39 Matching Annotations
  1. Apr 2024
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    Nuclear RNA homeostasis promotes systems-level coordination of cell fate and senescence
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    1. scibot 18 Apr 2024
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      DOI: 10.1016/j.stem.2024.03.015

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    sciencedirect.com/science/article/pii/S1934590924000961
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    SAFB restricts contact domain boundaries associated with L1 chimeric transcription
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    1. scibot 11 Apr 2024
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    sciencedirect.com/science/article/pii/S1097276524002314
  4. Mar 2024
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    Transcription elongation defects link oncogenic SF3B1 mutations to targetable alterations in chromatin landscape
    1
    1. scibot 29 Mar 2024
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    sciencedirect.com/science/article/pii/S1097276524001758
  6. Dec 2023
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    Collisions of RNA polymerases behind the replication fork promote alternative RNA splicing in newly replicated chromatin
    1
    1. scibot 29 Dec 2023
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    sciencedirect.com/science/article/pii/S1097276523010122
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    Pluripotency state transition of embryonic stem cells requires the turnover of histone chaperone FACT on chromatin
    1
    1. scibot 21 Dec 2023
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    sciencedirect.com/science/article/pii/S2589004223026147
  9. Oct 2023
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    Protocol for rapidly inducing genome-wide RNA Pol II hyperphosphorylation by selectively disrupting INTAC phosphatase activity
    2
    1. scibot 22 Oct 2023
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      DOI: 10.1016/j.xpro.2023.102640

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    2. scibot 22 Oct 2023
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      DOI: 10.1016/j.xpro.2023.102640

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    sciencedirect.com/science/article/pii/S266616672300607X
  11. Jul 2023
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    Chromatin regulation of transcriptional enhancers and cell fate by the Sotos syndrome gene NSD1
    1
    1. scibot 06 Jul 2023
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    sciencedirect.com/science/article/pii/S1097276523004306
  13. Apr 2023
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    A hyper-quiescent chromatin state formed during aging is reversed by regeneration
    1
    1. scibot 29 Apr 2023
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      DOI: 10.1016/j.molcel.2023.04.005

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    sciencedirect.com/science/article/pii/S1097276523002496
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    RNA Pol II preferentially regulates ribosomal protein expression by trapping disassociated subunits
    1
    1. scibot 27 Apr 2023
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      DOI: 10.1016/j.molcel.2023.02.028

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    sciencedirect.com/science/article/pii/S1097276523001557
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    INTAC endonuclease and phosphatase modules differentially regulate transcription by RNA polymerase II
    1
    1. scibot 20 Apr 2023
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      DOI: 10.1016/j.molcel.2023.03.022

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    sciencedirect.com/science/article/pii/S1097276523002125
  17. Dec 2022
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    SETD1A regulates transcriptional pause release of heme biosynthesis genes in leukemia
    1
    1. scibot 01 Dec 2022
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      DOI: 10.1016/j.celrep.2022.111727

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    sciencedirect.com/science/article/pii/S2211124722016059
  19. Nov 2022
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    Acute depletion of human core nucleoporin reveals direct roles in transcription control but dispensability for 3D genome organization
    1
    1. scibot 03 Nov 2022
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      DOI: 10.1016/j.celrep.2022.111576

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    sciencedirect.com/science/article/pii/S2211124722014371
  21. Sep 2022
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    Targeted protein degradation reveals RNA Pol II heterogeneity and functional diversity
    1
    1. scibot 16 Sep 2022
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      DOI: 10.1016/j.molcel.2022.08.023

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    sciencedirect.com/science/article/pii/S1097276522008127
  23. Aug 2022
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    SPT6 functions in transcriptional pause/release via PAF1C recruitment
    1
    1. scibot 10 Aug 2022
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      DOI: 10.1016/j.molcel.2022.06.037

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    sciencedirect.com/science/article/pii/S1097276522006554
  25. Jun 2022
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    Counteracting chromatin effects of a splicing-correcting antisense oligonucleotide improves its therapeutic efficacy in spinal muscular atrophy
    1
    1. scibot 10 Jun 2022
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      DOI: 10.1016/j.cell.2022.04.031

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    sciencedirect.com/science/article/pii/S0092867422005293
  27. Apr 2022
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    RPAP2 regulates a transcription initiation checkpoint by inhibiting assembly of pre-initiation complex
    1
    1. scibot 27 Apr 2022
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      DOI: 10.1016/j.celrep.2022.110732

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    sciencedirect.com/science/article/pii/S2211124722004934
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    Novel role of UHRF1 in the epigenetic repression of the latent HIV-1
    1
    1. scibot 20 Apr 2022
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      DOI: 10.1016/j.ebiom.2022.103985

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    sciencedirect.com/science/article/pii/S2352396422001694
  30. Sep 2021
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    SPT5 stabilizes RNA polymerase II, orchestrates transcription cycles, and maintains the enhancer landscape
    1
    1. scibot 17 Sep 2021
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      DOI: 10.1016/j.molcel.2021.08.029

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    sciencedirect.com/science/article/pii/S1097276521006961
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    SPT5 stabilization of promoter-proximal RNA polymerase II
    1
    1. scibot 04 Sep 2021
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      DOI: 10.1016/j.molcel.2021.08.006

