59 Matching Annotations
  1. Last 7 days
  2. www.biorxiv.org www.biorxiv.org
    Immune Checkpoint Inhibition-related Neuroinflammation Disrupts Cognitive Function
    1
    1. scibot 16 Jul 2024
      RRID:AB_2687796

      DOI: 10.1101/2024.07.01.601087

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    biorxiv.org/content/10.1101/2024.07.01.601087v1
  3. May 2024
  4. www.sciencedirect.com www.sciencedirect.com
    A computational pipeline for identifying gene targets and signalling pathways in cancer cells to improve lymphocyte infiltration and immune checkpoint therapy efficacy
    1
    1. scibot 30 May 2024
      RRID:AB_2687796

      DOI: 10.1016/j.ebiom.2024.105167

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    sciencedirect.com/science/article/pii/S2352396424002020
  5. www.sciencedirect.com www.sciencedirect.com
    Metabolic regulator LKB1 controls adipose tissue ILC2 PD-1 expression and mitochondrial homeostasis to prevent insulin resistance
    1
    1. scibot 21 May 2024
      RRID:AB_2687796

      DOI: 10.1016/j.immuni.2024.04.024

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    sciencedirect.com/science/article/pii/S1074761324002292
  6. www.sciencedirect.com www.sciencedirect.com
    Circadian tumor infiltration and function of CD8+ T cells dictate immunotherapy efficacy
    1
    1. scibot 09 May 2024
      AB_2687796

      DOI: 10.1016/j.cell.2024.04.015

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    sciencedirect.com/science/article/pii/S0092867424004100
  7. Apr 2024
  8. www.sciencedirect.com www.sciencedirect.com
    Exogenous non-coding dsDNA-dependent trans-activation of phagocytes augments anti-tumor immunity
    1
    1. scibot 30 Apr 2024
      BioXcellBP0273

      DOI: 10.1016/j.xcrm.2024.101528

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    sciencedirect.com/science/article/pii/S2666379124001976
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The diversity of inhibitory receptor co-expression patterns of exhausted CD8+ T cells in oropharyngeal carcinoma
    1
    1. scibot 28 Apr 2024
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      DOI: 10.1016/j.isci.2024.109668

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    ncbi.nlm.nih.gov/pmc/articles/PMC11035373/
  10. www.sciencedirect.com www.sciencedirect.com
    IGSF8 is an innate immune checkpoint and cancer immunotherapy target
    1
    1. scibot 24 Apr 2024
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      DOI: 10.1016/j.cell.2024.03.039

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    sciencedirect.com/science/article/pii/S0092867424003556
  11. www.nature.com www.nature.com
    Targeting branched N-glycans and fucosylation sensitizes ovarian tumors to immune checkpoint blockade
    1
    1. scibot 03 Apr 2024
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      DOI: 10.1038/s41467-024-47069-y

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    nature.com/articles/s41467-024-47069-y
  12. Mar 2024
  13. www.thno.org www.thno.org
    Vitamin D binding protein (VDBP) hijacks twist1 to inhibit vasculogenic mimicry in hepatocellular carcinoma
    1
    1. scibot 30 Mar 2024
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      DOI: 10.7150/thno.90322

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    thno.org/v14p0436.htm
  14. www-cell-com.proxy.uchicago.edu www-cell-com.proxy.uchicago.edu
    Microbial metabolite enhances immunotherapy efficacy by modulating T cell stemness in pan-cancer
    1
    1. scibot 15 Mar 2024
      RRID:AB_2687796

      DOI: 10.1016/j.cell.2024.02.022

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    www-cell-com.proxy.uchicago.edu/cell/fulltext/S0092-8674(24)00224-1
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    S100A9+CD14+ monocytes contribute to anti-PD-1 immunotherapy resistance in advanced hepatocellular carcinoma by attenuating T cell-mediated antitumor function
    1
    1. scibot 12 Mar 2024
      RRID:AB_2687796

      DOI: 10.1186/s13046-024-02985-1

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    ncbi.nlm.nih.gov/pmc/articles/PMC10921725/
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bcl-xL targeting eliminates ageing tumor-promoting neutrophils and inhibits lung tumor growth
    1
    1. scibot 03 Mar 2024
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      DOI: 10.1038/s44321-023-00013-x

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    ncbi.nlm.nih.gov/pmc/articles/PMC10897164/
  17. Feb 2024
  18. www.sciencedirect.com www.sciencedirect.com
    UFL1 ablation in T cells suppresses PD-1 UFMylation to enhance anti-tumor immunity
    1
    1. scibot 28 Feb 2024
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      DOI: 10.1016/j.molcel.2024.01.024

