20 Matching Annotations
  1. Jun 2026
  2. www.sciencedirect.com www.sciencedirect.com
    The WEE1 inhibitor azenosertib broadly enhances efficacy of antibody-drug conjugates with topoisomerase I and microtubule inhibitor payloads
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    sciencedirect.com/science/article/pii/S2589004226017657
  3. Apr 2026
  4. 54.241.53.176 54.241.53.176
    2026.04.20.719456.full-html.html
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    54.241.53.176/6790efd246ed84de929dd028ff8d6465bfa7b2e6/2026.04.20.719456.full-html.html
  5. Aug 2025
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Azenosertib Is a Potent and Selective WEE1 Kinase Inhibitor with Broad Antitumor Activity Across a Range of Solid Tumors
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    pmc.ncbi.nlm.nih.gov/articles/PMC12314526/
  7. Jul 2025
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Histone Deacetylase Inhibitors Target DNA Replication Regulators and Replication Stress in Ewing Sarcoma Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12202856/
  9. Jun 2025
  10. 52.53.155.43 52.53.155.43
    PDF-html.html
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    52.53.155.43/6f95ee3860ed32eb2fc3447b03e264cd8239544f/PDF-html.html
  11. Apr 2025
  12. 52.53.155.43 52.53.155.43
    PDF-html.html
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    52.53.155.43/fb744ae1c201e64705cbba4fb67640ca74ff97a4/PDF-html.html
  13. Dec 2024
  14. www.cell.com www.cell.com
    UBA1 inhibition sensitizes cancer cells to PARP inhibitors
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    cell.com/cell-reports-medicine/fulltext/S2666-3791(24)00605-0
  15. Sep 2024
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    GCN2 is a determinant of the response to WEE1 kinase inhibition in small-cell lung cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11407228/
  17. Aug 2024
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Defining the KRAS- and ERK-dependent transcriptome in KRAS-mutant cancers
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    ncbi.nlm.nih.gov/pmc/articles/PMC11301402/
  19. Jul 2024
  20. www.science.org www.science.org
    Defining the KRAS- and ERK-dependent transcriptome in KRAS-mutant cancers
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    science.org/doi/10.1126/science.adk0775
  21. May 2024
  22. www.sciencedirect.com www.sciencedirect.com
    Targeting WEE1 enhances the antitumor effect of KRAS-mutated non-small cell lung cancer harboring TP53 mutations
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    sciencedirect.com/science/article/pii/S2666379124002702
  23. Nov 2022
  24. www.sciencedirect.com www.sciencedirect.com
    Targeted degradation of PCNA outperforms stoichiometric inhibition to result in programed cell death
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    sciencedirect.com/science/article/pii/S2451945622003592
  25. Oct 2022
  26. www.sciencedirect.com www.sciencedirect.com
    A mechanical G2 checkpoint controls epithelial cell division through E-cadherin-mediated regulation of Wee1-Cdk1
    1
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    sciencedirect.com/science/article/pii/S2211124722013250
  27. Jan 2022
  28. www.sciencedirect.com www.sciencedirect.com
    Compartmentalized control of Cdk1 drives mitotic spindle assembly
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    sciencedirect.com/science/article/pii/S2211124722000171
  29. Sep 2021
  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CCNE1 copy number is a biomarker for response to combination WEE1-ATR inhibition in ovarian and endometrial cancer models
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    pmc.ncbi.nlm.nih.gov/articles/PMC8484689/
  31. Aug 2021
  32. 52.53.155.43 52.53.155.43
    Synthesis and structure-activity relationships of targeted protein degraders for the understudied kinase NEK9
    1
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    52.53.155.43/660694af9c8e2ecacd48990031d316948592a872/1-s2.0-S2666246921000082-main-html.html
  33. Jul 2021
  34. www.sciencedirect.com www.sciencedirect.com
    Kinome-wide RNAi screening for mediators of ABT-199 resistance in breast cancer cells identifies Wee1 as a novel therapeutic target
    1
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    sciencedirect.com/science/article/pii/S1357272521001060
  35. May 2021
  36. www.sciencedirect.com www.sciencedirect.com
    DNA Damage Promotes TMPRSS2-ERG Oncoprotein Destruction and Prostate Cancer Suppression via Signaling Converged by GSK3β and WEE1
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    sciencedirect.com/science/article/pii/S1097276520305190
  37. Sep 2020
  38. mcb.asm.org mcb.asm.org
    Impact of losing hRpn13 Pru or UCHL5 on proteasome clearance of ubiquitinated proteins and RA190 cytotoxicity
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    mcb.asm.org/content/40/18/e00122-20
  39. Nov 2018
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Chemoproteomic Approach to Query the Degradable Kinome Using a Multi-kinase Degrader
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC6427047/