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Olaparib and radiotherapy induce type I interferon and CD8+ T cell-dependent sensitization to immunotherapy in pancreatic cancer

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1. scibot 05 Dec 2025
  
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  DOI: 10.1158/1535-7163.MCT-24-0210
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12137021/
Nov 2025
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Virus envelope glycoprotein targeting bispecific T cell engager protects mice from lethal severe fever with thrombocytopenia virus infection

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1. scibot 22 Nov 2025
  
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  DOI: 10.1016/j.xcrm.2025.102458
  
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sciencedirect.com/science/article/pii/S2666379125005312
Oct 2025
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Super-adjuvant nanoparticles for platform cancer vaccination

1
1. scibot 15 Oct 2025
  
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  DOI: 10.1016/j.xcrm.2025.102415
  
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sciencedirect.com/science/article/pii/S2666379125004884
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In situ extended immune activation instantly after tumor resection by oncolytic virus controls postoperative tumor recurrence

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1. scibot 08 Oct 2025
  
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  DOI: 10.1016/j.xcrm.2025.102399
  
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sciencedirect.com/science/article/pii/S2666379125004720
Sep 2025
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ZBP1 pathway promotes tumor immunogenicity in the combination of anti-HER2 therapy and epigenetic therapy

1
1. scibot 17 Sep 2025
  
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  DOI: 10.1016/j.celrep.2025.116314
  
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sciencedirect.com/science/article/pii/S221112472501085X
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Innate immune sensing of Z-nucleic acids by ZBP1-RIPK1 axis drives neuroinflammation in Alzheimer’s disease

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1. scibot 03 Sep 2025
  
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  DOI: 10.1016/j.immuni.2025.07.024
  
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sciencedirect.com/science/article/pii/S1074761325003334
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Cancer cell and microenvironmental rewiring by ADAR1 loss impairs glioblastoma tumor growth and extends survival

1
1. scibot 03 Sep 2025
  
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  DOI: 10.1016/j.celrep.2025.116151
  
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sciencedirect.com/science/article/pii/S2211124725009222
Aug 2025
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Macrophages orchestrate elimination of Shigella from the intestinal epithelial cell niche via TLR-induced IL-12 and IFN-γ

1
1. scibot 30 Aug 2025
  
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  RRID:AB_2687723
  
  DOI: 10.1016/j.chom.2025.08.001
  
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sciencedirect.com/science/article/pii/S1931312825002975
Jul 2025
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Targeting Intracellular Innate RNA-Sensing Systems Overcomes Resistance to CAR T-cell Therapy in Solid Tumors

1
1. scibot 17 Jul 2025
  
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  RRID:AB_2687723
  
  DOI: 10.1158/0008-5472.CAN-24-3425
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12260516/
Jun 2025
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Interferon-epsilon, an estrogen-induced type I interferon, is uniquely exploited by Neisseria gonorrhoeae via effects on sialic acid metabolism

1
1. scibot 11 Jun 2025
  
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  RRID:AB_2687723
  
  DOI: 10.1016/j.chom.2025.05.015
  
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sciencedirect.com/science/article/pii/S1931312825001982
Feb 2025
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Nanoparticle delivery of innate immune agonists combined with senescence-inducing agents promotes T cell control of pancreatic cancer

1
1. scibot 13 Feb 2025
  
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  RRID:AB_2687723
  
  DOI: 10.1126/scitranslmed.adj9366
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11811823/
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Mechanistic insight into the induction of liver tissue-resident memory CD8+ T cells by glycolipid-peptide vaccination

1
1. scibot 13 Feb 2025
  
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  AB_2687723
  
  DOI: 10.1016/j.celrep.2025.115295
  
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sciencedirect.com/science/article/pii/S221112472500066X
Nov 2024
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Type III interferons induce pyroptosis in gut epithelial cells and impair mucosal repair

1
1. scibot 16 Nov 2024
  
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  RRID:AB_2687723
  
  DOI: 10.1016/j.cell.2024.10.010
  
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sciencedirect.com/science/article/pii/S0092867424011589
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Targeting Catechol-O-Methyltransferase Induces Mitochondrial Dysfunction and Enhances the Efficacy of Radiotherapy in Glioma

1
1. scibot 08 Nov 2024
  
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  RRID:AB_2687723
  
  DOI: 10.1158/0008-5472.CAN-24-0134
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11532787/
Jul 2024
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VHL loss enhances antitumor immunity by activating the anti-viral DNA-sensing pathway

1
1. scibot 27 Jul 2024
  
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  RRID:AB_2687723
  
  DOI: 10.1016/j.isci.2024.110285
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11267025/
Jun 2024
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Opposing tumor-cell-intrinsic and -extrinsic roles of the IRF1 transcription factor in antitumor immunity

