Hypothesis

21 Matching Annotations

Jan 2026
www.nature.com www.nature.com

PDZRN4 suppresses lung adenocarcinoma progression via inhibiting ubiquitin-mediated HIF-1A degradation

1
1. scibot 06 Jan 2026
  
  in Public
  
  RRID:AB_2713958
  
  DOI: 10.1038/s41388-025-03670-z
  
  Resource: (Cell Signaling Technology Cat# 48818, RRID:AB_2713958)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2713958
  
  What is this?
  
  RRID:AB_2713958
Visit annotations in context

Tags

RRID:AB_2713958

Annotators

scibot

URL

nature.com/articles/s41388-025-03670-z
Sep 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Pre-clinical Modeling of Navtemadlin Pharmacokinetics, Pharmacodynamics, and Efficacy in IDH-wildtype Glioblastoma

1
1. scibot 07 Sep 2025
  
  in Public
  
  RRID:AB_2713958
  
  DOI: 10.1158/1078-0432.CCR-25-0244
  
  Resource: (Cell Signaling Technology Cat# 48818, RRID:AB_2713958)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2713958
  
  What is this?
  
  RRID:AB_2713958
Visit annotations in context

Tags

RRID:AB_2713958

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12402800/
Jul 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The E3 ubiquitin ligase DTX3L and the deubiquitinase USP28 fine-tune DNA repair through mutual regulation of their protein levels

1
1. scibot 25 Jul 2025
  
  in Public
  
  RRID:AB_2713958
  
  DOI: 10.1016/j.isci.2025.112990
  
  Resource: (Cell Signaling Technology Cat# 48818, RRID:AB_2713958)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2713958
  
  What is this?
  
  RRID:AB_2713958
Visit annotations in context

Tags

RRID:AB_2713958

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12283747/
Feb 2025
www.sciencedirect.com www.sciencedirect.com

KRASG12D-driven pentose phosphate pathway remodeling imparts a targetable vulnerability synergizing with MRTX1133 for durable remissions in PDAC

1
1. scibot 20 Feb 2025
  
  in Public
  
  RRID:AB_2713958
  
  DOI: 10.1016/j.xcrm.2025.101966
  
  Resource: (Cell Signaling Technology Cat# 48818, RRID:AB_2713958)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2713958
  
  What is this?
  
  RRID:AB_2713958
Visit annotations in context

Tags

RRID:AB_2713958

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2666379125000394
Jun 2024
www.sciencedirect.com www.sciencedirect.com

TNF-NF-κB-p53 axis restricts in vivo survival of hPSC-derived dopamine neurons

1
1. scibot 21 Jun 2024
  
  in Public
  
  RRID:AB_2713958
  
  DOI: 10.1016/j.cell.2024.05.030
  
  Resource: (Cell Signaling Technology Cat# 48818, RRID:AB_2713958)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2713958
  
  What is this?
  
  RRID:AB_2713958
Visit annotations in context

Tags

RRID:AB_2713958

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0092867424005750
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

De novo TLK1 and MDM1 mutations in a patient with a neurodevelopmental disorder and immunodeficiency

1
1. scibot 14 Jun 2024
  
  in Public
  
  RRID:AB_2713958
  
  DOI: 10.1016/j.isci.2024.109984
  
  Resource: (Cell Signaling Technology Cat# 48818, RRID:AB_2713958)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2713958
  
  What is this?
  
  RRID:AB_2713958
Visit annotations in context

Tags

RRID:AB_2713958

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC11166698/
Mar 2024
www.sciencedirect.com www.sciencedirect.com

AurkA/TPX2 co-overexpression in nontransformed cells promotes genome instability through induction of chromosome mis-segregation and attenuation of the p53 signalling pathway

1
1. scibot 08 Mar 2024
  
  in Public
  
  RRID:AB_2713958
  
  DOI: 10.1016/j.bbadis.2024.167116
  
  Resource: (Cell Signaling Technology Cat# 48818, RRID:AB_2713958)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2713958
  
  What is this?
  
