101 Matching Annotations
  1. Last 7 days
  2. 52.53.155.43 52.53.155.43
    elife-92755-v2-html.html
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    1. scibot 13 Apr 2024
      AB_2687579

      DOI: 10.7554/elife.92755

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  3. Apr 2024
  4. pubs.rsc.org pubs.rsc.org
    Effectiveness of a novel gene nanotherapy based on putrescine for cancer treatment
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    1. scibot 05 Apr 2024
      9091, Cell Signaling Technology

      DOI: 10.1039/D2BM01456D

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    pubs.rsc.org/en/content/articlelanding/2023/bm/d2bm01456d
  5. Mar 2024
  6. www.sciencedirect.com www.sciencedirect.com
    Pooled CRISPR screening of high-content cellular phenotypes using ghost cytometry
    1
    1. scibot 29 Mar 2024
      AB_2687579

      DOI: 10.1016/j.crmeth.2024.100737

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  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Rho GTPase signaling and mDia facilitate endocytosis via presynaptic actin
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    1. scibot 22 Mar 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC10950329/
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    Cytosolic pH is a direct nexus in linking environmental cues with insulin processing and secretion in pancreatic β cells
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    1. scibot 21 Mar 2024
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    sciencedirect.com/science/article/pii/S1550413124000597
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    Lysosomal damage sensing and lysophagy initiation by SPG20-ITCH
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    1. scibot 19 Mar 2024
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    sciencedirect.com/science/article/pii/S1097276524001722
  10. Feb 2024
  11. www.sciencedirect.com www.sciencedirect.com
    In vivo CRISPR knockout screen identifies p47 as a suppressor of HER2+ breast cancer metastasis by regulating NEMO trafficking and autophagy flux
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    1. scibot 22 Feb 2024
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      DOI: 10.1016/j.celrep.2024.113780

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    sciencedirect.com/science/article/pii/S2211124724001086
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    Phospholipids with two polyunsaturated fatty acyl tails promote ferroptosis
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    1. scibot 16 Feb 2024
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    sciencedirect.com/science/article/pii/S0092867424000679
  13. Jan 2024
  14. www.sciencedirect.com www.sciencedirect.com
    ABCG2 is an itaconate exporter that limits antibacterial innate immunity by alleviating TFEB-dependent lysosomal biogenesis
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    1. scibot 11 Jan 2024
      RRID:AB_2687579

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    sciencedirect.com/science/article/pii/S1550413123004655
  15. Dec 2023
  16. www.sciencedirect.com www.sciencedirect.com
    Lysosomal dynamics regulate mammalian cortical neurogenesis
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    1. scibot 16 Dec 2023
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  17. elifesciences.org elifesciences.org
    Rab12 is a regulator of LRRK2 and its activation by damaged lysosomes
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    1. scibot 15 Dec 2023
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      DOI: 10.7554/eLife.87255

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    Nutrient-regulated control of lysosome function by signaling lipid conversion
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    1. scibot 02 Dec 2023
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    sciencedirect.com/science/article/pii/S0092867423010814
  19. Oct 2023
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Novel ASCT2 Inhibitor, C118P, Blocks Glutamine Transport and Exhibits Antitumour Efficacy in Breast Cancer
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    1. scibot 31 Oct 2023
      AB_2687579

      DOI: 10.3390/cancers15205082

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  21. 52.53.155.43 52.53.155.43
    mvad079-html.html
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    1. scibot 21 Oct 2023
      RRID:AB_2687579

      DOI: 10.1093/jb/mvad079

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  22. www.biorxiv.org www.biorxiv.org
    Linear ubiquitination at damaged lysosomes induces local NF-κB activation and controls cell survival
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    1. scibot 13 Oct 2023
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      DOI: 10.1101/2023.10.06.560832

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  23. 52.53.155.43 52.53.155.43
    s41586-023-06657-6_reference-html.html
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    1. scibot 06 Oct 2023
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      DOI: 10.1038/s41586-023-06657-6

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  24. Sep 2023
  25. www.embopress.org www.embopress.org
    CCDC50 promotes tumor growth through regulation of lysosome homeostasis
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      RRID: AB_2687579

      DOI: 10.15252/embr.202356948

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    Usp25-Erlin1/2 activity limits cholesterol flux to restrict virus infection
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    sciencedirect.com/science/article/pii/S1534580723004094
  27. Aug 2023
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Two RNA-binding proteins mediate the sorting of miR223 from mitochondria into exosomes
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    1. scibot 10 Aug 2023
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      DOI: 10.7554/eLife.85878

