31 Matching Annotations
  1. Apr 2024
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HDAC10 inhibition represses melanoma cell growth and BRAF inhibitor resistance via upregulating SPARC expression
    1
    1. scibot 24 Apr 2024
      RRID:AB_2687578

      DOI: 10.1093/narcan/zcae018

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    ncbi.nlm.nih.gov/pmc/articles/PMC11034028/
  3. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    STAT3 couples activated tyrosine kinase signaling to the oncogenic core transcriptional regulatory circuitry of anaplastic large cell lymphoma
    1
    1. scibot 03 Apr 2024
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      DOI: 10.1016/j.xcrm.2024.101472

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    ncbi.nlm.nih.gov/pmc/articles/PMC10983107/
  4. Feb 2024
  5. www.sciencedirect.com www.sciencedirect.com
    A di-acetyl-decorated chromatin signature couples liquid condensation to suppress DNA end synapsis
    1
    1. scibot 29 Feb 2024
      RRID:AB_2687578

      DOI: 10.1016/j.molcel.2024.02.002

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    sciencedirect.com/science/article/pii/S1097276524000984
  6. www.sciencedirect.com www.sciencedirect.com
    Cullin-RING ligases employ geometrically optimized catalytic partners for substrate targeting
    1
    1. scibot 21 Feb 2024
      RRID:AB_2687578

      DOI: 10.1016/j.molcel.2024.01.022

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    sciencedirect.com/science/article/pii/S1097276524000893
  7. www.biorxiv.org www.biorxiv.org
    HDAC10 blockade upregulates SPARC expression thereby repressing melanoma cell growth and BRAF inhibitor resistance
    3
    1. scibot 09 Feb 2024
      RRID:AB_2687578

      DOI: 10.1101/2023.12.05.570182

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    2. scibot 09 Feb 2024
      RRID:AB_2687578

      DOI: 10.1101/2023.12.05.570182

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    3. scibot 09 Feb 2024
      RRID:AB_2687578

      DOI: 10.1101/2023.12.05.570182

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    biorxiv.org/content/10.1101/2023.12.05.570182v1
  8. www.sciencedirect.com www.sciencedirect.com
    The cyclimids: Degron-inspired cereblon binders for targeted protein degradation
    1
    1. scibot 06 Feb 2024
      RRID:AB_2687578

      DOI: 10.1016/j.chembiol.2024.01.003

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    sciencedirect.com/science/article/pii/S2451945624000394
  9. Nov 2023
  10. www.sciencedirect.com www.sciencedirect.com
    Super-enhancer trapping by the nuclear pore via intrinsically disordered regions of proteins in squamous cell carcinoma cells
    1
    1. scibot 28 Nov 2023
      RRID:AB_2687578

      DOI: 10.1016/j.chembiol.2023.10.005

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    sciencedirect.com/science/article/pii/S2451945623003665
  11. Oct 2023
  12. 52.53.155.43 52.53.155.43
    PIIS0092867423009650-html.html
    1
    1. scibot 06 Oct 2023
      RRID:AB_2687578

      DOI: 10.1016/j.cell.2023.08.032

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    52.53.155.43/10a4fc8c2567a3934d6a2c0730d82b14865b6e30/PIIS0092867423009650-html.html
  13. Jul 2023
  14. www.sciencedirect.com www.sciencedirect.com
    Distinct layers of BRD4-PTEFb reveal bromodomain-independent function in transcriptional regulation
    1
    1. scibot 13 Jul 2023
      RRID:AB_2687578

      DOI: 10.1016/j.molcel.2023.06.032

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    sciencedirect.com/science/article/abs/pii/S1097276523005087
  15. Apr 2023
  16. www.science.org www.science.org
    Targeting BRD3 eradicates nuclear TYRO3-induced colorectal cancer metastasis
    2
    1. scibot 20 Apr 2023
      RRID:AB_2687578

      DOI: 10.1126/sciadv.ade3422

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    2. scibot 14 Apr 2023
      RRID:AB_2687578

      DOI: 10.1126/sciadv.ade3422

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    science.org/doi/10.1126/sciadv.ade3422
  17. Feb 2023
  18. aacrjournals.org aacrjournals.org
    Loss of VOPP1 Contributes to BET Inhibitor Acquired Resistance in Non–Small Cell Lung Cancer Cells
    1
    1. scibot 18 Feb 2023
      RRID: AB_2687578

      DOI: 10.1158/1541-7786.MCR-21-1000

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    aacrjournals.org/mcr/article/20/12/1785/710999/Loss-of-VOPP1-Contributes-to-BET-Inhibitor
  19. Nov 2022
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cloning BRD4 long isoform into overexpression vectors for stable overexpression of BRD4-L in mammalian cells
    1
    1. scibot 02 Nov 2022
      RRID:AB_2687578

      DOI: 10.1016/j.xpro.2022.101785

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    ncbi.nlm.nih.gov/pmc/articles/PMC9617197/
  21. Sep 2022
  22. www.sciencedirect.com www.sciencedirect.com
    BET inhibition induces vulnerability to MCL1 targeting through upregulation of fatty acid synthesis pathway in breast cancer
    1
    1. scibot 15 Sep 2022
      RRID:AB_2687578

