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  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Protein profile of mouse endolymph suggests a role in controlling cochlear homeostasis
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    1. scibot 21 Nov 2024
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  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SIRT3 differentially regulates lysine benzoylation from SIRT2 in mammalian cells
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  4. Nov 2024
  5. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Single-cell sequencing combined with transcriptomics and in vivo and in vitro analysis reveals the landscape of ferroptosis in myocardial ischemia–reperfusion injury
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    1. scibot 14 Nov 2024
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    ZDHHC3-mediated SCAP S-acylation promotes cholesterol biosynthesis and tumor immune escape in hepatocellular carcinoma
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  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Clopidogrel ameliorates high-fat diet-induced hepatic steatosis in mice through activation of the AMPK signaling pathway and beyond
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  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    NOSTRIN is involved in benign prostatic hyperplasia via inhibition of proliferation, oxidative stress, and inflammation in prostate epithelial cells
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    Beyond Glycolysis: Aldolase A Is a Novel Effector in Reelin-Mediated Dendritic Development
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  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Grb7 Ablation in Mice Improved Glycemic Control, Enhanced Insulin Signaling, and Increased Abdominal fat Mass in Females
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  11. Oct 2024
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The AGEs/RAGE Signaling Pathway Regulates NLRP3-Mediated Neuronal Pyroptosis After MCAO Injury in Lepr−/− Obese Rats
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  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sirtuin 1/sirtuin 3 are robust lysine delactylases and sirtuin 1-mediated delactylation regulates glycolysis
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    1. scibot 05 Oct 2024
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    Compound (E)-2-(3,4-dihydroxystyryl)-3-hydroxy-4H-pyran-4-one downregulation of Galectin-3 ameliorates Aβ pathogenesis-induced neuroinflammation in 5 × FAD mice
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  15. Sep 2024
  16. onlinelibrary.wiley.com onlinelibrary.wiley.com
    In utero morphological and functional properties of bovine trophoblastic vesicles
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    1. scibot 27 Sep 2024
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    Targeting NAT10 inhibits osteosarcoma progression via ATF4/ASNS-mediated asparagine biosynthesis
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    Silencing of TXNIP attenuates oxidative stress injury in HEI-OC1 by inhibiting the activation of NLRP3 and NF-κB
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  19. Aug 2024
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hyperglycemia induced cathepsin L maturation linked to diabetic comorbidities and COVID-19 mortality
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    Nuclear HMGB1 is critical for CD8 T cell IFN-γ production and anti-tumor immunity
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    IFI-16 inhibition attenuates myocardial remodeling following myocardial infarction
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    Glycometabolic reprogramming-induced XRCC1 lactylation confers therapeutic resistance in ALDH1A3-overexpressing glioblastoma
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    Hub genes and key pathways of traumatic brain injury:... : Neural Regeneration Research
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    journals.lww.com/nrronline/fulltext/2025/09000/enhanced_autophagic_clearance_of_amyloid___via.25.aspx
  25. cellandbioscience.biomedcentral.com cellandbioscience.biomedcentral.com
    β-adrenergic receptor inhibition enhances oncolytic herpes virus propagation through STAT3 activation in gastric cancer
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    The V-ATPase/ATG16L1 axis is controlled by the V1H subunit
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    sciencedirect.com/science/article/pii/S1097276524005793
  27. Jul 2024
  28. link.springer.com link.springer.com
    CircARAP2 controls sMICA-induced NK cell desensitization by erasing CTCF/PRC2-induced suppression in early endosome marker RAB5A
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  29. www.cell.com www.cell.com
    A pro-metastatic tRNA fragment drives aldolase A oligomerization to enhance aerobic glycolysis in lung adenocarcinoma
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    cell.com/cell-reports/abstract/S2211-1247(24)00879-9
  30. 52.53.155.43 52.53.155.43
    Magnetic-vortex nanodonuts enhance ferroptosis effect of tumor ablation through an integrated imaging-guided hyperthermia/radiosensitization strategy
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    52.53.155.43/b6d4079224da0d4e406187caee6b5b82e5a1b73e/1-s2.0-S2589004224017589-main-html.html
  31. link.springer.com link.springer.com
    Calorie Restriction Attenuates Memory Impairment and Reduces Neuroinflammation in Obese Aged Rats
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  32. www.sciencedirect.com www.sciencedirect.com
    Astrocytic LRP1 enables mitochondria transfer to neurons and mitigates brain ischemic stroke by suppressing ARF1 lactylation
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    Bombinin-BO1 induces hepatocellular carcinoma cell-cycle arrest and apoptosis via the HSP90A-Cdc37-CDK1 axis
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  34. Jun 2024
  35. link.springer.com link.springer.com
    Capturing acyl–enzyme intermediates with genetically encoded 2,3-diaminopropionic acid for hydrolase substrate identification
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      DOI: 10.1038/s41596-024-01006-x

