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Accumulation of succinate suppresses de novo purine synthesis through succinylation-mediated control of the mitochondrial folate cycle

1
1. scibot 29 Oct 2025
  
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  RRID:AB_2687628
  
  DOI: 10.1016/j.molcel.2025.10.002
  
  Resource: (PTM BIO Cat# PTM-401, RRID:AB_2687628)
  
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sciencedirect.com/science/article/pii/S1097276525008196
Aug 2025
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SUCLG1 deficiency-induced histone succinylation impairs oncogene expression in acute myeloid leukemia

1
1. scibot 13 Aug 2025
  
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  RRID:AB_2687628
  
  DOI: 10.1016/j.celrep.2025.116147
  
  Resource: (PTM BIO Cat# PTM-401, RRID:AB_2687628)
  
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sciencedirect.com/science/article/pii/S2211124725009180
Feb 2025
www.science.org www.science.org

Succinylation enables IDE to act as a hub of larval tissue destruction and adult tissue reconstruction during insect metamorphosis

1
1. scibot 07 Feb 2025
  
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  RRID:AB_2687628
  
  DOI: 10.1126/sciadv.ads0643
  
  Resource: (PTM BIO Cat# PTM-401, RRID:AB_2687628)
  
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science.org/doi/10.1126/sciadv.ads0643
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Succinylation enables IDE to act as a hub of larval tissue destruction and adult tissue reconstruction during insect metamorphosis

1
1. scibot 07 Feb 2025
  
  in Public
  
  RRID:AB_2687628
  
  DOI: 10.1126/sciadv.ads0643
  
  Resource: (PTM BIO Cat# PTM-401, RRID:AB_2687628)
  
  Curator: @scibot
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11797550/
Jan 2025
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OXCT1 succinylation and activation by SUCLA2 promotes ketolysis and liver tumor growth

1
1. scibot 28 Jan 2025
  
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  RRID:AB_2687628
  
  DOI: 10.1016/j.molcel.2024.12.025
  
  Resource: (PTM BIO Cat# PTM-401, RRID:AB_2687628)
  
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sciencedirect.com/science/article/pii/S1097276524010669
Aug 2024
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Glycometabolic reprogramming-induced XRCC1 lactylation confers therapeutic resistance in ALDH1A3-overexpressing glioblastoma

1
1. scibot 19 Aug 2024
  
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  AB_2937058
  
  DOI: 10.1016/j.cmet.2024.07.011
  
  Resource: (PTM BIO Cat# PTM-401, RRID:AB_2687628)
  
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sciencedirect.com/science/article/pii/S1550413124002821
Jul 2024
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Astrocytic LRP1 enables mitochondria transfer to neurons and mitigates brain ischemic stroke by suppressing ARF1 lactylation

1
1. scibot 24 Jul 2024
  
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  AB_2687628
  
  DOI: 10.1016/j.cmet.2024.05.016
  
  Resource: (PTM BIO Cat# PTM-401, RRID:AB_2687628)
  
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sciencedirect.com/science/article/pii/S155041312400192X
Jun 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Human SIRT5 variants with reduced stability and activity do not cause neuropathology in mice

1
1. scibot 09 Jun 2024
  
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  RRID:AB_2687628
  
  DOI: 10.1016/j.isci.2024.109991
  
  Resource: (PTM BIO Cat# PTM-401, RRID:AB_2687628)
  
  Curator: @scibot
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11154205/
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Mitochondrial glycerol 3-phosphate dehydrogenase deficiency exacerbates lipotoxic cardiomyopathy

1
1. scibot 07 Jun 2024
  
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  RRID:AB_2687628
  
  DOI: 10.1016/j.isci.2024.109796
  
  Resource: (PTM BIO Cat# PTM-401, RRID:AB_2687628)
  
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sciencedirect.com/science/article/pii/S2589004224010186
Jun 2023
www.science.org www.science.org

Succinate metabolism and membrane reorganization drives the endotheliopathy and coagulopathy of traumatic hemorrhage

1
1. scibot 22 Jun 2023
  
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  RRID:AB_2687628
  
  DOI: 10.1126/sciadv.adf6600
  
  Resource: (PTM BIO Cat# PTM-401, RRID:AB_2687628)
  
  Curator: @scibot
  
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science.org/doi/10.1126/sciadv.adf6600
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Succinate metabolism and membrane reorganization drives the endotheliopathy and coagulopathy of traumatic hemorrhage

1
1. scibot 17 Jun 2023
  
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  RRID:AB_2687628
  
  DOI: 10.1126/sciadv.adf6600
  
  Resource: (PTM BIO Cat# PTM-401, RRID:AB_2687628)
  
