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  1. Last 7 days
  2. www.sciencedirect.com www.sciencedirect.com
    Unraveling ETC complex I function in ferroptosis reveals a potential ferroptosis-inducing therapeutic strategy for LKB1-deficient cancers
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    1. scibot 17 May 2024
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      DOI: 10.1016/j.molcel.2024.04.009

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    sciencedirect.com/science/article/pii/S1097276524003241
  3. Mar 2024
  4. www.sciencedirect.com www.sciencedirect.com
    ATF4-SLC7A11-GSH axis mediates the acquisition of immunosuppressive properties by activated CD4+ T cells in low arginine condition
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    1. scibot 27 Mar 2024
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      DOI: 10.1016/j.celrep.2024.113995

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    sciencedirect.com/science/article/pii/S2211124724003231
  5. Jan 2024
  6. www.science.org www.science.org
    Proximity proteomic analysis of the NRF family reveals the Parkinson’s disease protein ZNF746/PARIS as a co-complexed repressor of NRF2
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    1. scibot 12 Jan 2024
      RRID:AB_2687474

      DOI: 10.1126/scisignal.adi9018

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    science.org/doi/10.1126/scisignal.adi9018
  7. Dec 2023
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TXNDC12 inhibits lipid peroxidation and ferroptosis
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    1. scibot 06 Dec 2023
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      DOI: 10.1016/j.isci.2023.108393

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    ncbi.nlm.nih.gov/pmc/articles/PMC10690572/
  9. www.sciencedirect.com www.sciencedirect.com
    SMURF2 predisposes cancer cell toward ferroptosis in GPX4-independent manners by promoting GSTP1 degradation
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    1. scibot 01 Dec 2023
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      DOI: 10.1016/j.molcel.2023.10.042

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    sciencedirect.com/science/article/pii/S1097276523009139
  10. Oct 2023
  11. www.cell.com www.cell.com
    AMER1 deficiency promotes the distant metastasis of colorectal cancer by inhibiting SLC7A11- and FTL-mediated ferroptosis
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    1. scibot 06 Oct 2023
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      DOI: 10.1016/j.celrep.2023.113110

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    cell.com/cell-reports/abstract/S2211-1247(23)01121-X
  12. Aug 2023
  13. 52.53.155.43 52.53.155.43
    HIF-1α drives resistance to ferroptosis in solid tumors by promoting lactate production and activating SLC1A1
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    1. scibot 12 Aug 2023
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      DOI: 10.1016/j.celrep.2023.112945

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    2. scibot 05 Aug 2023
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      DOI: 10.1016/j.celrep.2023.112945

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    52.53.155.43/a33688970e7ada6a5acbf8256b00bc51e343dfea/PIIS2211124723009567-html.html
  14. Jul 2023
  15. www.sciencedirect.com www.sciencedirect.com
    The integrated stress response effector ATF4 is an obligatory metabolic activator of NRF2
    1
    1. scibot 07 Jul 2023
      RRID:AB_2687474

      DOI: 10.1016/j.celrep.2023.112724

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    sciencedirect.com/science/article/pii/S2211124723007350
  16. Jun 2023
  17. www.sciencedirect.com www.sciencedirect.com
    Modulation of cellular metabolism by protein crotonylation regulates pancreatic cancer progression
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    1. scibot 24 Jun 2023
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      DOI: 10.1016/j.celrep.2023.112666

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    sciencedirect.com/science/article/pii/S2211124723006770
  18. May 2023
  19. www.sciencedirect.com www.sciencedirect.com
    IL-1β-associated NNT acetylation orchestrates iron-sulfur cluster maintenance and cancer immunotherapy resistance
    1
    1. scibot 31 May 2023
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      DOI: 10.1016/j.molcel.2023.05.011

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    sciencedirect.com/science/article/pii/S1097276523003350
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Reprogramming of Iron Metabolism Confers Ferroptosis Resistance in ECM-Detached Cells
    1
    1. scibot 27 May 2023
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      DOI: 10.1016/j.isci.2023.106827

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    ncbi.nlm.nih.gov/pmc/articles/PMC10209538/
  21. Oct 2022
  22. elifesciences.org elifesciences.org
    GCN2 eIF2 kinase promotes prostate cancer by maintaining amino acid homeostasis
    1
    1. scibot 19 Oct 2022
      RRID:AB_2687474

      DOI: 10.7554/eLife.81083

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    elifesciences.org/articles/81083
  23. Apr 2022
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Stem cell factor SOX2 confers ferroptosis resistance in lung cancer via upregulation of SLC7A11
    1
    1. scibot 16 Apr 2022
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      DOI: 10.1158/0008-5472.CAN-21-0567

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    ncbi.nlm.nih.gov/pmc/articles/PMC8530936/
  25. Mar 2022
  26. www.sciencedirect.com www.sciencedirect.com
    Kynurenine importation by SLC7A11 propagates anti-ferroptotic signaling
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    1. scibot 04 Mar 2022
      RRID:AB_2687474

      DOI: 10.1016/j.molcel.2022.02.007

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    sciencedirect.com/science/article/pii/S1097276522001125
  27. Jan 2022
  28. www.sciencedirect.com www.sciencedirect.com
    Metabolic diversity within breast cancer brain-tropic cells determines metastatic fitness
    1
    1. scibot 05 Jan 2022
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      DOI: 10.1016/j.cmet.2021.12.001