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    ncbi.nlm.nih.gov/pmc/articles/PMC10403255/
  29. www.sciencedirect.com www.sciencedirect.com
    Exosomal release of the virus-encoded chemokine receptor US28 contributes to chemokine scavenging
    1
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      RRID:AB_2687579

      DOI: 10.1016/j.isci.2023.107412

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    sciencedirect.com/science/article/pii/S258900422301489X
  30. Jul 2023
  31. 52.53.155.43 52.53.155.43
    A dual hit of α-synuclein internalization and immune challenge leads to formation and maintenance of Lewy body-like inclusions in human dopaminergic neurons
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    1. scibot 18 Jul 2023
      RRID:AB_2687579

      DOI: 10.1101/2023.05.29.542776

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    52.53.155.43/295724fe7577204c05a5e312c5e68d353e69e1f1/2023.05.29.542776v1.full-html.html
  32. Jun 2023
  33. www.sciencedirect.com www.sciencedirect.com
    Advanced human iPSC-based preclinical model for Parkinson’s disease with optogenetic alpha-synuclein aggregation
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    1. scibot 21 Jun 2023
      RRID:AB_2687579

      DOI: 10.1016/j.stem.2023.05.015

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    sciencedirect.com/science/article/pii/S1934590923002114
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Annexin A6 mediates calcium-dependent exosome secretion during plasma membrane repair
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    1. scibot 08 Jun 2023
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      DOI: 10.7554/eLife.86556

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    ncbi.nlm.nih.gov/pmc/articles/PMC10241516/
  35. aacrjournals.org aacrjournals.org
    Dysregulation of mitochondrial translation caused by CBFB deficiency cooperates with mutant PIK3CA and is a vulnerability in breast cancer
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    1. scibot 03 Jun 2023
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      DOI: 10.1158/0008-5472.CAN-22-2525

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    aacrjournals.org/cancerres/article/83/8/1280/725099/Dysregulation-of-Mitochondrial-Translation-Caused
  36. May 2023
  37. www.sciencedirect.com www.sciencedirect.com
    Dissecting the effects of GTPase and kinase domain mutations on LRRK2 endosomal localization and activity
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      DOI: 10.1016/j.celrep.2023.112447

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    sciencedirect.com/science/article/pii/S2211124723004588
  38. Apr 2023
  39. www.sciencedirect.com www.sciencedirect.com
    Integrative genetic analysis identifies FLVCR1 as a plasma-membrane choline transporter in mammals
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    1. scibot 26 Apr 2023
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      DOI: 10.1016/j.cmet.2023.04.003

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    sciencedirect.com/science/article/pii/S1550413123001304
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    Lithium ameliorates Niemann-Pick C1 disease phenotypes by impeding STING/SREBP2 activation
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      RRID:AB_2687579

      DOI: 10.1016/j.isci.2023.106613

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    sciencedirect.com/science/article/pii/S2589004223006909
  41. www.sciencedirect.com www.sciencedirect.com
    ATG5 provides host protection acting as a switch in the atg8ylation cascade between autophagy and secretion
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      DOI: 10.1016/j.devcel.2023.03.014

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    sciencedirect.com/science/article/pii/S1534580723001302
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The meiotic LINC complex component KASH5 is an activating adaptor for cytoplasmic dynein
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      DOI: 10.1083/jcb.202204042

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    ncbi.nlm.nih.gov/pmc/articles/PMC10071310/
  43. Mar 2023
  44. www.ijbs.com www.ijbs.com
    IFNγ blockade in capillary leak site improves tumour chemotherapy by inhibiting lactate-induced endocytosis of vascular endothelial-cadherins
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      DOI: 10.7150/ijbs.78248

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    ijbs.com/v19p1490.htm
  45. link.springer.com link.springer.com
    Disrupted myelin lipid metabolism differentiates frontotemporal dementia caused by GRN and C9orf72 gene mutations
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      DOI: 10.1186/s40478-023-01544-7

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    link.springer.com/article/10.1186/s40478-023-01544-7
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Celastrol directly binds with VAMP7 and RAB7 to inhibit autophagy and induce apoptosis in preadipocytes
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      DOI: 10.3389/fphar.2023.1094584