  RRID:AB_2713958
Visit annotations in context

Tags

RRID:AB_2713958

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0925443924001054
Nov 2023
www.sciencedirect.com www.sciencedirect.com

Replicative stress in gastroesophageal premalignancy is associated with chromosomal instability and sensitivity to DNA damage response inhibitors

1
1. scibot 04 Nov 2023
  
  in Public
  
  RRID:AB_2713958
  
  DOI: 10.1016/j.isci.2023.108169
  
  Resource: (Cell Signaling Technology Cat# 48818, RRID:AB_2713958)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2713958
  
  What is this?
  
  RRID:AB_2713958
Visit annotations in context

Tags

RRID:AB_2713958

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2589004223022460
Aug 2023
52.53.155.43 52.53.155.43

Synergy of 5-aminolevulinate supplement and CX3CR1 suppression promotes liver regeneration via elevated IGF-1 signaling

2
1. scibot 18 Aug 2023
  
  in Public
  
  RRID:AB_2713958
  
  DOI: 10.1016/j.celrep.2023.112984
  
  Resource: (Cell Signaling Technology Cat# 48818, RRID:AB_2713958)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2713958
  
  What is this?
  
  RRID:AB_2713958
2. scibot 16 Aug 2023
  
  in Public
  
  RRID:AB_2713958
  
  DOI: 10.1016/j.celrep.2023.112984
  
  Resource: (Cell Signaling Technology Cat# 48818, RRID:AB_2713958)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2713958
  
  What is this?
  
  RRID:AB_2713958
Visit annotations in context

Tags

RRID:AB_2713958

Annotators

scibot

URL

52.53.155.43/1bbe45cf5b4e78c7829bbc8558904ff45b580eb3/PIIS2211124723009956-html.html
www.sciencedirect.com www.sciencedirect.com

LHPP-mediated inorganic pyrophosphate hydrolysis-driven lysosomal acidification in astrocytes regulates adult neurogenesis

2
1. scibot 16 Aug 2023
  
  in Public
  
  RRID:AB_2713958
  
  DOI: 10.1016/j.celrep.2023.112975
  
  Resource: (Cell Signaling Technology Cat# 48818, RRID:AB_2713958)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2713958
  
  What is this?
  
  RRID:AB_2713958
2. scibot 16 Aug 2023
  
  in Public
  
  RRID:AB_2713958
  
  DOI: 10.1016/j.celrep.2023.112975
  
  Resource: (Cell Signaling Technology Cat# 48818, RRID:AB_2713958)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2713958
  
  What is this?
  
  RRID:AB_2713958
Visit annotations in context

Tags

RRID:AB_2713958

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124723009865
May 2023
www.sciencedirect.com www.sciencedirect.com

Impact of supraphysiologic MDM2 expression on chromatin networks and therapeutic responses in sarcoma

1
1. scibot 12 May 2023
  
  in Public
  
  RRID:AB_2713958
  
  DOI: 10.1016/j.xgen.2023.100321
  
  Resource: (Cell Signaling Technology Cat# 48818, RRID:AB_2713958)
  
  Curator: @sofiakhan13
  
  SciCrunch record: RRID:AB_2713958
  
  What is this?
  
  RRID:AB_2713958
Visit annotations in context

Tags

RRID:AB_2713958

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2666979X23000897
onlinelibrary.wiley.com onlinelibrary.wiley.com

Snail acetylation by autophagy-derived acetyl-coenzyme A promotes invasion and metastasis of KRAS-LKB1 co-mutated lung cancer cells

1
1. scibot 05 May 2023
  
  in Public
  
  RRID:AB_2713958
  
  DOI: 10.1002/cac2.12332
  
  Resource: (Cell Signaling Technology Cat# 48818, RRID:AB_2713958)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2713958
  
  What is this?
  