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    Development of a PCSK9-targeted nanoparticle vaccine to effectively decrease the hypercholesterolemia
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    sciencedirect.com/science/article/pii/S2666379124003185
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    Nicotinamide metabolism face-off between macrophages and fibroblasts manipulates the microenvironment in gastric cancer
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  38. May 2024
  39. www.sciencedirect.com www.sciencedirect.com
    Protocol for identifying OXCT1-mediated LACTB succinylation sites in vitro
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    sciencedirect.com/science/article/pii/S2666166724002533
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    CRACD loss induces neuroendocrine cell plasticity of lung adenocarcinoma
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    sciencedirect.com/science/article/pii/S2211124724006144
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mecp2 fine-tunes quiescence exit by targeting nuclear receptors
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      DOI: 10.7554/eLife.89912

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    ncbi.nlm.nih.gov/pmc/articles/PMC11095939/
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tabersonine enhances cisplatin sensitivity by modulating Aurora kinase A and suppressing epithelial–mesenchymal transition in triple-negative breast cancer
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      DOI: 10.1080/13880209.2024.2351934

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    ncbi.nlm.nih.gov/pmc/articles/PMC11095288/
  43. Apr 2024
  44. www.sciencedirect.com www.sciencedirect.com
    Endothelial progenitor cells control remodeling of uterine spiral arteries for the establishment of utero-placental circulation
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  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HDAC10 inhibition represses melanoma cell growth and BRAF inhibitor resistance via upregulating SPARC expression
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      DOI: 10.1093/narcan/zcae018

