66 Matching Annotations
  1. Nov 2024
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Clopidogrel ameliorates high-fat diet-induced hepatic steatosis in mice through activation of the AMPK signaling pathway and beyond
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    1. scibot 10 Nov 2024
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      DOI: 10.3389/fphar.2024.1496639

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    pmc.ncbi.nlm.nih.gov/articles/PMC11537861/
  3. Sep 2024
  4. www.sciencedirect.com www.sciencedirect.com
    Crosstalk between butyrate oxidation in colonocyte and butyrate-producing bacteria
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    1. scibot 13 Sep 2024
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    sciencedirect.com/science/article/pii/S2589004224020789
  5. Aug 2024
  6. www.cell.com www.cell.com
    Growth differentiation factor 15 alleviates diastolic dysfunction in mice with experimental diabetic cardiomyopathy
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    1. scibot 18 Aug 2024
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    cell.com/cell-reports/abstract/S2211-1247(24)00902-1
  7. May 2024
  8. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Monocarboxylate transporter 4 deficiency enhances high-intensity interval training-induced metabolic adaptations in skeletal muscle
    1
    1. scibot 24 May 2024
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      DOI: 10.1113/JP285719

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    physoc.onlinelibrary.wiley.com/doi/10.1113/JP285719
  9. journals.physiology.org journals.physiology.org
    ajpcell.00718.2023.pdf
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    1. scibot 09 May 2024
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    journals.physiology.org/doi/pdfdirect/10.1152/ajpcell.00718.2023
  10. Apr 2024
  11. www.sciencedirect.com www.sciencedirect.com
    Endothelial progenitor cells control remodeling of uterine spiral arteries for the establishment of utero-placental circulation
    1
    1. scibot 25 Apr 2024
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      DOI: 10.1016/j.devcel.2024.04.009

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    sciencedirect.com/science/article/pii/S153458072400234X
  12. www.sciencedirect.com www.sciencedirect.com
    25-Hydroxycholesterol regulates lysosome AMP kinase activation and metabolic reprogramming to educate immunosuppressive macrophages
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    1. scibot 19 Apr 2024
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      DOI: 10.1016/j.immuni.2024.03.021

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    sciencedirect.com/science/article/pii/S1074761324001420
  13. Mar 2024
  14. www.sciencedirect.com www.sciencedirect.com
    Acetyl-CoA carboxylase obstructs CD8+ T cell lipid utilization in the tumor microenvironment
    2
    1. scibot 15 Mar 2024
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    2. scibot 15 Mar 2024
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    sciencedirect.com/science/article/pii/S155041312400055X
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    PKM2 diverts glycolytic flux in dependence on mitochondrial one-carbon cycle
    1
    1. scibot 01 Mar 2024
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    sciencedirect.com/science/article/pii/S2211124724001967
  16. Jan 2024
  17. www.mdpi.com www.mdpi.com
    BAY-3827 and SBI-0206965: Potent AMPK Inhibitors That Paradoxically Increase Thr172 Phosphorylation
    1
    1. scibot 07 Jan 2024
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      DOI: 10.3390/ijms25010453

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    mdpi.com/1422-0067/25/1/453
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Frequent loss-of-function mutations in the AMPK-α2 catalytic subunit suggest a tumour suppressor role in human skin cancers
    1
    1. scibot 05 Jan 2024
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      DOI: 10.1042/BCJ20230380

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    ncbi.nlm.nih.gov/pmc/articles/PMC10754287/
  19. Nov 2023
  20. www.sciencedirect.com www.sciencedirect.com
    A bacteria-derived tetramerized protein ameliorates nonalcoholic steatohepatitis in mice via binding and relocating acetyl-coA carboxylase
    1
    1. scibot 28 Nov 2023
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    sciencedirect.com/science/article/pii/S2211124723014651
  21. Sep 2023
  22. www.sciencedirect.com www.sciencedirect.com
    Molecular, metabolic, and functional CD4 T cell paralysis in the lymph node impedes tumor control
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    sciencedirect.com/science/article/pii/S2211124723010586
  23. Aug 2023
  24. 52.53.155.43 52.53.155.43
    PIIS2589004223017029-html.html
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    1. scibot 18 Aug 2023
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      DOI: 10.1016/j.isci.2023.107625

