22 Matching Annotations
  1. Last 7 days
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    Scaffolding-dependent CASP1 constrains excessive cell-intrinsic inflammatory signaling in leukemia
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    sciencedirect.com/science/article/pii/S2451945625003952
  3. Nov 2025
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Evasion of CARD8 activation during HIV-1 assembly
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    pmc.ncbi.nlm.nih.gov/articles/PMC12609157/
  5. Oct 2025
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Inflammasome-independent IL-1β activation via staphopain A protease of Staphylococcus aureus[image]
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    pmc.ncbi.nlm.nih.gov/articles/PMC12528902/
  7. Jul 2025
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A Potent Inhibitor of Caspase-8 Based on the IL-18 Tetrapeptide Sequence Reveals Shared Specificities between Inflammatory and Apoptotic Initiator Caspases
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    pmc.ncbi.nlm.nih.gov/articles/PMC12371506/
  9. Jan 2025
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    FUBP3 mediates the amyloid-β-induced neuronal NLRP3 expression
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    pmc.ncbi.nlm.nih.gov/articles/PMC11691456/
  11. Dec 2024
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The ribotoxic stress response drives acute inflammation, cell death, and epidermal thickening in UV-irradiated skin in vivo
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    pmc.ncbi.nlm.nih.gov/articles/PMC11671030/
  13. Sep 2024
  14. www.sciencedirect.com www.sciencedirect.com
    Small-molecule GSDMD agonism in tumors stimulates antitumor immunity without toxicity
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    sciencedirect.com/science/article/pii/S0092867424008985
  15. Jul 2024
  16. www.sciencedirect.com www.sciencedirect.com
    The hydrophobicity of the CARD8 N-terminus tunes inflammasome activation
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    sciencedirect.com/science/article/pii/S245194562400223X
  17. Apr 2024
  18. 52.53.155.43 52.53.155.43
    The activation of LBH-CRYAB signaling promotes cardiac protection against ischemia-reperfusion injury by inhibiting apoptosis and ferroptosis
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    52.53.155.43/e4a741173d4beb6859350a39a8e5091b3ba2fb02/1-s2.0-S2589004224007314-main-html.html
  19. Mar 2024
  20. www.sciencedirect.com www.sciencedirect.com
    The CARD8 inflammasome dictates HIV/SIV pathogenesis and disease progression
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    sciencedirect.com/science/article/pii/S009286742400117X
  21. Dec 2023
  22. www.sciencedirect.com www.sciencedirect.com
    The tetrapeptide sequence of IL-18 and IL-1β regulates their recruitment and activation by inflammatory caspases
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    sciencedirect.com/science/article/pii/S2211124723015930
  23. Jan 2023
  24. www.sciencedirect.com www.sciencedirect.com
    Protein folding stress potentiates NLRP1 and CARD8 inflammasome activation
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    sciencedirect.com/science/article/pii/S2211124722018691
  25. www.sciencedirect.com www.sciencedirect.com
    The NLRP1 and CARD8 inflammasomes detect reductive stress
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    sciencedirect.com/science/article/pii/S2211124722018708
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    Pyruvate dehydrogenase kinase supports macrophage NLRP3 inflammasome activation during acute inflammation
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    sciencedirect.com/science/article/pii/S2211124722018423
  27. Jul 2022
  28. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15904
  29. May 2021
  30. www.cell.com www.cell.com
    Dipeptidyl peptidase 9 sets a threshold for CARD8 inflammasome formation by sequestering its active C-terminal fragment
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    cell.com/immunity/fulltext/S1074-7613(21)00186-2
  31. www.sciencedirect.com www.sciencedirect.com
    Virus-mediated inactivation of anti-apoptotic Bcl-2 family members promotes Gasdermin-E-dependent pyroptosis in barrier epithelial cells
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    sciencedirect.com/science/article/pii/S1074761321001746
  32. Apr 2021
  33. www.sciencedirect.com www.sciencedirect.com
    Apaf-1 Pyroptosome Senses Mitochondrial Permeability Transition
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    sciencedirect.com/science/article/pii/S1550413120306537
  34. Oct 2020
  35. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Activation of the CARD8 Inflammasome Requires a Disordered Region
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    pubmed.ncbi.nlm.nih.gov/33053349/
  36. Nov 2018
  37. www.sciencedirect.com www.sciencedirect.com
    The Pore-Forming Protein Gasdermin D Regulates Interleukin-1 Secretion from Living Macrophages
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    sciencedirect.com/science/article/pii/S1074761317305149
  38. Nov 2017
  39. www.sciencedirect.com www.sciencedirect.com
    Pyroptosis and Apoptosis Pathways Engage in Bidirectional Crosstalk in Monocytes and Macrophages
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    sciencedirect.com/science/article/pii/S2451945617300922