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    ncbi.nlm.nih.gov/pmc/articles/PMC10027750/
  47. www.sciencedirect.com www.sciencedirect.com
    A central chaperone-like role for 14-3-3 proteins in human cells
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    sciencedirect.com/science/article/pii/S1097276523001211
  48. www.biorxiv.org www.biorxiv.org
    Two RNA-binding proteins mediate the sorting of miR223 from mitochondria into exosomes
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      DOI: 10.1101/2023.01.11.523558

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    biorxiv.org/content/10.1101/2023.01.11.523558v1
  49. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    A glycine-serine-alanine-rich peptide ameliorates Alzheimer-type neurodegeneration
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      DOI: 10.1111/bph.16048

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16048
  50. Feb 2023
  51. www.sciencedirect.com www.sciencedirect.com
    GPR143 controls ESCRT-dependent exosome biogenesis and promotes cancer metastasis
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      DOI: 10.1016/j.devcel.2023.01.006

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    sciencedirect.com/science/article/pii/S1534580723000370
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The SARS-CoV-2 accessory protein Orf3a is not an ion channel, but does interact with trafficking proteins
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      DOI: 10.7554/eLife.84477

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    ncbi.nlm.nih.gov/pmc/articles/PMC9910834/
  53. Dec 2022
  54. www.sciencedirect.com www.sciencedirect.com
    Protocol to purify and detect ubiquitinated phospholipids in budding yeast and human cell lines
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      DOI: 10.1016/j.xpro.2022.101935

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    sciencedirect.com/science/article/pii/S2666166722008152
  55. Sep 2022
  56. www.sciencedirect.com www.sciencedirect.com
    PSMG2-controlled proteasome-autophagy balance mediates the tolerance for MEK-targeted therapy in triple-negative breast cancer
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      DOI: 10.1016/j.xcrm.2022.100741

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    sciencedirect.com/science/article/pii/S2666379122002907
  57. Aug 2022
  58. www.sciencedirect.com www.sciencedirect.com
    Ubiquitination of phosphatidylethanolamine in organellar membranes
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  60. Jul 2022
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    Membrane Targeting and GTPase Activity of Rab7 Are Required for Its Ubiquitination by RNF167
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    Ubiquitin profiling of lysophagy identifies actin stabilizer CNN2 as a target of VCP/p97 and uncovers a link to HSPB1
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  67. May 2022
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    Repurposing Itraconazole and Hydroxychloroquine to Target Lysosomal Homeostasis in Epithelial Ovarian Cancer
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    Protein-lipid interaction at low pH induces oligomerization of the MakA cytotoxin from Vibrio cholerae
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  74. Jan 2022
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    <p>Dynamics of Endocytosis and Degradation of Antibody-Drug Conjugate T-DM1 in HER2 Positive Cancer Cells</p>
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  76. Nov 2021
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    RNF13 Dileucine Motif Variants L311S and L312P Interfere with Endosomal Localization and AP-3 Complex Association
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    Temporal proteomics during neurogenesis reveals large-scale proteome and organelle remodeling via selective autophagy
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    Quantitative proteomics reveals the selectivity of ubiquitin-binding autophagy receptors in the turnover of damaged lysosomes by lysophagy
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    NRF2 promotes urothelial cell response to bacterial infection by regulating reactive oxygen species and RAB27B expression
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  84. Aug 2021
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    Rescue of a lysosomal storage disorder caused by Grn loss of function with a brain penetrant progranulin biologic
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    Targeting Pin1 renders pancreatic cancer eradicable by synergizing with immunochemotherapy
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    A photo-cross-linking GlcNAc analog enables covalent capture of N-linked glycoprotein-binding partners on the cell surface
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  91. Jul 2021
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    Implementation of an antibody characterization procedure and application to the major ALS/FTD disease gene C9ORF72
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    SAC1 regulates autophagosomal phosphatidylinositol-4-phosphate for xenophagy-directed bacterial clearance
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    Tumor-Derived Extracellular Vesicles Breach the Intact Blood–Brain Barrier via Transcytosis
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    MYC competes with MiT/TFE in regulating lysosomal biogenesis and autophagy through an epigenetic rheostat
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    The SARS-CoV-2 Cytopathic Effect Is Blocked by Lysosome Alkalizing Small Molecules
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  99. Jun 2021
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    Systematic Functional Analysis of SARS-CoV-2 Proteins Uncovers Viral Innate Immune Antagonists and Remaining Vulnerabilities
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    ATG4 family proteins drive phagophore growth independently of the LC3/GABARAP lipidation system
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    HIV-infected macrophages resist efficient NK cell-mediated killing while preserving inflammatory cytokine responses
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    Mitochondrial long non-coding RNA GAS5 tunes TCA metabolism in response to nutrient stress
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    Proton-activated chloride channel PAC regulates endosomal acidification and transferrin receptor-mediated endocytosis
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    G3BPs tether the TSC complex to lysosomes and suppress mTORC1 signaling
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    Spatial Multiplexing of Fluorescent Reporters for Imaging Signaling Network Dynamics
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    Targeting the PI5P4K Lipid Kinase Family in Cancer Using Covalent Inhibitors
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    Pharmacological enhancement of TFEB-mediated autophagy alleviated neuronal death in oxidative stress-induced Parkinson’s disease models
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      RRID:AB_2687579

