
  
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  RRID:AB_2687465
  
  DOI: 10.1016/j.isci.2021.103327
  
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Oct 2021
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Promyelocytic leukemia protein targets MK2 to promote cytotoxicity

1
1. scibot 12 Oct 2021
  
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  RRID:AB_2687465
  
  DOI: 10.15252/embr.202052254
  
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Aug 2021
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Autophagy regulates inflammatory programmed cell death via turnover of RHIM-domain proteins

1
1. scibot 14 Aug 2021
  
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  RRID:AB_2687465
  
  DOI: 10.7554/eLife.44452
  
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Untitled document

1
1. scibot 03 Aug 2021
  
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  RRID:AB_2687465
  
  DOI: 10.1016/j.ebiom.2018.10.017
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6286641/
Jun 2021
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Vaccinia virus E3 prevents sensing of Z-RNA to block ZBP1-dependent necroptosis

1
1. scibot 30 Jun 2021
  
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  RRID:AB_2687465
  
  DOI: 10.1016/j.chom.2021.05.009
  
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sciencedirect.com/science/article/pii/S1931312821002377
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Streptococcus pneumoniae binds to host GAPDH on dying lung epithelial cells worsening secondary infection following influenza

1
1. scibot 16 Jun 2021
  
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  RRID:AB_2687465
  
  DOI: 10.1016/j.celrep.2021.109267
  
  Resource: (Abcam Cat# ab196436, RRID:AB_2687465)
  
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sciencedirect.com/science/article/pii/S2211124721006343
May 2021
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RIPK1 activation mediates neuroinflammation and disease progression in multiple sclerosis

1
1. scibot 12 May 2021
  
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  RRID:AB_2687465
  
  DOI: 10.1016/j.celrep.2021.109112
  
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A Non-canonical PDK1-RSK Signal Diminishes Pro-caspase-8-Mediated Necroptosis Blockade

1
1. scibot 08 May 2021
  
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  RRID:AB_2687465
  
  DOI: 10.1016/j.molcel.2020.09.004
  
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A class of viral inducer of degradation of the necroptosis adaptor RIPK3 regulates virus-induced inflammation

1
1. scibot 07 May 2021
  
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  RRID:AB_2687465
  
  DOI: 10.1016/j.immuni.2020.11.020
  
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Apr 2021
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Inhibition of MLKL-dependent necroptosis via downregulating interleukin-1R1 contributes to neuroprotection of hypoxic preconditioning in transient global cerebral ischemic rats

1
1. scibot 22 Apr 2021
  
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  RRID:AB_2687465
  
  DOI: 10.1186/s12974-021-02141-y
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8056617/
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The multitargeted kinase inhibitor KW-2449 ameliorates cisplatin-induced nephrotoxicity by targeting RIPK1-mediated necroptosis

1
1. scibot 06 Apr 2021
  
  in Public
  
  anti-mouse phospho-MLKL
  
  DOI: 10.1016/j.bcp.2021.114542
  
  Resource: (Abcam Cat# ab196436, RRID:AB_2687465)
  
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Nov 2020
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Casein kinase 1G2 suppresses necroptosis-promoted testis aging by inhibiting receptor-interacting kinase 3

1
1. scibot 26 Nov 2020
  
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  RRID:AB_2687465
  
  DOI: 10.7554/eLife.61564
  
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G9a Promotes Breast Cancer Recurrence through Repression of a Pro-inflammatory Program

1
1. scibot 12 Nov 2020
  
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  RRID:AB_2687465
  
  DOI: 10.1016/j.celrep.2020.108341
  
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Sep 2020
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Influenza Virus Z-RNAs Induce ZBP1-Mediated Necroptosis

1
1. scibot 23 Sep 2020
  
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  RRID:AB_2687465
  
  DOI: 10.1016/j.cell.2020.02.050
  
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The Autophagy-Initiating Kinase ULK1 Controls RIPK1-Mediated Cell Death

1
1. scibot 16 Sep 2020
  
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  RRID:AB_2687465
  
  DOI: 10.1016/j.celrep.2020.107547
  
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Dysregulated Expression of the Nuclear Exosome Targeting Complex Component Rbm7 in Nonhematopoietic Cells Licenses the Development of Fibrosis

1
1. scibot 16 Sep 2020
  
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  RRID:AB_2687465
  
  DOI: 10.1016/j.immuni.2020.02.007
  
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Flexible Usage and Interconnectivity of Diverse Cell Death Pathways Protect against Intracellular Infection

1
1. scibot 04 Sep 2020
  
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  RRID:AB_2687465
  
  DOI: 10.1016/j.immuni.2020.07.004
  
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sciencedirect.com/science/article/pii/S1074761320302843
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Constitutive Interferon Attenuates RIPK1/3-Mediated Cytokine Translation

1
1. scibot 03 Sep 2020
  
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  RRID:AB_2687465
  
  DOI: 10.1016/j.celrep.2019.12.073
  
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sciencedirect.com/science/article/pii/S2211124719317309
Jan 2020
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RIPK3 Activation Leads to Cytokine Synthesis that Continues after Loss of Cell Membrane Integrity

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2687465
  
  DOI: 10.1016/j.celrep.2019.07.077
  
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O-GlcNAc Transferase Suppresses Inflammation and Necroptosis by Targeting Receptor-Interacting Serine/Threonine-Protein Kinase 3

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2687465
  
  DOI: 10.1016/j.immuni.2019.01.007
  
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bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

Untitled document

1
1. scibot 13 Jan 2020
  
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  RRID:AB_2687465
  
  DOI: 10.1111/bph.14653
  
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bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.14653
www.jneurosci.org www.jneurosci.org

Axonal Degeneration Is Mediated by Necroptosis Activation

1
1. scibot 12 Jan 2020
  
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  RRID:AB_2687465
  
  DOI: 10.1523/JNEUROSCI.0881-18.2019
  
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jneurosci.org/content/39/20/3832
Nov 2017
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MLKL, the Protein that Mediates Necroptosis, Also Regulates Endosomal Trafficking and Extracellular Vesicle Generation

1
1. scibot 08 Nov 2017
  
  in Public
  
  Rabbit anti-mouse MLKL (phospho S345), Clone EPR9515(2)AbcamCat# ab196436
  
  Curator: @Jmenke
  
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  (Abcam Cat# ab196436, RRID:AB_2687465)
  
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sciencedirect.com/science/article/pii/S1074761317302285