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    52.53.155.43/258d74bd1c79cf4d725c254c0f9188b69c056c90/PIIS2589004223017029-html.html
  25. May 2023
  26. www.sciencedirect.com www.sciencedirect.com
    ATROPHIC REMODELING OF THE HEART DURING VITAMIN D DEFICIENCY AND INSUFFICIENCY IN A RAT MODEL
    1
    1. scibot 20 May 2023
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      DOI: 10.1016/j.jnutbio.2023.109382

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    sciencedirect.com/science/article/pii/S0955286323001158
  27. Apr 2023
  28. www.sciencedirect.com www.sciencedirect.com
    Senomorphic effect of diphenyleneiodonium through AMPK/MFF/DRP1 mediated mitochondrial fission
    1
    1. scibot 04 Apr 2023
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      DOI: 10.1016/j.biopha.2023.114616

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    sciencedirect.com/science/article/pii/S0753332223004043
  29. Mar 2023
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activation of AMP-activated protein kinase (AMPK) through inhibiting interaction with prohibitins
    1
    1. scibot 22 Mar 2023
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      DOI: 10.1016/j.isci.2023.106293

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    ncbi.nlm.nih.gov/pmc/articles/PMC10025096/
  31. Jan 2023
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    AMPK is required for recovery from metabolic stress induced by ultrasound microbubble treatment
    1
    1. scibot 20 Jan 2023
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      DOI: 10.1016/j.isci.2022.105883

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    ncbi.nlm.nih.gov/pmc/articles/PMC9845798/
  33. Nov 2022
  34. www.cell.com www.cell.com
    Downregulation of hepatic ceruloplasmin ameliorates NAFLD via SCO1-AMPK-LKB1 complex
    1
    1. scibot 10 Nov 2022
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      DOI: 10.1016/j.celrep.2022.111498

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    cell.com/cell-reports/abstract/S2211-1247(22)01348-1
  35. Aug 2022
  36. www.sciencedirect.com www.sciencedirect.com
    The AMPK-HOXB9-KRAS axis regulates lung adenocarcinoma growth in response to cellular energy alterations
    1
    1. scibot 26 Aug 2022
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      DOI: 10.1016/j.celrep.2022.111210

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    sciencedirect.com/science/article/pii/S2211124722010270
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    Genetic impairment of succinate metabolism disrupts bioenergetic sensing in adrenal neuroendocrine cancer
    1
    1. scibot 17 Aug 2022
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      DOI: 10.1016/j.celrep.2022.111218

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    sciencedirect.com/science/article/pii/S221112472201035X
  38. Jul 2022
  39. www.sciencedirect.com www.sciencedirect.com
    Pathological mitophagy disrupts mitochondrial homeostasis in Leber’s hereditary optic neuropathy
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    1. scibot 27 Jul 2022
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      DOI: 10.1016/j.celrep.2022.111124

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    sciencedirect.com/science/article/pii/S2211124722009305
  40. Jun 2022
  41. www.sciencedirect.com www.sciencedirect.com
    Itaconate is a lysosomal inducer that promotes antibacterial innate immunity
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    1. scibot 08 Jun 2022
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      DOI: 10.1016/j.molcel.2022.05.009

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    sciencedirect.com/science/article/pii/S1097276522004439
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Astilbin Activates the Reactive Oxidative Species/PPARγ Pathway to Suppress Effector CD4+ T Cell Activities via Direct Binding With Cytochrome P450 1B1
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    1. scibot 01 Jun 2022
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      DOI: 10.3389/fphar.2022.848957

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    ncbi.nlm.nih.gov/pmc/articles/PMC9150850/
  43. Apr 2022
  44. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    1. scibot 28 Apr 2022
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      DOI: 10.1111/bph.15837

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15837
  45. aacrjournals.org aacrjournals.org
    Lactate rewires lipid metabolism and sustains a metabolic-epigenetic axis in prostate cancer
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    1. scibot 05 Apr 2022
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      DOI: 10.1158/0008-5472.CAN-21-0914