      DOI: 10.1038/s41419-020-2322-6

      Resource: (Cell Signaling Technology Cat# 9091, RRID:AB_2687579)

      Curator: @evieth

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    nature.com/articles/s41419-020-2322-6
  116. www.sciencedirect.com www.sciencedirect.com
    Maintaining Iron Homeostasis Is the Key Role of Lysosomal Acidity for Cell Proliferation
    1
    1. scibot 23 Sep 2020
      RRID:AB_2687579

      DOI: 10.1016/j.molcel.2020.01.003

      Resource: (Cell Signaling Technology Cat# 9091, RRID:AB_2687579)

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    sciencedirect.com/science/article/pii/S1097276520300034
  117. www.sciencedirect.com www.sciencedirect.com
    Targeted Degradation of SLC Transporters Reveals Amenability of Multi-Pass Transmembrane Proteins to Ligand-Induced Proteolysis
    1
    1. scibot 17 Sep 2020
      RRID:AB_2687579

      DOI: 10.1016/j.chembiol.2020.04.003

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    sciencedirect.com/science/article/pii/S2451945620301173
  118. www.sciencedirect.com www.sciencedirect.com
    Immune Sensing of Synthetic, Bacterial, and Protozoan RNA by Toll-like Receptor 8 Requires Coordinated Processing by RNase T2 and RNase 2
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    1. scibot 05 Sep 2020
      RRID:AB_2687579

      DOI: 10.1016/j.immuni.2020.03.009

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    sciencedirect.com/science/article/pii/S1074761320301229
  119. www.sciencedirect.com www.sciencedirect.com
    Shared PPARα/γ Target Genes Regulate Brown Adipocyte Thermogenic Function
    1
    1. scibot 04 Sep 2020
      LAMP1

      DOI: 10.1016/j.celrep.2020.02.032

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    sciencedirect.com/science/article/pii/S2211124720301935
  120. Jan 2020
  121. www.sciencedirect.com www.sciencedirect.com
    Regulation of Autophagic Flux by the 20S Proteasome
    1
    1. scibot 13 Jan 2020
      RRID:AB_2687579

      DOI: 10.1016/j.chembiol.2019.07.002

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    sciencedirect.com/science/article/pii/S2451945619302107
  122. www.sciencedirect.com www.sciencedirect.com
    RAD51AP1 Is an Essential Mediator of Alternative Lengthening of Telomeres
    1
    1. scibot 13 Jan 2020
      RRID:AB_2687579

      DOI: 10.1016/j.molcel.2019.06.043

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    sciencedirect.com/science/article/pii/S1097276519305003
  123. www.jneurosci.org www.jneurosci.org
    Sensory Axon Growth Requires Spatiotemporal Integration of CaSR and TrkB Signaling
    1
    1. scibot 13 Jan 2020
      RRID:AB_2687579

      DOI: 10.1523/JNEUROSCI.0027-19.2019

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    jneurosci.org/content/39/30/5842
  124. www.sciencedirect.com www.sciencedirect.com
    Loss of SATB1 Induces p21-Dependent Cellular Senescence in Post-mitotic Dopaminergic Neurons
    1
    1. scibot 13 Jan 2020
      RRID:AB_2687579