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    sciencedirect.com/science/article/pii/S1097276524000911
  19. aacrjournals.org aacrjournals.org
    RNA methyltransferase FTSJ3 regulates the type I interferon pathway to promote hepatocellular carcinoma immune evasion
    2
    1. scibot 23 Feb 2024
      RRID:AB_2687796

      DOI: 10.1158/0008-5472.CAN-23-2049

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    2. scibot 23 Feb 2024
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      DOI: 10.1158/0008-5472.CAN-23-2049

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    aacrjournals.org/cancerres/article/84/3/405/733849/RNA-Methyltransferase-FTSJ3-Regulates-the-Type-I
  20. Jan 2024
  21. dx.doi.org dx.doi.org
    Formate supplementation enhances anti-tumor CD8+ T cell fitness and efficacy of PD-1 blockade
    1
    1. scibot 11 Jan 2024
      RRID:AB_2687796

      DOI: 10.1158/2159-8290.CD-22-1301

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    dx.doi.org/10.1158/2159-8290.CD-22-1301
  22. 52.53.155.43 52.53.155.43
    Mitochondria-ER contact mediated by MFN2-SERCA2 interaction supports CD8+ T cell metabolic fitness and function in tumors
    1
    1. scibot 10 Jan 2024
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      DOI: 10.1126/sciimmunol.abq2424

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    52.53.155.43/93ebbe5a83b6a28b0d01edad42fa81f437079176/sciimmunol.abq2424_sm-html.html
  23. Dec 2023
  24. www.embopress.org www.embopress.org
    Bcl-xL targeting eliminates ageing tumor-promoting neutrophils and inhibits lung tumor growth
    1
    1. scibot 29 Dec 2023
      RRID:AB_2687796

      DOI: 10.1038/s44321-023-00013-x

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    embopress.org/doi/10.1038/s44321-023-00013-x
  25. 52.53.155.43 52.53.155.43
    cd-22-1301-html.html
    1
    1. scibot 01 Dec 2023
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      DOI: 10.1158/2159-8290.cd-22-1301

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    52.53.155.43/ed2c7eab61775ee4a9efbdfa91d6b4b18a13354a/cd-22-1301-html.html
  26. Oct 2023
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The CX3CL1-CX3CR1 chemokine axis can contribute to tumor immune evasion and blockade with a novel CX3CR1 monoclonal antibody enhances response to anti-PD-1 immunotherapy
    1
    1. scibot 06 Oct 2023
      AB_2687796

      DOI: 10.3389/fimmu.2023.1237715

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    ncbi.nlm.nih.gov/pmc/articles/PMC10524267/
  28. Sep 2023
  29. www.sciencedirect.com www.sciencedirect.com
    Ablation of ERO1A induces lethal endoplasmic reticulum stress responses and immunogenic cell death to activate anti-tumor immunity
    1
    1. scibot 30 Sep 2023
      RRID:AB_2687796

      DOI: 10.1016/j.xcrm.2023.101206

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    sciencedirect.com/science/article/pii/S2666379123003737
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sex-Biased T-cell Exhaustion Drives Differential Immune Responses in Glioblastoma
    1
    1. scibot 09 Sep 2023
      RRID:AB_2687796

      DOI: 10.1158/2159-8290.CD-22-0869

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    ncbi.nlm.nih.gov/pmc/articles/PMC10481130/
  31. Aug 2023
  32. www.sciencedirect.com www.sciencedirect.com
    KRASG12D inhibition reprograms the microenvironment of early and advanced pancreatic cancer to promote FAS-mediated killing by CD8+ T cells
    1
    1. scibot 25 Aug 2023
      RRID:AB_2687796

      DOI: 10.1016/j.ccell.2023.07.002

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    sciencedirect.com/science/article/abs/pii/S1535610823002428
  33. 52.53.155.43 52.53.155.43
    CD39 inhibition and VISTA blockade may overcome radiotherapy resistance by targeting exhausted CD8+ T cells and immunosuppressive myeloid cells
    2
    1. scibot 17 Aug 2023
      RRID:AB_2687796

      DOI: 10.1016/j.xcrm.2023.101151

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      DOI: 10.1016/j.xcrm.2023.101151

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    52.53.155.43/75914c2645b295883453ae6f0848b8ff04ccb7e0/PIIS266637912300304X-html.html
  34. www.sciencedirect.com www.sciencedirect.com
    Selective targeting of IL2Rβγ combined with radiotherapy triggers CD8- and NK-mediated immunity, abrogating metastasis in HNSCC
    1
    1. scibot 16 Aug 2023
      RRID:AB_2687796