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    ncbi.nlm.nih.gov/pmc/articles/PMC11034028/
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    p38 MAPK inhibitor SB202190 suppresses ferroptosis in the glutamate-induced retinal excitotoxicity glaucoma model
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    DDX20 is required for cell-cycle reentry of prospermatogonia and establishment of spermatogonial stem cell pool during testicular development in mice
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    Targeting high circDNA2v levels in colorectal cancer induces cellular senescence and elicits an anti-tumor secretome
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    The crosstalk between macrophages and cancer cells potentiates pancreatic cancer cachexia
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    The deubiquitinase cofactor UAF1 interacts with USP1 and plays an essential role in spermiogenesis
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    Dimethyl fumarate covalently modifies Cys673 of NLRP3 to exert anti-inflammatory effects
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    Systematic HOIP interactome profiling reveals critical roles of linear ubiquitination in tissue homeostasis
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    Genetic or pharmacologic blockade of mPGES-2 attenuates renal lipotoxicity and diabetic kidney disease by targeting Rev-Erbα/FABP5 signaling
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    Metaplastic regeneration in the mouse stomach requires a reactive oxygen species pathway
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    Hippo-signaling-controlled MHC class I antigen processing and presentation pathway potentiates antitumor immunity
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    Bile acids modified by the intestinal microbiota promote colorectal cancer growth by suppressing CD8+ T cell effector functions
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    Dietary protein restriction regulates skeletal muscle fiber metabolic characteristics associated with the FGF21-ERK1/2 pathway
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    Aging-induced tRNAGlu-derived fragment impairs glutamate biosynthesis by targeting mitochondrial translation-dependent cristae organization
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    Helicobacter pylori CagA-mediated ether lipid biosynthesis promotes ferroptosis susceptibility in gastric cancer
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    Human YKT6 forms priming complex with STX17 and SNAP29 to facilitate autophagosome-lysosome fusion
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    HDAC10 blockade upregulates SPARC expression thereby repressing melanoma cell growth and BRAF inhibitor resistance
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    Investigating HMGB1 as a Potential Serum Biomarker for Early Diabetic Nephropathy Monitoring by Quantitative Proteomics
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    Serine synthesis sustains macrophage IL-1β production via NAD+-dependent protein acetylation
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    Nucleoporin Seh1 controls murine neocortical development via transcriptional repression of p21 in neural stem cells
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    Exercise enhances placental labyrinth trophoblast development by activation of PGC-1α and FNDC5/irisin
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    OXCT1 functions as a succinyltransferase, contributing to hepatocellular carcinoma via succinylating LACTB
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    CHTOP Alleviates Cerebral Ischemia/Reperfusion-Induced Injury by Regulating RNA Alternative Splicing
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    Down-regulating nuclear factor of activated T cells 1 alleviates cognitive deficits in a mouse model of sepsis-associated encephalopathy, possibly by stimulating hippocampal neurogenesis
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    Hexamethylene amiloride synergizes with venetoclax to induce lysosome-dependent cell death in acute myeloid leukemia
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    YTHDF3 modulates the Cbln1 level by recruiting BTG2 and is implicated in the impaired cognition of prenatal hypoxia offspring
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    Metabolic regulation of homologous recombination repair by MRE11 lactylation
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    Choroid plexus mast cells drive tumor-associated hydrocephalus
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    Upregulation of UHRF1 Promotes PINK1-mediated Mitophagy to Alleviates Ferroptosis in Diabetic Nephropathy
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    Autophagy is involved in degradation of AQP1 in response to an acute decrement in tonicity
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    A bacteria-derived tetramerized protein ameliorates nonalcoholic steatohepatitis in mice via binding and relocating acetyl-coA carboxylase
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    ZHX2 emerges as a negative regulator of mitochondrial oxidative phosphorylation during acute liver injury
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    Targeting PRMT1-mediated SRSF1 methylation to suppress oncogenic exon inclusion events and breast tumorigenesis
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    AKAP150 from Nucleus Accumbens Dopamine D1 and D2 Receptor-Expressing Medium Spiny Neurons Regulates Morphine Withdrawal
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    Culin5 aggravates hypoxic pulmonary hypertension by activating TRAF6/NF-κB/HIF-1α/VEGF
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    Focused Low-Intensity Pulsed Ultrasound Alleviates Osteoarthritis via Restoring Impaired FUNDC1-Mediated Mitophagy
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    Identification of KLHDC2 as an efficient proximity-induced degrader of K-RAS, STK33, β-catenin, and FoxP3
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    The Scap-SREBP1-S1P/S2P lipogenesis signal orchestrates the homeostasis and spatiotemporal activation of NF-κB
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    MRPL12-ANT3 interaction involves in acute kidney injury via regulating MPTP of tubular epithelial cells
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    Potential targets and mechanisms of photobiomodulation for... : Neural Regeneration Research
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    Combination therapy with ultrasound and 2D nanomaterials promotes recovery after spinal cord injury via Piezo1 downregulation
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    SIM imaging resolves endocytosis of SARS-CoV-2 spike RBD in living cells
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    PPT1 Regulation Of HSP90α Depalmitoylation Participates In The Pathogenesis Of Hyperandrogenism
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  148. Feb 2023
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    iTRAQ-based proteomic analysis unveils ACSL4 as a novel potential regulator of human endometrial receptivity
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    Osmoadaptive GLP-1R signalling in hypothalamic neurones inhibits antidiuretic hormone synthesis and release
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    Transcriptome analysis highlights the role of ferroptosis in palmitic acid–induced endothelial dysfunction
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  153. Jan 2023
  154. journals.lww.com journals.lww.com
    Emodin attenuates inflammation and demyelination in... : Neural Regeneration Research
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    SLC7A14 imports GABA to lysosomes and impairs hepatic insulin sensitivity via inhibiting mTORC2
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    Targeting BCAT1 combined with α-ketoglutarate triggers metabolic synthetic lethality in glioblastoma
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    The deubiquitinase OTUD1 noncanonically suppresses Akt activation through its N-terminal intrinsically disordered region
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  160. Dec 2022
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    Tim-4 reprograms cholesterol metabolism to suppress antiviral innate immunity by disturbing the Insig1-SCAP interaction in macrophages
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    NVP-BHG712 against postmenopausal osteoporosis in mice by targeting Cathepsin K
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    Leukemia inhibitory factor is a therapeutic target for renal interstitial fibrosis
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    Mobilizing phospholipids on tumor plasma membrane implicates phosphatidylserine externalization blockade for cancer immunotherapy