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    aacrjournals.org/cancerres/article/82/7/1267/694059/Lactate-Rewires-Lipid-Metabolism-and-Sustains-a
  46. Dec 2021
  47. reader.elsevier.com reader.elsevier.com
    Lysophosphatidic acid shifts metabolic and transcriptional landscapes to induce a distinct cellular state in human pluripotent stem cells
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      DOI: 10.1016/j.celrep.2021.110063

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    reader.elsevier.com/reader/sd/pii/S2211124721015497
  48. Nov 2021
  49. www.sciencedirect.com www.sciencedirect.com
    TM4SF5-dependent crosstalk between hepatocytes and macrophages to reprogram the inflammatory environment
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    1. scibot 17 Nov 2021
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      DOI: 10.1016/j.celrep.2021.110018

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    sciencedirect.com/science/article/pii/S221112472101500X
  50. Oct 2021
  51. www.sciencedirect.com www.sciencedirect.com
    Inhibition of glucose transport synergizes with chemical or genetic disruption of mitochondrial metabolism and suppresses TCA cycle-deficient tumors
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    1. scibot 29 Oct 2021
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      DOI: 10.1016/j.chembiol.2021.10.007

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    sciencedirect.com/science/article/pii/S2451945621004414
  52. Aug 2021
  53. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 07 Aug 2021
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      DOI: 10.1016/j.celrep.2019.03.067

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    sciencedirect.com/science/article/pii/S2211124719303973
  54. Jul 2021
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    1. scibot 31 Jul 2021
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      DOI: 10.1016/j.celrep.2018.07.101

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    ncbi.nlm.nih.gov/pmc/articles/PMC6298213/
  56. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Arctigenin improves lipid metabolism by regulating AMP‐activated protein kinase and downstream signaling pathways
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    1. scibot 28 Jul 2021
      phosphou2010ACC (Ser79)

      DOI: 10.1002/jcb.28602

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    onlinelibrary.wiley.com/doi/full/10.1002/jcb.28602
  57. Jun 2021
  58. www.sciencedirect.com www.sciencedirect.com
    Choline kinase alpha 2 acts as a protein kinase to promote lipolysis of lipid droplets
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    sciencedirect.com/science/article/pii/S1097276521003622
  59. May 2021
  60. www.sciencedirect.com www.sciencedirect.com
    A PKD-MFF signaling axis couples mitochondrial fission to mitotic progression
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      DOI: 10.1016/j.celrep.2021.109129

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    sciencedirect.com/science/article/pii/S221112472100468X
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    Transient phases of OXPHOS inhibitor resistance reveal underlying metabolic heterogeneity in single cells
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      DOI: 10.1016/j.cmet.2021.01.014

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    sciencedirect.com/science/article/pii/S1550413121000140
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    The ZMYND8-regulated mevalonate pathway endows YAP-high intestinal cancer with metabolic vulnerability
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      DOI: 10.1016/j.molcel.2021.04.009

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    sciencedirect.com/science/article/pii/S1097276521003142
  63. Apr 2021
  64. www.sciencedirect.com www.sciencedirect.com
    Energy status dictates PD-L1 protein abundance and anti-tumor immunity to enable checkpoint blockade
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      DOI: 10.1016/j.molcel.2021.03.037

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    sciencedirect.com/science/article/pii/S109727652100232X
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    SETD2 Restricts Prostate Cancer Metastasis by Integrating EZH2 and AMPK Signaling Pathways
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    1. scibot 17 Apr 2021
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      DOI: 10.1016/j.ccell.2020.05.022

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    sciencedirect.com/science/article/pii/S1535610820302725
  66. Mar 2021
  67. www.sciencedirect.com www.sciencedirect.com
    S1PR3–G12-biased agonist ALESIA targets cancer metabolism and promotes glucose starvation
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      RRID:AB_2687505

      DOI: 10.1016/j.chembiol.2021.01.004

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    sciencedirect.com/science/article/pii/S2451945621000040
  68. Feb 2021
  69. www.nature.com www.nature.com
    Metabolic conditioning of CD8 + effector T cells for adoptive cell therapy
    1
    1. scibot 26 Feb 2021
      anti-phospho-ACC1Ser79

