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High matrix stiffness triggers testosterone decline in aging males by disrupting stem Leydig cell pool homeostasis

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  DOI: 10.1016/j.celrep.2025.116207
  
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sciencedirect.com/science/article/pii/S2211124725009787
Aug 2025
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Adenosine kinase and ADAL coordinate detoxification of modified adenosines to safeguard metabolism

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  DOI: 10.1016/j.cell.2025.07.041
  
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sciencedirect.com/science/article/pii/S0092867425008633
May 2025
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KRAS G12V mutation-selective requirement for ACSS2 in colorectal adenoma formation

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  DOI: 10.1016/j.celrep.2025.115444
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12091147/
Mar 2025
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The nuclear pore complex connects energy sensing to transcriptional plasticity in longevity

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  DOI: 10.1101/2025.02.17.638704
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11870510/
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Dietary timing enhances exercise by modulating fat-muscle crosstalk via adipocyte AMPKα2 signaling

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Therapeutic assessment of a novel mitochondrial complex I inhibitor in in vitro and in vivo models of Alzheimer’s disease

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  DOI: 10.1101/2025.02.12.637918
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11870434/
Feb 2025
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USP5 stabilizes YTHDF1 to control cancer immune surveillance through mTORC1-mediated phosphorylation

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  DOI: 10.1038/s41467-025-56564-9
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11791202/
Jan 2025
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Mitochondrial uncouplers inhibit oncogenic E2F1 activity and prostate cancer growth

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  DOI: 10.1016/j.xcrm.2024.101890
  
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sciencedirect.com/science/article/pii/S266637912400661X
Nov 2024
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Clopidogrel ameliorates high-fat diet-induced hepatic steatosis in mice through activation of the AMPK signaling pathway and beyond

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pmc.ncbi.nlm.nih.gov/articles/PMC11537861/
Sep 2024
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Crosstalk between butyrate oxidation in colonocyte and butyrate-producing bacteria

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sciencedirect.com/science/article/pii/S2589004224020789
Aug 2024
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Growth differentiation factor 15 alleviates diastolic dysfunction in mice with experimental diabetic cardiomyopathy

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cell.com/cell-reports/abstract/S2211-1247(24)00902-1
May 2024
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Monocarboxylate transporter 4 deficiency enhances high-intensity interval training-induced metabolic adaptations in skeletal muscle

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1. scibot 24 May 2024
  
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  DOI: 10.1113/JP285719
  
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physoc.onlinelibrary.wiley.com/doi/10.1113/JP285719
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ajpcell.00718.2023.pdf

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  DOI: 10.1152/ajpcell.00718.2023
  
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journals.physiology.org/doi/pdfdirect/10.1152/ajpcell.00718.2023
Apr 2024
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Endothelial progenitor cells control remodeling of uterine spiral arteries for the establishment of utero-placental circulation

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  DOI: 10.1016/j.devcel.2024.04.009
  
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sciencedirect.com/science/article/pii/S153458072400234X
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25-Hydroxycholesterol regulates lysosome AMP kinase activation and metabolic reprogramming to educate immunosuppressive macrophages

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1. scibot 19 Apr 2024
  
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  DOI: 10.1016/j.immuni.2024.03.021
  
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sciencedirect.com/science/article/pii/S1074761324001420
Mar 2024
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Acetyl-CoA carboxylase obstructs CD8+ T cell lipid utilization in the tumor microenvironment

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sciencedirect.com/science/article/pii/S155041312400055X
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PKM2 diverts glycolytic flux in dependence on mitochondrial one-carbon cycle

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  DOI: 10.1016/j.celrep.2024.113868
  
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sciencedirect.com/science/article/pii/S2211124724001967
Jan 2024
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BAY-3827 and SBI-0206965: Potent AMPK Inhibitors That Paradoxically Increase Thr172 Phosphorylation