      DOI: 10.1016/j.stem.2019.08.013

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    sciencedirect.com/science/article/pii/S1934590919303480
  125. www.sciencedirect.com www.sciencedirect.com
    LC3C-Mediated Autophagy Selectively Regulates the Met RTK and HGF-Stimulated Migration and Invasion
    1
    1. scibot 13 Jan 2020
      RRID:AB_2687579

      DOI: 10.1016/j.celrep.2019.11.063

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    sciencedirect.com/science/article/pii/S2211124719315542
  126. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 13 Jan 2020
      RRID:AB_2687579

      DOI: 10.1016/j.molcel.2018.12.017

      Resource: (Cell Signaling Technology Cat# 9091, RRID:AB_2687579)

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    sciencedirect.com/science/article/pii/S1097276518310712
  127. www.sciencedirect.com www.sciencedirect.com
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    1. scibot 13 Jan 2020
      RRID:AB_2687579

      DOI: 10.1016/j.devcel.2019.04.014

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    sciencedirect.com/science/article/pii/S1534580719302849
  128. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 12 Jan 2020
      RRID:AB_2687579

      DOI: 10.1016/j.devcel.2019.03.011

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    sciencedirect.com/science/article/pii/S1534580719301881
  129. Nov 2018
  130. www.sciencedirect.com www.sciencedirect.com
    iPSCs from a Hibernator Provide a Platform for Studying Cold Adaptation and Its Potential Medical Applications
    1
    1. scibot 05 Nov 2018
      9091

      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S0092867418302903
  131. www.sciencedirect.com www.sciencedirect.com
    Mutations in Disordered Regions Can Cause Disease by Creating Dileucine Motifs
    1
    1. scibot 05 Nov 2018
      RRID:AB_2687579

      Curator: @Jmenke

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      (Cell Signaling Technology Cat# 9091, RRID:AB_2687579)

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    sciencedirect.com/science/article/pii/S0092867418310353
  132. www.sciencedirect.com www.sciencedirect.com
    Leucine Signals to mTORC1 via Its Metabolite Acetyl-Coenzyme A
    1
    1. scibot 05 Nov 2018
      RRID:AB_2687579

      Curator: @evieth

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    sciencedirect.com/science/article/pii/S155041311830514X
  133. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Shutdown of ER-associated degradation pathway rescues functions of mutant iduronate 2-sulfatase linked to mucopolysaccharidosis type II
    1
    1. scibot 05 Nov 2018
      RRID:AB_2687579

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    ncbi.nlm.nih.gov/pmc/articles/PMC6057917/
  134. www.nature.com www.nature.com
    Untitled document
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    1. scibot 05 Nov 2018
      RRID:AB_2687579

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    nature.com/articles/s41419-018-0871-8
  135. www.sciencedirect.com www.sciencedirect.com
    Acid Suspends the Circadian Clock in Hypoxia through Inhibition of mTOR
    1
    1. scibot 05 Nov 2018
      RRID:AB_2687579

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      (Cell Signaling Technology Cat# 9091, RRID:AB_2687579)

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    sciencedirect.com/science/article/pii/S0092867418305865
  136. Nov 2017
  137. www.sciencedirect.com www.sciencedirect.com
    Identification of GPC2 as an Oncoprotein and Candidate Immunotherapeutic Target in High-Risk Neuroblastoma
    1
    1. scibot 09 Nov 2017
      9091S

      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S153561081730346X
  138. www.sciencedirect.com www.sciencedirect.com
    Pacer Mediates the Function of Class III PI3K and HOPS Complexes in Autophagosome Maturation by Engaging Stx17
    1
    1. scibot 08 Nov 2017
      Rabbit polyclonal anti-Lamp1Cell Signaling TechnologyCat#:D2D11

      Curator: @Jmenke

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      (Cell Signaling Technology Cat# 9091, RRID:AB_2687579)

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    sciencedirect.com/science/article/pii/S1097276517301247
  139. www.sciencedirect.com www.sciencedirect.com
    Bromodomain Protein BRD4 Is a Transcriptional Repressor of Autophagy and Lysosomal Function
    1
    1. scibot 08 Nov 2017
      Rabbit monoclonal anti-LAMP1 (clone D2D11)Cell Signaling TechnologyCat#: 9091P

      Curator: @Jmenke

      Resource used:

      (Cell Signaling Technology Cat# 9091, RRID:AB_2687579)

      SciCrunch record: RRID:AB_2687579

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      RRID:AB_2687579 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S109727651730312X