      DOI: 10.1038/s42255-020-0256-z

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    nature.com/articles/s42255-020-0256-z
  70. bmcpulmmed.biomedcentral.com bmcpulmmed.biomedcentral.com
    Pulmonary inflammation-induced alterations in key regulators of mitophagy and mitochondrial biogenesis in murine skeletal muscle
    1
    1. scibot 19 Feb 2021
      RRID:AB_ 2,687,505

      DOI: 10.1186/s12890-020-1047-8

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    bmcpulmmed.biomedcentral.com/articles/10.1186/s12890-020-1047-8
  71. Sep 2020
  72. www.cell.com www.cell.com
    A Genome-wide ER-phagy Screen Highlights Key Roles of Mitochondrial Metabolism and ER-Resident UFMylation
    1
    1. scibot 23 Sep 2020
      RRID:AB_2687505

      DOI: 10.1016/j.cell.2020.02.017

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    cell.com/cell/fulltext/S0092-8674(20)30161-6
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    AMPK-dependent activation of the Cyclin Y/CDK16 complex controls autophagy
    1
    1. scibot 17 Sep 2020
      RRID:AB_2687505

      DOI: 10.1038/s41467-020-14812-0

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    ncbi.nlm.nih.gov/pmc/articles/PMC7042329/
  74. www.sciencedirect.com www.sciencedirect.com
    Mechanism of Activation of AMPK by Cordycepin
    1
    1. scibot 13 Sep 2020
      RRID:AB_2687505

      DOI: 10.1016/j.chembiol.2020.01.004

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  75. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
    1
    1. scibot 09 Sep 2020
      RRID:AB_2687505

      DOI: 10.1111/bph.14935

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.14935
  76. rupress.org rupress.org
    Genetic manipulation of LKB1 elicits lethal metastatic prostate cancer
    1
    1. scibot 04 Sep 2020
      phospho-ACC

      DOI: 10.1084/jem.20191787

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      SciCrunch record: RRID:AB_2687505

      Curator comments: Phospho-Acetyl-CoA Carboxylase (Ser79) (D7D11) Rabbit Antibody Cell Signaling Technology Cat# 11818

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    rupress.org/jem/article/217/6/e20191787/151590/Genetic-manipulation-of-LKB1-elicits-lethal
  77. Jan 2020
  78. www.sciencedirect.com www.sciencedirect.com
    Lactate Buildup at the Site of Chronic Inflammation Promotes Disease by Inducing CD4+ T Cell Metabolic Rewiring
    1
    1. scibot 13 Jan 2020
      RRID:AB_2687505

      DOI: 10.1016/j.cmet.2019.10.004

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    sciencedirect.com/science/article/pii/S1550413119305595
  79. www.sciencedirect.com www.sciencedirect.com
    PTPS Facilitates Compartmentalized LTBP1 S-Nitrosylation and Promotes Tumor Growth under Hypoxia
    1
    1. scibot 13 Jan 2020
      RRID:AB_2687505

      DOI: 10.1016/j.molcel.2019.09.018

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    sciencedirect.com/science/article/pii/S1097276519307233
  80. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
    1
    1. scibot 13 Jan 2020
      RRID:AB_2687505

      DOI: 10.1111/bph.14713

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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.14713
  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Immunometabolic Cross-Talk and Regulation of Endocrine and Metabolic Functions: Transgenic overexpression of CTRP3 prevents alcohol-induced hepatic triglyceride accumulation
    1
    1. scibot 13 Jan 2020
      AB_2687505

      DOI: 10.1152/ajpendo.00050.2018

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    ncbi.nlm.nih.gov/pmc/articles/PMC6415714/
  82. www.sciencedirect.com www.sciencedirect.com
    α-Ketoglutarate-Activated NF-κB Signaling Promotes Compensatory Glucose Uptake and Brain Tumor Development
    1
    1. scibot 13 Jan 2020
      RRID:AB_2687505

      DOI: 10.1016/j.molcel.2019.07.007

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    sciencedirect.com/science/article/pii/S1097276519305374
  83. www.sciencedirect.com www.sciencedirect.com
    γ-6-Phosphogluconolactone, a Byproduct of the Oxidative Pentose Phosphate Pathway, Contributes to AMPK Activation through Inhibition of PP2A
    1
    1. scibot 13 Jan 2020
      RRID:AB_2687505