1
1. scibot 04 Jun 2024
  
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  RRID:AB_2687723
  
  DOI: 10.1016/j.celrep.2024.114289
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11315447/
Apr 2024
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Squalene-epoxidase-catalyzed 24(S),25-epoxycholesterol synthesis promotes trained-immunity-mediated antitumor activity

2
1. scibot 18 Apr 2024
  
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  RRID:AB_2687723
  
  DOI: 10.1016/j.celrep.2024.114094
  
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2. scibot 18 Apr 2024
  
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  RRID:AB_2687723
  
  DOI: 10.1016/j.celrep.2024.114094
  
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sciencedirect.com/science/article/pii/S2211124724004224
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Type I interferons induce an epigenetically distinct memory B cell subset in chronic viral infection

1
1. scibot 09 Apr 2024
  
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  RRID:AB_2687723
  
  DOI: 10.1016/j.immuni.2024.03.016
  
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sciencedirect.com/science/article/pii/S1074761324001377
Jan 2024
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Interferon-stimulated neutrophils as a predictor of immunotherapy response

1
1. scibot 09 Jan 2024
  
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  RRID:AB_2687723
  
  DOI: 10.1016/j.ccell.2023.12.005
  
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sciencedirect.com/science/article/pii/S1535610823004336
Dec 2023
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Reprogramming of tumor-associated macrophages via NEDD4-mediated CSF1R degradation by targeting USP18

1
1. scibot 17 Dec 2023
  
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  RRID:AB_2687723
  
  DOI: 10.1016/j.celrep.2023.113560
  
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sciencedirect.com/science/article/pii/S2211124723015723
Oct 2023
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Serotonin reduction in post-acute sequelae of viral infection

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1. scibot 28 Oct 2023
  
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  RRID:AB_2687723
  
  DOI: 10.1016/j.cell.2023.09.013
  
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sciencedirect.com/science/article/pii/S0092867423010346
Sep 2023
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STING signaling promotes NK cell antitumor immunity and maintains a reservoir of TCF-1+ NK cells

2
1. scibot 16 Sep 2023
  
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  RRID:AB_2687723
  
  DOI: 10.1016/j.celrep.2023.113108
  
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2. scibot 16 Sep 2023
  
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  RRID:AB_2687723
  
  DOI: 10.1016/j.celrep.2023.113108
  
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sciencedirect.com/science/article/pii/S2211124723011191
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Targeting nucleic acid sensors in tumor cells to reprogram biogenesis and RNA cargo of extracellular vesicles for T cell-mediated cancer immunotherapy

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1. scibot 01 Sep 2023
  
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  RRID:AB_2687723
  
  DOI: 10.1016/j.xcrm.2023.101171
  
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sciencedirect.com/science/article/pii/S2666379123003245
Aug 2023
52.53.155.43 52.53.155.43

Targeting TCF19 sensitizes MSI endometrial cancer to anti-PD-1 therapy by alleviating CD8+ T cell exhaustion via TRIM14-IFN-β axis

2
1. scibot 17 Aug 2023
  
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  RRID:AB_2687723
  
  DOI: 10.1016/j.celrep.2023.112944
  
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2. scibot 11 Aug 2023
  
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  DOI: 10.1016/j.celrep.2023.112944
  
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52.53.155.43/f1aa479ee50c1426738d478d555cd8c52a91c49e/PIIS2211124723009555-html.html
Jun 2023
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Cooperative sensing of mitochondrial DNA by ZBP1 and cGAS promotes cardiotoxicity

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1. scibot 23 Jun 2023
  
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  RRID:AB_2687723
  
  DOI: 10.1016/j.cell.2023.05.039
  
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sciencedirect.com/science/article/pii/S0092867423005913
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Intravenous heterologous prime-boost vaccination activates innate and adaptive immunity to promote tumor regression

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1. scibot 08 Jun 2023
  
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  RRID:AB_2687723
  
  DOI: 10.1016/j.celrep.2023.112599
  
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sciencedirect.com/science/article/pii/S2211124723006101
Mar 2023
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IFNγ is a central node of cancer immune equilibrium

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1. scibot 09 Mar 2023
  
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  RRID:AB_2687723
  
  DOI: 10.1016/j.celrep.2023.112219
  
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sciencedirect.com/science/article/pii/S2211124723002309
Feb 2023
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Zika virus spreads through infection of lymph node-resident macrophages

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1. scibot 16 Feb 2023
  
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  RRID:AB_2687723
  
  DOI: 10.1016/j.celrep.2023.112126
  
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sciencedirect.com/science/article/pii/S2211124723001377
Jan 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