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    sciencedirect.com/science/article/pii/S1097276521006468
  33. Aug 2021
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SCAF4 and SCAF8, mRNA Anti-Terminator Proteins
    1
    1. scibot 14 Aug 2021
      RRID:AB_2687876

      DOI: 10.1016/j.cell.2019.04.038

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    ncbi.nlm.nih.gov/pmc/articles/PMC6579486/
  35. www.eneuro.org www.eneuro.org
    Untitled document
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    1. scibot 11 Aug 2021
      RRID:AB_2687876

      DOI: 10.1523/ENEURO.0040-17.2017

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    eneuro.org/content/4/4/eneuro.0040-17.2017
  36. Jun 2021
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    A role for the Cockayne Syndrome B (CSB)-Elongin ubiquitin ligase complex in signal-dependent RNA polymerase II transcription
    1
    1. scibot 12 Jun 2021
      14958S

      DOI: 10.1016/j.jbc.2021.100862

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    sciencedirect.com/science/article/pii/S0021925821006621
  38. Apr 2021
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    Complex-dependent histone acetyltransferase activity of KAT8 determines its role in transcription and cellular homeostasis
    1
    1. scibot 19 Apr 2021
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      DOI: 10.1016/j.molcel.2021.02.012

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    sciencedirect.com/science/article/pii/S1097276521000988
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    Topoisomerase IIα represses transcription by enforcing promoter-proximal pausing
    1
    1. scibot 14 Apr 2021
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      DOI: 10.1016/j.celrep.2021.108977

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    sciencedirect.com/science/article/pii/S2211124721002916
  41. Feb 2021
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    Distinct properties and functions of CTCF revealed by a rapidly inducible degron system
    1
    1. scibot 25 Feb 2021
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      DOI: 10.1016/j.celrep.2021.108783

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    sciencedirect.com/science/article/pii/S2211124721000966
  43. Dec 2020
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    CDK8 Fine-Tunes IL-6 Transcriptional Activities by Limiting STAT3 Resident Time at the Gene Loci
    1
    1. scibot 24 Dec 2020
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      DOI: 10.1016/j.celrep.2020.108545

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    sciencedirect.com/science/article/pii/S2211124720315345
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    WDR82/PNUTS-PP1 Prevents Transcription-Replication Conflicts by Promoting RNA Polymerase II Degradation on Chromatin
    1
    1. scibot 07 Dec 2020
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      DOI: 10.1016/j.celrep.2020.108469

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    sciencedirect.com/science/article/pii/S2211124720314583
  46. Sep 2020
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    Chromatin Hyperacetylation Impacts Chromosome Folding by Forming a Nuclear Subcompartment
    1
    1. scibot 11 Sep 2020
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      DOI: 10.1016/j.molcel.2020.03.018

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    sciencedirect.com/science/article/pii/S1097276520301866
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    Regulation of the RNAPII Pool Is Integral to the DNA Damage Response
    1
    1. scibot 04 Sep 2020
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      DOI: 10.1016/j.cell.2020.02.009

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    sciencedirect.com/science/article/pii/S0092867420301537
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    The Human Integrator Complex Facilitates Transcriptional Elongation by Endonucleolytic Cleavage of Nascent Transcripts
    1
    1. scibot 03 Sep 2020
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      DOI: 10.1016/j.celrep.2020.107917

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    sciencedirect.com/science/article/pii/S2211124720308986
  50. Jan 2020
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    TRIM32/USP11 Balances ARID1A Stability and the Oncogenic/Tumor-Suppressive Status of Squamous Cell Carcinoma
    1
    1. scibot 13 Jan 2020
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      DOI: 10.1016/j.celrep.2019.12.017

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    sciencedirect.com/science/article/pii/S2211124719316675
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    A Functional Link between Nuclear RNA Decay and Transcriptional Control Mediated by the Polycomb Repressive Complex 2
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      DOI: 10.1016/j.celrep.2019.10.011

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    sciencedirect.com/science/article/pii/S2211124719313117
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      DOI: 10.1016/j.cell.2019.04.038

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    sciencedirect.com/science/article/pii/S009286741930457X
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    A CHAF1B-Dependent Molecular Switch in Hematopoiesis and Leukemia Pathogenesis
    1
    1. scibot 12 Jan 2020
      RRID:AB_2687876

      DOI: 10.1016/j.ccell.2018.10.004

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    sciencedirect.com/science/article/pii/S1535610818304707
  55. Nov 2018
  56. www.sciencedirect.com www.sciencedirect.com
    Targeting Processive Transcription Elongation via SEC Disruption for MYC-Induced Cancer Therapy
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    sciencedirect.com/science/article/pii/S009286741831239X
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    1. scibot 05 Nov 2018
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    ncbi.nlm.nih.gov/pmc/articles/PMC6039721/
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    The Nucleosome Remodeling and Deacetylation Complex Modulates Chromatin Structure at Sites of Active Transcription to Fine-Tune Gene Expression
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    1. scibot 05 Nov 2018
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      Curator: @evieth

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    sciencedirect.com/science/article/pii/S1097276518304453
  59. Nov 2017
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Histone Hypervariants H2A.Z.1 and H2A.Z.2 Play Independent and Context-Specific Roles in Neuronal Activity-Induced Transcription of Arc/Arg3.1 and Other Immediate Early Genes
    1
    1. scibot 08 Nov 2017
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    ncbi.nlm.nih.gov/pmc/articles/PMC5569379/