      DOI: 10.1016/j.celrep.2022.111304

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    sciencedirect.com/science/article/pii/S2211124722011287
  23. Jun 2022
  24. www.sciencedirect.com www.sciencedirect.com
    A direct high-throughput protein quantification strategy facilitates discovery and characterization of a celastrol-derived BRD4 degrader
    1
    1. scibot 03 Jun 2022
      RRID:AB_2687578

      DOI: 10.1016/j.chembiol.2022.05.003

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    sciencedirect.com/science/article/pii/S2451945622001659
  25. Mar 2022
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Profiling of diverse tumor types establishes the broad utility of VHL-based ProTaCs and triages candidate ubiquitin ligases
    1
    1. scibot 18 Mar 2022
      RRID:AB_2687578

      DOI: 10.1016/j.isci.2022.103985

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    ncbi.nlm.nih.gov/pmc/articles/PMC8919295/
  27. Feb 2022
  28. www.sciencedirect.com www.sciencedirect.com
    The landscape of pioneer factor activity reveals the mechanisms of chromatin reprogramming and genome activation
    1
    1. scibot 23 Feb 2022
      RRID:AB_2687578

      DOI: 10.1016/j.molcel.2022.01.024

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    sciencedirect.com/science/article/pii/S1097276522001009
  29. Sep 2021
  30. www.sciencedirect.com www.sciencedirect.com
    A strategy to assess the cellular activity of E3 ligase components against neo-substrates using electrophilic probes
    1
    1. scibot 09 Sep 2021
      RRID:AB_2687578

      DOI: 10.1016/j.chembiol.2021.08.007

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    sciencedirect.com/science/article/pii/S2451945621003962
  31. www.sciencedirect.com www.sciencedirect.com
    SPT5 stabilization of promoter-proximal RNA polymerase II
    1
    1. scibot 04 Sep 2021
      RRID:AB_2687578

      DOI: 10.1016/j.molcel.2021.08.006

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    sciencedirect.com/science/article/pii/S1097276521006468
  32. Aug 2021
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
    1
    1. scibot 09 Aug 2021
      RRID:AB_2687578

      DOI: 10.7554/eLife.39023

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    ncbi.nlm.nih.gov/pmc/articles/PMC6279352/
  34. www.nature.com www.nature.com
    Stromal induction of BRD4 phosphorylation Results in Chromatin Remodeling and BET inhibitor Resistance in Colorectal Cancer
    1
    1. scibot 05 Aug 2021
      RRID:AB_2687578

      DOI: 10.1038/s41467-021-24687-4

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    nature.com/articles/s41467-021-24687-4
  35. Mar 2021
  36. www.sciencedirect.com www.sciencedirect.com
    TRIP12 promotes small-molecule-induced degradation through K29/K48-branched ubiquitin chains
    1
    1. scibot 29 Mar 2021
      RRID:AB_2687578

      DOI: 10.1016/j.molcel.2021.01.023

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    sciencedirect.com/science/article/pii/S1097276521000435
  37. Jan 2020
  38. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Expression and clinical value of PD‐L1 which is regulated by BRD4 in tongue squamous cell carcinoma
    1
    1. scibot 13 Jan 2020
      RRID:AB_2687578

      DOI: 10.1002/jcb.29420

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    onlinelibrary.wiley.com/doi/10.1002/jcb.29420
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
    1
    1. scibot 13 Jan 2020
      RRID:AB_2687578

      DOI: 10.7554/eLife.41913

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    ncbi.nlm.nih.gov/pmc/articles/PMC6336405/
  40. Nov 2018
  41. www.sciencedirect.com www.sciencedirect.com
    Targeting Processive Transcription Elongation via SEC Disruption for MYC-Induced Cancer Therapy
    1
    1. scibot 05 Nov 2018
      RRID:AB_2687578

      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S009286741831239X
  42. www.sciencedirect.com www.sciencedirect.com
    Targeting Epigenetic Crosstalk as a Therapeutic Strategy for EZH2-Aberrant Solid Tumors
    1
    1. scibot 05 Nov 2018
      RRID:AB_2687578

      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S009286741831119X
  43. www.sciencedirect.com www.sciencedirect.com
    BRD4 Inhibition Is Synthetic Lethal with PARP Inhibitors through the Induction of Homologous Recombination Deficiency
    1
    1. scibot 05 Nov 2018
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    sciencedirect.com/science/article/pii/S1535610818300199
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Systematic Functional Annotation of Somatic Mutations in Cancer
    1
    1. scibot 05 Nov 2018
      RRID:AB_2687578

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    ncbi.nlm.nih.gov/pmc/articles/PMC5926201/
  45. Nov 2017
  46. www.sciencedirect.com www.sciencedirect.com
    Bromodomain Protein BRD4 Is a Transcriptional Repressor of Autophagy and Lysosomal Function
    1
    1. scibot 08 Nov 2017
      Rabbit monoclonal anti-BRD4 (clone E2A7X) (human specific) (long isoform)Cell Signaling TechnologyCat#: 13440S

      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S109727651730312X