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1. scibot 07 Jan 2024
  
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  DOI: 10.3390/ijms25010453
  
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mdpi.com/1422-0067/25/1/453
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Frequent loss-of-function mutations in the AMPK-α2 catalytic subunit suggest a tumour suppressor role in human skin cancers

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  DOI: 10.1042/BCJ20230380
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10754287/
Nov 2023
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A bacteria-derived tetramerized protein ameliorates nonalcoholic steatohepatitis in mice via binding and relocating acetyl-coA carboxylase

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sciencedirect.com/science/article/pii/S2211124723014651
Sep 2023
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Molecular, metabolic, and functional CD4 T cell paralysis in the lymph node impedes tumor control

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sciencedirect.com/science/article/pii/S2211124723010586
Aug 2023
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PIIS2589004223017029-html.html

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52.53.155.43/258d74bd1c79cf4d725c254c0f9188b69c056c90/PIIS2589004223017029-html.html
May 2023
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ATROPHIC REMODELING OF THE HEART DURING VITAMIN D DEFICIENCY AND INSUFFICIENCY IN A RAT MODEL

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  DOI: 10.1016/j.jnutbio.2023.109382
  
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sciencedirect.com/science/article/pii/S0955286323001158
Apr 2023
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Senomorphic effect of diphenyleneiodonium through AMPK/MFF/DRP1 mediated mitochondrial fission

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  DOI: 10.1016/j.biopha.2023.114616
  
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sciencedirect.com/science/article/pii/S0753332223004043
Mar 2023
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Activation of AMP-activated protein kinase (AMPK) through inhibiting interaction with prohibitins

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ncbi.nlm.nih.gov/pmc/articles/PMC10025096/
Jan 2023
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AMPK is required for recovery from metabolic stress induced by ultrasound microbubble treatment

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  DOI: 10.1016/j.isci.2022.105883
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9845798/
Nov 2022
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Downregulation of hepatic ceruloplasmin ameliorates NAFLD via SCO1-AMPK-LKB1 complex

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cell.com/cell-reports/abstract/S2211-1247(22)01348-1
Aug 2022
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The AMPK-HOXB9-KRAS axis regulates lung adenocarcinoma growth in response to cellular energy alterations

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sciencedirect.com/science/article/pii/S2211124722010270
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Genetic impairment of succinate metabolism disrupts bioenergetic sensing in adrenal neuroendocrine cancer

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sciencedirect.com/science/article/pii/S221112472201035X
Jul 2022
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Pathological mitophagy disrupts mitochondrial homeostasis in Leber’s hereditary optic neuropathy

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  DOI: 10.1016/j.celrep.2022.111124
  
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sciencedirect.com/science/article/pii/S2211124722009305
Jun 2022
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Itaconate is a lysosomal inducer that promotes antibacterial innate immunity

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  DOI: 10.1016/j.molcel.2022.05.009
  
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sciencedirect.com/science/article/pii/S1097276522004439
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Astilbin Activates the Reactive Oxidative Species/PPARγ Pathway to Suppress Effector CD4+ T Cell Activities via Direct Binding With Cytochrome P450 1B1

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  DOI: 10.3389/fphar.2022.848957
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9150850/
Apr 2022
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BPS Publications

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  DOI: 10.1111/bph.15837
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15837
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Lactate rewires lipid metabolism and sustains a metabolic-epigenetic axis in prostate cancer

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  DOI: 10.1158/0008-5472.CAN-21-0914
  
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aacrjournals.org/cancerres/article/82/7/1267/694059/Lactate-Rewires-Lipid-Metabolism-and-Sustains-a
Dec 2021
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Lysophosphatidic acid shifts metabolic and transcriptional landscapes to induce a distinct cellular state in human pluripotent stem cells

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TM4SF5-dependent crosstalk between hepatocytes and macrophages to reprogram the inflammatory environment

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Inhibition of glucose transport synergizes with chemical or genetic disruption of mitochondrial metabolism and suppresses TCA cycle-deficient tumors