  RRID:AB_2713958
Visit annotations in context

Tags

RRID:AB_2713958

Annotators

scibot

URL

onlinelibrary.wiley.com/doi/10.1002/cac2.12332
Apr 2023
www.sciencedirect.com www.sciencedirect.com

The mitochondrial protease OMA1 acts as a metabolic safeguard upon nuclear DNA damage

1
1. scibot 04 Apr 2023
  
  in Public
  
  RRID:AB_2713958
  
  DOI: 10.1016/j.celrep.2023.112332
  
  Resource: (Cell Signaling Technology Cat# 48818, RRID:AB_2713958)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2713958
  
  What is this?
  
  RRID:AB_2713958
Visit annotations in context

Tags

RRID:AB_2713958

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124723003431
Aug 2022
www.sciencedirect.com www.sciencedirect.com

Phosphoproteomics of primary AML patient samples reveals rationale for AKT combination therapy and p53 context to overcome selinexor resistance

1
1. scibot 10 Aug 2022
  
  in Public
  
  RRID:AB_2713958
  
  DOI: 10.1016/j.celrep.2022.111177
  
  Resource: (Cell Signaling Technology Cat# 48818, RRID:AB_2713958)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2713958
  
  What is this?
  
  RRID:AB_2713958
Visit annotations in context

Tags

RRID:AB_2713958

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124722009901
Jul 2021
www.sciencedirect.com www.sciencedirect.com

Lethal Poisoning of Cancer Cells by Respiratory Chain Inhibition plus Dimethyl α-Ketoglutarate

1
1. scibot 31 Jul 2021
  
  in Public
  
  RRID:AB_2713958
  
  DOI: 10.1016/j.celrep.2019.03.058
  
  Resource: (Cell Signaling Technology Cat# 48818, RRID:AB_2713958)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2713958
  
  What is this?
  
  RRID:AB_2713958
Visit annotations in context

Tags

RRID:AB_2713958

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124719303882
May 2021
www.sciencedirect.com www.sciencedirect.com

Sarcomere function activates a p53-dependent DNA damage response that promotes polyploidization and limits in vivo cell engraftment

1
1. scibot 05 May 2021
  
  in Public
  
  RRID:AB_2713958
  
  DOI: 10.1016/j.celrep.2021.109088
  
  Resource: (Cell Signaling Technology Cat# 48818, RRID:AB_2713958)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_2713958
  
  What is this?
  
  RRID:AB_2713958
Visit annotations in context

Tags

RRID:AB_2713958

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124721004216
Oct 2020
febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com

A guide to assessing cellular senescence in vitro and in vivo

1
1. scibot 22 Oct 2020
  
  in Public
  
  RRID:AB_2713958
  
  DOI: 10.1111/febs.15570
  
  Resource: (Cell Signaling Technology Cat# 48818, RRID:AB_2713958)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_2713958
  
  Curator comments: p53 (DO-7) Mouse mAb antibody Cell Signaling Technology Cat# 48818
  
  What is this?
  
  RRID:AB_2713958
Visit annotations in context

Tags

RRID:AB_2713958

Annotators

scibot

URL

febs.onlinelibrary.wiley.com/doi/10.1111/febs.15570
Jan 2020
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Phosphorylation-mediated interactions with TOPBP1 couple 53BP1 and 9-1-1 to control the G1 DNA damage checkpoint

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:AB_2713958
  
  DOI: 10.7554/eLife.44353
  
  Resource: (Cell Signaling Technology Cat# 48818, RRID:AB_2713958)
  
  Curator: @evieth
  
  SciCrunch record: RRID:AB_2713958
  
  What is this?
  
  RRID:AB_2713958 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_2713958

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC6561707/
www.sciencedirect.com www.sciencedirect.com

p53 Is a Master Regulator of Proteostasis in SMARCB1-Deficient Malignant Rhabdoid Tumors

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:AB_2713958
  
  DOI: 10.1016/j.ccell.2019.01.006
  
  Resource: (Cell Signaling Technology Cat# 48818, RRID:AB_2713958)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_2713958
  
  What is this?
  
  RRID:AB_2713958 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:AB_2713958

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1535610819300406