SETDB1 Restrains Endogenous Retrovirus Expression and Antitumor Immunity during Radiotherapy

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1. scibot 12 Jan 2023
  
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  DOI: 10.1158/0008-5472.CAN-21-3523
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9357127/
Dec 2022
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Cancer cell-derived type I interferons instruct tumor monocyte polarization

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1. scibot 08 Dec 2022
  
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  DOI: 10.1016/j.celrep.2022.111769
  
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sciencedirect.com/science/article/pii/S2211124722016527
Nov 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

GPI-Anchored Ligand-BioID2-Tagging System Identifies Galectin-1 Mediating Zika Virus Entry

1
1. scibot 19 Nov 2022
  
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  RRID:AB_2687723
  
  DOI: 10.1016/j.isci.2022.105481
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9668739/
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Driving axon regeneration by orchestrating neuronal and non-neuronal innate immune responses via the IFNγ-cGAS-STING axis

1
1. scibot 16 Nov 2022
  
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  RRID:AB_2687723
  
  DOI: 10.1016/j.neuron.2022.10.028
  
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sciencedirect.com/science/article/pii/S0896627322009618
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The transcription factor IRF2 drives interferon-mediated CD8+ T cell exhaustion to restrict anti-tumor immunity

1
1. scibot 15 Nov 2022
  
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  RRID:AB_2687723
  
  DOI: 10.1016/j.immuni.2022.10.020
  
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sciencedirect.com/science/article/pii/S1074761322005611
Oct 2022
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Systemic vaccination induces CD8+ T cells and remodels the tumor microenvironment

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Concerted type I interferon signaling in microglia and neural cells promotes memory impairment associated with amyloid β plaques

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AXL targeting restores PD-1 blockade sensitivity of STK11/LKB1 mutant NSCLC through expansion of TCF1+ CD8 T cells

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Interferon-β acts directly on T cells to prolong allograft survival by enhancing regulatory T cell induction through Foxp3 acetylation

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MEK inhibition overcomes chemoimmunotherapy resistance by inducing CXCL10 in cancer cells

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ADAR1 restricts ZBP1-mediated immune response and PANoptosis to promote tumorigenesis

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In vivo characterization of emerging SARS-CoV-2 variant infectivity and human antibody escape potential

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Microbiota triggers STING-type I IFN-dependent monocyte reprogramming of the tumor microenvironment

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Untitled document

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Cell-autonomous inflammation of BRCA1-deficient ovarian cancers drives both tumor-intrinsic immunoreactivity and immune resistance via STING

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PARP7 negatively regulates the type I interferon response in cancer cells and its inhibition triggers antitumor immunity

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Interferon-α-producing plasmacytoid dendritic cells drive the loss of adipose tissue regulatory T cells during obesity

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Endogenous retroviruses promote homeostatic and inflammatory responses to the microbiota

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The inhibitory receptor TIM-3 limits activation of the cGAS-STING pathway in intra-tumoral dendritic cells by suppressing extracellular DNA uptake

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Early innate and adaptive immune perturbations determine long-term severity of chronic virus and Mycobacterium tuberculosis coinfection

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DNA Sensing in Mismatch Repair-Deficient Tumor Cells Is Essential for Anti-tumor Immunity

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IL-21/type I interferon interplay regulates neutrophil-dependent innate immune responses to Staphylococcus aureus

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Systemic Inflammation Suppresses Lymphoid Tissue Remodeling and B Cell Immunity during Concomitant Local Infection

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The Unfolded Protein Response Mediator PERK Governs Myeloid Cell-Driven Immunosuppression in Tumors through Inhibition of STING Signaling

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Type I interferon underlies severe disease associated with Junín virus infection in mice

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Blockade of the Phagocytic Receptor MerTK on Tumor-Associated Macrophages Enhances P2X7R-Dependent STING Activation by Tumor-Derived cGAMP

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Gasdermin D Restrains Type I Interferon Response to Cytosolic DNA by Disrupting Ionic Homeostasis

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Non-canonical NF-κB Antagonizes STING Sensor-Mediated DNA Sensing in Radiotherapy

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Self-Renewal and Toll-like Receptor Signaling Sustain Exhausted Plasmacytoid Dendritic Cells during Chronic Viral Infection

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TIM-3 Regulates CD103+ Dendritic Cell Function and Response to Chemotherapy in Breast Cancer

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Dichotomous Expression of TNF Superfamily Ligands on Antigen-Presenting Cells Controls Post-priming Anti-viral CD4+ T Cell Immunity

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