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Arctigenin improves lipid metabolism by regulating AMP‐activated protein kinase and downstream signaling pathways

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Choline kinase alpha 2 acts as a protein kinase to promote lipolysis of lipid droplets

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A PKD-MFF signaling axis couples mitochondrial fission to mitotic progression

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Transient phases of OXPHOS inhibitor resistance reveal underlying metabolic heterogeneity in single cells

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The ZMYND8-regulated mevalonate pathway endows YAP-high intestinal cancer with metabolic vulnerability

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Energy status dictates PD-L1 protein abundance and anti-tumor immunity to enable checkpoint blockade

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SETD2 Restricts Prostate Cancer Metastasis by Integrating EZH2 and AMPK Signaling Pathways

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S1PR3–G12-biased agonist ALESIA targets cancer metabolism and promotes glucose starvation

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Metabolic conditioning of CD8 + effector T cells for adoptive cell therapy

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Pulmonary inflammation-induced alterations in key regulators of mitophagy and mitochondrial biogenesis in murine skeletal muscle

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A Genome-wide ER-phagy Screen Highlights Key Roles of Mitochondrial Metabolism and ER-Resident UFMylation

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AMPK-dependent activation of the Cyclin Y/CDK16 complex controls autophagy

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Mechanism of Activation of AMPK by Cordycepin

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BPS Publications

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Genetic manipulation of LKB1 elicits lethal metastatic prostate cancer

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Lactate Buildup at the Site of Chronic Inflammation Promotes Disease by Inducing CD4+ T Cell Metabolic Rewiring

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PTPS Facilitates Compartmentalized LTBP1 S-Nitrosylation and Promotes Tumor Growth under Hypoxia

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BPS Publications

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Immunometabolic Cross-Talk and Regulation of Endocrine and Metabolic Functions: Transgenic overexpression of CTRP3 prevents alcohol-induced hepatic triglyceride accumulation

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α-Ketoglutarate-Activated NF-κB Signaling Promotes Compensatory Glucose Uptake and Brain Tumor Development

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γ-6-Phosphogluconolactone, a Byproduct of the Oxidative Pentose Phosphate Pathway, Contributes to AMPK Activation through Inhibition of PP2A

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Mitochondrial Reprogramming Underlies Resistance to BCL-2 Inhibition in Lymphoid Malignancies

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Genetic Analysis Reveals AMPK Is Required to Support Tumor Growth in Murine Kras-Dependent Lung Cancer Models

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Combined treatment with GSNO and CAPE accelerates functional recovery via additive antioxidant activities in a mouse model of TBI

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The PLAG1-GDH1 Axis Promotes Anoikis Resistance and Tumor Metastasis through CamKK2-AMPK Signaling in LKB1-Deficient Lung Cancer

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  Curator: @evieth
  
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scibot

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europepmc.org/articles/PMC5730373/
Nov 2017
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Phosphoglycerate Kinase 1 Phosphorylates Beclin1 to Induce Autophagy

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1. scibot 08 Nov 2017
  
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  11818S
  
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sciencedirect.com/science/article/pii/S1097276517300539
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The Mammalian Malonyl-CoA Synthetase ACSF3 Is Required for Mitochondrial Protein Malonylation and Metabolic Efficiency

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1. scibot 08 Nov 2017
  
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  Phospho-acetyl-CoA carboxylase (ACC) (Ser79), rabbit polyclonalCell SignalingCat#11818
  
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sciencedirect.com/science/article/pii/S2451945617301095
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Mechanisms of Paradoxical Activation of AMPK by the Kinase Inhibitors SU6656 and Sorafenib

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1. scibot 08 Nov 2017
  
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  pACC1/pACC2 (S79/S212)Cell Signaling TechnologyCat# 11818
  
  Curator: @Jmenke
  
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  (Cell Signaling Technology Cat# 11818, RRID:AB_2687505)
  
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sciencedirect.com/science/article/pii/S2451945617301848

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