      DOI: 10.1016/j.xcrm.2023.101150

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    sciencedirect.com/science/article/pii/S2666379123003038
  35. 52.53.155.43 52.53.155.43
    Membrane-localized neoantigens predict the efficacy of cancer immunotherapy
    2
    1. scibot 12 Aug 2023
      RRID:AB_2687796

      DOI: 10.1016/j.xcrm.2023.101145

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    2. scibot 10 Aug 2023
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      DOI: 10.1016/j.xcrm.2023.101145

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    52.53.155.43/9f1a09025b86686c62561e67323b0c82e4153e7b/PIIS2666379123002987-html.html
  36. Jul 2023
  37. www.sciencedirect.com www.sciencedirect.com
    Tumor aerobic glycolysis confers immune evasion through modulating sensitivity to T cell-mediated bystander killing via TNF-α
    1
    1. scibot 28 Jul 2023
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      DOI: 10.1016/j.cmet.2023.07.001

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    sciencedirect.com/science/article/abs/pii/S1550413123002516
  38. www.sciencedirect.com www.sciencedirect.com
    Cancer-associated mesothelial cells are regulated by the anti-Müllerian hormone axis
    1
    1. scibot 15 Jul 2023
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      DOI: 10.1016/j.celrep.2023.112730

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    sciencedirect.com/science/article/pii/S2211124723007416
  39. Apr 2023
  40. www.sciencedirect.com www.sciencedirect.com
    Lymphocyte networks are dynamic cellular communities in the immunoregulatory landscape of lung adenocarcinoma
    1
    1. scibot 14 Apr 2023
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      DOI: 10.1016/j.ccell.2023.03.015

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    sciencedirect.com/science/article/pii/S1535610823000880
  41. www.sciencedirect.com www.sciencedirect.com
    Synergistic effects of combined immunotherapy strategies in a model of multifocal hepatocellular carcinoma
    1
    1. scibot 12 Apr 2023
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      DOI: 10.1016/j.xcrm.2023.101009

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    sciencedirect.com/science/article/pii/S2666379123001192
  42. www.nature.com www.nature.com
    Targeting USP2 regulation of VPRBP-mediated degradation of p53 and PD-L1 for cancer therapy
    1
    1. scibot 11 Apr 2023
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      DOI: 10.1038/s41467-023-37617-3

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    nature.com/articles/s41467-023-37617-3
  43. Feb 2023
  44. www.sciencedirect.com www.sciencedirect.com
    IDH2 and TET2 mutations synergize to modulate T Follicular Helper cell functional interactionwith the AITL microenvironment
    1
    1. scibot 03 Feb 2023
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      DOI: 10.1016/j.ccell.2023.01.003

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    sciencedirect.com/science/article/pii/S153561082300003X
  45. Jul 2022
  46. www.sciencedirect.com www.sciencedirect.com
    Tumor cells dictate anti-tumor immune responses by altering pyruvate utilization and succinate signaling in CD8+ T cells
    1
    1. scibot 13 Jul 2022
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      DOI: 10.1016/j.cmet.2022.06.008

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    sciencedirect.com/science/article/pii/S1550413122002285
  47. Jun 2022
  48. www.sciencedirect.com www.sciencedirect.com
    Poroptosis: a form of cell death depending on plasma membrane nanopores formation
    1
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      DOI: 10.1016/j.isci.2022.104481

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    sciencedirect.com/science/article/pii/S2589004222007520
  49. Apr 2022
  50. aacrjournals.org aacrjournals.org
    mDKN-01, a Novel Anti-DKK1 mAb, Enhances Innate Immune Responses in the Tumor Microenvironment
    1
    1. scibot 07 Apr 2022
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      DOI: 10.1158/1541-7786.MCR-20-0799

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    aacrjournals.org/mcr/article/19/4/717/672854/mDKN-01-a-Novel-Anti-DKK1-mAb-Enhances-Innate
  51. Feb 2022
  52. www.sciencedirect.com www.sciencedirect.com
    Flow cytometric analysis of CD4+ T cell reactivation following anti-PD1 immunotherapy in a transgenic mouse model
    2
    1. scibot 11 Feb 2022
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      DOI: 10.1016/j.xpro.2022.101161

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    2. scibot 09 Feb 2022
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      DOI: 10.1016/j.xpro.2022.101161

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    sciencedirect.com/science/article/pii/S2666166722000417
  53. Nov 2021
  54. www.sciencedirect.com www.sciencedirect.com
    Reprogramming NK cells and macrophages via combined antibody and cytokine therapy primes tumors for elimination by checkpoint blockade
    1
    1. scibot 24 Nov 2021
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      DOI: 10.1016/j.celrep.2021.110021