      DOI: 10.1016/j.molcel.2019.09.007

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    sciencedirect.com/science/article/pii/S1097276519306926
  84. www.sciencedirect.com www.sciencedirect.com
    Mitochondrial Reprogramming Underlies Resistance to BCL-2 Inhibition in Lymphoid Malignancies
    1
    1. scibot 13 Jan 2020
      RRID:AB_2687505

      DOI: 10.1016/j.ccell.2019.08.005

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    sciencedirect.com/science/article/pii/S1535610819303733
  85. www.sciencedirect.com www.sciencedirect.com
    Untitled document
    1
    1. scibot 13 Jan 2020
      RRID:AB_2687505

      DOI: 10.1016/j.celrep.2019.01.062

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    sciencedirect.com/science/article/pii/S2211124719300919
  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
    1
    1. scibot 13 Jan 2020
      RRID:AB_2687505

      DOI: 10.1016/j.celrep.2019.03.067

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    ncbi.nlm.nih.gov/pmc/articles/PMC6484776/
  87. www.sciencedirect.com www.sciencedirect.com
    Untitled document
    1
    1. scibot 13 Jan 2020
      RRID:AB_2687505

      DOI: 10.1016/j.cmet.2019.02.002

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    sciencedirect.com/science/article/pii/S155041311930066X
  88. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 13 Jan 2020
      RRID:AB_2687505

      DOI: 10.1016/j.cmet.2019.01.024

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    sciencedirect.com/science/article/pii/S1550413119300646
  89. www.sciencedirect.com www.sciencedirect.com
    Genetic Analysis Reveals AMPK Is Required to Support Tumor Growth in Murine Kras-Dependent Lung Cancer Models
    1
    1. scibot 12 Jan 2020
      RRID:AB_2687505

      DOI: 10.1016/j.cmet.2018.10.005

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    sciencedirect.com/science/article/pii/S1550413118306375
  90. Nov 2018
  91. www.sciencedirect.com www.sciencedirect.com
    Untitled document
    1
    1. scibot 05 Nov 2018
      RRID:AB_2687505

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    sciencedirect.com/science/article/pii/S2211124718312348
  92. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Combined treatment with GSNO and CAPE accelerates functional recovery via additive antioxidant activities in a mouse model of TBI
    1
    1. scibot 05 Nov 2018
      RRID:AB_2687505

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    onlinelibrary.wiley.com/doi/full/10.1002/jnr.24279
  93. www.sciencedirect.com www.sciencedirect.com
    The PLAG1-GDH1 Axis Promotes Anoikis Resistance and Tumor Metastasis through CamKK2-AMPK Signaling in LKB1-Deficient Lung Cancer
    1
    1. scibot 05 Nov 2018
      RRID:AB_2687505

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    sciencedirect.com/science/article/pii/S1097276517308845
  94. europepmc.org europepmc.org
    Untitled document
    1
    1. scibot 05 Nov 2018
      RRID:AB_2687505

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    europepmc.org/articles/PMC5730373/
  95. Nov 2017
  96. www.sciencedirect.com www.sciencedirect.com
    Phosphoglycerate Kinase 1 Phosphorylates Beclin1 to Induce Autophagy
    1
    1. scibot 08 Nov 2017
      11818S

      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S1097276517300539
  97. www.sciencedirect.com www.sciencedirect.com
    The Mammalian Malonyl-CoA Synthetase ACSF3 Is Required for Mitochondrial Protein Malonylation and Metabolic Efficiency
    1
    1. scibot 08 Nov 2017
      Phospho-acetyl-CoA carboxylase (ACC) (Ser79), rabbit polyclonalCell SignalingCat#11818

      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S2451945617301095
  98. www.sciencedirect.com www.sciencedirect.com
    Mechanisms of Paradoxical Activation of AMPK by the Kinase Inhibitors SU6656 and Sorafenib
    1
    1. scibot 08 Nov 2017
      pACC1/pACC2 (S79/S212)Cell Signaling TechnologyCat# 11818

      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S2451945617301848