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  175. Oct 2022
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    Cortisol stimulates local progesterone withdrawal through induction of AKR1C1 in human amnion fibroblasts at parturition
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    Vascular restenosis reduction with platelet membrane coated nanoparticle directed M2 macrophage polarization
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    Argininosuccinate lyase drives activation of mutant TERT promoter in glioblastomas
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    Androgen receptor suppresses β-adrenoceptor-mediated CREB activation and thermogenesis in brown adipose tissue of male mice
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    Molecular mechanism of RIPK1 and caspase-8 in homeostatic type I interferon production and regulation
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  181. journals.lww.com journals.lww.com
    Necroptosis plays a crucial role in the exacerbation of... : Neural Regeneration Research
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    FBXL6 depletion restrains clear cell renal cell carcinoma progression
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  183. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Induced retinal pigment epithelial cells with anti-epithelial-to-mesenchymal transition ability delay retinal degeneration
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  184. Sep 2022
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    CTCF DNA-binding domain undergoes dynamic and selective protein–protein interactions
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  186. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Alpha-Momorcharin Inhibits Proinflammatory Cytokine Expression by M1 Macrophages but Not Anti-Inflammatory Cytokine Expression by M2 Macrophages
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  187. Aug 2022
  188. journals.lww.com journals.lww.com
    Chronic spinal cord compression associated with... : Neural Regeneration Research
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  189. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Novel ER Stress Mediator TMTC3 Promotes Squamous Cell Carcinoma Progression by Activating GRP78/PERK Signaling Pathway
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  190. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NF-κB and AP-1 are required for the lipopolysaccharide-induced expression of MCP-1, CXCL1, and Cx43 in cultured rat dorsal spinal cord astrocytes
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  191. Jul 2022
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    Aberrant human ClpP activation disturbs mitochondrial proteome homeostasis to suppress pancreatic ductal adenocarcinoma
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  193. nyaspubs.onlinelibrary.wiley.com nyaspubs.onlinelibrary.wiley.com
    Identification by RNA-Seq of let-7 clusters as prenatal biomarkers for nonsyndromic cleft lip with palate
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  194. Jun 2022
  195. 52.53.155.43 52.53.155.43
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    The Role of Ciliopathy-Associated Type 3 Adenylyl Cyclase in Infanticidal Behavior in Virgin Adult Male Mice
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  197. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BMP4 Exerts Anti-Neurogenic Effect via Inducing Id3 during Aging
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  198. May 2022
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    SM22α-lineage niche cells regulate intramembranous bone regeneration via PDGFRβ-triggered hydrogen sulfide production
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  200. Apr 2022
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    GM1 ganglioside modifies microglial and neuroinflammatory responses to α-synuclein in the rat AAV-A53T α-synuclein model of Parkinson's disease
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    An oxygen-adaptive interaction between SNHG12 and occludin maintains blood-brain barrier integrity
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  203. Mar 2022
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    Intestinal Tuft-2 cells exert antimicrobial immunity via sensing bacterial metabolite N-undecanoylglycine
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  205. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    TIMP2 mediates endoplasmic reticulum stress contributing to sepsis-induced acute kidney injury
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  206. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    VPS28 regulates brain vasculature by controlling neuronal VEGF trafficking through extracellular vesicle secretion
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    Single-cell sequencing reveals the new existence form of dermal papilla cells in the hair follicle regeneration of cashmere goats
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    MYCT1 alters the glycogen shunt by regulating selective translation of RACK1-mediated enzymes
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    Urolithin A alleviates blood-brain barrier disruption and... : Neural Regeneration Research
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  210. Feb 2022
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    Dysregulated lipid metabolism blunts the sensitivity of cancer cells to EZH2 inhibitor
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    Suppression of premature transcription termination leads to reduced mRNA isoform diversity and neurodegeneration
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    The spliceosome component Usp39 controls B cell development by regulating immunoglobulin gene rearrangement
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    Nicotinamide N-methyltransferase ameliorates renal fibrosis by its metabolite 1-methylnicotinamide inhibiting the TGF-β1/Smad3 pathway
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  215. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The ALDH Family Contributes to Immunocyte Infiltration, Proliferation and Epithelial-Mesenchymal Transformation in Glioma
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    Proteomics Study Reveals the Anti-Depressive Mechanisms and the Compatibility Advantage of Chaihu-Shugan-San in a Rat Model of Chronic Unpredictable Mild Stress
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  217. Jan 2022
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    Structure and transport mechanism of the human cholesterol transporter ABCG1
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    Identification of G protein-coupled receptor 55 (GPR55) as a target of curcumin
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    4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone provokes progression from chronic pancreatitis to pancreatic intraepithelial neoplasia
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  221. Dec 2021
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    MIR337-3p Enhances Mycobacterial Pathogenicity Involving TLR4/MYD88 and STAT3 Signals, Impairing VDR Antimicrobial Response and Fast-Acting Immunity
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  223. Nov 2021
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    Cadherin-12 Regulates Neurite Outgrowth Through the PKA/Rac1/Cdc42 Pathway in Cortical Neurons
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  225. Oct 2021
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    Subtractive CRISPR screen identifies the ATG16L1/vacuolar ATPase axis as required for non-canonical LC3 lipidation
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    sciencedirect.com/science/article/pii/S2211124721013693
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    Phase separation drives RNA virus-induced activation of the NLRP6 inflammasome
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    1. scibot 22 Oct 2021
      RRID:AB_2687938

      DOI: 10.1016/j.cell.2021.09.032

      Resource: (Proteintech Cat# 66009-1-Ig, RRID:AB_2687938)

      Curator: @scibot

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    sciencedirect.com/science/article/pii/S0092867421011156
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    ADAR1 restricts ZBP1-mediated immune response and PANoptosis to promote tumorigenesis
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    1. scibot 21 Oct 2021
      RRID:AB_2687938

      DOI: 10.1016/j.celrep.2021.109858

      Resource: (Proteintech Cat# 66009-1-Ig, RRID:AB_2687938)

      Curator: @scibot

      SciCrunch record: RRID:AB_2687938

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    sciencedirect.com/science/article/pii/S2211124721013255