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    sciencedirect.com/science/article/pii/S2211124721015035
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Glut1 expression in tumor-associated neutrophils promotes lung cancer growth and resistance to radiotherapy
    1
    1. scibot 05 Nov 2021
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      DOI: 10.1158/0008-5472.CAN-20-2870

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  56. Oct 2021
  57. clincancerres.aacrjournals.org clincancerres.aacrjournals.org
    Rapid Serial Immunoprofiling of the Tumor Immune Microenvironment by Fine Needle Sampling
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      DOI: 10.1158/1078-0432.CCR-21-1252

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  58. Sep 2021
  59. www.sciencedirect.com www.sciencedirect.com
    Antigen dominance hierarchies shape TCF1+ progenitor CD8 T cell phenotypes in tumors
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      DOI: 10.1016/j.cell.2021.08.020

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  60. www.sciencedirect.com www.sciencedirect.com
    Antigen and checkpoint receptor engagement recalibrates T cell receptor signal strength
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      DOI: 10.1016/j.immuni.2021.08.020

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  61. www.sciencedirect.com www.sciencedirect.com
    Activating a collaborative innate-adaptive immune response to control metastasis
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      DOI: 10.1016/j.ccell.2021.08.005

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  62. Aug 2021
  63. www.sciencedirect.com www.sciencedirect.com
    Commensal Clostridiales strains mediate effective anti-cancer immune response against solid tumors
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  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Immune mechanisms orchestrate tertiary lymphoid structures in tumors via cancer-associated fibroblasts
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      DOI: 10.1016/j.celrep.2021.109422

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  65. www.sciencedirect.com www.sciencedirect.com
    The CD155/TIGIT axis promotes and maintains immune evasion in neoantigen-expressing pancreatic cancer
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      DOI: 10.1016/j.ccell.2021.07.007

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  66. Jul 2021
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    Defining T Cell States Associated with Response to Checkpoint Immunotherapy in Melanoma
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      DOI: 10.1016/j.cell.2018.10.038

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  68. Jun 2021
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    Expansion of tumor-associated Treg cells upon disruption of a CTLA-4-dependent feedback loop
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      DOI: 10.1016/j.cell.2021.05.027

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  70. May 2021
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    Targeting KDM4A epigenetically activates tumor-cell-intrinsic immunity by inducing DNA replication stress
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      DOI: 10.1016/j.molcel.2021.02.038

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  72. Dec 2020
  73. www.sciencedirect.com www.sciencedirect.com
    FBXO44 promotes DNA replication-coupled repetitive element silencing in cancer cells
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      DOI: 10.1016/j.cell.2020.11.042

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    sciencedirect.com/science/article/pii/S0092867420316147
  74. Sep 2020
  75. www.sciencedirect.com www.sciencedirect.com
    The PD-1 Pathway Regulates Development and Function of Memory CD8+ T Cells following Respiratory Viral Infection
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      DOI: 10.1016/j.celrep.2020.107827

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  76. Jan 2020
  77. www.sciencedirect.com www.sciencedirect.com
    UVB-Induced Tumor Heterogeneity Diminishes Immune Response in Melanoma
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      RRID:AB_2687796

      DOI: 10.1016/j.cell.2019.08.032

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  78. www.sciencedirect.com www.sciencedirect.com
    Restricting Glycolysis Preserves T Cell Effector Functions and Augments Checkpoint Therapy
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      DOI: 10.1016/j.celrep.2019.08.068

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    sciencedirect.com/science/article/pii/S2211124719311234
  79. www.sciencedirect.com www.sciencedirect.com
    Treg Cells Promote the SREBP1-Dependent Metabolic Fitness of Tumor-Promoting Macrophages via Repression of CD8+ T Cell-Derived Interferon-γ
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      RRID:AB_2687796

      DOI: 10.1016/j.immuni.2019.06.017

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  80. www.sciencedirect.com www.sciencedirect.com
    PD-L1:CD80 Cis-Heterodimer Triggers the Co-stimulatory Receptor CD28 While Repressing the Inhibitory PD-1 and CTLA-4 Pathways
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      RRID:AB_2687796

      DOI: 10.1016/j.immuni.2019.11.003

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  81. www.sciencedirect.com www.sciencedirect.com
    RIP1 Kinase Drives Macrophage-Mediated Adaptive Immune Tolerance in Pancreatic Cancer
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    1. scibot 13 Jan 2020
      RRID:AB_2687796

      DOI: 10.1016/j.ccell.2018.10.006

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    sciencedirect.com/science/article/pii/S1535610818304720
  82. Nov 2018
  83. www.sciencedirect.com www.sciencedirect.com
    Urea Cycle Dysregulation Generates Clinically Relevant Genomic and Biochemical Signatures
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