  Curator: @scibot
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10266735/
Apr 2023
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Malonylation of Acetyl-CoA carboxylase 1 promotes hepatic steatosis and is attenuated by ketogenic diet in NAFLD

1
1. scibot 04 Apr 2023
  
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  RRID:AB_2687628
  
  DOI: 10.1016/j.celrep.2023.112319
  
  Resource: (PTM BIO Cat# PTM-401, RRID:AB_2687628)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S2211124723003303
Jan 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Ischemic accumulation of succinate induces Cdc42 succinylation and inhibits neural stem cell proliferation after cerebral ischemia/reperfusion

1
1. scibot 11 Jan 2023
  
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  RRID:AB_2687628
  
  DOI: 10.4103/1673-5374.355821
  
  Resource: (PTM BIO Cat# PTM-401, RRID:AB_2687628)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2687628
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9827777/
Dec 2021
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NEAT1 is essential for metabolic changes that promote breast cancer growth and metastasis

1
1. scibot 08 Dec 2021
  
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  RRID:AB_2687628
  
  DOI: 10.1016/j.cmet.2021.11.011
  
  Resource: (PTM BIO Cat# PTM-401, RRID:AB_2687628)
  
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sciencedirect.com/science/article/pii/S1550413121005398
Aug 2021
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Regulation of UCP1 and Mitochondrial Metabolism in Brown Adipose Tissue by Reversible Succinylation

1
1. scibot 03 Aug 2021
  
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  RRID:AB_2687628
  
  DOI: 10.1016/j.molcel.2019.03.021
  
  Resource: (PTM BIO Cat# PTM-401, RRID:AB_2687628)
  
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sciencedirect.com/science/article/pii/S1097276519302254
Sep 2020
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Pimozide Alleviates Hyperglycemia in Diet-Induced Obesity by Inhibiting Skeletal Muscle Ketone Oxidation

1
1. scibot 05 Sep 2020
  
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  RRID:AB_2687628
  
  DOI: 10.1016/j.cmet.2020.03.017
  
  Resource: (PTM Biolabs Cat# PTM-401, RRID:AB_2687628)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2687628
  
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  RRIDCUR:Validated RRID:AB_2687628
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RRIDCUR:Validated

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sciencedirect.com/science/article/pii/S1550413120301327
Nov 2018
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Protein Acylation is a General Regulatory Mechanism in Biosynthetic Pathway of Acyl-CoA-Derived Natural Products

1
1. scibot 05 Nov 2018
  
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  RRID:AB_2687628
  
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  (PTM Biolabs Cat# PTM-401, RRID:AB_2687628)
  
  SciCrunch record: RRID:AB_2687628
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
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sciencedirect.com/science/article/pii/S2451945618301521
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Site-Specific Installation of Succinyl Lysine Analog into Histones Reveals the Effect of H2BK34 Succinylation on Nucleosome Dynamics

1
1. scibot 05 Nov 2018
  
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  RRID:AB_2687628
  
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  (PTM Biolabs Cat# PTM-401, RRID:AB_2687628)
  
  SciCrunch record: RRID:AB_2687628
  
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  RRID:AB_2687628
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sciencedirect.com/science/article/pii/S2451945617304221
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A Potent and Specific CD38 Inhibitor Ameliorates Age-Related Metabolic Dysfunction by Reversing Tissue NAD+ Decline

1
1. scibot 05 Nov 2018
  
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  RRID:AB_2687628
  
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  (PTM Biolabs Cat# PTM-401, RRID:AB_2687628)
  
  SciCrunch record: RRID:AB_2687628
  
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sciencedirect.com/science/article/pii/S1550413118301943
Nov 2017
www.sciencedirect.com www.sciencedirect.com

Sirtuin 5 protects mitochondria from fragmentation and degradation during starvation

1
1. scibot 08 Nov 2017
  
  in Public
  
  PTM-401
  
  Curator: @Jmenke
  
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  (PTM Biolabs Cat# PTM-401, RRID:AB_2687628)
  
  SciCrunch record: RRID:AB_2687628
  
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  RRID:AB_2687628 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S0167488916302774
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The Mammalian Malonyl-CoA Synthetase ACSF3 Is Required for Mitochondrial Protein Malonylation and Metabolic Efficiency

1
1. scibot 08 Nov 2017
  
  in Public
  
  α-succinyl-lysine, rabbit polyclonalPTM BiolabsCat#401
  
  Curator: @Jmenke
  
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  (PTM Biolabs Cat# PTM-401, RRID:AB_2687628)
  
  SciCrunch record: RRID:AB_2687628
  
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  RRID:AB_2687628 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S2451945617301095