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    sciencedirect.com/science/article/pii/S1550413121006203
  29. Dec 2021
  30. www.sciencedirect.com www.sciencedirect.com
    Redox-sensitive cyclophilin A elicits chemoresistance through realigning cellular oxidative status in colorectal cancer
    1
    1. scibot 01 Dec 2021
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      DOI: 10.1016/j.celrep.2021.110069

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    sciencedirect.com/science/article/pii/S2211124721015552
  31. Jun 2021
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    KEAP1 deficiency drives glucose dependency and sensitizes lung cancer cells and tumors to GLUT inhibition
    1
    1. scibot 22 Jun 2021
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      DOI: 10.1016/j.isci.2021.102649

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    ncbi.nlm.nih.gov/pmc/articles/PMC8193145/
  33. May 2021
  34. www.sciencedirect.com www.sciencedirect.com
    Signals of pseudo-starvation unveil the amino acid transporter SLC7A11 as key determinant in the control of Treg cell proliferative potential
    1
    1. scibot 18 May 2021
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      DOI: 10.1016/j.immuni.2021.04.014

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    sciencedirect.com/science/article/pii/S107476132100176X
  35. Apr 2021
  36. link.springer.com link.springer.com
    Glutamine deficiency promotes stemness and chemoresistance in tumor cells through DRP1-induced mitochondrial fragmentation
    1
    1. scibot 29 Apr 2021
      RRID:AB_2687474

      DOI: 10.1007/s00018-021-03818-6

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    link.springer.com/article/10.1007/s00018-021-03818-6
  37. www.sciencedirect.com www.sciencedirect.com
    Integrated Metabolic and Epigenomic Reprograming by H3K27M Mutations in Diffuse Intrinsic Pontine Gliomas
    1
    1. scibot 20 Apr 2021
      RRID:AB_2687474

      DOI: 10.1016/j.ccell.2020.07.008

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    sciencedirect.com/science/article/pii/S153561082030369X
  38. www.cell.com www.cell.com
    Loss of LUC7L2 and U1 snRNP subunits shifts energy metabolism from glycolysis to OXPHOS
    1
    1. scibot 14 Apr 2021
      RRID:AB_2687474

      DOI: 10.1016/j.molcel.2021.02.033

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    cell.com/molecular-cell/fulltext/S1097-2765(21)00143-X
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The mTORC1-mediated activation of ATF4 promotes protein and glutathione synthesis downstream of growth signals
    1
    1. scibot 06 Apr 2021
      RRID:AB_2687474

      DOI: 10.7554/eLife.63326

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    ncbi.nlm.nih.gov/pmc/articles/PMC7997658/
  40. Dec 2020
  41. www.sciencedirect.com www.sciencedirect.com
    HCAR1/MCT1 Regulates Tumor Ferroptosis through the Lactate-Mediated AMPK-SCD1 Activity and Its Therapeutic Implications
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    1. scibot 13 Dec 2020
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      DOI: 10.1016/j.celrep.2020.108487

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    sciencedirect.com/science/article/pii/S2211124720314765
  42. Jan 2020
  43. www.sciencedirect.com www.sciencedirect.com
    Transsulfuration Activity Can Support Cell Growth upon Extracellular Cysteine Limitation
    1
    1. scibot 13 Jan 2020
      RRID:AB_2687474

      DOI: 10.1016/j.cmet.2019.09.009

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    sciencedirect.com/science/article/pii/S1550413119305121
  44. www.sciencedirect.com www.sciencedirect.com
    Liver-Type Glutaminase GLS2 Is a Druggable Metabolic Node in Luminal-Subtype Breast Cancer
    1
    1. scibot 13 Jan 2020
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      DOI: 10.1016/j.celrep.2019.08.076

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    sciencedirect.com/science/article/pii/S2211124719311313
  45. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 13 Jan 2020
      RRID:AB_2687474

      DOI: 10.1016/j.ccell.2018.12.009

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    sciencedirect.com/science/article/pii/S1535610818305816
  46. Nov 2018
  47. www.sciencedirect.com www.sciencedirect.com
    AMPK-Mediated BECN1 Phosphorylation Promotes Ferroptosis by Directly Blocking System Xc– Activity
    1
    1. scibot 05 Nov 2018
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    sciencedirect.com/science/article/pii/S0960982218307644
  48. www.sciencedirect.com www.sciencedirect.com
    Oncogenic KRAS Regulates Amino Acid Homeostasis and Asparagine Biosynthesis via ATF4 and Alters Sensitivity to L-Asparaginase
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    1. scibot 05 Nov 2018
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    sciencedirect.com/science/article/pii/S153561081730555X
  49. www.sciencedirect.com www.sciencedirect.com
    NRF2 Is a Major Target of ARF in p53-Independent Tumor Suppression
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    1. scibot 05 Nov 2018
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    sciencedirect.com/science/article/pii/S1097276517306573
  50. Nov 2017
  51. www.sciencedirect.com www.sciencedirect.com
    mTORC2 Regulates Amino Acid Metabolism in Cancer by Phosphorylation of the Cystine-Glutamate Antiporter xCT
    1
    1. scibot 08 Nov 2017
      Rabbit Monoclonal anti-xCT/SLC7A11, Clone D2M7ACell SignalingCat#12691

      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S1097276517303945